Pharmacokinetic-pharmacodynamic integration and modelling of oxytetracycline administered alone and in combination with carprofen in calves

Research in Veterinary Science

Volumn 94, Issue 3, 2013, Pages 687-694

  Brentnall, C ^a   Cheng, Z ^a   McKellar, Q A ^a,b   Lees, P ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

Author keywords

Calves; Carprofen; Oxytetracycline; Pharmacodynamics; Pharmacokinetics

Indexed keywords

CARPROFEN; OXYTETRACYCLINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; AREA UNDER THE CURVE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERICIDAL ACTIVITY; CALF (BOVINE); COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG TISSUE LEVEL; GROWTH INHIBITION; IN VITRO STUDY; MALE; MANNHEIMIA HAEMOLYTICA; MATHEMATICAL MODEL; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MINIMUM INHIBITORY CONCENTRATION; MONOTHERAPY; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; RECOMMENDED DRUG DOSE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARBAZOLES; CATTLE; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; EXUDATES AND TRANSUDATES; INJECTIONS, INTRAMUSCULAR; MANNHEIMIA HAEMOLYTICA; MICROBIAL SENSITIVITY TESTS; OXYTETRACYCLINE; PNEUMONIA OF CALVES, ENZOOTIC;

BACTERIA (MICROORGANISMS); MANNHEIMIA; MANNHEIMIA HAEMOLYTICA;

EID: 84876148797     PISSN: 00345288     EISSN: 15322661     Source Type: Journal    
DOI: 10.1016/j.rvsc.2013.01.012     Document Type: Article

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