Annexin A1 protein regulates the expression of PMVEC cytoskeletal proteins in CBDL rat serum-induced pulmonary microvascular remodeling

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Yi, Bin ^a   Zeng, Jing ^a   Wang, Guansong ^a   Qian, Guisheng ^a   Lu, Kaizhi ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

ANX A1; Hepatopulmonary syndrome; Pulmonary microvascular endothelial cells

Indexed keywords

ACTIN; ACTIN DEPOLYMERIZING FACTOR; ADENOVIRUS VECTOR; CYTOSKELETON PROTEIN; LIPOCORTIN 1; MESSENGER RNA; TUBULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; BLOOD VESSEL REACTIVITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STIMULATION; COMMON BILE DUCT; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENDOTHELIUM CELL; GENE EXPRESSION; GENETIC TRANSFECTION; HEPATOPULMONARY SYNDROME; HUMAN; HUMAN CELL; LUNG BLOOD VESSEL; NONHUMAN; PHENOTYPE; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PULMONARY MICROVASCULAR ENDOTHELIAL CELL; RAT; REGULATORY MECHANISM; SERUM;

ANIMALS; ANNEXIN A1; CELL NUCLEUS; CELL PROLIFERATION; COMMON BILE DUCT; CYTOKINES; CYTOPLASM; CYTOSKELETON; GENE EXPRESSION REGULATION; HEPATOPULMONARY SYNDROME; HUMANS; LUNG; MICROCIRCULATION; PHENOTYPE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84876143074     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-98     Document Type: Article

References (22)

1. Kammoun T, Ben Abdallah R, Chabchoub I, Bahloul S, Aloulou H, Mahfoudh A, Hachicha M. Hepatopulmonary syndrome and portal hypertension. Tunis Med 2007, 85:170-173.
2. Schenk P, Schoniger-Hekele M, Fuhrmann V, Madl C, Silberhumer G, Muller C. Prognostic significance of the hepatopulmonary syndrome in patients with cirrhosis. Gastroenterology 2003, 125:1042-1052. 10.1016/S0016-5085(03)01207-1, 14517788.
3. Alonso Martinez JL, Zozaya Urmeneta JM, Gutierrez Dubois J, Abinzano Guillen ML, Urbieta Echezarreta MA, Anniccherico Sanchez FJ. Prognostic significance of the hepatopulmonary syndrome in liver cirrhosis. Med Clin (Barc) 2006, 127:133-135.
4. Mandell MS. The diagnosis and treatment of hepatopulmonary syndrome. Clin Liver Dis 2006, 10:387-405. x, 10.1016/j.cld.2006.05.007, 16971268.
5. Sindhu S, Ramesh P, Juneja R, Kabra SK. Hepatopulmonary syndrome, an unusual cause of hypoxemia. Indian J Pediatr 2007, 74:1127-1129. 10.1007/s12098-007-0213-9, 18174653.
6. Fleming GM, Cornell TT, Welling TH, Magee JC, Annich GM. Hepatopulmonary syndrome: use of extracorporeal life support for life-threatening hypoxia following liver transplantation. Liver Transpl 2008, 14:966-970. 10.1002/lt.21477, 18581508.
7. Carter EP, Sato K, Morio Y, McMurtry IF. Inhibition of K(Ca) channels restores blunted hypoxic pulmonary vasoconstriction in rats with cirrhosis. Am J Physiol Lung Cell Mol Physiol 2000, 279:L903-L910.
8. Fallon MB, Abrams GA, McGrath JW, Hou Z, Luo B. Common bile duct ligation in the rat: a model of intrapulmonary vasodilatation and hepatopulmonary syndrome. Am J Physiol 1997, 272:G779-G784.
9. Schraufnagel DE, Malik R, Goel V, Ohara N, Chang SW. Lung capillary changes in hepatic cirrhosis in rats. Am J Physiol 1997, 272:L139-L147.
10. Vaughan RB, Angus PW, Chin-Dusting JP. Evidence for altered vascular responses to exogenous endothelin-1 in patients with advanced cirrhosis with restoration of the normal vasoconstrictor response following successful liver transplantation. Gut 2003, 52:1505-1510. 10.1136/gut.52.10.1505, 1773833, 12970146.
11. Zhang HY, Han DW, Wang XG, Zhao YC, Zhou X, Zhao HZ. Experimental study on the role of endotoxin in the development of hepatopulmonary syndrome. World J Gastroenterol 2005, 11:567-572.
12. Vettukattil JJ, Stumper O. Endothelin-1 in the rat bile duct ligation model of hepatopulmonary syndrome: correlation with pulmonary dysfunction. J Hepatol 1999, 31:192-193.
13. Fallon MB. Mechanisms of pulmonary vascular complications of liver disease: hepatopulmonary syndrome. J Clin Gastroenterol 2005, 39:S138-S142. 10.1097/01.mcg.0000155570.19340.61, 15758649.
14. Schenk P, Madl C, Rezaie-Majd S, Lehr S, Muller C. Methylene blue improves the hepatopulmonary syndrome. Ann Intern Med 2000, 133:701-706. 10.7326/0003-4819-133-9-200011070-00012, 11074903.
15. Krowka MJ, Dickson ER, Cortese DA. Hepatopulmonary syndrome. Clinical observations and lack of therapeutic response to Somatostatin analogue. Chest 1993, 104:515-521. 10.1378/chest.104.2.515, 8101797.
16. Fallon MB, Abrams GA. Pulmonary dysfunction in chronic liver disease. Hepatology 2000, 32:859-865.
17. Mandell MS. Clinical controversies surrounding the diagnosis and treatment of hepatopulmonary syndrome. Minerva Anestesiol 2007, 73:347-355.
18. Wang Z, Yi B, Guo B, Lu K. Changes in expression of transforming growth factor beta-1 during myogenic differentiation of pulmonary microvascular endothelial cells in rats with hepato-pulmonary syndrom. Chin J Anesthesiol 2011, 31:862-864.
19. Guo B, Yi B, Xu S, Lu K. Efect of serum obtained from rat wilh hepatopuimonary syndrome on Akt mRNA and protein expressionin rat pulmonary microvascular endothelial cells. Chin J Anesthesiol 2010, 30:75-78.
20. Chang SW, Ohara N. Pulmonary circulatory dysfunction in rats with biliary cirrhosis. An animal model of the hepatopulmonary syndrome. Am Rev Respir Dis 1992, 145:798-805. 10.1164/ajrccm/145.4_Pt_1.798, 1554205.
21. Parra-Bonilla G, Alvarez DF, Al-Mehdi AB, Alexeyev M, Stevens T. Critical role for lactate dehydrogenase a in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation. Am J Physiol Lung Cell Mol Physiol 2010, 299:L513-L522. 10.1152/ajplung.00274.2009, 2957419, 20675437.
22. Yi B, Cui J, Ning J, Gu J, Wang G, Bai L, Qian G, Lu K. CGMP-dependent protein kinase ialpha transfection inhibits hypoxia-induced migration, phenotype modulation and annexins A1 expression in human pulmonary artery smooth muscle cells. Biochem Biophys Res Commun 2012, 418:598-602. 10.1016/j.bbrc.2012.01.034, 22293199.