-
2
-
-
0024299087
-
The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein
-
Hashimoto C, Hudson KL, Anderson KV. The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein. Cell 1988;52:269-279.
-
(1988)
Cell
, vol.52
, pp. 269-279
-
-
Hashimoto, C.1
Hudson, K.L.2
Anderson, K.V.3
-
3
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/Cactus controls the potent antifungal response in Drosophila adults
-
DOI 10.1016/S0092-8674(00)80172-5
-
Lemaitre B, Nicolas E, Michaut L, et al. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996;86:973-983. (Pubitemid 26336801)
-
(1996)
Cell
, vol.86
, Issue.6
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.-M.4
Hoffmann, J.A.5
-
4
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011;34:637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
5
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai T, Akira S.The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010;11:373-384.
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
6
-
-
79956314622
-
Immune signaling by RIG-I-like receptors
-
Loo YM, GaleM, Jr. Immune signaling by RIG-I-like receptors. Immunity 2011;34:680-692.
-
(2011)
Immunity
, vol.34
, pp. 680-692
-
-
Loo, Y.M.1
Gale Jr., M.2
-
8
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 2009;458:514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
-
9
-
-
77951269392
-
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
-
Rathinam VA, Jiang Z, Waggoner SN, et al. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol 2010;11:395-402.
-
(2010)
Nat Immunol
, vol.11
, pp. 395-402
-
-
Rathinam, V.A.1
Jiang, Z.2
Waggoner, S.N.3
-
10
-
-
79956292569
-
Myeloid C-type lectin receptors in pathogen recognition and host defense
-
Osorio F, Reis e Sousa C.Myeloid C-type lectin receptors in pathogen recognition and host defense. Immunity 2011;34:651-664.
-
(2011)
Immunity
, vol.34
, pp. 651-664
-
-
Osorio, F.1
Reis E Sousa, C.2
-
11
-
-
84859405717
-
Signaling bymyeloid C-type lectin receptors in immunity and homeostasis
-
Sancho D, Reis e Sousa C. Signaling bymyeloid C-type lectin receptors in immunity and homeostasis. Annu Rev Immunol 2012;30:491-529.
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 491-529
-
-
Sancho, D.1
Reis E Sousa, C.2
-
12
-
-
28844441714
-
Robert Koch, the nobel prize, and the ongoing threat of tuberculosis
-
DOI 10.1056/NEJMp058131
-
Kaufmann SH. Robert Koch, the Nobel Prize, and the ongoing threat of tuberculosis. N Engl JMed 2005;353:2423-2426. (Pubitemid 41770161)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.23
, pp. 2423-2426
-
-
Kaufmann, S.H.E.1
-
13
-
-
0017823039
-
Tuberculosis in twins: A re-analysis of the Prophit survey
-
Comstock GW. Tuberculosis in twins: a re-analysis of the Prophit survey. Am Rev Respir Dis 1978;117:621-624. (Pubitemid 8334970)
-
(1978)
American Review of Respiratory Disease
, vol.117
, Issue.4
, pp. 621-624
-
-
Comstock, G.W.1
-
14
-
-
78650101611
-
Leprosy and the human genome
-
Misch EA, Berrington WR, Vary JC, Jr., Hawn TR. Leprosy and the human genome. Microbiol Mol Biol Rev 2010;74:589-620.
-
(2010)
Microbiol Mol Biol Rev
, vol.74
, pp. 589-620
-
-
Misch, E.A.1
Berrington, W.R.2
Vary Jr., J.C.3
Hawn, T.R.4
-
15
-
-
0002580070
-
A twin-family study of susceptibility to poliomyelitis
-
Herndon CN, Jennings RG. A twin-family study of susceptibility to poliomyelitis. Am J Hum Genet 1951;3:17-46.
-
(1951)
Am J Hum Genet
, vol.3
, pp. 17-46
-
-
Herndon, C.N.1
Jennings, R.G.2
-
16
-
-
0024325653
-
Hepatitis B virus marker in Chinese twins
-
Lin TM, Chen CJ, Wu MM, et al. Hepatitis B virus markers in Chinese twins. Anticancer Res 1989;9:737-741. (Pubitemid 19194309)
-
(1989)
Anticancer Research
, vol.9
, Issue.3
, pp. 737-741
-
-
Lin, T.M.1
Chen, C.J.2
Wu, M.M.3
Yang, C.S.4
Chen, J.S.5
Lin, C.C.6
Kwang, T.Y.7
Hsu, S.T.8
Lin, S.Y.9
Hsu, L.C.10
-
17
-
-
0023870774
-
Genetic and environmental influences on premature death in adult adoptees
-
Sorensen TI, Nielsen GG, Andersen PK, Teasdale TW. Genetic and environmental influences on premature death in adult adoptees. N Engl JMed 1988;318:727-732. (Pubitemid 18090256)
-
(1988)
New England Journal of Medicine
, vol.318
, Issue.12
, pp. 727-732
-
-
Sorensen, T.I.A.1
Nielsen, G.G.2
Andersen, P.K.3
Teasdale, T.W.4
-
18
-
-
77049164783
-
Protection afforded by sickle-cell trait against subtertian malareal infection
-
Allison AC. Protection afforded by sickle-cell trait against subtertian malareal infection. Br Med J 1954;1:290-294.
-
(1954)
Br Med J
, vol.1
, pp. 290-294
-
-
Allison, A.C.1
-
19
-
-
0032814653
-
The immunogenetics of resistance tomalaria
-
Hill AV.The immunogenetics of resistance tomalaria. Proc AssocAmPhysicians 1999;111:272-277.
-
(1999)
Proc AssocAmPhysicians
, vol.111
, pp. 272-277
-
-
Hill, A.V.1
-
20
-
-
79953061608
-
Human TLRs and IL-1Rs in host defense: Natural insights from evolutionary, epidemiological, and clinical genetics
-
Casanova JL, Abel L, Quintana-Murci L. Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics. Annu Rev Immunol 2011;29: 447-491.
-
(2011)
Annu Rev Immunol
, vol.29
, pp. 447-491
-
-
Casanova, J.L.1
Abel, L.2
Quintana-Murci, L.3
-
21
-
-
72849122933
-
Fromevolutionary genetics to human immunology: How selection shapes host defence genes
-
Barreiro LB, Quintana-Murci L. Fromevolutionary genetics to human immunology: how selection shapes host defence genes. Nat Rev Genet 2010;11:17-30.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 17-30
-
-
Barreiro, L.B.1
Quintana-Murci, L.2
-
22
-
-
35548956882
-
Immunology in natura: Clinical, epidemiological and evolutionary genetics of infectious diseases
-
DOI 10.1038/ni1535, PII NI1535
-
Quintana-Murci L, Alcais A, Abel L, Casanova JL. Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases. Nat Immunol 2007;8:1165-1171. (Pubitemid 350011752)
-
(2007)
Nature Immunology
, vol.8
, Issue.11
, pp. 1165-1171
-
-
Quintana-Murci, L.1
Alcais, A.2
Abel, L.3
Casanova, J.-L.4
-
23
-
-
34547732069
-
Primary immunodeficiencies: A field in its infancy
-
DOI 10.1126/science.1142963
-
Casanova JL, Abel L. Primary immunodeficiencies: a field in its infancy. Science 2007;317:617-619. (Pubitemid 47229951)
-
(2007)
Science
, vol.317
, Issue.5838
, pp. 617-619
-
-
Casanova, J.-L.1
Abel, L.2
-
24
-
-
47049098425
-
Revisiting human primary immunodeficiencies
-
DOI 10.1111/j.1365-2796.2008.01971.x
-
Casanova JL, Fieschi C, Zhang SY, Abel L. Revisiting human primary immunodeficiencies. J Intern Med 2008;264:115-127. (Pubitemid 351965489)
-
(2008)
Journal of Internal Medicine
, vol.264
, Issue.2
, pp. 115-127
-
-
Casanova, J.-L.1
Fieschi, C.2
Zhang, S.-Y.3
Abel, L.4
-
25
-
-
70349790195
-
Primary immunodeficiencies: Increasing market share
-
Notarangelo LD, Casanova JL. Primary immunodeficiencies: increasing market share. Curr Opin Immunol 2009;21:461-465.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 461-465
-
-
Notarangelo, L.D.1
Casanova, J.L.2
-
26
-
-
0035775726
-
The genomics and genetics of human infectious disease susceptibility
-
DOI 10.1146/annurev.genom.2.1.373
-
Hill AV.The genomics and genetics of human infectious disease susceptibility. Annu RevGenomics HumGenet 2001;2:373-400. (Pubitemid 35265012)
-
(2001)
Annual Review of Genomics and Human Genetics
, vol.2
, pp. 373-400
-
-
Hill, A.V.S.1
-
27
-
-
33845631591
-
Aspects of genetic susceptibility to human infectious diseases
-
DOI 10.1146/annurev.genet.40.110405.090546
-
Hill AV. Aspects of genetic susceptibility to human infectious diseases. Annu Rev Genet 2006;40:469-486. (Pubitemid 44956793)
-
(2006)
Annual Review of Genetics
, vol.40
, pp. 469-486
-
-
Hill, A.V.S.1
-
28
-
-
84857190262
-
Human genetic susceptibility to infectious disease
-
Chapman SJ, Hill AV. Human genetic susceptibility to infectious disease. Nat Rev Genet 2012;13:175-188.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 175-188
-
-
Chapman, S.J.1
Hill, A.V.2
-
29
-
-
79951877143
-
Human genetic susceptibility to intracellular pathogens
-
Vannberg FO, Chapman SJ, Hill AV. Human genetic susceptibility to intracellular pathogens. Immunol Rev 2011;240:105-116.
-
(2011)
Immunol Rev
, vol.240
, pp. 105-116
-
-
Vannberg, F.O.1
Chapman, S.J.2
Hill, A.V.3
-
30
-
-
80155142138
-
Evolution of the TIR domain-containing adaptors in humans: Swinging between constraint and adaptation
-
Fornarino S, Laval G, Barreiro LB, et al. Evolution of the TIR domain-containing adaptors in humans: swinging between constraint and adaptation.Mol Biol Evol 2011;28:3087-3097.
-
(2011)
Mol Biol Evol
, vol.28
, pp. 3087-3097
-
-
Fornarino, S.1
Laval, G.2
Barreiro, L.B.3
-
31
-
-
68249118173
-
Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense
-
Barreiro LB, Ben-Ali M, Quach H, et al. Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense. PLoS Genet 2009;5:e1000562.
-
(2009)
PLoS Genet
, vol.5
-
-
Barreiro, L.B.1
Ben-Ali, M.2
Quach, H.3
-
32
-
-
84863989641
-
The evolutionary landscape of cytosolic microbial sensors in humans
-
Vasseur E, Boniotto M, Patin E, et al. The evolutionary landscape of cytosolic microbial sensors in humans. AmJ HumGenet 2012;91:27-37.
-
(2012)
AmJ HumGenet
, vol.91
, pp. 27-37
-
-
Vasseur, E.1
Boniotto, M.2
Patin, E.3
-
33
-
-
80054948364
-
The selective footprints of viral pressures at the human RIG-I-like receptor family
-
Vasseur E, Patin E, Laval G, et al.The selective footprints of viral pressures at the human RIG-I-like receptor family. HumMol Genet 2011;20:4462-4474.
-
(2011)
HumMol Genet
, vol.20
, pp. 4462-4474
-
-
Vasseur, E.1
Patin, E.2
Laval, G.3
-
34
-
-
67349187318
-
Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells
-
Mancuso G, Gambuzza M, Midiri A, et al. Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells. Nat Immunol 2009;10:587-594.
-
(2009)
Nat Immunol
, vol.10
, pp. 587-594
-
-
Mancuso, G.1
Gambuzza, M.2
Midiri, A.3
-
35
-
-
77954480383
-
Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling
-
Guan Y, Ranoa DR, Jiang S, et al. Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling. J Immunol 2010;184:5094-5103.
-
(2010)
J Immunol
, vol.184
, pp. 5094-5103
-
-
Guan, Y.1
Ranoa, D.R.2
Jiang, S.3
-
36
-
-
36749054015
-
TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans
-
DOI 10.1073/pnas.0704828104
-
Ferwerda B,McCall MB,Alonso S, et al. TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration ofmodern humans. Proc Natl Acad Sci USA 2007;104:16645-16650. (Pubitemid 350211070)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.42
, pp. 16645-16650
-
-
Ferwerda, B.1
McCall, M.B.B.2
Alonso, S.3
Giamarellos-Bourboulis, E.J.4
Mouktaroudi, M.5
Izagirre, N.6
Syafruddin, D.7
Kibiki, G.8
Cristea, T.9
Hijmans, A.10
Hamann, L.11
Israel, S.12
Elghazali, G.13
Troye-Blomberg, M.14
Kumpf, O.15
Maiga, B.16
Dolo, A.17
Doumbo, O.18
Hermsen, C.C.19
Stalenhoef, A.F.H.20
Van Crevel, R.21
Brunner, H.G.22
Oh, D.-Y.23
Schumann, R.R.24
De La Rua, C.25
Sauerwein, R.26
Kullberg, B.-J.27
Van Der Ven, A.J.A.M.28
Van Der Meer, J.W.M.29
Netea, M.G.30
more..
-
37
-
-
0037111078
-
Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections
-
DOI 10.1086/344893
-
Agnese DM, Calvano JE, Hahm SJ, et al. Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infections. J Infect Dis 2002;186:1522-1525. (Pubitemid 35286126)
-
(2002)
Journal of Infectious Diseases
, vol.186
, Issue.10
, pp. 1522-1525
-
-
Agnese, D.M.1
Calvano, J.E.2
Hahm, S.J.3
Coyle, S.M.4
Corbett, S.A.5
Calvano, S.E.6
Lowry, S.F.7
-
38
-
-
0037071251
-
Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
-
Lorenz E,Mira JP, Frees KL, Schwartz DA. Relevance ofmutations in the TLR4 receptor in patients with gram-negative septic shock. Arch InternMed 2002;162:1028-1032. (Pubitemid 34492532)
-
(2002)
Archives of Internal Medicine
, vol.162
, Issue.9
, pp. 1028-1032
-
-
Lorenz, E.1
Mira, J.P.2
Frees, K.L.3
Schwartz, D.A.4
-
39
-
-
8744301714
-
TLR4 and TNF-α polymorphisms are associated with an increased risk for severe sepsis following burn injury
-
DOI 10.1136/jmg.2004.021600
-
Barber RC,Aragaki CC, Rivera-Chavez FA, et al. TLR4 andTNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury. JMed Genet 2004;41:808-813. (Pubitemid 39524306)
-
(2004)
Journal of Medical Genetics
, vol.41
, Issue.11
, pp. 808-813
-
-
Barber, R.C.1
Aragaki, C.C.2
Rivera-Chavez, F.A.3
Purdue, G.F.4
Hunt, J.L.5
Horton, J.W.6
-
40
-
-
59149086761
-
A toll-like receptor 4 variant is associated with fatal outcome in children with invasive meningococcal disease
-
Faber J, Henninger N, Finn A, et al. A toll-like receptor 4 variant is associated with fatal outcome in children with invasive meningococcal disease. Acta Paediatr 2009;98:548-552.
-
(2009)
Acta Paediatr
, vol.98
, pp. 548-552
-
-
Faber, J.1
Henninger, N.2
Finn, A.3
-
41
-
-
33644541916
-
Human toll-like receptor 4 mutations are associated with susceptibility to invasive meningococcal disease in infancy
-
DOI 10.1097/01.inf.0000195595.22547.fe, PII 0000645420060100000020
-
Faber J,Meyer CU, Gemmer C, et al. Human toll-like receptor 4mutations are associated with susceptibility to invasivemeningococcal disease in infancy. Pediatr Infect Dis J 2006;25:80-81. (Pubitemid 43361484)
-
(2006)
Pediatric Infectious Disease Journal
, vol.25
, Issue.1
, pp. 80-81
-
-
Faber, J.1
Meyer, C.U.2
Gemmer, C.3
Russo, A.4
Finn, A.5
Murdoch, C.6
Zenz, W.7
Mannhalter, C.8
Zabel, B.U.9
Schmitt, H.-J.10
Habermehl, P.11
Zepp, F.12
Knuf, M.13
-
42
-
-
84863599908
-
Assessment of Toll-like receptor-4 gene polymorphism on pyelonephritis and renal scar
-
Akil I, Ozkinay F, Onay H, et al. Assessment of Toll-like receptor-4 gene polymorphism on pyelonephritis and renal scar. Int J Immunogenet 2012;39:303-307.
-
(2012)
Int J Immunogenet
, vol.39
, pp. 303-307
-
-
Akil, I.1
Ozkinay, F.2
Onay, H.3
-
43
-
-
80054087240
-
Nasopharyngeal bacterial colonization and gene polymorphisms ofmannose-binding lectin and toll-like receptors 2 and 4 in infants
-
Vuononvirta J, Toivonen L, Grondahl-Yli-Hannuksela K, et al. Nasopharyngeal bacterial colonization and gene polymorphisms ofmannose-binding lectin and toll-like receptors 2 and 4 in infants. PLoS One 2011;6:e26198.
-
(2011)
PLoS One
, vol.6
-
-
Vuononvirta, J.1
Toivonen, L.2
Grondahl-Yli-Hannuksela, K.3
-
44
-
-
84855964739
-
Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis
-
West TE, Chierakul W, ChantratitaN, et al. Toll-like receptor 4 region genetic variants are associated with susceptibility to melioidosis. Genes Immun 2012;13:38-46.
-
(2012)
Genes Immun
, vol.13
, pp. 38-46
-
-
West, T.E.1
Chierakul, W.2
Chantratita, N.3
-
45
-
-
0038466078
-
Effects of functional toll-like receptor-4 mutations on the immune response to human and experimental sepsis
-
DOI 10.1046/j.1365-2567.2003.01674.x
-
Feterowski C, Emmanuilidis K, Miethke T, et al. Effects of functional Toll-like receptor-4 mutations on the immune response to human and experimental sepsis. Immunology 2003;109: 426-431. (Pubitemid 36783269)
-
(2003)
Immunology
, vol.109
, Issue.3
, pp. 426-431
-
-
Feterowski, C.1
Emmanuilidis, K.2
Miethke, T.3
Gerauer, K.4
Rump, M.5
Ulm, K.6
Holzmann, B.7
Weighardt, H.8
-
46
-
-
35448984009
-
Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome fromGramnegative sepsis
-
Jessen KM, Lindboe SB, Petersen AL, et al. Common TNF-alpha, IL-1 beta, PAI-1, uPA, CD14 and TLR4 polymorphisms are not associated with disease severity or outcome fromGramnegative sepsis. BMC Infect Dis 2007;7:108.
-
(2007)
BMC Infect Dis
, vol.7
, pp. 108
-
-
Jessen, K.M.1
Lindboe, S.B.2
Petersen, A.L.3
-
47
-
-
0038202199
-
Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome
-
DOI 10.1042/BST0310652
-
Child NJ, Yang IA, Pulletz MC, et al. Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome. Biochem Soc Trans 2003;31:652-653. (Pubitemid 36750749)
-
(2003)
Biochemical Society Transactions
, vol.31
, Issue.3
, pp. 652-653
-
-
Child, N.J.A.1
Yang, I.A.2
Pulletz, M.C.K.3
De Courcy-Golder, K.4
Andrews, A.-L.5
Pappachan, V.J.6
Holloway, J.W.7
-
48
-
-
14044259411
-
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
-
DOI 10.1073/pnas.0409831102
-
Hawn TR, Verbon A, Janer M, et al. Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease. Proc Natl Acad Sci USA 2005;102:2487-2489. (Pubitemid 40279403)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.7
, pp. 2487-2489
-
-
Hawn, T.R.1
Verbon, A.2
Janer, M.3
Zhao, L.P.4
Beutler, B.5
Aderem, A.6
-
49
-
-
0038578610
-
Activation and regulation of Toll-like receptors 2 and 1 in human leprosy
-
DOI 10.1038/nm864
-
Krutzik SR, Ochoa MT, Sieling PA, et al. Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. NatMed 2003;9:525-532. (Pubitemid 36597097)
-
(2003)
Nature Medicine
, vol.9
, Issue.5
, pp. 525-532
-
-
Krutzik, S.R.1
Ochoa, M.T.2
Sieling, P.A.3
Uematsu, S.4
Ng, Y.W.5
Legaspi, A.6
Liu, P.T.7
Cole, S.T.8
Godowski, P.J.9
Maeda, Y.10
Sarno, E.N.11
Norgard, M.V.12
Brennan, P.J.13
Akira, S.14
Rea, T.H.15
Modlin, R.L.16
-
50
-
-
67349217383
-
TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis
-
Drage MG, Pecora ND, Hise AG, et al. TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis. Cell Immunol 2009;258:29-37.
-
(2009)
Cell Immunol
, vol.258
, pp. 29-37
-
-
Drage, M.G.1
Pecora, N.D.2
Hise, A.G.3
-
52
-
-
79952220311
-
Innate immune effectors in mycobacterial infection
-
Saiga H, Shimada Y, Takeda K. Innate immune effectors in mycobacterial infection. Clin Dev Immunol 2011;2011:347594.
-
(2011)
Clin Dev Immunol
, vol.2011
, pp. 347594
-
-
Saiga, H.1
Shimada, Y.2
Takeda, K.3
-
53
-
-
34250205895
-
Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy
-
Johnson CM, Lyle EA, Omueti KO, et al. Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy. J Immunol 2007;178:7520-7524. (Pubitemid 46898019)
-
(2007)
Journal of Immunology
, vol.178
, Issue.12
, pp. 7520-7524
-
-
Johnson, C.M.1
Lyle, E.A.2
Omueti, K.O.3
Stepensky, V.A.4
Yegin, O.5
Alpsoy, E.6
Hamann, L.7
Schumann, R.R.8
Tapping, R.I.9
-
54
-
-
77957654090
-
Leprosy and the adaptation of human toll-like receptor 1
-
Wong SH, Gochhait S,Malhotra D, et al. Leprosy and the adaptation of human toll-like receptor 1. PLoS Path 2010;6:e1000979.
-
(2010)
PLoS Path
, vol.6
-
-
Wong, S.H.1
Gochhait, S.2
Malhotra, D.3
-
55
-
-
67650486394
-
Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions
-
Schuring RP, Hamann L, Faber WR, et al. Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions. J Infect Dis 2009;199:1816-1819.
-
(2009)
J Infect Dis
, vol.199
, pp. 1816-1819
-
-
Schuring, R.P.1
Hamann, L.2
Faber, W.R.3
-
56
-
-
39149093678
-
Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy
-
DOI 10.1086/524688
-
Bochud PY,Hawn TR, SiddiquiMR, et al. Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy. J Infect Dis 2008;197:253-261. (Pubitemid 351263444)
-
(2008)
Journal of Infectious Diseases
, vol.197
, Issue.2
, pp. 253-261
-
-
Bochud, P.-Y.1
Hawn, T.R.2
Siddiqui, M.R.3
Saunderson, P.4
Britton, S.5
Abraham, I.6
Argaw, A.T.7
Janer, M.8
Zhao, L.P.9
Kaplan, G.10
Aderem, A.11
-
57
-
-
1042269515
-
The Arg753Gln polymorphism of the human Toll-like receptor 2 gene in tuberculosis disease
-
DOI 10.1183/09031936.03.00061703
-
Ogus AC, Yoldas B, Ozdemir T, et al.The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease. Eur Respir J 2004;23:219-223. (Pubitemid 38195506)
-
(2004)
European Respiratory Journal
, vol.23
, Issue.2
, pp. 219-223
-
-
Ogus, A.C.1
Yoldas, B.2
Ozdemir, T.3
Uguz, A.4
Olcen, S.5
Kaser, I.6
Coskun, M.7
Cilli, A.8
Yegin, O.9
-
58
-
-
42949132877
-
Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease
-
Ma X, Liu Y, Gowen BB, et al. Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease. PLoS One 2007;2:e1318.
-
(2007)
PLoS One
, vol.2
-
-
Ma, X.1
Liu, Y.2
Gowen, B.B.3
-
59
-
-
33644761926
-
The association between microsatellite polymorphisms in intron II of the human Toll-like receptor 2 gene and tuberculosis among Koreans
-
DOI 10.1038/sj.gene.6364274, PII 6364274
-
Yim JJ, Lee HW, Lee HS, et al. The association between microsatellite polymorphisms in intron II of the human Toll-like receptor 2 gene and tuberculosis among Koreans. Genes Immun 2006;7:150-155. (Pubitemid 43336057)
-
(2006)
Genes and Immunity
, vol.7
, Issue.2
, pp. 150-155
-
-
Yim, J.-J.1
Lee, H.W.2
Lee, H.S.3
Kim, Y.W.4
Han, S.K.5
Shim, Y.-S.6
Holland, S.M.7
-
60
-
-
77349111274
-
Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts
-
Chen YC, Hsiao CC, Chen CJ, et al. Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts. BMCMed Genet 2010;11:17.
-
(2010)
BMCMed Genet
, vol.11
, pp. 17
-
-
Chen, Y.C.1
Hsiao, C.C.2
Chen, C.J.3
-
61
-
-
42949174158
-
The influence of host and bacterial genotype on the development of disseminated disease withMycobacterium tuberculosis
-
Caws M,Thwaites G, Dunstan S, et al.The influence of host and bacterial genotype on the development of disseminated disease withMycobacterium tuberculosis. PLoS Path 2008;4:e1000034.
-
(2008)
PLoS Path
, vol.4
-
-
Caws, M.1
Thwaites, G.2
Dunstan, S.3
-
62
-
-
79954621842
-
Arg753Gln polymorphism of the human Toll-like receptor 2 gene from infection to disease in pediatric tuberculosis
-
Dalgic N, TekinD, Kayaalti Z, et al. Arg753Gln polymorphism of the human Toll-like receptor 2 gene from infection to disease in pediatric tuberculosis. Hum Immunol 2011;72:440-445.
-
(2011)
Hum Immunol
, vol.72
, pp. 440-445
-
-
Dalgic, N.1
Tekin, D.2
Kayaalti, Z.3
-
63
-
-
77954332995
-
Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population
-
Najmi N, Kaur G, Sharma SK, Mehra NK. Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population. Tissue Antigens 2010;76:102-109.
-
(2010)
Tissue Antigens
, vol.76
, pp. 102-109
-
-
Najmi, N.1
Kaur, G.2
Sharma, S.K.3
Mehra, N.K.4
-
64
-
-
79961034496
-
Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression
-
Uciechowski P, Imhoff H, Lange C, et al. Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression. J Leukoc Biol 2011;90: 377-388.
-
(2011)
J Leukoc Biol
, vol.90
, pp. 377-388
-
-
Uciechowski, P.1
Imhoff, H.2
Lange, C.3
-
65
-
-
55449113946
-
Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis
-
Davila S, Hibberd ML, Hari Dass R, et al. Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis. PLoS Genet 2008;4:e1000218.
-
(2008)
PLoS Genet
, vol.4
-
-
Davila, S.1
Hibberd, M.L.2
Hari Dass, R.3
-
66
-
-
77449122899
-
Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians African-Americans, andWest Africans
-
Velez DR, Wejse C, Stryjewski ME, et al. Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, andWest Africans.Hum Genet 2010;127:65-73.
-
(2010)
Hum Genet
, vol.127
, pp. 65-73
-
-
Velez, D.R.1
Wejse, C.2
Stryjewski, M.E.3
-
67
-
-
84856605757
-
Association of TLR polymorphisms with development of tuberculosis in Indonesian females
-
Kobayashi K, Yuliwulandari R, YanaiH, et al. Association of TLR polymorphisms with development of tuberculosis in Indonesian females. Tissue Antigens 2012;79:190-197.
-
(2012)
Tissue Antigens
, vol.79
, pp. 190-197
-
-
Kobayashi, K.1
Yuliwulandari, R.2
Yanai, H.3
-
68
-
-
23444453397
-
Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage lyme disease
-
Schroder NW, Diterich I, Zinke A, et al. Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease. J Immunol 2005;175:2534-2540. (Pubitemid 41113865)
-
(2005)
Journal of Immunology
, vol.175
, Issue.4
, pp. 2534-2540
-
-
Schroder, N.W.J.1
Diterich, I.2
Zinke, A.3
Eckert, J.4
Draing, C.5
Baehr, V.V.6
Hassler, D.7
Priem, S.8
Hahn, K.9
Michelsen, K.S.10
Hartung, T.11
Burmester, G.R.12
Gobel, U.B.13
Hermann, C.14
Schumann, R.R.15
-
69
-
-
10744226016
-
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
-
DOI 10.1084/jem.20031220
-
Hawn TR, Verbon A, Lettinga KD, et al. A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J Exp Med 2003;198:1563-1572. (Pubitemid 37467170)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.10
, pp. 1563-1572
-
-
Hawn, T.R.1
Verbon, A.2
Lettinga, K.D.3
Zhao, L.P.4
Li, S.S.5
Laws, R.J.6
Skerrett, S.J.7
Beutler, B.8
Schroeder, L.9
Nachman, A.10
Ozinsky, A.11
Smith, K.D.12
Aderem, A.13
-
70
-
-
33746637209
-
Characterization and functional investigation of single nucleotide polymorphisms (SNPs) in the human TLR5 gene
-
Merx S, ZimmerW,Neumaier M, Ahmad-Nejad P. Characterization and functional investigation of single nucleotide polymorphisms (SNPs) in the human TLR5 gene. HumMutat 2006;27:293.
-
(2006)
HumMutat
, vol.27
, pp. 293
-
-
Merx, S.1
Zimmer, W.2
Neumaier, M.3
Ahmad-Nejad, P.4
-
71
-
-
84876100365
-
Fungal pathogens-a sweet and sour treat for toll-like receptors
-
Bourgeois C, Kuchler K. Fungal pathogens-a sweet and sour treat for toll-like receptors. Front Cell InfectMicrobiol 2012;2:142.
-
(2012)
Front Cell InfectMicrobiol
, vol.2
, pp. 142
-
-
Bourgeois, C.1
Kuchler, K.2
-
72
-
-
84863238893
-
Toll-like receptor 1 polymorphisms increase susceptibility to candidemia
-
Plantinga TS, Johnson MD, Scott WK, et al. Toll-like receptor 1 polymorphisms increase susceptibility to candidemia. J Infect Dis 2012;205:934-943.
-
(2012)
J Infect Dis
, vol.205
, pp. 934-943
-
-
Plantinga, T.S.1
Johnson, M.D.2
Scott, W.K.3
-
73
-
-
33746042266
-
Toll-like receptor 4 Asp299Gly/Thr399Ile polymorphisms are a risk factor for Candida bloodstream infection
-
Van der Graaf CA, Netea MG, Morre SA, et al. Toll-like receptor 4 Asp299Gly/Thr399Ile polymorphisms are a risk factor for Candida bloodstream infection. Eur Cytokine Netw 2006;17:29-34.
-
(2006)
Eur Cytokine Netw
, vol.17
, pp. 29-34
-
-
Van Der Graaf, C.A.1
Netea, M.G.2
Morre, S.A.3
-
74
-
-
33745492610
-
TLR1 and TLR6 polymorphisms are associated with susceptibility to invasive aspergillosis after allogeneic stem cell transplantation
-
Kesh S, Mensah NY, Peterlongo P, et al. TLR1 and TLR6 polymorphisms are associated with susceptibility to invasive aspergillosis after allogeneic stem cell transplantation. Ann NY Acad Sci 2005;1062:95-103.
-
(2005)
Ann NY Acad Sci
, vol.1062
, pp. 95-103
-
-
Kesh, S.1
Mensah, N.Y.2
Peterlongo, P.3
-
75
-
-
54949144335
-
Toll-like receptor 4 polymorphisms and aspergillosis in stemcell transplantation
-
Bochud PY, Chien JW,Marr KA, et al. Toll-like receptor 4 polymorphisms and aspergillosis in stemcell transplantation. N Engl JMed 2008;359:1766-1777.
-
(2008)
N Engl JMed
, vol.359
, pp. 1766-1777
-
-
Bochud, P.Y.1
Chien, J.W.2
Marr, K.A.3
-
76
-
-
40049086204
-
Polymorphisms in toll-like receptor genes and susceptibility to pulmonary aspergillosis
-
DOI 10.1086/526500
-
Carvalho A, Pasqualotto AC, Pitzurra L, et al. Polymorphisms in toll-like receptor genes and susceptibility to pulmonary aspergillosis. J Infect Dis 2008;197:618-621. (Pubitemid 351321541)
-
(2008)
Journal of Infectious Diseases
, vol.197
, Issue.4
, pp. 618-621
-
-
Carvalho, A.1
Pasqualotto, A.C.2
Pitzurra, L.3
Romani, L.4
Denning, D.W.5
Rodrigues, F.6
-
77
-
-
79953686785
-
Influence of polymorphisms in innate immunity genes on susceptibility to invasive aspergillosis after stem cell transplantation
-
de Boer MG, Jolink H, Halkes CJ, et al. Influence of polymorphisms in innate immunity genes on susceptibility to invasive aspergillosis after stem cell transplantation. PLoS One 2011;6:e18403.
-
(2011)
PLoS One
, vol.6
-
-
De Boer, M.G.1
Jolink, H.2
Halkes, C.J.3
-
78
-
-
34547126686
-
Effects of single nucleotide polymorphisms on toll-like receptor 3 activity and expression in cultured cells
-
DOI 10.1074/jbc.M700209200
-
Ranjith-Kumar CT, Miller W, Sun J, et al. Effects of single nucleotide polymorphisms on Toll-like receptor 3 activity and expression in cultured cells. J Biol Chem 2007;282:17696-17705. (Pubitemid 47100325)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.24
, pp. 17696-17705
-
-
Ranjith-Kumar, C.T.1
Miller, W.2
Sun, J.3
Xiong, J.4
Santos, J.5
Yarbrough, I.6
Lamb, R.J.7
Mills, J.8
Duffy, K.E.9
Hoose, S.10
Cunningham, M.11
Holzenburg, A.12
Mbow, M.L.13
Sarisky, R.T.14
Kao, C.C.15
-
79
-
-
79551469099
-
The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity
-
NahumA, Dadi H, Bates A, Roifman CM. The L412F variant of Toll-like receptor 3 (TLR3) is associated with cutaneous candidiasis, increased susceptibility to cytomegalovirus, and autoimmunity. J Allergy Clin Immunol 2011;127:528-531.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 528-531
-
-
Nahuma Dadi, H.1
Bates, A.2
Roifman, C.M.3
-
80
-
-
84857506024
-
The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity
-
Nahum A, Dadi H, Bates A, Roifman CM. The biological significance of TLR3 variant, L412F, in conferring susceptibility to cutaneous candidiasis, CMV and autoimmunity. Autoimmun Rev 2012;11:341-347.
-
(2012)
Autoimmun Rev
, vol.11
, pp. 341-347
-
-
Nahum, A.1
Dadi, H.2
Bates, A.3
Roifman, C.M.4
-
81
-
-
84856267624
-
TLR3 essentially promotes protective class I-restrictedmemoryCD8(+) T-cell responses toAspergillus fumigatus inhematopoietic transplanted patients
-
Carvalho A, De Luca A, Bozza S, et al. TLR3 essentially promotes protective class I-restrictedmemoryCD8(+) T-cell responses toAspergillus fumigatus inhematopoietic transplanted patients.Blood 2012;119:967-977.
-
(2012)
Blood
, vol.119
, pp. 967-977
-
-
Carvalho, A.1
De Luca, A.2
Bozza, S.3
-
82
-
-
32944464648
-
Pathogen recognition and innateimmunity
-
Akira S,Uematsu S, Takeuchi O. Pathogen recognition and innateimmunity. Cell 2006;124:783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
83
-
-
34548699323
-
TLR3 deficiency in patients with herpes simplex encephalitis
-
DOI 10.1126/science.1139522
-
Zhang SY, Jouanguy E,Ugolini S, et al. TLR3 deficiency in patientswith herpes simplex encephalitis. Science 2007;317:1522-1527. (Pubitemid 47417427)
-
(2007)
Science
, vol.317
, Issue.5844
, pp. 1522-1527
-
-
Zhang, S.-Y.1
Jouanguy, E.2
Ugolini, S.3
Smahi, A.4
Elain, G.5
Romero, P.6
Segal, D.7
Sancho-Shimizu, V.8
Lorenzo, L.9
Puel, A.10
Picard, C.11
Chapgier, A.12
Plancoulaine, S.13
Titeux, M.14
Cognet, C.15
Von Bernuth, H.16
Ku, C.-L.17
Casrouge, A.18
Zhang, X.-X.19
Barreiro, L.20
Leonard, J.21
Hamilton, C.22
Lebon, P.23
Heron, B.24
Vallee, L.25
Quintana-Murci, L.26
Hovnanian, A.27
Rozenberg, F.28
Vivier, E.29
Geissmann, F.30
Tardieu, M.31
Abel, L.32
Casanova, J.-L.33
more..
-
84
-
-
80555144890
-
Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity
-
Guo Y, Audry M, Ciancanelli M, et al. Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity. J Exp Med 2011;208:2083-2098.
-
(2011)
J Exp Med
, vol.208
, pp. 2083-2098
-
-
Guo, Y.1
Audry, M.2
Ciancanelli, M.3
-
85
-
-
84856013847
-
A common polymorphism in TLR3 confers natural resistance to HIV-1 infection
-
Sironi M, Biasin M, Cagliani R, et al. A common polymorphism in TLR3 confers natural resistance to HIV-1 infection. J Immunol 2012;188:818-823.
-
(2012)
J Immunol
, vol.188
, pp. 818-823
-
-
Sironi, M.1
Biasin, M.2
Cagliani, R.3
-
86
-
-
67649979735
-
TLR3 gene polymorphisms and liver diseasemanifestations in chronic hepatitis C
-
Askar E, Bregadze R,Mertens J, et al. TLR3 gene polymorphisms and liver diseasemanifestations in chronic hepatitis C. JMed Virol 2009;81:1204-1211.
-
(2009)
JMed Virol
, vol.81
, pp. 1204-1211
-
-
Askar, E.1
Bregadze, R.2
Mertens, J.3
-
87
-
-
84874903972
-
Impaired TLR3-mediated immune responses from macrophages of patients chronically infected with Hepatitis C virus
-
Qian F, Bolen CR, Jing C, et al. Impaired TLR3-mediated immune responses from macrophages of patients chronically infected with Hepatitis C virus. Clin Vaccine Immunol 2013;20:146-155.
-
(2013)
Clin Vaccine Immunol
, vol.20
, pp. 146-155
-
-
Qian, F.1
Bolen, C.R.2
Jing, C.3
-
88
-
-
84864122520
-
Toll-like receptor 3 polymorphism and its association with hepatitis B virus infection in Saudi Arabian patients
-
Al-Qahtani A, Al-Ahdal M, Abdo A, et al. Toll-like receptor 3 polymorphism and its association with hepatitis B virus infection in Saudi Arabian patients. JMed Virol 2012;84:1353-1359.
-
(2012)
JMed Virol
, vol.84
, pp. 1353-1359
-
-
Al-Qahtani, A.1
Al-Ahdal, M.2
Abdo, A.3
-
89
-
-
84865470773
-
Toll-like receptor 3 L412F polymorphisms in infants with bronchiolitis and postbronchiolitis wheezing
-
Nuolivirta K, He Q, Vuononvirta J, et al. Toll-like receptor 3 L412F polymorphisms in infants with bronchiolitis and postbronchiolitis wheezing. Pediatr Infect Dis J 2012;31:920-923.
-
(2012)
Pediatr Infect Dis J
, vol.31
, pp. 920-923
-
-
Nuolivirta, K.1
He, Q.2
Vuononvirta, J.3
-
90
-
-
84886952646
-
Association between a functional polymorphism in Toll-like receptor 3 and chronic hepatitis C in liver transplant recipients
-
Lee SO, Brown RA, Razonable RR. Association between a functional polymorphism in Toll-like receptor 3 and chronic hepatitis C in liver transplant recipients. Transpl Infect Dis 2012.
-
(2012)
Transpl Infect Dis
-
-
Lee, S.O.1
Brown, R.A.2
Razonable, R.R.3
-
91
-
-
33645982220
-
A missensemutation of the Toll-like receptor 3 gene in a patient with influenza-associated encephalopathy
-
Hidaka F,Matsuo S,Muta T, et al. A missensemutation of the Toll-like receptor 3 gene in a patient with influenza-associated encephalopathy. Clin Immunol 2006;119:188-194.
-
(2006)
Clin Immunol
, vol.119
, pp. 188-194
-
-
Hidaka, F.1
Matsuo, S.2
Muta, T.3
-
92
-
-
59849086382
-
A frequent functional toll-like receptor 7 polymorphism is associated with accelerated HIV-1 disease progression
-
Oh DY, Baumann K, Hamouda O, et al. A frequent functional toll-like receptor 7 polymorphism is associated with accelerated HIV-1 disease progression. AIDS 2009;23:297-307.
-
(2009)
AIDS
, vol.23
, pp. 297-307
-
-
Oh, D.Y.1
Baumann, K.2
Hamouda, O.3
-
93
-
-
50949083798
-
A functional toll-like receptor 8 variant is associated with HIV disease restriction
-
Oh DY, Taube S, Hamouda O, et al. A functional toll-like receptor 8 variant is associated with HIV disease restriction. J Infect Dis 2008;198:701-709.
-
(2008)
J Infect Dis
, vol.198
, pp. 701-709
-
-
Oh, D.Y.1
Taube, S.2
Hamouda, O.3
-
94
-
-
33847021903
-
Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection
-
Bochud PY,HersbergerM, Taffe P, et al. Polymorphisms in Toll-like receptor 9 influence the clinical course of HIV-1 infection. AIDS 2007;21:441-446.
-
(2007)
AIDS
, vol.21
, pp. 441-446
-
-
Bochud, P.Y.1
Hersberger, M.2
Taffe, P.3
-
95
-
-
55249122420
-
Influence of the Toll-like receptor 9 1635A/G polymorphism on the CD4 count, HIV viral load, and clinical progression
-
Soriano-Sarabia N, Vallejo A, Ramirez-Lorca R, et al. Influence of the Toll-like receptor 9 1635A/G polymorphism on the CD4 count, HIV viral load, and clinical progression. J Acquir Immune Defic Syndr 2008;49:128-135.
-
(2008)
J Acquir Immune Defic Syndr
, vol.49
, pp. 128-135
-
-
Soriano-Sarabia, N.1
Vallejo, A.2
Ramirez-Lorca, R.3
-
96
-
-
80054856821
-
The role of polymorphisms in Toll-like receptors and their associated intracellular signaling genes inmeasles vaccineimmunity
-
Ovsyannikova IG, Haralambieva IH, Vierkant RA, et al. The role of polymorphisms in Toll-like receptors and their associated intracellular signaling genes inmeasles vaccineimmunity.HumGenet 2011;130:547-561.
-
(2011)
HumGenet
, vol.130
, pp. 547-561
-
-
Ovsyannikova, I.G.1
Haralambieva, I.H.2
Vierkant, R.A.3
-
97
-
-
34547622158
-
Polymorphisms in TLR2 are associated with increased viral shedding and lesional rate in patients with genital herpes simplex virus type 2 infection
-
DOI 10.1086/519693
-
Bochud PY, Magaret AS, Koelle DM, et al. Polymorphisms in TLR2 are associated with increased viral shedding and lesional rate in patients with genital herpes simplex virus Type 2 infection. J Infect Dis 2007;196:505-509. (Pubitemid 47206095)
-
(2007)
Journal of Infectious Diseases
, vol.196
, Issue.4
, pp. 505-509
-
-
Bochud, P.-Y.1
Magaret, A.S.2
Koelle, D.M.3
Aderem, A.4
Wald, A.5
-
98
-
-
34248190825
-
Relationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation
-
DOI 10.1086/514339
-
Kijpittayarit S, Eid AJ, Brown RA, et al. Relationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation. Clin Infect Dis 2007;44:1315-1320. (Pubitemid 46717293)
-
(2007)
Clinical Infectious Diseases
, vol.44
, Issue.10
, pp. 1315-1320
-
-
Kijpittayarit, S.1
Eid, A.J.2
Brown, R.A.3
Paya, C.V.4
Razonable, R.R.5
-
99
-
-
84863012906
-
Homozygosity for the toll-like receptor 2 R753Q singlenucleotide polymorphism is a risk factor for cytomegalovirus disease after liver transplantation
-
Kang SH, Abdel-Massih RC, Brown RA, et al.Homozygosity for the toll-like receptor 2 R753Q singlenucleotide polymorphism is a risk factor for cytomegalovirus disease after liver transplantation. J Infect Dis 2012;205:639-646.
-
(2012)
J Infect Dis
, vol.205
, pp. 639-646
-
-
Kang, S.H.1
Abdel-Massih, R.C.2
Brown, R.A.3
-
100
-
-
2542485274
-
Association between common toll-like receptor 4 mutations and severe respiratory syncytial virus disease
-
DOI 10.1086/420830
-
TalG,Mandelberg A,Dalal I, et al. Association between common Toll-like receptor 4mutations and severe respiratory syncytial virus disease. J Infect Dis 2004;189:2057-2063. (Pubitemid 38692286)
-
(2004)
Journal of Infectious Diseases
, vol.189
, Issue.11
, pp. 2057-2063
-
-
Tal, G.1
Mandelberg, A.2
Dalal, I.3
Cesar, K.4
Somekh, E.5
Tal, A.6
Oron, A.7
Itskovich, S.8
Ballin, A.9
Houri, S.10
Beigelman, A.11
Lider, O.12
Rechavi, G.13
Amariglio, N.14
-
101
-
-
34249338014
-
Common human Toll-like receptor 4 polymorphisms-Role in susceptibility to respiratory syncytial virus infection and functional immunological relevance
-
DOI 10.1016/j.clim.2007.03.003, PII S1521661607000599
-
Paulus SC,HirschfeldAF, Victor RE, et al.Commonhuman Toll-like receptor 4 polymorphisms-role in susceptibility to respiratory syncytial virus infection and functional immunological relevance. Clin Immunol 2007;123:252-257. (Pubitemid 46818131)
-
(2007)
Clinical Immunology
, vol.123
, Issue.3
, pp. 252-257
-
-
Paulus, S.C.1
Hirschfeld, A.F.2
Victor, R.E.3
Brunstein, J.4
Thomas, E.5
Turvey, S.E.6
-
102
-
-
77954675294
-
TLR9 andendogenous adjuvants of the wholeblood-stagemalaria vaccine
-
CobanC,Horii T, Akira S, Ishii KJ.TLR9 andendogenous adjuvants of the wholeblood-stagemalaria vaccine. Expert Rev Vaccines 2010;9:775-784.
-
(2010)
Expert Rev Vaccines
, vol.9
, pp. 775-784
-
-
Coban, C.1
Horii, T.2
Akira, S.3
Ishii, K.J.4
-
103
-
-
74049121298
-
Immunogenicity of whole-parasite vaccines against Plasmodium falciparuminvolvesmalarial hemozoin and host TLR9
-
Coban C, Igari Y, Yagi M, et al. Immunogenicity of whole-parasite vaccines against Plasmodium falciparuminvolvesmalarial hemozoin and host TLR9. Cell HostMicrobe 2010;7:50-61.
-
(2010)
Cell HostMicrobe
, vol.7
, pp. 50-61
-
-
Coban, C.1
Igari, Y.2
Yagi, M.3
-
104
-
-
34548021449
-
Immune system recognition of Trypanosoma cruzi
-
DOI 10.1016/j.coi.2007.06.003, PII S0952791507001069
-
Tarleton RL. Immune system recognition of Trypanosoma cruzi. Curr Opin Immunol 2007;19:430-434. (Pubitemid 47284855)
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.4
, pp. 430-434
-
-
Tarleton, R.L.1
-
105
-
-
6344241296
-
Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi
-
Oliveira AC, Peixoto JR, de Arruda LB, et al. Expression of functional TLR4 confers proinflammatory responsiveness to Trypanosoma cruzi glycoinositolphospholipids and higher resistance to infection with T. cruzi. J Immunol 2004;173:5688-5696. (Pubitemid 39392157)
-
(2004)
Journal of Immunology
, vol.173
, Issue.9
, pp. 5688-5696
-
-
Oliveira, A.-C.1
Peixoto, J.R.2
De Arrada, L.B.3
Campos, M.A.4
Gazzinelli, R.T.5
Golenbock, D.T.6
Akira, S.7
Previato, J.O.8
Mendonca-Previato, L.9
Nobrega, A.10
Bellio, M.11
-
106
-
-
84861964067
-
Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children
-
Esposito S, Molteni CG, Zampiero A, et al. Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children. Malar J 2012;11: 196.
-
(2012)
Malar J
, vol.11
, pp. 196
-
-
Esposito, S.1
Molteni, C.G.2
Zampiero, A.3
-
107
-
-
84886951361
-
Polymorphisms and expression of TLR4 and 9 inmalaria in two ethnic groups of Assam, northeast India
-
Sawian CE, Lourembam SD, Banerjee A, Baruah S. Polymorphisms and expression of TLR4 and 9 inmalaria in two ethnic groups of Assam, northeast India. Innate Immun 2012.
-
(2012)
Innate Immun
-
-
Sawian, C.E.1
Lourembam, S.D.2
Banerjee, A.3
Baruah, S.4
-
108
-
-
79953256938
-
Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranianmalaria patients
-
Zakeri S, Pirahmadi S,Mehrizi AA, Djadid ND. Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranianmalaria patients.Malar J 2011;10:77.
-
(2011)
Malar J
, vol.10
, pp. 77
-
-
Zakeri, S.1
Pirahmadi, S.2
Mehrizi, A.A.3
Djadid, N.D.4
-
109
-
-
30444459750
-
Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria
-
DOI 10.1073/pnas.0506803102
-
Mockenhaupt FP, Cramer JP, Hamann L, et al. Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria. Proc Natl Acad Sci USA 2006;103:177-182. (Pubitemid 43076124)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.1
, pp. 177-182
-
-
Mockenhaupt, F.P.1
Cramer, J.P.2
Hamann, L.3
Stegemann, M.S.4
Eckert, J.5
Oh, N.-R.6
Otchwemah, R.N.7
Dietz, E.8
Ehrhardt, S.9
Schroder, N.W.J.10
Bienzle, U.11
Schumann, R.R.12
-
110
-
-
84856985660
-
Mannose-binding lectin and Toll-like receptor polymorphisms and Chagas disease in Chile
-
Weitzel T, Zulantay I, Danquah I, et al. Mannose-binding lectin and Toll-like receptor polymorphisms and Chagas disease in Chile. AmJ TropMed Hyg 2012;86:229-232.
-
(2012)
AmJ TropMed Hyg
, vol.86
, pp. 229-232
-
-
Weitzel, T.1
Zulantay, I.2
Danquah, I.3
-
111
-
-
84855281875
-
A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators
-
Broen JC, Bossini-Castillo L, van Bon L, et al. A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators. Arthritis Rheum 2012;64:264-271.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 264-271
-
-
Broen, J.C.1
Bossini-Castillo, L.2
Van Bon, L.3
-
112
-
-
84863760911
-
Associations between TLR polymorphisms and systemic lupus erythematosus: A systematic review and meta-analysis
-
Lee YH, Lee HS, Choi SJ, et al. Associations between TLR polymorphisms and systemic lupus erythematosus: a systematic review and meta-analysis. Clin Exp Rheumatol 2012;30:262-265.
-
(2012)
Clin Exp Rheumatol
, vol.30
, pp. 262-265
-
-
Lee, Y.H.1
Lee, H.S.2
Choi, S.J.3
-
113
-
-
79952461669
-
TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: A case-control association study
-
Kawasaki A, Furukawa H, Kondo Y, et al. TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study. Arthritis ResTher 2011;13:R41.
-
(2011)
Arthritis ResTher
, vol.13
-
-
Kawasaki, A.1
Furukawa, H.2
Kondo, Y.3
-
114
-
-
77957673544
-
Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus
-
Shen N, Fu Q, Deng Y, et al. Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus. Proc Natl Acad Sci USA 2010;107:15838-15843.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15838-15843
-
-
Shen, N.1
Fu, Q.2
Deng, Y.3
-
115
-
-
77950243833
-
Multiple common variants for celiac disease influencing immune gene expression
-
Dubois PC, Trynka G, Franke L, et al.Multiple common variants for celiac disease influencing immune gene expression. Nat Genet 2010;42:295-302.
-
(2010)
Nat Genet
, vol.42
, pp. 295-302
-
-
Dubois, P.C.1
Trynka, G.2
Franke, L.3
-
116
-
-
82555189795
-
Association of Toll-like receptor 10 and susceptibility to Crohn's disease independent of NOD2
-
Abad C, Gonzalez-Escribano MF, Diaz-Gallo LM, et al. Association of Toll-like receptor 10 and susceptibility to Crohn's disease independent of NOD2. Genes Immun 2011;12:635-642.
-
(2011)
Genes Immun
, vol.12
, pp. 635-642
-
-
Abad, C.1
Gonzalez-Escribano, M.F.2
Diaz-Gallo, L.M.3
-
117
-
-
84859108570
-
Genetic variation within TLR10 is associated with Crohn's disease in a New Zealand population
-
Morgan AR, Lam WJ, Han DY, et al. Genetic variation within TLR10 is associated with Crohn's disease in a New Zealand population. HumImmunol 2012;73:416-420.
-
(2012)
HumImmunol
, vol.73
, pp. 416-420
-
-
Morgan, A.R.1
Lam, W.J.2
Han, D.Y.3
-
118
-
-
83455200023
-
Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) influences disease course in sarcoidosis
-
Veltkamp M, van Moorsel CH, Rijkers GT, et al. Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) influences disease course in sarcoidosis. Tissue Antigens 2012;79: 25-32.
-
(2012)
Tissue Antigens
, vol.79
, pp. 25-32
-
-
Veltkamp, M.1
Van Moorsel, C.H.2
Rijkers, G.T.3
-
119
-
-
80054121511
-
Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk
-
Kutikhin AG. Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk. Hum Immunol 2011;72:1095-1116.
-
(2011)
Hum Immunol
, vol.72
, pp. 1095-1116
-
-
Kutikhin, A.G.1
-
120
-
-
4444279410
-
TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples
-
DOI 10.1164/rccm.200404-491OC
-
Lazarus R, Raby BA, Lange C, et al. TOLL-like receptor 10 genetic variation is associatedwith asthma in two independent samples. Am J Respir Crit CareMed 2004;170:594-600. (Pubitemid 39202199)
-
(2004)
American Journal of Respiratory and Critical Care Medicine
, vol.170
, Issue.6
, pp. 594-600
-
-
Lazarus, R.1
Raby, B.A.2
Lange, C.3
Silverman, E.K.4
Kwiatkowski, D.J.5
Vercelli, D.6
Klimecki, W.J.7
Martinez, F.D.8
Weiss, S.T.9
-
121
-
-
78049431319
-
Polymorphisms in the toll-like receptor 2 subfamily and risk of asthma: A case-control analysis in a Chinese population
-
Qian FH, Zhang Q, Zhou LF, et al. Polymorphisms in the toll-like receptor 2 subfamily and risk of asthma: a case-control analysis in a Chinese population. J Investig Allergol Clin Immunol 2010;20:340-346.
-
(2010)
J Investig Allergol Clin Immunol
, vol.20
, pp. 340-346
-
-
Qian, F.H.1
Zhang, Q.2
Zhou, L.F.3
-
122
-
-
1542721504
-
Toll-like receptor 2 as a major gene for asthma in children of European farmers
-
DOI 10.1016/j.jaci.2003.12.374
-
Eder W, Klimecki W, Yu L, et al. Toll-like receptor 2 as amajor gene for asthma in children of European farmers. J Allergy Clin Immunol 2004;113:482-488. (Pubitemid 38338954)
-
(2004)
Journal of Allergy and Clinical Immunology
, vol.113
, Issue.3
, pp. 482-488
-
-
Eder, W.1
Klimecki, W.2
Yu, L.3
Von Mutius, E.4
Riedler, J.5
Braun-Fahrlander, C.6
Nowak, D.7
Martinez, F.D.8
-
123
-
-
46049084570
-
Toll-like receptor heterodimer variants protect from childhood asthma
-
92 e81-88
-
Kormann MS, Depner M, Hartl D, et al. Toll-like receptor heterodimer variants protect from childhood asthma. J Allergy Clin Immunol 2008;122:86-92, 92 e81-88.
-
(2008)
J Allergy Clin Immunol
, vol.122
, pp. 86-92
-
-
Kormann, M.S.1
Depner, M.2
Hartl, D.3
-
124
-
-
84863875150
-
Toll-like receptors gene polymorphismsmay confer increased susceptibility to breast cancer development
-
Theodoropoulos GE, Saridakis V, Karantanos T, et al. Toll-like receptors gene polymorphismsmay confer increased susceptibility to breast cancer development. Breast 2012;21:534-538.
-
(2012)
Breast
, vol.21
, pp. 534-538
-
-
Theodoropoulos, G.E.1
Saridakis, V.2
Karantanos, T.3
-
125
-
-
84856573895
-
The association between Toll-like receptor 2 single-nucleotide polymorphisms and hepatocellular carcinoma susceptibility
-
Junjie X, Songyao J,Minmin S, et al. The association between Toll-like receptor 2 single-nucleotide polymorphisms and hepatocellular carcinoma susceptibility. BMC Cancer 2012;12:57.
-
(2012)
BMC Cancer
, vol.12
, pp. 57
-
-
Junjie, X.1
Songyao Jminmin, S.2
-
126
-
-
37049010741
-
Genetic polymorphisms of TLR3 are associated with Nasopharyngeal carcinoma risk in Cantonese population
-
He JF, Jia WH, Fan Q, et al. Genetic polymorphisms of TLR3 are associated with Nasopharyngeal carcinoma risk in Cantonese population. BMC Cancer 2007;7:194.
-
(2007)
BMC Cancer
, vol.7
, pp. 194
-
-
He, J.F.1
Jia, W.H.2
Fan, Q.3
-
127
-
-
84862801106
-
Cytokine and chemokine modification by Toll-like receptor polymorphisms is associated with nasopharyngeal carcinoma
-
Yang ZH, Dai Q, Gu YJ, et al. Cytokine and chemokine modification by Toll-like receptor polymorphisms is associated with nasopharyngeal carcinoma. Cancer Sci 2012;103:653-658.
-
(2012)
Cancer Sci
, vol.103
, pp. 653-658
-
-
Zh, Y.1
Dai, Q.2
Gu, Y.J.3
-
128
-
-
33751103416
-
Functional variant in the 3′-untranslated region of toll-like receptor 4 is associated with nasopharyngeal carcinoma risk
-
Song C, Chen LZ, Zhang RH, et al. Functional variant in the 3'-untranslated region of Toll-like receptor 4 is associated with nasopharyngeal carcinoma risk. Cancer Biol Ther 2006;5:1285-1291. (Pubitemid 44772253)
-
(2006)
Cancer Biology and Therapy
, vol.5
, Issue.10
, pp. 1285-1291
-
-
Song, C.1
Chen, L.-Z.2
Zhang, R.-H.3
Yu, X.-J.4
Zeng, Y.-X.5
-
129
-
-
80052566598
-
Association of inherited variation in Toll-like receptor genes with malignantmelanoma susceptibility and survival
-
Gast A, Bermejo JL, Claus R, et al. Association of inherited variation in Toll-like receptor genes with malignantmelanoma susceptibility and survival. PLoS One 2011;6:e24370.
-
(2011)
PLoS One
, vol.6
-
-
Gast, A.1
Bermejo, J.L.2
Claus, R.3
-
130
-
-
84862007483
-
Polymorphisms in the TLR6 gene associated with the inverse association between childhood acute lymphoblastic leukemia and atopic disease
-
Miedema KG, Tissing WJ, Te Poele EM, et al. Polymorphisms in the TLR6 gene associated with the inverse association between childhood acute lymphoblastic leukemia and atopic disease. Leukemia 2012;26:1203-1210.
-
(2012)
Leukemia
, vol.26
, pp. 1203-1210
-
-
Miedema, K.G.1
Tissing, W.J.2
Te Poele, E.M.3
-
131
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
DOI 10.1038/nri2079, PII NRI2079
-
O'Neill LA, Bowie AG.Thefamily of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 2007;7:353-364. (Pubitemid 46674493)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.5
, pp. 353-364
-
-
O'Neill, L.A.J.1
Bowie, A.G.2
-
132
-
-
16644368119
-
Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses
-
DOI 10.1016/j.micinf.2004.08.017
-
Beutler B, Hoebe K, Georgel P, et al. Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses.Microbes Infect 2004;6:1374-1381. (Pubitemid 41110580)
-
(2004)
Microbes and Infection
, vol.6
, Issue.15
, pp. 1374-1381
-
-
Beutler, B.1
Hoebe, K.2
Georgel, P.3
Tabeta, K.4
Du, X.5
-
133
-
-
55149105005
-
The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress
-
O'Neill LA. The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol Rev 2008;226:10-18.
-
(2008)
Immunol Rev
, vol.226
, pp. 10-18
-
-
O'Neill, L.A.1
-
134
-
-
51349158231
-
Signalling adaptors used by Toll-like receptors: An update
-
Kenny EF, O'Neill LA. Signalling adaptors used by Toll-like receptors: an update. Cytokine 2008;43:342-349.
-
(2008)
Cytokine
, vol.43
, pp. 342-349
-
-
Kenny, E.F.1
O'Neill, L.A.2
-
135
-
-
33748871187
-
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
-
DOI 10.1038/ni1382, PII NI1382
-
Carty M, Goodbody R, Schroder M, et al. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat Immunol 2006;7:1074-1081. (Pubitemid 44420652)
-
(2006)
Nature Immunology
, vol.7
, Issue.10
, pp. 1074-1081
-
-
Carty, M.1
Goodbody, R.2
Schroder, M.3
Stack, J.4
Moynagh, P.N.5
Bowie, A.G.6
-
136
-
-
77953315434
-
SARM inhibits both TRIF-andMyD88-mediated AP-1 activation
-
Peng J, Yuan Q, Lin B, et al. SARM inhibits both TRIF-andMyD88-mediated AP-1 activation. Eur J Immunol 2010;40:1738-1747.
-
(2010)
Eur J Immunol
, vol.40
, pp. 1738-1747
-
-
Peng, J.1
Yuan, Q.2
Lin, B.3
-
137
-
-
84866528957
-
Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways
-
Murray PJ, Smale ST. Restraint of inflammatory signaling by interdependent strata of negative regulatory pathways. Nat Immunol 2012;13:916-924.
-
(2012)
Nat Immunol
, vol.13
, pp. 916-924
-
-
Murray, P.J.1
Smale, S.T.2
-
138
-
-
55349142293
-
IRAK-4-and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans
-
Isnardi I, Ng YS, Srdanovic I, et al. IRAK-4-and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. Immunity 2008;29:746-757.
-
(2008)
Immunity
, vol.29
, pp. 746-757
-
-
Isnardi, I.1
Ng, Y.S.2
Srdanovic, I.3
-
139
-
-
82555187209
-
UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling
-
Itoh H, TatematsuM,Watanabe A, et al. UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling. PLoS One 2011;6:e28500.
-
(2011)
PLoS One
, vol.6
-
-
Itoh, H.1
Tatematsu, M.2
Watanabe, A.3
-
140
-
-
84864817250
-
Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis
-
Shah JA, Vary JC, Chau TT, et al. Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis. J Immunol 2012;189:1737-1746.
-
(2012)
J Immunol
, vol.189
, pp. 1737-1746
-
-
Shah, J.A.1
Vary, J.C.2
Chau, T.T.3
-
141
-
-
79960121968
-
Infectious diseases in patients with IRAK-4,MyD88, NEMO, or IkappaBalpha deficiency
-
Picard C, Casanova JL, Puel A. Infectious diseases in patients with IRAK-4,MyD88, NEMO, or IkappaBalpha deficiency. ClinMicrobiol Rev 2011;24:490-497.
-
(2011)
ClinMicrobiol Rev
, vol.24
, pp. 490-497
-
-
Picard, C.1
Casanova, J.L.2
Puel, A.3
-
142
-
-
48749109290
-
Pyogenic bacterial infections in humans with MyD88 deficiency
-
von Bernuth H, Picard C, Jin Z, et al. Pyogenic bacterial infections in humans with MyD88 deficiency. Science 2008;321:691-696.
-
(2008)
Science
, vol.321
, pp. 691-696
-
-
Von Bernuth, H.1
Picard, C.2
Jin, Z.3
-
143
-
-
0037471003
-
Pyogenic bacterial infections in humans with IRAK-4 deficiency
-
DOI 10.1126/science.1081902
-
Picard C, Puel A, BonnetM, et al. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 2003;299:2076-2079. (Pubitemid 36383736)
-
(2003)
Science
, vol.299
, Issue.5615
, pp. 2076-2079
-
-
Picard, C.1
Puel, A.2
Bonnet, M.3
Ku, C.-L.4
Bustamante, J.5
Yang, K.6
Soudais, C.7
Dupuis, S.8
Feinberg, J.9
Fieschi, C.10
Elbim, C.11
Hitchcock, R.12
Lammas, D.13
Davies, G.14
Al-Ghonaium, A.15
Al-Rayes, H.16
Al-Jumaah, S.17
Al-Hajjar, S.18
Al-Mohsen, I.Z.19
Frayha, H.H.20
Rucker, R.21
Hawn, T.R.22
Aderem, A.23
Tufenkeji, H.24
Haraguchi, S.25
Day, N.K.26
Good, R.A.27
Gougerot-Pocidalo, M.-A.28
Ozinsky, A.29
Casanova, J.-L.30
more..
-
144
-
-
34948904198
-
Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity
-
DOI 10.1084/jem.20070628
-
Ku CL, von Bernuth H, Picard C, et al. Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med 2007;204:2407-2422. (Pubitemid 47529326)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.10
, pp. 2407-2422
-
-
Ku, C.-L.1
Von Bernuth, H.2
Picard, C.3
Zhang, S.-Y.4
Chang, H.-H.5
Yang, K.6
Chrabieh, M.7
Issekutz, A.C.8
Cunningham, C.K.9
Gallin, J.10
Holland, S.M.11
Roifman, C.12
Ehl, S.13
Smart, J.14
Tang, M.15
Barrat, F.J.16
Levy, O.17
McDonald, D.18
Day-Good, N.K.19
Miller, R.20
Takada, H.21
Hara, T.22
Al-Hajjar, S.23
Al-Ghonaium, A.24
Speert, D.25
Sanlaville, D.26
Li, X.27
Geissmann, F.28
Vivier, E.29
Marodi, L.30
Garty, B.-Z.31
Chapel, H.32
Rodriguez-Gallego, C.33
Bossuyt, X.34
Abel, L.35
Puel, A.36
Casanova, J.-L.37
more..
-
145
-
-
77957018085
-
Human TRAF3 adaptormolecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis
-
Perez de Diego R, Sancho-Shimizu V, Lorenzo L, et al. Human TRAF3 adaptormolecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis. Immunity 2010;33:400-411.
-
(2010)
Immunity
, vol.33
, pp. 400-411
-
-
Perez De Diego, R.1
Sancho-Shimizu, V.2
Lorenzo, L.3
-
146
-
-
84866393226
-
Heterozygous TBK1mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood
-
Herman M, Ciancanelli M, Ou YH, et al. Heterozygous TBK1mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood. J ExpMed 2012;209:1567-1582.
-
(2012)
J ExpMed
, vol.209
, pp. 1567-1582
-
-
Herman, M.1
Ciancanelli, M.2
Ou, Y.H.3
-
147
-
-
84055190795
-
Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency
-
Sancho-Shimizu V, Perez deDiego R, Lorenzo L, et al.Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency. J Clin Invest 2011;121:4889-4902.
-
(2011)
J Clin Invest
, vol.121
, pp. 4889-4902
-
-
Sancho-Shimizu, V.1
Perez Dediego, R.2
Lorenzo, L.3
-
148
-
-
84870292016
-
Impaired intrinsic immunity to HSV-1 in human iPSCderived TLR3-deficient CNS cells
-
Lafaille FG, Pessach IM, Zhang SY, et al. Impaired intrinsic immunity to HSV-1 in human iPSCderived TLR3-deficient CNS cells. Nature 2012;491:769-773.
-
(2012)
Nature
, vol.491
, pp. 769-773
-
-
Lafaille, F.G.1
Pessach, I.M.2
Zhang, S.Y.3
-
149
-
-
33750016788
-
Herpes simplex virus encephalitis in human UNC-93B deficiency
-
DOI 10.1126/science.1128346
-
Casrouge A, Zhang SY, Eidenschenk C, et al. Herpes simplex virus encephalitis in human UNC-93B deficiency. Science 2006;314:308-312. (Pubitemid 44571977)
-
(2006)
Science
, vol.314
, Issue.5797
, pp. 308-312
-
-
Casrouge, A.1
Zhang, S.-Y.2
Eidenschenk, C.3
Jouanguy, E.4
Puel, A.5
Yang, K.6
Alcais, A.7
Picard, C.8
Mahfoufi, N.9
Nicolas, N.10
Lorenzo, L.11
Plancoulaine, S.12
Senechal, B.13
Geissmann, F.14
Tabeta, K.15
Hoebe, K.16
Du, X.17
Miller, R.L.18
Heron, B.19
Mignot, C.20
Billette De Villemeur, T.21
Lebon, P.22
Dulac, O.23
Rozenberg, F.24
Beutler, B.25
Tardieu, M.26
Abel, L.27
Casanova, J.-L.28
more..
-
150
-
-
34047098731
-
A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis
-
DOI 10.1038/ng1976, PII NG1976
-
Khor CC, Chapman SJ, Vannberg FO, et al. A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. Nat Genet 2007;39:523-528. (Pubitemid 46514767)
-
(2007)
Nature Genetics
, vol.39
, Issue.4
, pp. 523-528
-
-
Khor, C.C.1
Chapman, S.J.2
Vannberg, F.O.3
Dunne, A.4
Murphy, C.5
Ling, E.Y.6
Frodsham, A.J.7
Walley, A.J.8
Kyrieleis, O.9
Khan, A.10
Aucan, C.11
Segal, S.12
Moore, C.E.13
Knox, K.14
Campbell, S.J.15
Lienhardt, C.16
Scott, A.17
Aaby, P.18
Sow, O.Y.19
Grignani, R.T.20
Sillah, J.21
Sirugo, G.22
Peshu, N.23
Williams, T.N.24
Maitland, K.25
Davies, R.J.O.26
Kwiatkowski, D.P.27
Day, N.P.28
Yala, D.29
Crook, D.W.30
Marsh, K.31
Berkley, J.A.32
O'Neill, L.A.J.33
Hill, A.V.S.34
more..
-
151
-
-
67849135834
-
Lowfrequency of the TIRAP S180L polymorphism in Africa, and its potential role inmalaria, sepsis, and leprosy
-
Hamann L,KumpfO, Schuring RP, et al. Lowfrequency of the TIRAP S180L polymorphism in Africa, and its potential role inmalaria, sepsis, and leprosy. BMCMed Genet 2009;10:65.
-
(2009)
BMCMed Genet
, vol.10
, pp. 65
-
-
Hamann, L.1
Kumpf, O.2
Schuring, R.P.3
-
152
-
-
39749190644
-
Analysis of association of the TIRAP (MAL) S180L variant and tuberculosis in three populations
-
DOI 10.1038/ng0308-261, PII NG0308261
-
Nejentsev S,Thye T, Szeszko JS, et al. Analysis of association of the TIRAP (MAL) S180L variant and tuberculosis in three populations. Nat Genet 2008;40:261-262; author reply 262-263. (Pubitemid 351311779)
-
(2008)
Nature Genetics
, vol.40
, Issue.3
, pp. 261-262
-
-
Nejentsev, S.1
Thye, T.2
Szeszko, J.S.3
Stevens, H.4
Balabanova, Y.5
Chinbuah, A.M.6
Hibberd, M.7
Van De Vosse, E.8
Alisjahbana, B.9
Van Crevel, R.10
Ottenhoff, T.H.M.11
Png, E.12
Drobniewski, F.13
Todd, J.A.14
Seielstad, M.15
Horstmann, R.D.16
-
153
-
-
84861583442
-
Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo
-
Jin Y, Birlea SA, Fain PR, et al. Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. Nat Genet 2012;44:676-680.
-
(2012)
Nat Genet
, vol.44
, pp. 676-680
-
-
Jin, Y.1
Birlea, S.A.2
Fain, P.R.3
-
154
-
-
29144452851
-
The C-type lectin-like domain superfamily
-
DOI 10.1111/j.1742-4658.2005.05031.x
-
Zelensky AN, Gready JE. The C-type lectin-like domain superfamily. FEBS J 2005;272:6179-6217. (Pubitemid 41815610)
-
(2005)
FEBS Journal
, vol.272
, Issue.24
, pp. 6179-6217
-
-
Zelensky, A.N.1
Gready, J.E.2
-
155
-
-
0029952519
-
Structural basis of lectin-carbohydrate recognition
-
Weis WI, Drickamer K. Structural basis of lectin-carbohydrate recognition. Annu Rev Biochem 1996;65:441-473. (Pubitemid 26250616)
-
(1996)
Annual Review of Biochemistry
, vol.65
, pp. 441-473
-
-
Weis, W.I.1
Drickamer, K.2
-
156
-
-
84857175933
-
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome
-
Gringhuis SI, Kaptein TM, Wevers BA, et al. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome. Nat Immunol 2012;13:246-254.
-
(2012)
Nat Immunol
, vol.13
, pp. 246-254
-
-
Gringhuis, S.I.1
Kaptein, T.M.2
Wevers, B.A.3
-
157
-
-
70350534272
-
Human dectin-1 deficiency andmucocutaneous fungal infections
-
Ferwerda B, Ferwerda G, Plantinga TS, et al.Human dectin-1 deficiency andmucocutaneous fungal infections. N Engl JMed 2009;361:1760-1767.
-
(2009)
N Engl JMed
, vol.361
, pp. 1760-1767
-
-
Ferwerda, B.1
Ferwerda, G.2
Plantinga, T.S.3
-
158
-
-
70350545720
-
A homozygous CARD9mutation in a family with susceptibility to fungal infections
-
Glocker EO, Hennigs A, Nabavi M, et al. A homozygous CARD9mutation in a family with susceptibility to fungal infections. N Engl JMed 2009;361:1727-1735.
-
(2009)
N Engl JMed
, vol.361
, pp. 1727-1735
-
-
Glocker, E.O.1
Hennigs, A.2
Nabavi, M.3
-
159
-
-
33846307747
-
Myeloid C-type lectins in innate immunity
-
DOI 10.1038/ni1417, PII NI1417
-
Robinson MJ, Sancho D, Slack EC, et al. Myeloid C-type lectins in innate immunity. Nat Immunol 2006;7:1258-1265. (Pubitemid 46111243)
-
(2006)
Nature Immunology
, vol.7
, Issue.12
, pp. 1258-1265
-
-
Robinson, M.J.1
Sancho, D.2
Slack, E.C.3
LeibundGut-Landmann, S.4
Sousa, C.R.5
-
160
-
-
84860228172
-
An evolutionary perspective on C-type lectins in infection and immunity
-
van den Berg LM, Gringhuis SI, Geijtenbeek TB. An evolutionary perspective on C-type lectins in infection and immunity. Ann NY Acad Sci 2012;1253:149-158.
-
(2012)
Ann NY Acad Sci
, vol.1253
, pp. 149-158
-
-
Van Den Berg, L.M.1
Gringhuis, S.I.2
Geijtenbeek, T.B.3
-
161
-
-
84871321329
-
Inborn errors of human IL-17 immunity underlie chronicmucocutaneous candidiasis
-
Puel A, Cypowyj S,Marodi L, et al. Inborn errors of human IL-17 immunity underlie chronicmucocutaneous candidiasis. Curr Opin Allergy Clin Immunol 2012;12:616-622.
-
(2012)
Curr Opin Allergy Clin Immunol
, vol.12
, pp. 616-622
-
-
Puel, A.1
Cypowyj, S.2
Marodi, L.3
-
162
-
-
78650464495
-
The Y238X stop codon polymorphism in the human beta-glucan receptor dectin-1 and susceptibility to invasive aspergillosis
-
Chai LY, de Boer MG, van der Velden WJ, et al. The Y238X stop codon polymorphism in the human beta-glucan receptor dectin-1 and susceptibility to invasive aspergillosis. J Infect Dis 2011;203:736-743.
-
(2011)
J Infect Dis
, vol.203
, pp. 736-743
-
-
Chai, L.Y.1
De Boer, M.G.2
Van Der Velden, W.J.3
-
163
-
-
77958450338
-
Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient-and donor-dependent mechanisms of antifungal immunity
-
Cunha C, Di Ianni M, Bozza S, et al. Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient-and donor-dependent mechanisms of antifungal immunity. Blood 2010;116:5394-5402.
-
(2010)
Blood
, vol.116
, pp. 5394-5402
-
-
Cunha, C.1
Di Ianni, M.2
Bozza, S.3
-
164
-
-
69949109204
-
Early stop polymorphism in human DECTIN-1 is associated with increased candida colonization in hematopoietic stem cell transplant recipients
-
Plantinga TS, van der Velden WJ, Ferwerda B, et al. Early stop polymorphism in human DECTIN-1 is associated with increased candida colonization in hematopoietic stem cell transplant recipients. Clin Infect Dis 2009;49:724-732.
-
(2009)
Clin Infect Dis
, vol.49
, pp. 724-732
-
-
Plantinga, T.S.1
Van Der Velden, W.J.2
Ferwerda, B.3
-
165
-
-
33644836015
-
Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis
-
Barreiro LB, Neyrolles O, Babb CL, et al. Promoter variation in the DC-SIGN-encoding gene CD209 is associated with tuberculosis. PLoSMed 2006;3:e20.
-
(2006)
PLoSMed
, vol.3
-
-
Barreiro, L.B.1
Neyrolles, O.2
Babb, C.L.3
-
166
-
-
20944450979
-
A variant in the CD209 promoter is associated with severity of dengue disease
-
DOI 10.1038/ng1550
-
Sakuntabhai A, Turbpaiboon C, Casademont I, et al. A variant in the CD209 promoter is associated with severity of dengue disease. Nat Genet 2005;37:507-513. (Pubitemid 40617279)
-
(2005)
Nature Genetics
, vol.37
, Issue.5
, pp. 507-513
-
-
Sakuntabhai, A.1
Turbpaiboon, C.2
Casademont, I.3
Chuansumrit, A.4
Lowhnoo, T.5
Kajaste-Rudnitski, A.6
Kalayanarooj, S.M.7
Tangnararatchakit, K.8
Tangthawornchaikul, N.9
Vasanawathana, S.10
Chaiyaratana, W.11
Yenchitsomanus, P.-T.12
Suriyaphol, P.13
Avirutnan, P.14
Chokephaibulkit, K.15
Matsuda, F.16
Yoksan, S.17
Jacob, Y.18
Lathrop, G.M.19
Malasit, P.20
Despres, P.21
Julier, C.22
more..
-
167
-
-
10044246336
-
Association of DC-SIGN promoter polymorphism with increased risk for parenteral, but not mucosal, acquisition of human immunodeficiency virus type 1 infection
-
DOI 10.1128/JVI.78.24.14053-14056.2004
-
Martin MP, Lederman MM,HutchesonHB, et al. Association ofDC-SIGN promoter polymorphism with increased risk for parenteral, but notmucosal, acquisition of human immunodeficiency virus type 1 infection. J Virol 2004;78:14053-14056. (Pubitemid 39612803)
-
(2004)
Journal of Virology
, vol.78
, Issue.24
, pp. 14053-14056
-
-
Martin, M.P.1
Lederman, M.M.2
Hutcheson, H.B.3
Goedert, J.J.4
Nelson, G.W.5
Van Kooyk, Y.6
Detels, R.7
Buchbinder, S.8
Hoots, K.9
Vlahov, D.10
O'Brien, S.J.11
Carrington, M.12
-
168
-
-
38849171139
-
CD209 genetic polymorphism and tuberculosis disease
-
Vannberg FO, Chapman SJ, Khor CC, et al. CD209 genetic polymorphism and tuberculosis disease. PLoS One 2008;3:e1388.
-
(2008)
PLoS One
, vol.3
-
-
Vannberg, F.O.1
Chapman, S.J.2
Khor, C.C.3
-
169
-
-
80051684615
-
Genetic risk and a primary role for cell-mediated immune mechanisms inmultiple sclerosis
-
Sawcer S, Hellenthal G, Pirinen M, et al. Genetic risk and a primary role for cell-mediated immune mechanisms inmultiple sclerosis. Nature 2011;476:214-219.
-
(2011)
Nature
, vol.476
, pp. 214-219
-
-
Sawcer, S.1
Hellenthal, G.2
Pirinen, M.3
-
170
-
-
34247627809
-
Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation
-
DOI 10.1126/science.1137971
-
Burgdorf S, Kautz A, Bohnert V, et al. Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation. Science 2007;316:612-616. (Pubitemid 46683149)
-
(2007)
Science
, vol.316
, Issue.5824
, pp. 612-616
-
-
Burgdorf, S.1
Kautz, A.2
Bohnert, V.3
Knolle, P.A.4
Kurts, C.5
-
171
-
-
0021363812
-
Carbohydrate-specific adhesion of alveolar macrophages to mannose-derivatized surfaces
-
Largent BL,Walton KM, Hoppe CA, et al. Carbohydrate-specific adhesion of alveolarmacrophages tomannose-derivatized surfaces. J Biol Chem 1984;259:1764-1769. (Pubitemid 14146564)
-
(1984)
Journal of Biological Chemistry
, vol.259
, Issue.3
, pp. 1764-1769
-
-
Largent, B.L.1
Walton, K.M.2
Hoppe, C.A.3
-
172
-
-
10744233727
-
Cross-Linking of the Mannose Receptor on Monocyte-Derived Dendritic Cells Activates an Anti-Inflammatory Immunosuppressive Program
-
Chieppa M, Bianchi G, Doni A, et al. Cross-linking of the mannose receptor on monocytederived dendritic cells activates an anti-inflammatory immunosuppressive program. J Immunol 2003;171:4552-4560. (Pubitemid 37310570)
-
(2003)
Journal of Immunology
, vol.171
, Issue.9
, pp. 4552-4560
-
-
Chieppa, M.1
Bianchi, G.2
Doni, A.3
Del Prete, A.4
Sironi, M.5
Laskarin, G.6
Monti, P.7
Piemonti, L.8
Biondi, A.9
Mantovani, A.10
Introna, M.11
Allavena, P.12
-
173
-
-
77951859065
-
Mannose receptor interacts with Fc receptors and is critical for the development of crescentic glomerulonephritis in mice
-
Chavele KM, Martinez-Pomares L, Domin J, et al. Mannose receptor interacts with Fc receptors and is critical for the development of crescentic glomerulonephritis in mice. J Clin Invest 2010;120:1469-1478.
-
(2010)
J Clin Invest
, vol.120
, pp. 1469-1478
-
-
Chavele, K.M.1
Martinez-Pomares, L.2
Domin, J.3
-
174
-
-
24744434381
-
Negative regulatory role of mannose receptors on human alveolar macrophage proinflammatory cytokine release in vitro
-
DOI 10.1189/jlb.1204699
-
Zhang J, Tachado SD, Patel N, et al. Negative regulatory role ofmannose receptors on human alveolarmacrophage proinflammatory cytokine release in vitro. J Leukoc Biol 2005;78:665-674. (Pubitemid 41292089)
-
(2005)
Journal of Leukocyte Biology
, vol.78
, Issue.3
, pp. 665-674
-
-
Zhang, J.1
Tachado, S.D.2
Patel, N.3
Zhu, J.4
Imrich, A.5
Manfruelli, P.6
Cushion, M.7
Kinane, T.B.8
Koziel, H.9
-
175
-
-
77956405332
-
Themannose receptor mediates the uptake of diverse native allergens by dendritic cells and determines allergen-induced T cell polarization through modulation of IDO activity
-
Royer PJ, EmaraM, Yang C, et al.Themannose receptor mediates the uptake of diverse native allergens by dendritic cells and determines allergen-induced T cell polarization through modulation of IDO activity. J Immunol 2010;185:1522-1531.
-
(2010)
J Immunol
, vol.185
, pp. 1522-1531
-
-
Royer, P.J.1
Emara, M.2
Yang, C.3
-
176
-
-
77649184039
-
Genome-wide association study of hematological and biochemical traits in a Japanese population
-
Kamatani Y,Matsuda K, Okada Y, et al. Genome-wide association study of hematological and biochemical traits in a Japanese population. Nat Genet 2010;42:210-215.
-
(2010)
Nat Genet
, vol.42
, pp. 210-215
-
-
Kamatani, Y.1
Matsuda, K.2
Okada, Y.3
-
177
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
DOI 10.1038/ng2068, PII NG2068
-
Todd JA, Walker NM, Cooper JD, et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 2007;39:857-864. (Pubitemid 47018195)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
Smyth, D.J.4
Downes, K.5
Plagnol, V.6
Bailey, R.7
Nejentsev, S.8
Field, S.F.9
Payne, F.10
Lowe, C.E.11
Szeszko, J.S.12
Hafler, J.P.13
Zeitels, L.14
Yang, J.H.M.15
Vella, A.16
Nutland, S.17
Stevens, H.E.18
Schuilenburg, H.19
Coleman, G.20
Maisuria, M.21
Meadows, W.22
Smink, L.J.23
Healy, B.24
Burren, O.S.25
Lam, A.A.C.26
Ovington, N.R.27
Allen, J.28
Adlem, E.29
Leung, H.-T.30
Wallace, C.31
Howson, J.M.M.32
Guja, C.33
Ionescu-Tirgoviste, C.34
Simmonds, M.J.35
Heward, J.M.36
Gough, S.C.L.37
Dunger, D.B.38
Wicker, L.S.39
Clayton, D.G.40
more..
-
178
-
-
84856275511
-
Involvement of CLEC16A in activation of astrocytes after LPS treated
-
Wu X, Li J, Chen C, et al. Involvement of CLEC16A in activation of astrocytes after LPS treated. Neurochem Res 2012;37:5-14.
-
(2012)
Neurochem Res
, vol.37
, pp. 5-14
-
-
Wu, X.1
Li, J.2
Chen, C.3
-
179
-
-
77949361027
-
The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation
-
Kim S, Wairkar YP, Daniels RW, DiAntonio A. The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation. J Cell Biol 2010;188:717-734.
-
(2010)
J Cell Biol
, vol.188
, pp. 717-734
-
-
Kim, S.1
Wairkar, Y.P.2
Daniels, R.W.3
Diantonio, A.4
-
180
-
-
34547621758
-
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene
-
DOI 10.1038/nature06010, PII NATURE06010
-
Hakonarson H, Grant SF, Bradfield JP, et al. A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. Nature 2007;448:591-594. (Pubitemid 47206935)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 591-594
-
-
Hakonarson, H.1
Grant, S.F.A.2
Bradfield, J.P.3
Marchand, L.4
Kim, C.E.5
Glessner, J.T.6
Grabs, R.7
Casalunovo, T.8
Taback, S.P.9
Frackelton, E.C.10
Lawson, M.L.11
Robinson, L.J.12
Skraban, R.13
Lu, Y.14
Chiavacci, R.M.15
Stanley, C.A.16
Kirsch, S.E.17
Rappaport, E.F.18
Orange, J.S.19
Monos, D.S.20
Devoto, M.21
Qu, H.-Q.22
Polychronakos, C.23
more..
-
181
-
-
80055099134
-
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order
-
Ramasamy A, Curjuric I, Coin LJ, et al. A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order. J Allergy Clin Immunol 2011;128:996-1005.
-
(2011)
J Allergy Clin Immunol
, vol.128
, pp. 996-1005
-
-
Ramasamy, A.1
Curjuric, I.2
Coin, L.J.3
-
182
-
-
79953208931
-
Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis
-
Mells GF, Floyd JA,Morley KI, et al.Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. Nat Genet 2011;43:329-332.
-
(2011)
Nat Genet
, vol.43
, pp. 329-332
-
-
Mells, G.F.1
Floyd, J.A.2
Morley, K.I.3
-
183
-
-
80052311755
-
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases
-
Plagnol V, Howson JM, Smyth DJ, et al. Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genet 2011;7:e1002216.
-
(2011)
PLoS Genet
, vol.7
-
-
Plagnol, V.1
Howson, J.M.2
Smyth, D.J.3
-
184
-
-
56749183605
-
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
-
Cooper JD, Smyth DJ, Smiles AM, et al.Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Nat Genet 2008;40:1399-1401.
-
(2008)
Nat Genet
, vol.40
, pp. 1399-1401
-
-
Cooper, J.D.1
Smyth, D.J.2
Smiles, A.M.3
-
185
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as newmultiple sclerosis susceptibility loci
-
De Jager PL, Jia X, Wang J, et al.Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as newmultiple sclerosis susceptibility loci. Nat Genet 2009;41:776-782.
-
(2009)
Nat Genet
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
-
186
-
-
77955463306
-
A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis
-
Skinningsrud B, Lie BA, Husebye ES, et al. A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis. Ann Rheum Dis 2010;69:1471-1474.
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 1471-1474
-
-
Skinningsrud, B.1
Lie, B.A.2
Husebye, E.S.3
-
187
-
-
77349120714
-
Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activationmotifs
-
Kerrigan AM, Brown GD. Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activationmotifs. Immunol Rev 2010;234:335-352.
-
(2010)
Immunol Rev
, vol.234
, pp. 335-352
-
-
Kerrigan, A.M.1
Brown, G.D.2
-
188
-
-
84886949580
-
T cells: The MALT1 switch in autoimmunity
-
PapatriantafyllouM. T cells: the MALT1 switch in autoimmunity. Nat Rev Immunol 2012;12:807.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 807
-
-
Papatriantafyllou, M.1
-
189
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 2011;43:246-252.
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
-
190
-
-
78649489009
-
Genome-widemeta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A,McGovern DP, Barrett JC, et al. Genome-widemeta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010;42:1118-1125.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
-
191
-
-
77950298959
-
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
-
McGovern DP, Gardet A, Torkvist L, et al. Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet 2010;42:332-337.
-
(2010)
Nat Genet
, vol.42
, pp. 332-337
-
-
McGovern, D.P.1
Gardet, A.2
Torkvist, L.3
-
192
-
-
70649103789
-
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
-
Barrett JC, Lee JC, Lees CW, et al. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet 2009;41:1330-1334.
-
(2009)
Nat Genet
, vol.41
, pp. 1330-1334
-
-
Barrett, J.C.1
Lee, J.C.2
Lees, C.W.3
-
193
-
-
79960899377
-
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
-
Evans DM, Spencer CC, Pointon JJ, et al. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet 2011;43:761-767.
-
(2011)
Nat Genet
, vol.43
, pp. 761-767
-
-
Evans, D.M.1
Spencer, C.C.2
Pointon, J.J.3
-
194
-
-
84863503465
-
A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations
-
Imamura M, Maeda S, Yamauchi T, et al. A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Hum Mol Genet 2012;21: 3042-3049.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 3042-3049
-
-
Imamura, M.1
Maeda, S.2
Yamauchi, T.3
-
195
-
-
79951887844
-
Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk andmortality
-
Parsa A, Chang YP, Kelly RJ, et al.Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk andmortality. Clin Transl Sci 2011;4:17-23.
-
(2011)
Clin Transl Sci
, vol.4
, pp. 17-23
-
-
Parsa, A.1
Chang, Y.P.2
Kelly, R.J.3
-
196
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich TM,Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010;466:707-713.
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
-
197
-
-
78751620798
-
NLR functions beyond pathogen recognition
-
Kufer TA, Sansonetti PJ. NLR functions beyond pathogen recognition. Nat Immunol 2011;12:121-128.
-
(2011)
Nat Immunol
, vol.12
, pp. 121-128
-
-
Kufer, T.A.1
Sansonetti, P.J.2
-
200
-
-
77950626219
-
Nucleotide-binding oligomerizationdomain containing 2 (NOD2) variants are genetic risk factors for death and spontaneous bacterial peritonitis in liver cirrhosis
-
Appenrodt B, Grunhage F,GentemannMG, et al.Nucleotide-binding oligomerizationdomain containing 2 (NOD2) variants are genetic risk factors for death and spontaneous bacterial peritonitis in liver cirrhosis. Hepatology 2010;51:1327-1333.
-
(2010)
Hepatology
, vol.51
, pp. 1327-1333
-
-
Appenrodt, B.1
Grunhage, F.2
Gentemann, M.G.3
-
201
-
-
79956329100
-
Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associatedwith increased risk for spontaneous bacterial peritonitis inliver cirrhosis
-
Nischalke HD, Berger C, Aldenhoff K, et al. Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associatedwith increased risk for spontaneous bacterial peritonitis inliver cirrhosis. J Hepatol 2011;55:1010-1016.
-
(2011)
J Hepatol
, vol.55
, pp. 1010-1016
-
-
Nischalke, H.D.1
Berger, C.2
Aldenhoff, K.3
-
202
-
-
74049127960
-
Genomewide association study of leprosy
-
Zhang FR, Huang W, Chen SM, et al. Genomewide association study of leprosy. N Engl J Med 2009;361:2609-2618.
-
(2009)
N Engl J Med
, vol.361
, pp. 2609-2618
-
-
Zhang, F.R.1
Huang, W.2
Chen, S.M.3
-
203
-
-
77950954449
-
Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states
-
BerringtonWR,MacdonaldM, Khadge S, et al. Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states. J Infect Dis 2010;201:1422-1435.
-
(2010)
J Infect Dis
, vol.201
, pp. 1422-1435
-
-
Berrington, W.R.1
MacDonald, M.2
Khadge, S.3
-
204
-
-
84869037440
-
Crohn's disease susceptibility genes are associated with Leprosy in the Vietnamese population
-
Grant AV, Alter A,Huong NT, et al. Crohn's disease susceptibility genes are associated with Leprosy in the Vietnamese population. J Infect Dis 2012;206:1763-1767.
-
(2012)
J Infect Dis
, vol.206
, pp. 1763-1767
-
-
Grant, A.V.1
Alter, A.2
Huong, N.T.3
-
205
-
-
84862805230
-
NOD2 triggers an interleukin-32-dependent human dendritic cell programin leprosy
-
Schenk M, Krutzik SR, Sieling PA, et al. NOD2 triggers an interleukin-32-dependent human dendritic cell programin leprosy. NatMed 2012;18:555-563.
-
(2012)
NatMed
, vol.18
, pp. 555-563
-
-
Schenk, M.1
Krutzik, S.R.2
Sieling, P.A.3
-
206
-
-
79953219478
-
Genetic andmolecular basis of inflammasome-mediated disease
-
Hoffman HM, Brydges SD. Genetic andmolecular basis of inflammasome-mediated disease. J Biol Chem 2011;286:10889-10896.
-
(2011)
J Biol Chem
, vol.286
, pp. 10889-10896
-
-
Hoffman, H.M.1
Brydges, S.D.2
-
207
-
-
66149086936
-
NOD-like receptors: Role in innate immunity and inflammatory disease
-
Chen G, Shaw MH, Kim YG, Nunez G. NOD-like receptors: role in innate immunity and inflammatory disease. Annu Rev Pathol 2009;4:365-398.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 365-398
-
-
Chen, G.1
Shaw, M.H.2
Kim, Y.G.3
Nunez, G.4
-
208
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
DOI 10.1038/sj.emboj.7600175
-
Tanabe T, Chamaillard M, Ogura Y, et al. Regulatory regions and critical residues of NOD2 involved inmuramyl dipeptide recognition. EMBO J 2004;23:1587-1597. (Pubitemid 38579519)
-
(2004)
EMBO Journal
, vol.23
, Issue.7
, pp. 1587-1597
-
-
Tanabe, T.1
Chamaillard, M.2
Ogura, Y.3
Zhu, L.4
Qiu, S.5
Masumoto, J.6
Ghosh, P.7
Moran, A.8
Predergast, M.M.9
Tromp, G.10
Williams, C.J.11
Inohara, N.12
Nunez, G.13
-
209
-
-
0037452968
-
Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases
-
DOI 10.1073/pnas.0530276100
-
Chamaillard M, Philpott D, Girardin SE, et al. Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proc Natl Acad Sci USA 2003;100:3455-3460. (Pubitemid 36356605)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.6
, pp. 3455-3460
-
-
Chamaillard, M.1
Philpott, D.2
Girardin, S.E.3
Zouali, H.4
Lesage, S.5
Chareyre, F.6
Bui, T.H.7
Giovannini, M.8
Zaehringer, U.9
Penard-Lacronique, V.10
Sansonetti, P.J.11
Hugot, J.-P.12
Thomas, G.13
-
210
-
-
17944372335
-
CARD15 mutations in Blau syndrome
-
DOI 10.1038/ng720
-
Miceli-Richard C, Lesage S, Rybojad M, et al. CARD15 mutations in Blau syndrome. Nat Genet 2001;29:19-20. (Pubitemid 32801800)
-
(2001)
Nature Genetics
, vol.29
, Issue.1
, pp. 19-20
-
-
Miceli-Richard, C.1
Lesage, S.2
Rybojad, M.3
Prieur, A.-M.4
Manouvrier-Hanu, S.5
Hafner, R.6
Chamaillard, M.7
Zouali, H.8
Thomas, G.9
Hugot, J.-P.10
-
211
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
DOI 10.1038/35079114
-
Ogura Y, Bonen DK, Inohara N, et al. A frameshiftmutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001;411:603-606. (Pubitemid 32531409)
-
(2001)
Nature
, vol.411
, Issue.6837
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.-P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nuez, G.16
Cho, J.H.17
-
212
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
DOI 10.1038/35079107
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001;411:599-603. (Pubitemid 32531408)
-
(2001)
Nature
, vol.411
, Issue.6837
, pp. 599-603
-
-
Hugot, J.-P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.-P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Puig, P.15
Gower-Rousseau, C.16
Macry, J.17
Colombel, J.-F.18
Sahbatou, M.19
Thomas, G.20
more..
-
213
-
-
44349124113
-
The genetics and immunopathogenesis of inflammatory bowel disease
-
DOI 10.1038/nri2340, PII NRI2340
-
Cho JH. The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol 2008;8:458-466. (Pubitemid 351733422)
-
(2008)
Nature Reviews Immunology
, vol.8
, Issue.6
, pp. 458-466
-
-
Cho, J.H.1
-
214
-
-
11144279151
-
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: A metaanalysis
-
DOI 10.1111/j.1572-0241.2004.40304.x
-
Economou M, Trikalinos TA, Loizou KT, et al. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol 2004;99:2393-2404. (Pubitemid 40039371)
-
(2004)
American Journal of Gastroenterology
, vol.99
, Issue.12
, pp. 2393-2404
-
-
Economou, M.1
Trikalinos, T.A.2
Loizou, K.T.3
Tsianos, E.V.4
Ioannidis, J.P.A.5
-
215
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
DOI 10.1038/ng1954, PII NG1954
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007;39:207-211. (Pubitemid 46184351)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
216
-
-
84859253322
-
Agenome-wide scan of Ashkenazi JewishCrohn's disease suggests novel susceptibility loci
-
Kenny EE,Pe'er I,KarbanA, et al.Agenome-wide scan of Ashkenazi JewishCrohn's disease suggests novel susceptibility loci. PLoS Genet 2012;8:e1002559.
-
(2012)
PLoS Genet
, vol.8
-
-
Kenny, E.E.1
Pe'Er, I.2
Karban, A.3
-
217
-
-
77955398591
-
Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
-
McGovern DP, Jones MR, Taylor KD, et al. Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. HumMol Genet 2010;19:3468-3476.
-
(2010)
HumMol Genet
, vol.19
, pp. 3468-3476
-
-
McGovern, D.P.1
Jones, M.R.2
Taylor, K.D.3
-
218
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008;40:955-962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
219
-
-
35548958718
-
Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci
-
DOI 10.1073/pnas.0706645104
-
Raelson JV, Little RD, Ruether A, et al. Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci. Proc Natl Acad Sci USA 2007;104:14747-14752. (Pubitemid 350003214)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.37
, pp. 14747-14752
-
-
Raelson, J.V.1
Little, R.D.2
Ruether, A.3
Fournier, H.4
Paquin, B.5
Van Eerdewegh, P.6
Bradley, W.E.C.7
Croteau, P.8
Nguyen-Huu, Q.9
Segal, J.10
Debrus, S.11
Allard, R.12
Rosenstiel, P.13
Franke, A.14
Jacobs, G.15
Nikolaus, S.16
Vidal, J.-M.17
Szego, P.18
Laplante, N.19
Clark, H.F.20
Paulussen, R.21
Hooper, J.W.22
Keith, T.P.23
Belouchi, A.24
Schreiber, S.25
more..
-
220
-
-
84886948320
-
A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300
-
Julia A, Domenech E, Ricart E, et al. A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. Gut 2012.
-
(2012)
Gut
-
-
Julia, A.1
Domenech, E.2
Ricart, E.3
-
221
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
DOI 10.1038/ng2032, PII NG2032
-
Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007;39:596-604. (Pubitemid 46676115)
-
(2007)
Nature Genetics
, vol.39
, Issue.5
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
Green, T.7
Kuballa, P.8
Barmada, M.M.9
Datta, L.W.10
Shugart, Y.Y.11
Griffiths, A.M.12
Targan, S.R.13
Ippoliti, A.F.14
Bernard, E.-J.15
Mei, L.16
Nicolae, D.L.17
Regueiro, M.18
Schumm, L.P.19
Steinhart, A.H.20
Rotter, J.I.21
Duerr, R.H.22
Cho, J.H.23
Daly, M.J.24
Brant, S.R.25
more..
-
222
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Consortium WTCC
-
ConsortiumWTCC.Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007;447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
223
-
-
58149159542
-
Common variants in the NLRP3 region contribute to Crohn's disease susceptibility
-
Villani AC, Lemire M, Fortin G, et al. Common variants in the NLRP3 region contribute to Crohn's disease susceptibility. Nat Genet 2009;41:71-76.
-
(2009)
Nat Genet
, vol.41
, pp. 71-76
-
-
Villani, A.C.1
Lemire, M.2
Fortin, G.3
-
224
-
-
0345742508
-
Novel Vitiligo Susceptibility Loci on Chromosomes 7 (AIS2) and 8 (AIS3), Confirmation of SLEV1 on Chromosome 17, and Their Roles in an Autoimmune Diathesis
-
DOI 10.1086/381134
-
Spritz RA,Gowan K, BennettDC, Fain PR.Novel vitiligo susceptibility loci on chromosomes 7 (AIS2) and 8 (AIS3), confirmation of SLEV1 on chromosome 17, and their roles in an autoimmune diathesis. Am J Hum Genet 2004;74:188-191. (Pubitemid 38085251)
-
(2004)
American Journal of Human Genetics
, vol.74
, Issue.1
, pp. 188-191
-
-
Spritz, R.A.1
Gowan, K.2
Bennett, D.C.3
Fain, P.R.4
-
225
-
-
34447304633
-
Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population
-
DOI 10.1038/sj.jid.5700953, PII 5700953
-
Jin Y, Birlea SA, Fain PR, Spritz RA. Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population. J Invest Dermatol 2007;127:2558-2562. (Pubitemid 47585070)
-
(2007)
Journal of Investigative Dermatology
, vol.127
, Issue.11
, pp. 2558-2562
-
-
Jin, Y.1
Birlea, S.A.2
Fain, P.R.3
Spritz, R.A.4
-
226
-
-
33947497237
-
NALP1 in vitiligo-associated multiple autoimmune disease
-
DOI 10.1056/NEJMoa061592
-
Jin Y, Mailloux CM, Gowan K, et al. NALP1 in vitiligo-associated multiple autoimmune disease. N Engl JMed 2007;356:1216-1225. (Pubitemid 46465597)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.12
, pp. 1216-1225
-
-
Jin, Y.1
Mailloux, C.M.2
Gowan, K.3
Riccardi, S.L.4
Laberge, G.5
Bennett, D.C.6
Fain, P.R.7
Spritz, R.A.8
-
227
-
-
83755185626
-
NLRP1, a regulator of innate immunity associated with vitiligo
-
D'Osualdo A, Reed JC.NLRP1, a regulator of innate immunity associated with vitiligo. Pigment Cell Melanoma Res 2012;25:5-8.
-
(2012)
Pigment Cell Melanoma Res
, vol.25
, pp. 5-8
-
-
D'Osualdo, A.1
Reed, J.C.2
-
228
-
-
0037291793
-
Increased interleukin-6 and granulocyte-macrophage colony stimulating factor levels in the sera of patients with non-segmental vitiligo
-
Tu CX, Gu JS, Lin XR. Increased interleukin-6 and granulocyte-macrophage colony stimulating factor levels in the sera of patients with non-segmental vitiligo. J Dermatol Sci 2003;31:73-78.
-
(2003)
J Dermatol Sci
, vol.31
, pp. 73-78
-
-
Tu, C.X.1
Gu, J.S.2
Lin, X.R.3
-
229
-
-
33748748044
-
Sarcoidosis and NOD1 variation with impaired recognition of intracellular Propionibacterium acnes
-
DOI 10.1016/j.bbadis.2006.07.006, PII S092544390600144X
-
Tanabe T, Ishige I, Suzuki Y, et al. Sarcoidosis and NOD1 variation with impaired recognition of intracellular Propionibacterium acnes. Biochim Biophys Acta 2006;1762:794-801. (Pubitemid 44403051)
-
(2006)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1762
, Issue.9
, pp. 794-801
-
-
Tanabe, T.1
Ishige, I.2
Suzuki, Y.3
Aita, Y.4
Furukawa, A.5
Ishige, Y.6
Uchida, K.7
Suzuki, T.8
Takemura, T.9
Ikushima, S.10
Oritsu, M.11
Yokoyama, T.12
Fujimoto, Y.13
Fukase, K.14
Inohara, N.15
Nunez, G.16
Eishi, Y.17
-
230
-
-
20244364812
-
NOD1 variation, immunoglobulin E and asthma
-
DOI 10.1093/hmg/ddi087
-
Hysi P, Kabesch M, Moffatt MF, et al. NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet 2005;14:935-941. (Pubitemid 40533104)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.7
, pp. 935-941
-
-
Hysi, P.1
Kabesch, M.2
Moffatt, M.F.3
Schedel, M.4
Carr, D.5
Zhang, Y.6
Boardman, B.7
Von Mutius, E.8
Weiland, S.K.9
Leupold, W.10
Fritzsch, C.11
Klopp, N.12
Musk, A.W.13
James, A.14
Nunez, G.15
Inohara, N.16
Cookson, W.O.C.17
-
231
-
-
21344448610
-
Association of NOD1 polymorphisms with atopic eczema and related phenotypes
-
DOI 10.1016/j.jaci.2005.02.034, PII S0091674905005221
-
Weidinger S, Klopp N, Rummler L, et al. Association of NOD1 polymorphisms with atopic eczema and related phenotypes. J Allergy Clin Immunol 2005;116:177-184. (Pubitemid 40909765)
-
(2005)
Journal of Allergy and Clinical Immunology
, vol.116
, Issue.1
, pp. 177-184
-
-
Weidinger, S.1
Klopp, N.2
Rummler, L.3
Wagenpfeil, S.4
Novak, N.5
Baurecht, H.-J.6
Groer, W.7
Darsow, U.8
Heinrich, J.9
Gauger, A.10
Schafer, T.11
Jakob, T.12
Behrendt, H.13
Wichmann, H.-E.14
Ring, J.15
Illig, T.16
-
232
-
-
0030987044
-
Two novel mutations in the MHC class II transactivator CIITA in a second patient from MHC class II deficiency complementation group A
-
DOI 10.1007/s004390050403
-
Bontron S, Steimle V, Ucla C, et al. Two novel mutations in the MHC class II transactivator CIITA in a second patient from MHC class II deficiency complementation group A. Hum Genet 1997;99:541-546. (Pubitemid 27152107)
-
(1997)
Human Genetics
, vol.99
, Issue.4
, pp. 541-546
-
-
Bontron, S.1
Steimle, V.2
Ucla, C.3
Eibl, M.M.4
Mach, B.5
-
233
-
-
0033082169
-
A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome
-
Cressman DE, Chin KC, Taxman DJ, Ting JP. A defect in the nuclear translocation of CIITA causes a formof type II bare lymphocyte syndrome. Immunity 1999;10:163-171. (Pubitemid 29115622)
-
(1999)
Immunity
, vol.10
, Issue.2
, pp. 163-171
-
-
Cressman, D.E.1
Chin, K.-C.2
Taxman, D.J.3
Ting, J.P.-Y.4
-
234
-
-
0027490172
-
Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
-
DOI 10.1016/0092-8674(93)90685-J
-
Steimle V, Otten LA, Zufferey M, Mach B. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 1993;75:135-146. (Pubitemid 23306027)
-
(1993)
Cell
, vol.75
, Issue.1
, pp. 135-146
-
-
Steimle, V.1
Otten, L.A.2
Zufferey, M.3
Mach, B.4
-
235
-
-
0029075521
-
Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency
-
Zhou H, Glimcher LH. Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency. Immunity 1995;2:545-553.
-
(1995)
Immunity
, vol.2
, pp. 545-553
-
-
Zhou, H.1
Glimcher, L.H.2
-
236
-
-
33644932200
-
Regulation of MHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease
-
DOI 10.1111/j.1399-0039.2006.00557.x
-
Krawczyk M, ReithW. Regulation ofMHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease. Tissue Antigens 2006;67:183-197. (Pubitemid 43383366)
-
(2006)
Tissue Antigens
, vol.67
, Issue.3
, pp. 183-197
-
-
Krawczyk, M.1
Reith, W.2
-
237
-
-
0035064073
-
The bare lymphocyte syndrome and the regulation of MHC expression
-
DOI 10.1146/annurev.immunol.19.1.331
-
ReithW,Mach B.The bare lymphocyte syndrome and the regulation ofMHCexpression. Annu Rev Immunol 2001;19:331-373. (Pubitemid 32368039)
-
(2001)
Annual Review of Immunology
, vol.19
, pp. 331-373
-
-
Reith, W.1
Mach, B.2
-
238
-
-
20944445879
-
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction
-
DOI 10.1038/ng1544
-
Swanberg M, Lidman O, Padyukov L, et al. MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis,multiple sclerosis andmyocardial infarction. Nat Genet 2005;37:486-494. (Pubitemid 40617276)
-
(2005)
Nature Genetics
, vol.37
, Issue.5
, pp. 486-494
-
-
Swanberg, M.1
Lidman, O.2
Padyukov, L.3
Eriksson, P.4
Akesson, E.5
Jagodic, M.6
Lobell, A.7
Khademi, M.8
Borjesson, O.9
Lindgren, C.M.10
Lundman, P.11
Brookes, A.J.12
Kere, J.13
Luthman, H.14
Alfredsson, L.15
Hillert, J.16
Klareskog, L.17
Hamsten, A.18
Piehl, F.19
Olsson, T.20
more..
-
239
-
-
58949099391
-
Genome-wide association analysis of susceptibility and clinical phenotype inmultiple sclerosis
-
Baranzini SE,Wang J,Gibson RA, et al.Genome-wide association analysis of susceptibility and clinical phenotype inmultiple sclerosis. HumMol Genet 2009;18:767-778.
-
(2009)
HumMol Genet
, vol.18
, pp. 767-778
-
-
Baranzini, S.E.1
Wang, J.2
Gibson, R.A.3
-
240
-
-
40349113175
-
Mutations in NALP12 cause hereditary periodic fever syndromes
-
DOI 10.1073/pnas.0708616105
-
Jeru I, Duquesnoy P, Fernandes-Alnemri T, et al. Mutations in NALP12 cause hereditary periodic fever syndromes. Proc Natl Acad Sci USA 2008;105:1614-1619. (Pubitemid 351346563)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1614-1619
-
-
Jeru, I.1
Duquesnoy, P.2
Fernandes-Alnemri, T.3
Cochet, E.4
Yu, J.W.5
Lackmy-Port-Lis, M.6
Grimprel, E.7
Landman-Parker, J.8
Hentgen, V.9
Marlin, S.10
McElreavey, K.11
Sarkisian, T.12
Grateau, G.13
Alnemri, E.S.14
Amselem, S.15
-
241
-
-
0035080617
-
The risk of colorectal cancer in ulcerative colitis: A meta-analysis
-
DOI 10.1136/gut.48.4.526
-
Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a metaanalysis. Gut 2001;48:526-535. (Pubitemid 32234798)
-
(2001)
Gut
, vol.48
, Issue.4
, pp. 526-535
-
-
Eaden, J.A.1
Abrams, K.R.2
Mayberry, J.F.3
-
242
-
-
0028199221
-
Similarity of colorectal cancer in Crohn's disease and ulcerative colitis: Implications for carcinogenesis and prevention
-
Choi PM, Zelig MP. Similarity of colorectal cancer in Crohn's disease and ulcerative colitis: implications for carcinogenesis and prevention. Gut 1994;35:950-954.
-
(1994)
Gut
, vol.35
, pp. 950-954
-
-
Choi, P.M.1
Zelig, M.P.2
-
243
-
-
81855228056
-
Inflammasomes in intestinal inflammation and cancer
-
Chen GY, Nunez G. Inflammasomes in intestinal inflammation and cancer. Gastroenterology 2011;141:1986-1999.
-
(2011)
Gastroenterology
, vol.141
, pp. 1986-1999
-
-
Chen, G.Y.1
Nunez, G.2
-
245
-
-
80052962565
-
Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology
-
Kutikhin AG. Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology. HumImmunol 2011;72:955-968.
-
(2011)
HumImmunol
, vol.72
, pp. 955-968
-
-
Kutikhin, A.G.1
-
246
-
-
14044261247
-
Association between mutations in the CARD15/NOD2 gene and colorectal cancer in a Greek population
-
DOI 10.1002/ijc.20747
-
Papaconstantinou I, Theodoropoulos G, Gazouli M, et al. Association between mutations in the CARD15/NOD2 gene and colorectal cancer in a Greek population. Int J Cancer 2005;114: 433-435. (Pubitemid 40279965)
-
(2005)
International Journal of Cancer
, vol.114
, Issue.3
, pp. 433-435
-
-
Papaconstantinou, I.1
Theodoropoulos, G.2
Gazouli, M.3
Panoussopoulos, D.4
Mantzaris, G.J.5
Felekouras, E.6
Bramis, J.7
-
247
-
-
70749146442
-
Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer
-
Mockelmann N, von Schonfels W, Buch S, et al. Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer. BMC Gastroenterol 2009;9:79.
-
(2009)
BMC Gastroenterol
, vol.9
, pp. 79
-
-
Mockelmann, N.1
Von Schonfels, W.2
Buch, S.3
-
248
-
-
5644298412
-
NOD2 3020insC alone is not sufficient for colorectal cancer predisposition
-
DOI 10.1158/0008-5472.CAN-04-2364
-
Alhopuro P, Ahvenainen T, Mecklin JP, et al. NOD2 3020insC alone is not sufficient for colorectal cancer predisposition. Cancer Res 2004;64:7245-7247. (Pubitemid 39372060)
-
(2004)
Cancer Research
, vol.64
, Issue.20
, pp. 7245-7247
-
-
Alhopuro, P.1
Ahvenainen, T.2
Mecklin, J.-P.3
Juhola, M.4
Jarvinen, H.J.5
Karhu, A.6
Aaltonen, L.A.7
-
249
-
-
34248590274
-
No evidence for association of NOD2 R702W and G908R with colorectal cancer
-
DOI 10.1002/ijc.22651
-
Tuupanen S, Alhopuro P,Mecklin JP, et al. No evidence for association of NOD2 R702W and G908R with colorectal cancer. Int J Cancer 2007;121:76-79. (Pubitemid 46753853)
-
(2007)
International Journal of Cancer
, vol.121
, Issue.1
, pp. 76-79
-
-
Tuupanen, S.1
Alhopuro, P.2
Mecklin, J.-P.3
Jarvinen, H.4
Aaltonen, L.A.5
-
250
-
-
84862646126
-
Inflammasomepolymorphisms confer susceptibility to sporadic malignantmelanoma
-
VermaD, Bivik C, Farahani E, et al. Inflammasomepolymorphisms confer susceptibility to sporadic malignantmelanoma. Pigment CellMelanoma Res 2012;25:506-513.
-
(2012)
Pigment CellMelanoma Res
, vol.25
, pp. 506-513
-
-
Vermad Bivik, C.1
Farahani, E.2
-
251
-
-
33644615366
-
Mutations in NALP7 cause recurrent hydatidiformmoles and reproductive wastage in humans
-
Murdoch S, Djuric U,Mazhar B, et al.Mutations in NALP7 cause recurrent hydatidiformmoles and reproductive wastage in humans. Nat Genet 2006;38:300-302.
-
(2006)
Nat Genet
, vol.38
, pp. 300-302
-
-
Murdoch, S.1
Djuric, U.2
Mazhar, B.3
-
252
-
-
34447649380
-
Women heterozygous for NALP7/NLRP7mutations are at risk for reproductive wastage: Report of two novelmutations
-
Qian J, Deveault C, Bagga R, et al.Women heterozygous for NALP7/NLRP7mutations are at risk for reproductive wastage: report of two novelmutations. HumMutat 2007;28:741.
-
(2007)
HumMutat
, vol.28
, pp. 741
-
-
Qian, J.1
Deveault, C.2
Bagga, R.3
-
253
-
-
68049120454
-
Identification of 13 novel NLRP7mutations in 20 families with recurrent hydatidiform mole; Missense mutations cluster in the leucine-rich region
-
Wang CM, Dixon PH, Decordova S, et al. Identification of 13 novel NLRP7mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region. J Med Genet 2009;46:569-575.
-
(2009)
J Med Genet
, vol.46
, pp. 569-575
-
-
Wang, C.M.1
Dixon, P.H.2
Decordova, S.3
-
254
-
-
84862777492
-
Meta-analyses identify 13 loci associatedwith age atmenopause and highlight DNA repair and immune pathways
-
Stolk L, Perry JR,Chasman DI, et al.Meta-analyses identify 13 loci associatedwith age atmenopause and highlight DNA repair and immune pathways. Nat Genet 2012;44:260-268.
-
(2012)
Nat Genet
, vol.44
, pp. 260-268
-
-
Stolk, L.1
Perry, J.R.2
Chasman, D.I.3
-
255
-
-
79952069515
-
Meta-analysis of genome-wide association studies in > 80 000 subjects identifies multiple loci for C-reactive protein levels
-
Dehghan A, Dupuis J, Barbalic M, et al. Meta-analysis of genome-wide association studies in > 80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation 2011;123: 731-738.
-
(2011)
Circulation
, vol.123
, pp. 731-738
-
-
Dehghan, A.1
Dupuis, J.2
Barbalic, M.3
-
256
-
-
67849121952
-
Association of novel genetic Loci with circulating fibrinogen levels: A genome-wide association study in 6 population-based cohorts
-
Dehghan A, Yang Q, Peters A, et al. Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet 2009;2:125-133.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 125-133
-
-
Dehghan, A.1
Yang, Q.2
Peters, A.3
-
257
-
-
83055161438
-
New gene functions in megakaryopoiesis and platelet formation
-
Gieger C, Radhakrishnan A, Cvejic A, et al. New gene functions in megakaryopoiesis and platelet formation. Nature 2011;480:201-208.
-
(2011)
Nature
, vol.480
, pp. 201-208
-
-
Gieger, C.1
Radhakrishnan, A.2
Cvejic, A.3
-
258
-
-
84866358306
-
Genome-wide association study in a Swedish population yields support for greater CNV andMHCinvolvement in schizophrenia comparedwith bipolar disorder
-
Bergen SE, O'Dushlaine CT, Ripke S, et al. Genome-wide association study in a Swedish population yields support for greater CNV andMHCinvolvement in schizophrenia comparedwith bipolar disorder.Mol Psychiatry 2012;17:880-886.
-
(2012)
Mol Psychiatry
, vol.17
, pp. 880-886
-
-
Bergen, S.E.1
O'Dushlaine, C.T.2
Ripke, S.3
-
260
-
-
79961160191
-
Interleukin-1 inhibition by anakinra in refractory chronic tophaceous gout
-
Tran AP, Edelman J. Interleukin-1 inhibition by anakinra in refractory chronic tophaceous gout. Int J Rheum Dis 2011;14:e33-37.
-
(2011)
Int J Rheum Dis
, vol.14
-
-
Tran, A.P.1
Edelman, J.2
-
262
-
-
67650915065
-
Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome
-
Delaloye J, Roger T, Steiner-Tardivel QG, et al. Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathog 2009;5:e1000480.
-
(2009)
PLoS Pathog
, vol.5
-
-
Delaloye, J.1
Roger, T.2
Steiner-Tardivel, Q.G.3
-
263
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
-
Allen IC, Scull MA, Moore CB, et al.The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 2009;30:556-565.
-
(2009)
Immunity
, vol.30
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
-
264
-
-
77951295418
-
Influenza virus activates inflammasomes via its intracellularM2 ion channel
-
Ichinohe T, Pang IK, Iwasaki A. Influenza virus activates inflammasomes via its intracellularM2 ion channel. Nat Immunol 2010;11:404-410.
-
(2010)
Nat Immunol
, vol.11
, pp. 404-410
-
-
Ichinohe, T.1
Pang, I.K.2
Iwasaki, A.3
-
265
-
-
64049096334
-
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
-
Thomas PG, Dash P, Aldridge JR, Jr. et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity 2009;30: 566-575.
-
(2009)
Immunity
, vol.30
, pp. 566-575
-
-
Thomas, P.G.1
Dash, P.2
Aldridge Jr., J.R.3
-
266
-
-
70349459620
-
Activation of innate immune antiviral responses by Nod2
-
Sabbah A, Chang TH, Harnack R, et al. Activation of innate immune antiviral responses by Nod2. Nat Immunol 2009;10:1073-1080.
-
(2009)
Nat Immunol
, vol.10
, pp. 1073-1080
-
-
Sabbah, A.1
Chang, T.H.2
Harnack, R.3
-
267
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
Gross O, Poeck H, BscheiderM, et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 2009;459:433-436.
-
(2009)
Nature
, vol.459
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
-
268
-
-
65549154784
-
An essential role for the NLRP3 inflammasomein host defense against the human fungal pathogen Candida albicans
-
Hise AG, Tomalka J,Ganesan S, et al. An essential role for the NLRP3 inflammasomein host defense against the human fungal pathogen Candida albicans. Cell HostMicrobe 2009;5:487-497.
-
(2009)
Cell HostMicrobe
, vol.5
, pp. 487-497
-
-
Hise, A.G.1
Tomalka, J.2
Ganesan, S.3
-
269
-
-
77954958602
-
Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase
-
Said-Sadier N, Padilla E, Langsley G, Ojcius DM. Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase. PLoS One 2010;5:e10008.
-
(2010)
PLoS One
, vol.5
-
-
Said-Sadier, N.1
Padilla, E.2
Langsley, G.3
Ojcius, D.M.4
-
270
-
-
70349317039
-
Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome
-
Joly S,Ma N, Sadler JJ, et al. Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome. J Immunol 2009;183:3578-3581.
-
(2009)
J Immunol
, vol.183
, pp. 3578-3581
-
-
Joly, S.1
Ma, N.2
Sadler, J.J.3
-
271
-
-
68349157477
-
Malarial hemozoin is aNalp3 inflammasome activating danger signal
-
Dostert C, Guarda G, Romero JF, et al.Malarial hemozoin is aNalp3 inflammasome activating danger signal. PLoS One 2009;4:e6510.
-
(2009)
PLoS One
, vol.4
-
-
Dostert, C.1
Guarda, G.2
Romero, J.F.3
-
272
-
-
70049101754
-
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
-
Shio MT, Eisenbarth SC, Savaria M, et al. Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. PLoS Pathog 2009;5:e1000559.
-
(2009)
PLoS Pathog
, vol.5
-
-
Shio, M.T.1
Eisenbarth, S.C.2
Savaria, M.3
-
273
-
-
77749260601
-
Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome
-
Reimer T, Shaw MH, Franchi L, et al. Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome. Eur J Immunol 2010;40:764-769.
-
(2010)
Eur J Immunol
, vol.40
, pp. 764-769
-
-
Reimer, T.1
Shaw, M.H.2
Franchi, L.3
-
274
-
-
78650544477
-
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses
-
Ritter M, Gross O, Kays S, et al. Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses. Proc Natl Acad Sci USA 2010;107: 20459-20464.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20459-20464
-
-
Ritter, M.1
Gross, O.2
Kays, S.3
-
275
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
Poeck H, Bscheider M, Gross O, et al. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nature immunology 2010;11:63-69.
-
(2010)
Nature Immunology
, vol.11
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
-
276
-
-
80052058636
-
Ambivalent role of the innate immune response in rabies virus pathogenesis
-
Chopy D, Pothlichet J, Lafage M, et al. Ambivalent role of the innate immune response in rabies virus pathogenesis. J Virol 2011;85:6657-6668.
-
(2011)
J Virol
, vol.85
, pp. 6657-6668
-
-
Chopy, D.1
Pothlichet, J.2
Lafage, M.3
-
277
-
-
76549109497
-
LGP2 is a positive regulator of RIG-I-and MDA5-mediated antiviral responses
-
Satoh T, Kato H, Kumagai Y, et al. LGP2 is a positive regulator of RIG-I-and MDA5-mediated antiviral responses. Proc Natl Acad Sci USA 2010;107:1512-1517.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1512-1517
-
-
Satoh, T.1
Kato, H.2
Kumagai, Y.3
-
278
-
-
34248168157
-
Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses
-
Venkataraman T, Valdes M, Elsby R, et al. Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses. J Immunol 2007;178:6444-6455. (Pubitemid 46717428)
-
(2007)
Journal of Immunology
, vol.178
, Issue.10
, pp. 6444-6455
-
-
Venkataraman, T.1
Valdes, M.2
Elsby, R.3
Kakuta, S.4
Caceres, G.5
Saijo, S.6
Iwakura, Y.7
Barber, G.N.8
-
280
-
-
34147161091
-
Viral infections activate types I and III interferon genes through a common mechanism
-
DOI 10.1074/jbc.M608618200
-
Onoguchi K,YoneyamaM,Takemura A, et al.Viral infections activate types I andIII interferon genes through a commonmechanism. J Biol Chem 2007;282:7576-7581. (Pubitemid 47093699)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.10
, pp. 7576-7581
-
-
Onoguchi, K.1
Yoneyama, M.2
Takemura, A.3
Akira, S.4
Taniguchi, T.5
Namiki, H.6
Fujita, T.7
-
281
-
-
75149189005
-
Type i interferons: Crucial participants in disease amplification in autoimmunity
-
Hall JC, Rosen A. Type I interferons: crucial participants in disease amplification in autoimmunity. Nat Rev Rheumatol 2010;6:40-49.
-
(2010)
Nat Rev Rheumatol
, vol.6
, pp. 40-49
-
-
Hall, J.C.1
Rosen, A.2
-
282
-
-
84862748323
-
Janus-like effects of type i interferon in autoimmune diseases
-
Axtell RC, Raman C. Janus-like effects of type I interferon in autoimmune diseases. Immunol Rev 2012;248:23-35.
-
(2012)
Immunol Rev
, vol.248
, pp. 23-35
-
-
Axtell, R.C.1
Raman, C.2
-
283
-
-
84857415635
-
Constitutive type i interferon modulates homeostatic balance through tonic signaling
-
Gough DJ, Messina NL, Clarke CJ, et al. Constitutive type I interferon modulates homeostatic balance through tonic signaling. Immunity 2012;36:166-174.
-
(2012)
Immunity
, vol.36
, pp. 166-174
-
-
Gough, D.J.1
Messina, N.L.2
Clarke, C.J.3
-
284
-
-
70449568252
-
Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response
-
Pothlichet J, Burtey A, Kubarenko AV, et al. Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response. PLoS One 2009;4:e7582.
-
(2009)
PLoS One
, vol.4
-
-
Pothlichet, J.1
Burtey, A.2
Kubarenko, A.V.3
-
285
-
-
67649415364
-
Identification of loss of function mutations in human genes encoding RIG-I and MDA5: Implications for resistance to type i diabetes
-
Shigemoto T, Kageyama M, Hirai R, et al. Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes. J Biol Chem 2009;284:13348-13354.
-
(2009)
J Biol Chem
, vol.284
, pp. 13348-13354
-
-
Shigemoto, T.1
Kageyama, M.2
Hirai, R.3
-
286
-
-
77956195791
-
A common polymorphism in the caspase recruitment domain of RIG-Imodifies the innateimmune response of human dendritic cells
-
Hu J,Nistal-Villan E, Voho A, et al. A common polymorphism in the caspase recruitment domain of RIG-Imodifies the innateimmune response of human dendritic cells. JImmunol 2010;185:424-432.
-
(2010)
JImmunol
, vol.185
, pp. 424-432
-
-
Hu, J.1
Nistal-Villan, E.2
Voho, A.3
-
287
-
-
75649144807
-
Polymorphisms in the vitamin A receptor and innate immunity genes influence the antibody response to rubella vaccination
-
Ovsyannikova IG, Haralambieva IH, Dhiman N, et al. Polymorphisms in the vitamin A receptor and innate immunity genes influence the antibody response to rubella vaccination. J Infect Dis 2010;201:207-213.
-
(2010)
J Infect Dis
, vol.201
, pp. 207-213
-
-
Ovsyannikova, I.G.1
Haralambieva, I.H.2
Dhiman, N.3
-
288
-
-
76449083752
-
Interferon inducedwith helicase C domain 1 (IFIH1) and virus-induced autoimmunity: A review
-
Chistiakov DA. Interferon inducedwith helicase C domain 1 (IFIH1) and virus-induced autoimmunity: a review. Viral Immunol 2010;23:3-15.
-
(2010)
Viral Immunol
, vol.23
, pp. 3-15
-
-
Chistiakov, D.A.1
-
289
-
-
33745240931
-
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region
-
DOI 10.1038/ng1800, PII N1800
-
Smyth DJ, Cooper JD, Bailey R, et al. A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet 2006;38:617-619. (Pubitemid 43927300)
-
(2006)
Nature Genetics
, vol.38
, Issue.6
, pp. 617-619
-
-
Smyth, D.J.1
Cooper, J.D.2
Bailey, R.3
Field, S.4
Burren, O.5
Smink, L.J.6
Guja, C.7
Ionescu-Tirgoviste, C.8
Widmer, B.9
Dunger, D.B.10
Savage, D.A.11
Walker, N.M.12
Clayton, D.G.13
Todd, J.A.14
-
290
-
-
58149090841
-
A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3
-
Concannon P, Onengut-Gumuscu S, Todd JA, et al. A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3. Diabetes 2008;57:2858-2861.
-
(2008)
Diabetes
, vol.57
, pp. 2858-2861
-
-
Concannon, P.1
Onengut-Gumuscu, S.2
Todd, J.A.3
-
291
-
-
58049198421
-
IFIH1 polymorphisms are significantly associatedwith type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells
-
Liu S,WangH, Jin Y, et al. IFIH1 polymorphisms are significantly associatedwith type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells. HumMol Genet 2009;18:358-365.
-
(2009)
HumMol Genet
, vol.18
, pp. 358-365
-
-
Liu, S.1
Wang, H.2
Jin, Y.3
-
292
-
-
67349199566
-
Genome-wide association study andmeta-analysis find that over 40 loci affect risk of type 1 diabetes
-
Barrett JC, ClaytonDG, Concannon P, et al.Genome-wide association study andmeta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet 2009;41:703-707.
-
(2009)
Nat Genet
, vol.41
, pp. 703-707
-
-
Barrett, J.C.1
Clayton, D.G.2
Concannon, P.3
-
293
-
-
65249131713
-
Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes
-
Nejentsev S, Walker N, Riches D, et al. Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. Science 2009;324:387-389.
-
(2009)
Science
, vol.324
, pp. 387-389
-
-
Nejentsev, S.1
Walker, N.2
Riches, D.3
-
294
-
-
78049347495
-
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
-
Strange A, Capon F, Spencer CC, et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 2010;42:985-990.
-
(2010)
Nat Genet
, vol.42
, pp. 985-990
-
-
Strange, A.1
Capon, F.2
Spencer, C.C.3
-
295
-
-
80051619284
-
Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-alpha and serologic autoimmunity in lupus patients
-
Robinson T, Kariuki SN, Franek BS, et al. Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-alpha and serologic autoimmunity in lupus patients. J Immunol 2011;187:1298-1303.
-
(2011)
J Immunol
, vol.187
, pp. 1298-1303
-
-
Robinson, T.1
Kariuki, S.N.2
Franek, B.S.3
-
296
-
-
78049344947
-
Interferon-induced helicase (IFIH1) polymorphismwith systemic lupus erythematosus and dermatomyositis/polymyositis
-
Gono T, Kawaguchi Y, Sugiura T, et al. Interferon-induced helicase (IFIH1) polymorphismwith systemic lupus erythematosus and dermatomyositis/ polymyositis.Mod Rheumatol 2010;20:466-470.
-
(2010)
Mod Rheumatol
, vol.20
, pp. 466-470
-
-
Gono, T.1
Kawaguchi, Y.2
Sugiura, T.3
-
297
-
-
70350650472
-
Alarge-scale replication study identifies TNIP1 PRDM1 JAZF1 UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
-
Gateva V, Sandling JK,HomG, et al.Alarge-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet 2009;41:1228-1233.
-
(2009)
Nat Genet
, vol.41
, pp. 1228-1233
-
-
Gateva, V.1
Sandling, J.K.2
Hom, G.3
-
298
-
-
77956646451
-
Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency
-
Ferreira RC, Pan-HammarstromQ, Graham RR, et al. Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency. Nat Genet 2010;42:777-780.
-
(2010)
Nat Genet
, vol.42
, pp. 777-780
-
-
Ferreira, R.C.1
Pan-Hammarstrom, Q.2
Graham, R.R.3
-
299
-
-
77958526517
-
Reduced expression of IFIH1 is protective for type 1 diabetes
-
Downes K, Pekalski M, AngusKL, et al. Reduced expression of IFIH1 is protective for type 1 diabetes. PLoS One 2010;5.
-
(2010)
PLoS One
, pp. 5
-
-
Downes, K.1
Pekalski, M.2
Angus, K.L.3
-
300
-
-
77956640135
-
Enteroviruses and type 1 diabetes: Towards a better understanding of the relationship
-
JaidaneH, Sauter P, Sane F, et al. Enteroviruses and type 1 diabetes: towards a better understanding of the relationship. RevMed Virol 2010;20:265-280.
-
(2010)
RevMed Virol
, vol.20
, pp. 265-280
-
-
Jaidane, H.1
Sauter, P.2
Sane, F.3
-
301
-
-
77649326700
-
MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA
-
Colli ML, Moore F, Gurzov EN, et al. MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA. Hum Mol Genet 2010;19:135-146.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 135-146
-
-
Colli, M.L.1
Moore, F.2
Gurzov, E.N.3
-
302
-
-
79953318392
-
RNA sensor-induced type i IFN prevents diabetes caused by a beta cell-tropic virus in mice
-
McCartney SA, VermiW, Lonardi S, et al. RNA sensor-induced type I IFN prevents diabetes caused by a beta cell-tropic virus in mice. J Clin Invest 2011;121:1497-1507.
-
(2011)
J Clin Invest
, vol.121
, pp. 1497-1507
-
-
McCartney, S.A.1
Vermi, W.2
Lonardi, S.3
-
303
-
-
79952094197
-
A loss-of-function variant of the antiviralmoleculeMAVS is associated with a subset of systemic lupus patients
-
Pothlichet J, Niewold TB, Vitour D, et al. A loss-of-function variant of the antiviralmoleculeMAVS is associated with a subset of systemic lupus patients. EMBOMolMed 2011;3:142-152.
-
(2011)
EMBOMolMed
, vol.3
, pp. 142-152
-
-
Pothlichet, J.1
Niewold, T.B.2
Vitour, D.3
-
304
-
-
80052512306
-
Possible association of VISA gene polymorphisms with susceptibility to systemic lupus erythematosus in Chinese population
-
Liu X, Jiao Y, Wen X, et al. Possible association of VISA gene polymorphisms with susceptibility to systemic lupus erythematosus in Chinese population.Mol Biol Rep 2011;38:4583-4588.
-
(2011)
Mol Biol Rep
, vol.38
, pp. 4583-4588
-
-
Liu, X.1
Jiao, Y.2
Wen, X.3
-
305
-
-
35348839535
-
-/- mice develop colitis associated with downregulation of Gαi2
-
DOI 10.1038/cr.2007.81, PII CR200781
-
Wang Y, Zhang HX, Sun YP, et al. Rig-I-/-mice develop colitis associated with downregulation of G alpha i2. Cell Res 2007;17:858-868. (Pubitemid 47585114)
-
(2007)
Cell Research
, vol.17
, Issue.10
, pp. 858-868
-
-
Wang, Y.1
Zhang, H.-X.2
Sun, Y.-P.3
Liu, Z.-X.4
Liu, X.-S.5
Wang, L.6
Lu, S.-Y.7
Kong, H.8
Liu, Q.-L.9
Li, X.-H.10
Lu, Z.-Y.11
Chen, S.-J.12
Chen, Z.13
Bao, S.-S.14
Dai, W.15
Wang, Z.-G.16
-
306
-
-
79956302548
-
Selective downregulation of retinoic acid-inducible gene i within the intestinal epithelial compartment in Crohn's disease
-
Funke B, Lasitschka F, Roth W, et al. Selective downregulation of retinoic acid-inducible gene I within the intestinal epithelial compartment in Crohn's disease. Inflamm Bowel Dis 2011;17:1943-1954.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1943-1954
-
-
Funke, B.1
Lasitschka, F.2
Roth, W.3
-
307
-
-
84865793305
-
Innate immune sensing of cancer: Clues from an identified role for type i IFNs
-
Gajewski TF, FuertesMB, Woo SR. Innate immune sensing of cancer: clues from an identified role for type I IFNs. Cancer Immunol Immunother 2012;61:1343-1347.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 1343-1347
-
-
Gajewski, T.F.1
Fuertes, M.B.2
Woo, S.R.3
-
309
-
-
84865394537
-
Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility
-
ChoubeyD. Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility. Immunol Lett 2012;147:10-17.
-
(2012)
Immunol Lett
, vol.147
, pp. 10-17
-
-
Choubey, D.1
-
310
-
-
81355146737
-
Cytosolic DNA sensors regulating type i interferon induction
-
Keating SE, Baran M, Bowie AG. Cytosolic DNA sensors regulating type I interferon induction. Trends Immunol 2011;32:574-581.
-
(2011)
Trends Immunol
, vol.32
, pp. 574-581
-
-
Keating, S.E.1
Baran, M.2
Bowie, A.G.3
-
312
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, et al. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 2009;458:509-513.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
-
313
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Burckstummer T, Baumann C, Bluml S, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nature immunology 2009;10: 266-272.
-
(2009)
Nature Immunology
, vol.10
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Bluml, S.3
-
314
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, et al. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 2009;323:1057-1060.
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
-
315
-
-
79952262073
-
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci
-
Zhernakova A, Stahl EA, Trynka G, et al. Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. PLoS Genet 2011;7:e1002004.
-
(2011)
PLoS Genet
, vol.7
-
-
Zhernakova, A.1
Stahl, E.A.2
Trynka, G.3
-
316
-
-
84857753583
-
Immunology in the clinic review series; Focus on type 1 diabetes and viruses: The enterovirus link to type 1 diabetes: Critical review of human studies
-
Stene LC, Rewers M. Immunology in the clinic review series; focus on type 1 diabetes and viruses: the enterovirus link to type 1 diabetes: critical review of human studies. Clin Exp Immunol 2012;168:12-23.
-
(2012)
Clin Exp Immunol
, vol.168
, pp. 12-23
-
-
Stene, L.C.1
Rewers, M.2
-
317
-
-
84857751555
-
Immunology in the clinic review series: Focus on type 1 diabetes and viruses: The role of viruses in type 1 diabetes: A difficult dilemma
-
Coppieters KT, Wiberg A, Tracy SM, vonHerrath MG. Immunology in the clinic review series: focus on type 1 diabetes and viruses: the role of viruses in type 1 diabetes: a difficult dilemma. Clin Exp Immunol 2012;168:5-11.
-
(2012)
Clin Exp Immunol
, vol.168
, pp. 5-11
-
-
Coppieters, K.T.1
Wiberg, A.2
Tracy, S.M.3
Vonherrath, M.G.4
-
318
-
-
84857737745
-
Immunology in the clinic review series; Focus on type 1 diabetes and viruses: The innate immune response to enteroviruses and its possible role in regulating type 1 diabetes
-
Lind K, Huhn MH, Flodstrom-Tullberg M. Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes. Clin Exp Immunol 2012;168:30-38.
-
(2012)
Clin Exp Immunol
, vol.168
, pp. 30-38
-
-
Lind, K.1
Huhn, M.H.2
Flodstrom-Tullberg, M.3
-
319
-
-
84857700539
-
Immunology in the clinic review series; Focus on type 1 diabetes and viruses: How viral infections modulate beta cell function
-
Grieco FA, Sebastiani G, Spagnuolo I, et al. Immunology in the clinic review series; focus on type 1 diabetes and viruses: how viral infections modulate beta cell function. Clin Exp Immunol 2012;168:24-29.
-
(2012)
Clin Exp Immunol
, vol.168
, pp. 24-29
-
-
Grieco, F.A.1
Sebastiani, G.2
Spagnuolo, I.3
-
320
-
-
84857728420
-
Immunology in the clinic review series; Focus on type 1 diabetes and viruses: Role of antibodies enhancing the infection with Coxsackievirus-B in the pathogenesis of type 1 diabetes
-
Hober D, Sane F, Jaidane H, et al. Immunology in the clinic review series; focus on type 1 diabetes and viruses: role of antibodies enhancing the infection with Coxsackievirus-B in the pathogenesis of type 1 diabetes. Clin Exp Immunol 2012;168:47-51.
-
(2012)
Clin Exp Immunol
, vol.168
, pp. 47-51
-
-
Hober, D.1
Sane, F.2
Jaidane, H.3
-
321
-
-
84857715156
-
Immunology in the clinic review series; Focus on type 1 diabetes and viruses: Enterovirus, thymus and type 1 diabetes pathogenesis
-
Jaidane H, Sane F, Hiar R, et al. Immunology in the clinic review series; focus on type 1 diabetes and viruses: enterovirus, thymus and type 1 diabetes pathogenesis. Clin Exp Immunol 2012;168: 39-46.
-
(2012)
Clin Exp Immunol
, vol.168
, pp. 39-46
-
-
Jaidane, H.1
Sane, F.2
Hiar, R.3
-
322
-
-
84864924195
-
Epstein-Barr virus and systemic lupus erythematosus
-
Draborg AH, Duus K, Houen G. Epstein-Barr virus and systemic lupus erythematosus. Clin Dev Immunol 2012;2012:370516.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 370516
-
-
Draborg, A.H.1
Duus, K.2
Houen, G.3
-
323
-
-
77952899400
-
Clinical and molecular evidence for association of SLE with parvovirus B19
-
Pavlovic M, Kats A, Cavallo M, Shoenfeld Y. Clinical and molecular evidence for association of SLE with parvovirus B19. Lupus 2010;19:783-792.
-
(2010)
Lupus
, vol.19
, pp. 783-792
-
-
Pavlovic, M.1
Kats, A.2
Cavallo, M.3
Shoenfeld, Y.4
-
324
-
-
0142053206
-
The immunological and genetic basis of inflammatory bowel disease
-
DOI 10.1038/nri1132
-
Bouma G, Strober W.Theimmunological and genetic basis of inflammatory bowel disease.Nat Rev Immunol 2003;3:521-533. (Pubitemid 37328672)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.7
, pp. 521-533
-
-
Bouma, G.1
Strober, W.2
-
325
-
-
79959647082
-
RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications
-
Ireton RC, Gale M, Jr. RIG-I Like Receptors in Antiviral Immunity and Therapeutic Applications. Viruses 2011;3:906-919.
-
(2011)
Viruses
, vol.3
, pp. 906-919
-
-
Ireton, R.C.1
Gale Jr., M.2
-
326
-
-
78650370346
-
Anticancer function of polyinosinic-polycytidylic acid
-
Cheng YS, Xu F. Anticancer function of polyinosinic-polycytidylic acid. Cancer Biol Ther 2011;10:1219-1223.
-
(2011)
Cancer Biol Ther
, vol.10
, pp. 1219-1223
-
-
Cheng, Y.S.1
Xu, F.2
-
327
-
-
79952762940
-
Thepharmacokinetics of Toll-like receptor agonists and the impact on the immune system
-
Engel AL,Holt GE, Lu H.Thepharmacokinetics of Toll-like receptor agonists and the impact on the immune system. Expert Rev Clin Pharmacol 2011;4:275-289.
-
(2011)
Expert Rev Clin Pharmacol
, vol.4
, pp. 275-289
-
-
Engel, A.L.1
Holt, G.E.2
Lu, H.3
-
328
-
-
72049122659
-
Drugs targeting Toll-like receptors
-
Krishnan J, Lee G, Choi S. Drugs targeting Toll-like receptors. Arch PharmRes 2009;32:1485-1502.
-
(2009)
Arch PharmRes
, vol.32
, pp. 1485-1502
-
-
Krishnan, J.1
Lee, G.2
Choi, S.3
-
330
-
-
77956615100
-
Toll-like receptors, tumor necrosis factor-alpha, and interleukin-10 gene polymorphisms in risk of pulmonary tuberculosis and disease severity
-
Ma MJ, Xie LP, Wu SC, et al. Toll-like receptors, tumor necrosis factor-alpha, and interleukin-10 gene polymorphisms in risk of pulmonary tuberculosis and disease severity. Hum Immunol 2010;71:1005-1010.
-
(2010)
Hum Immunol
, vol.71
, pp. 1005-1010
-
-
Ma, M.J.1
Xie, L.P.2
Wu, S.C.3
-
331
-
-
84856248937
-
Variants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory disease
-
Taylor BD, Darville T, Ferrell RE, et al. Variants in toll-like receptor 1 and 4 genes are associated with Chlamydia trachomatis among women with pelvic inflammatory disease. J Infect Dis 2012;205:603-609.
-
(2012)
J Infect Dis
, vol.205
, pp. 603-609
-
-
Taylor, B.D.1
Darville, T.2
Ferrell, R.E.3
-
332
-
-
79952132519
-
Toll-like receptor 1 gene polymorphisms in childhood IgA nephropathy: A case-control study in the Korean population
-
Lee JS, Park HK, Suh JS, et al. Toll-like receptor 1 gene polymorphisms in childhood IgA nephropathy: a case-control study in the Korean population. Int J Immunogenet 2011;38:133-138.
-
(2011)
Int J Immunogenet
, vol.38
, pp. 133-138
-
-
Lee, J.S.1
Park, H.K.2
Suh, J.S.3
-
333
-
-
77955403865
-
FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women
-
Barnholtz-Sloan JS, Shetty PB, Guan X, et al. FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women. Carcinogenesis 2010;31:1417-1423.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1417-1423
-
-
Barnholtz-Sloan, J.S.1
Shetty, P.B.2
Guan, X.3
-
334
-
-
60149086960
-
A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma
-
Purdue MP, Lan Q,Wang SS, et al. A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma. Carcinogenesis 2009;30:275-281.
-
(2009)
Carcinogenesis
, vol.30
, pp. 275-281
-
-
Purdue, M.P.1
Lan, Q.2
Wang, S.S.3
-
335
-
-
57349182159
-
Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk
-
StevensVL,HsingAW,Talbot JT, et al.Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk. Int J Cancer 2008;123:2644-2650.
-
(2008)
Int J Cancer
, vol.123
, pp. 2644-2650
-
-
Stevens, V.L.1
Hsing, A.W.2
Talbot, J.T.3
-
336
-
-
34247548755
-
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
-
DOI 10.1038/ng2022, PII NG2022
-
Yeager M, Orr N, Hayes RB, et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet 2007;39:645-649. (Pubitemid 46676108)
-
(2007)
Nature Genetics
, vol.39
, Issue.5
, pp. 645-649
-
-
Yeager, M.1
Orr, N.2
Hayes, R.B.3
Jacobs, K.B.4
Kraft, P.5
Wacholder, S.6
Minichiello, M.J.7
Fearnhead, P.8
Yu, K.9
Chatterjee, N.10
Wang, Z.11
Welch, R.12
Staats, B.J.13
Calle, E.E.14
Feigelson, H.S.15
Thun, M.J.16
Rodriguez, C.17
Albanes, D.18
Virtamo, J.19
Weinstein, S.20
Schumacher, F.R.21
Giovannucci, E.22
Willett, W.C.23
Cancel-Tassin, G.24
Cussenot, O.25
Valeri, A.26
Andriole, G.L.27
Gelmann, E.P.28
Tucker, M.29
Gerhard, D.S.30
Fraumeni Jr., J.F.31
Hoover, R.32
Hunter, D.J.33
Chanock, S.J.34
Thomas, G.35
more..
-
337
-
-
77949751401
-
Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies
-
Lindstrom S, Hunter DJ, Gronberg H, et al. Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies. Cancer Epidemiol Biomarkers Prev 2010;19:873-876.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 873-876
-
-
Lindstrom, S.1
Hunter, D.J.2
Gronberg, H.3
-
338
-
-
35448943896
-
Association between toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer
-
DOI 10.1158/1055-9965.EPI-07-0325
-
Chen YC, Giovannucci E, Kraft P, et al. Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer. Cancer Epidemiol Biomarkers Prev 2007;16:1982-1989. (Pubitemid 47621171)
-
(2007)
Cancer Epidemiology Biomarkers and Prevention
, vol.16
, Issue.10
, pp. 1982-1989
-
-
Chen, Y.-C.1
Giovannucci, E.2
Kraft, P.3
Lazarus, R.4
Hunter, D.J.5
-
339
-
-
15944377845
-
Sequence variants in toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk
-
DOI 10.1093/jnci/dji070
-
Sun J,Wiklund F, Zheng SL, et al. Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk. J Natl Cancer Inst 2005;97:525-532. (Pubitemid 40590434)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.7
, pp. 525-532
-
-
Sun, J.1
Wiklund, F.2
Zheng, S.L.3
Chang, B.4
Balter, K.5
Li, L.6
Johansson, J.-E.7
Li, G.8
Adami, H.-O.9
Liu, W.10
Tolin, A.11
Turner, A.R.12
Meyers, D.A.13
Isaacs, W.B.14
Xu, J.15
Gronberg, H.16
-
340
-
-
84865352586
-
Toll-like receptor gene polymorphisms confer susceptibility to graft-versus-host disease in allogenic hematopoietic stem cell transplantation
-
Sivula J, Cordova ZM, Tuimala J, et al. Toll-like receptor gene polymorphisms confer susceptibility to graft-versus-host disease in allogenic
-
(2012)
Scand J Immunol
, vol.76
, pp. 336-341
-
-
Sivula, J.1
Cordova, Z.M.2
Tuimala, J.3
-
341
-
-
84856107641
-
The toll-like receptor 2 (TLR2)-196 to-174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C
-
Nischalke HD, Coenen M, Berger C, et al.The toll-like receptor 2 (TLR2)-196 to-174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C. Int J Cancer 2012;130:1470-1475.
-
(2012)
Int J Cancer
, vol.130
, pp. 1470-1475
-
-
Nischalke, H.D.1
Coenen, M.2
Berger, C.3
-
342
-
-
79959594519
-
Toll-like receptor 2 gene polymorphisms in a Korean population: Association with chronic rhinosinusitis
-
Park CS, Cho JH, Park YJ. Toll-like receptor 2 gene polymorphisms in a Korean population: association with chronic rhinosinusitis. Otolaryngol Head Neck Surg 2011;144:96-100.
-
(2011)
Otolaryngol Head Neck Surg
, vol.144
, pp. 96-100
-
-
Park, C.S.1
Cho, J.H.2
Park, Y.J.3
-
343
-
-
0034891984
-
Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients
-
Kang TJ, Chae GT. Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients. FEMS ImmunolMedMicrobiol 2001;31:53-58.
-
(2001)
FEMS ImmunolMedMicrobiol
, vol.31
, pp. 53-58
-
-
Kang, T.J.1
Chae, G.T.2
-
344
-
-
0033794461
-
A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection
-
Lorenz E, Mira JP, Cornish KL, et al. A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection. Infect Immun 2000;68:6398-6401.
-
(2000)
Infect Immun
, vol.68
, pp. 6398-6401
-
-
Lorenz, E.1
Mira, J.P.2
Cornish, K.L.3
-
345
-
-
9144264994
-
Lack of association between toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus
-
DOI 10.1128/CDLI.11.6.1194-1197.2004
-
Moore CE, Segal S, Berendt AR, et al. Lack of association between Toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus. Clin Diagn Lab Immunol 2004;11:1194-1197. (Pubitemid 39540867)
-
(2004)
Clinical and Diagnostic Laboratory Immunology
, vol.11
, Issue.6
, pp. 1194-1197
-
-
Moore, C.E.1
Segal, S.2
Berendt, A.R.3
Hill, A.V.S.4
Day, N.P.J.5
-
346
-
-
67849092262
-
Impact of Toll-like receptors [TLR] 2 (-196 to-174 del) and TLR 4 (Asp299Gly,Thr399Ile) in cervical cancer susceptibility inNorth Indian women
-
Pandey S,Mittal RD, SrivastavaM, et al. Impact of Toll-like receptors [TLR] 2 (-196 to-174 del) and TLR 4 (Asp299Gly,Thr399Ile) in cervical cancer susceptibility inNorth Indian women.GynecolOncol 2009;114:501-505.
-
(2009)
GynecolOncol
, vol.114
, pp. 501-505
-
-
Pandey, S.1
Mittal, R.D.2
Srivastava, M.3
-
347
-
-
33846967820
-
Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk
-
DOI 10.1038/sj.gene.6364337, PII 6364337
-
Nieters A, Beckmann L, Deeg E, Becker N. Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk. Genes Immun 2006;7:615-624. (Pubitemid 46242365)
-
(2006)
Genes and Immunity
, vol.7
, Issue.8
, pp. 615-624
-
-
Nieters, A.1
Beckmann, L.2
Deeg, E.3
Becker, N.4
-
348
-
-
33745815169
-
Microsatellite GT polymorphism in the toll-like receptor 2 is associated with colorectal cancer
-
DOI 10.1111/j.1399-0004.2006.00651.x
-
Boraska Jelavic T, BarisicM, Drmic Hofman I, et al.Microsatelite GT polymorphism in the toll-like receptor 2 is associated with colorectal cancer. Clin Genet 2006;70:156-160. (Pubitemid 44028102)
-
(2006)
Clinical Genetics
, vol.70
, Issue.2
, pp. 156-160
-
-
Boraska Jelavic, T.1
Barisic, M.2
Drmic Hofman, I.3
Boraska, V.4
Vrdoljak, E.5
Peruzovic, M.6
Hozo, I.7
Puljiz, Z.8
Terzic, J.9
-
349
-
-
77957134823
-
Significant association between toll-like receptor gene polymorphisms and gallbladder cancer
-
Srivastava K, Srivastava A,Kumar A,Mittal B. Significant association between toll-like receptor gene polymorphisms and gallbladder cancer. Liver Int 2010;30:1067-1072.
-
(2010)
Liver Int
, vol.30
, pp. 1067-1072
-
-
Srivastava, K.1
Srivastava, A.2
Kumar, A.3
Mittal, B.4
-
350
-
-
34748867825
-
Toll-like receptor 2 - 196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancer
-
DOI 10.1111/j.1349-7006.2007.00590.x
-
Tahara T, Arisawa T,Wang F, et al. Toll-like receptor 2-196 to 174del polymorphism influences the susceptibility of Japanese people to gastric cancer. Cancer Sci 2007;98:1790-1794. (Pubitemid 47487917)
-
(2007)
Cancer Science
, vol.98
, Issue.11
, pp. 1790-1794
-
-
Tahara, T.1
Arisawa, T.2
Wang, F.3
Shibata, T.4
Nakamura, M.5
Sakata, M.6
Hirata, I.7
Nakano, H.8
-
351
-
-
84859413258
-
Association studies of gene polymorphisms in toll-like receptors 2 and 4 in Croatian patients with acute myocardial infarction
-
Dzumhur A, Zibar L, Wagner J, et al. Association studies of gene polymorphisms in toll-like receptors 2 and 4 in Croatian patients with acute myocardial infarction. Scand J Immunol 2012;75:517-523.
-
(2012)
Scand J Immunol
, vol.75
, pp. 517-523
-
-
Dzumhur, A.1
Zibar, L.2
Wagner, J.3
-
352
-
-
80855123487
-
Low frequency of Toll-like receptors 2 and 4 gene polymorphisms inMexican patients and their associationwith type 2 diabetes
-
Maldonado-Bernal C, Trejo-dela OA, Sanchez-Contreras ME, et al. Low frequency of Toll-like receptors 2 and 4 gene polymorphisms inMexican patients and their associationwith type 2 diabetes. Int J Immunogenet 2011;38:519-523.
-
(2011)
Int J Immunogenet
, vol.38
, pp. 519-523
-
-
Maldonado-Bernal, C.1
Trejo-Dela, O.A.2
Sanchez-Contreras, M.E.3
-
353
-
-
84864058577
-
Association of TLR3-hyporesponsiveness and functional TLR3 L412F polymorphism with recurrent herpes labialis
-
Yang CA, Raftery MJ, Hamann L, et al. Association of TLR3- hyporesponsiveness and functional TLR3 L412F polymorphism with recurrent herpes labialis. Hum Immunol 2012;73:844-851.
-
(2012)
Hum Immunol
, vol.73
, pp. 844-851
-
-
Yang, C.A.1
Raftery, M.J.2
Hamann, L.3
-
354
-
-
4444223628
-
Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women
-
DOI 10.1016/j.ejogrb.2004.02.010, PII S0301211504000740
-
Genc MR, Vardhana S,DelaneyML, et al. Relationship between a toll-like receptor-4 gene polymorphism, bacterial vaginosis-related flora and vaginal cytokine responses in pregnant women. Eur J Obstet Gynecol Reprod Biol 2004;116:152-156. (Pubitemid 39195125)
-
(2004)
European Journal of Obstetrics Gynecology and Reproductive Biology
, vol.116
, Issue.2
, pp. 152-156
-
-
Genc, M.R.1
Vardhana, S.2
Delaney, M.L.3
Onderdonk, A.4
Tuomala, R.5
Norwitz, E.6
Witkin, S.S.7
-
355
-
-
25844486051
-
Differences in inflammatory cytokine and Toll-like receptor genes and bacterial vaginosis in pregnancy
-
DOI 10.1016/j.ajog.2005.03.053, PII S0002937805004886
-
Goepfert AR, Varner M, Ward K, et al. Differences in inflammatory cytokine and Toll-like receptor genes and bacterial vaginosis in pregnancy. Am J Obstet Gynecol 2005;193:1478-1485. (Pubitemid 41395120)
-
(2005)
American Journal of Obstetrics and Gynecology
, vol.193
, Issue.4
, pp. 1478-1485
-
-
Goepfert, A.R.1
Varner, M.2
Ward, K.3
Macpherson, C.4
Klebanoff, M.5
Goldenberg, R.L.6
Mercer, B.7
Meis, P.8
Iams, J.9
Moawad, A.10
Carey, J.C.11
Leveno, K.12
Wapner, R.13
Caritis, S.N.14
Miodovnik, M.15
Sorokin, Y.16
O'Sullivan, M.J.17
Van Dorsten, J.P.18
Langer, O.19
-
356
-
-
33747159835
-
TLR4 polymorphism in Iranian patients with brucellosis
-
DOI 10.1016/j.jinf.2005.10.018, PII S0163445305003348
-
RezazadehM, Hajilooi M, Rafiei A, et al. TLR4 polymorphism in Iranian patients with brucellosis. J Infect 2006;53:206-210. (Pubitemid 44227806)
-
(2006)
Journal of Infection
, vol.53
, Issue.3
, pp. 206-210
-
-
Rezazadeh, M.1
Hajilooi, M.2
Rafiei, A.3
Haidari, M.4
Nikoopour, E.5
Kerammat, F.6
Mamani, M.7
Ranjbar, M.8
Hashemi, H.9
-
357
-
-
1442263160
-
Candida-specific interferon-gamma deficiency and toll-like receptor polymorphisms in patients with chronicmucocutaneous candidiasis
-
van der Graaf CA, Netea MG, Drenth IP, et al. Candida-specific interferon-gamma deficiency and toll-like receptor polymorphisms in patients with chronicmucocutaneous candidiasis. Neth JMed 2003;61:365-369.
-
(2003)
Neth JMed
, vol.61
, pp. 365-369
-
-
Van Der Graaf, C.A.1
Netea, M.G.2
Drenth, I.P.3
-
358
-
-
0036838272
-
Role of the toll-like receptor 4 Asp299Gly polymorphism in susceptibility to Candida albicans infection [2] (multiple letters)
-
Morre SA, Murillo LS, Spaargaren J, et al. Role of the toll-like receptor 4 Asp299Gly polymorphism in susceptibility to Candida albicans infection. J Infect Dis 2002;186:1377-1379; author reply 1379. (Pubitemid 35193023)
-
(2002)
Journal of Infectious Diseases
, vol.186
, Issue.9
, pp. 1377-1379
-
-
Morre, S.A.1
Murillo, L.S.2
Spaargaren, J.3
Fennema, H.S.A.4
Pena, A.S.5
Netea, M.G.6
Van Der Meer, J.W.M.7
Kullberg, B.J.8
-
359
-
-
33645086385
-
The Toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gram-negative and haematogenous osteomyelitis
-
Montes AH, Asensi V, Alvarez V, et al. The Toll-like receptor 4 (Asp299Gly) polymorphism is a risk factor for Gram-negative and haematogenous osteomyelitis. Clin Exp Immunol 2006;143: 404-413.
-
(2006)
Clin Exp Immunol
, vol.143
, pp. 404-413
-
-
Montes, A.H.1
Asensi, V.2
Alvarez, V.3
-
360
-
-
33746162770
-
Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinical manifestation of malaria during pregnancy
-
DOI 10.1086/505152
-
Mockenhaupt FP, Hamann L, von Gaertner C, et al. Common polymorphisms of toll-like receptors 4 and 9 are associated with the clinicalmanifestation ofmalaria during pregnancy. J Infect Dis 2006;194:184-188. (Pubitemid 44087189)
-
(2006)
Journal of Infectious Diseases
, vol.194
, Issue.2
, pp. 184-188
-
-
Mockenhaupt, F.P.1
Hamann, L.2
Von Gaertner, C.3
Bedu-Addo, G.4
Von Kleinsorgen, C.5
Schumann, R.R.6
Bienzle, U.7
-
361
-
-
0345708247
-
Variation in toll-like receptor 4 and susceptibility to group a meningococcal meningitis in Gambian children
-
DOI 10.1097/01.inf.0000095431.15606.68
-
Allen A, Obaro S, Bojang K, et al. Variation in Toll-like receptor 4 and susceptibility to group A meningococcal meningitis in Gambian children. Pediatr Infect Dis J 2003;22:1018-1019. (Pubitemid 37445083)
-
(2003)
Pediatric Infectious Disease Journal
, vol.22
, Issue.11
, pp. 1018-1019
-
-
Allen, A.1
Obaro, S.2
Bojang, K.3
Awomoyi, A.A.4
Greenwood, B.M.5
Whittle, H.6
Sirugo, G.7
Newport, M.J.8
-
362
-
-
70350236305
-
CD14 C-159T and toll-like receptor 4 Asp299Gly polymorphisms in surviving meningococcal disease patients
-
Biebl A, Muendlein A, Kazakbaeva Z, et al. CD14 C-159T and toll-like receptor 4 Asp299Gly polymorphisms in surviving meningococcal disease patients. PLoS One 2009;4:e7374.
-
(2009)
PLoS One
, vol.4
-
-
Biebl, A.1
Muendlein, A.2
Kazakbaeva, Z.3
-
363
-
-
0037947560
-
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
-
DOI 10.1073/pnas.1031605100
-
Smirnova I, Mann N, Dols A, et al. Assay of locus-specific genetic load implicates rare Tolllike receptor 4 mutations in meningococcal susceptibility. Proc Natl Acad Sci USA 2003;100: 6075-6080. (Pubitemid 36576933)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.10
, pp. 6075-6080
-
-
Smirnova, I.1
Mann, N.2
Dols, A.3
Derkx, H.H.4
Hibberd, M.L.5
Levin, M.6
Beutler, B.7
-
364
-
-
33644790835
-
Functional gene polymorphisms in aggressive and chronic periodontitis
-
DOI 10.1177/154405910508401211
-
Brett PM, Zygogianni P, Griffiths GS, et al. Functional gene polymorphisms in aggressive and chronic periodontitis. J Dent Res 2005;84:1149-1153. (Pubitemid 43827783)
-
(2005)
Journal of Dental Research
, vol.84
, Issue.12
, pp. 1149-1153
-
-
Brett, P.M.1
Zygogianni, P.2
Griffiths, G.S.3
Tomaz, M.4
Parkar, M.5
D'Aiuto, F.6
Tonetti, M.7
-
365
-
-
33646148510
-
Gingival epithelial cells heterozygous for Toll-like receptor 4 polymorphisms Asp299Gly and Thr399ile are hypo-responsive to Porphyromonas gingivalis
-
Kinane DF, Shiba H, Stathopoulou PG, et al. Gingival epithelial cells heterozygous for Toll-like receptor 4 polymorphisms Asp299Gly and Thr399ile are hypo-responsive to Porphyromonas gingivalis. Genes Immun 2006;7:190-200.
-
(2006)
Genes Immun
, vol.7
, pp. 190-200
-
-
Kinane, D.F.1
Shiba, H.2
Stathopoulou, P.G.3
-
366
-
-
33644658480
-
CD14 and TLR4 gene polymorphisms in adult periodontitis
-
DOI 10.1177/154405910508401114
-
LaineML,Morre SA,Murillo LS, et al. CD14 and TLR4 gene polymorphisms in adult periodontitis. J Dent Res 2005;84:1042-1046. (Pubitemid 43828153)
-
(2005)
Journal of Dental Research
, vol.84
, Issue.11
, pp. 1042-1046
-
-
Laine, M.L.1
Morre, S.A.2
Murillo, L.S.3
Van Winkelhoff, A.-J.4
Pena, A.S.5
-
367
-
-
4444258811
-
Gene polymorphisms in pro-inflammatory cytokines are associated with systemic inflammation in patients with severe periodontal infections
-
DOI 10.1016/j.cyto.2004.06.005, PII S1043466604001863
-
D'Aiuto F, Parkar M, Brett PM, et al. Gene polymorphisms in pro-inflammatory cytokines are associated with systemic inflammation in patients with severe periodontal infections. Cytokine 2004;28:29-34. (Pubitemid 39165618)
-
(2004)
Cytokine
, vol.28
, Issue.1
, pp. 29-34
-
-
D'Aiuto, F.1
Parkar, M.2
Brett, P.M.3
Ready, D.4
Tonetti, M.S.5
-
368
-
-
0842265493
-
Toll-like receptor (TLR) 2 and 4 mutations in periodontal disease
-
DOI 10.1111/j.1365-2249.2004.02383.x
-
FolwacznyM, Glas J, Torok HP, et al. Toll-like receptor (TLR) 2 and 4mutations in periodontal disease. Clin Exp Immunol 2004;135:330-335. (Pubitemid 38177975)
-
(2004)
Clinical and Experimental Immunology
, vol.135
, Issue.2
, pp. 330-335
-
-
Folwaczny, M.1
Glas, J.2
Torok, H.-P.3
Limbersky, O.4
Folwaczny, C.5
-
370
-
-
79551479872
-
Toll-like receptor 4 gene (TLR4), but not TLR2, polymorphisms modify the risk of tonsillar disease due to Streptococcus pyogenes and Haemophilus influenzae
-
Liadaki K, Petinaki E, Skoulakis C, et al. Toll-like receptor 4 gene (TLR4), but not TLR2, polymorphisms modify the risk of tonsillar disease due to Streptococcus pyogenes and Haemophilus influenzae. Clin Vaccine Immunol 2011;18:217-222.
-
(2011)
Clin Vaccine Immunol
, vol.18
, pp. 217-222
-
-
Liadaki, K.1
Petinaki, E.2
Skoulakis, C.3
-
371
-
-
33750839061
-
Polymorphisms within inflammatory genes and colorectal cancer
-
Landi S, Gemignani F, Bottari F, et al. Polymorphisms within inflammatory genes and colorectal cancer. J Negat Results Biomed 2006;5:15.
-
(2006)
J Negat Results Biomed
, vol.5
, pp. 15
-
-
Landi, S.1
Gemignani, F.2
Bottari, F.3
-
372
-
-
70350588993
-
Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer
-
Tsilidis KK, Helzlsouer KJ, Smith MW, et al. Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer. Cancer Causes Control 2009;20:1739-1751.
-
(2009)
Cancer Causes Control
, vol.20
, pp. 1739-1751
-
-
Tsilidis, K.K.1
Helzlsouer, K.J.2
Smith, M.W.3
-
373
-
-
33745176199
-
Polymorphisms in innate immunity genes and risk of non-Hodgkin lymphoma
-
DOI 10.1111/j.1365-2141.2006.06141.x
-
Forrest MS, Skibola CF, Lightfoot TJ, et al. Polymorphisms in innate immunity genes and risk of non-Hodgkin lymphoma. Br J Haematol 2006;134:180-183. (Pubitemid 43893909)
-
(2006)
British Journal of Haematology
, vol.134
, Issue.2
, pp. 180-183
-
-
Forrest, M.S.1
Skibola, C.F.2
Lightfoot, T.J.3
Bracci, P.M.4
Willett, E.V.5
Smith, M.T.6
Holly, E.A.7
Roman, E.8
-
374
-
-
58149147611
-
Association of polymorphisms of NOD2, TLR4 and CD14 genes with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma
-
Ture-Ozdemir F, Gazouli M, Tzivras M, et al. Association of polymorphisms of NOD2, TLR4 and CD14 genes with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma. Anticancer Res 2008;28:3697-3700.
-
(2008)
Anticancer Res
, vol.28
, pp. 3697-3700
-
-
Ture-Ozdemir, F.1
Gazouli, M.2
Tzivras, M.3
-
375
-
-
33748136551
-
Heterozygous Thr 135 Ala polymorphism at leucine-rich repeat (LRR) in genomic DNA of toll-like receptor 4 in patients with poorly-differentiated gastric adenocarcinomas
-
Ohara T, Morishita T, Suzuki H, Hibi T. Heterozygous Thr 135 Ala polymorphism at leucine-rich repeat (LRR) in genomic DNA of toll-like receptor 4 in patients with poorly-differentiated gastric adenocarcinomas. Int JMolMed 2006;18:59-63.
-
(2006)
Int JMolMed
, vol.18
, pp. 59-63
-
-
Ohara, T.1
Morishita, T.2
Suzuki, H.3
Hibi, T.4
-
376
-
-
55449103507
-
Toll-like receptor 4 Asp299Gly andThr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes
-
Santini D, Angeletti S, Ruzzo A, et al. Toll-like receptor 4 Asp299Gly andThr399Ile polymorphisms in gastric cancer of intestinal and diffuse histotypes. Clin Exp Immunol 2008;154:360-364.
-
(2008)
Clin Exp Immunol
, vol.154
, pp. 360-364
-
-
Santini, D.1
Angeletti, S.2
Ruzzo, A.3
-
377
-
-
33947304959
-
A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors
-
DOI 10.1053/j.gastro.2006.12.026, PII S001650850602676X
-
Hold GL, Rabkin CS, Chow WH, et al. A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. Gastroenterology 2007;132:905-912. (Pubitemid 46440859)
-
(2007)
Gastroenterology
, vol.132
, Issue.3
, pp. 905-912
-
-
Hold, G.L.1
Rabkin, C.S.2
Chow, W.3
Smith, M.G.4
Gammon, M.D.5
Risch, H.A.6
Vaughan, T.L.7
McColl, K.E.L.8
Lissowska, J.9
Zatonski, W.10
Schoenberg, J.B.11
Blot, W.J.12
Mowat, N.A.G.13
Fraumeni Jr., J.F.14
El-Omar, E.M.15
-
378
-
-
22044445110
-
Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma
-
DOI 10.1080/1042819050086451
-
Hellmig S, FischbachW,Goebeler-KolveME, et al. Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma. Leuk Lymphoma 2005;46:869-872. (Pubitemid 40965398)
-
(2005)
Leukemia and Lymphoma
, vol.46
, Issue.6
, pp. 869-872
-
-
Hellmig, S.1
Fischbach, W.2
Goebeler-Kolve, M.-E.3
Folsch, U.R.4
Hampe, J.5
Schreiber, S.6
-
379
-
-
36849069469
-
Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions
-
DOI 10.1016/j.humimm.2007.10.006, PII S0198885907004582
-
Achyut BR, Ghoshal UC, Moorchung N, Mittal B. Association of Toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions. Hum Immunol 2007;68:901-907. (Pubitemid 350235728)
-
(2007)
Human Immunology
, vol.68
, Issue.11
, pp. 901-907
-
-
Achyut, B.R.1
Ghoshal, U.C.2
Moorchung, N.3
Mittal, B.4
-
380
-
-
58449135482
-
Toll-like receptor 4 +3725 G/C polymorphism, Helicobacter pylori seropositivity, and the risk of gastric atrophy and gastric cancer in Japanese
-
Hishida A, Matsuo K, Goto Y, et al. Toll-like receptor 4 +3725 G/C polymorphism, Helicobacter pylori seropositivity, and the risk of gastric atrophy and gastric cancer in Japanese. Helicobacter 2009;14:47-53.
-
(2009)
Helicobacter
, vol.14
, pp. 47-53
-
-
Hishida, A.1
Matsuo, K.2
Goto, Y.3
-
381
-
-
77950526750
-
TLR4 and NOD2/CARD15 genetic polymorphisms and their possible role in gastric carcinogenesis
-
Rigoli L, Di Bella C, Fedele F, et al. TLR4 and NOD2/CARD15 genetic polymorphisms and their possible role in gastric carcinogenesis. Anticancer Res 2010;30:513-517.
-
(2010)
Anticancer Res
, vol.30
, pp. 513-517
-
-
Rigoli, L.1
Di Bella, C.2
Fedele, F.3
-
382
-
-
8444235603
-
Sequence Variants of Toll-Like Receptor 4 Are Associated with Prostate Cancer Risk: Results from the CAncer Prostate in Sweden Study
-
DOI 10.1158/0008-5472.CAN-03-3280
-
Zheng SL, Augustsson-Balter K, Chang B, et al. Sequence variants of toll-like receptor 4 are associated with prostate cancer risk: results from the CAncer Prostate in Sweden Study. Cancer Res 2004;64:2918-2922. (Pubitemid 38500633)
-
(2004)
Cancer Research
, vol.64
, Issue.8
, pp. 2918-2922
-
-
Zheng, S.L.1
Augustsson-Balter, K.2
Chang, B.3
Hedelin, M.4
Li, L.5
Adami, H.-O.6
Bensen, J.7
Li, G.8
Johnasson, J.-E.9
Turner, A.R.10
Adams, T.S.11
Meyers, D.A.12
Isaacs, W.B.13
Xu, J.14
Gronberg, H.15
-
383
-
-
29244441698
-
Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer
-
DOI 10.1158/0008-5472.CAN-05-2078
-
Chen YC,Giovannucci E, LazarusR, et al. Sequence variants of Toll-like receptor 4 and susceptibility to prostate cancer. Cancer Res 2005;65:11771-11778. (Pubitemid 41821739)
-
(2005)
Cancer Research
, vol.65
, Issue.24
, pp. 11771-11778
-
-
Chen, Y.-C.1
Giovannucci, E.2
Lazarus, R.3
Kraft, P.4
Ketkar, S.5
Hunter, D.J.6
-
384
-
-
65549107763
-
Association of IL10 and other immune response-and obesity-related genes with prostate cancer in CLUE II
-
Wang MH, Helzlsouer KJ, Smith MW, et al. Association of IL10 and other immune response-and obesity-related genes with prostate cancer in CLUE II. Prostate 2009;69:874-885.
-
(2009)
Prostate
, vol.69
, pp. 874-885
-
-
Wang, M.H.1
Helzlsouer, K.J.2
Smith, M.W.3
-
385
-
-
33847755024
-
Toll-like receptor 4 genetic variation and advanced prostate cancer risk
-
DOI 10.1158/1055-9965.EPI-06-0429
-
Cheng I, Plummer SJ, CaseyG,Witte JS. Toll-like receptor 4 genetic variation and advanced prostate cancer risk. Cancer Epidemiol Biomarkers Prev 2007;16:352-355. (Pubitemid 46383358)
-
(2007)
Cancer Epidemiology Biomarkers and Prevention
, vol.16
, Issue.2
, pp. 352-355
-
-
Cheng, I.1
Plummer, S.J.2
Casey, G.3
Witte, J.S.4
-
386
-
-
64549116737
-
The association between Toll-like receptor 4 (TLR4) polymorphisms and the risk of prostate cancer in Korean men
-
Song J, KimDY, KimCS, et al.The association between Toll-like receptor 4 (TLR4) polymorphisms and the risk of prostate cancer in Korean men. Cancer Genet Cytogenet 2009;190:88-92.
-
(2009)
Cancer Genet Cytogenet
, vol.190
, pp. 88-92
-
-
Song, J.1
Kim, D.Y.2
Kim, C.S.3
-
387
-
-
78649750164
-
The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: Results fromthe TULIP and METSIM Studies
-
Weyrich P, Staiger H, Stancakova A, et al.The D299G/T399I Toll-like receptor 4 variant associates with body and liver fat: results fromthe TULIP and METSIM Studies. PLoS One 2010;5:e13980.
-
(2010)
PLoS One
, vol.5
-
-
Weyrich, P.1
Staiger, H.2
Stancakova, A.3
-
388
-
-
84859845998
-
A TLR5 (g.1174C>T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia
-
Sampath V, Garland JS, LeM, et al. A TLR5 (g.1174C>T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia. Pediatr Pulmonol 2012;47:460-468.
-
(2012)
Pediatr Pulmonol
, vol.47
, pp. 460-468
-
-
Sampath, V.1
Garland, J.S.2
Le, M.3
-
389
-
-
36148966588
-
Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma
-
DOI 10.1182/blood-2007-05-088682
-
Cerhan JR, Ansell SM, Fredericksen ZS, et al. Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma. Blood 2007;110:4455-4463. (Pubitemid 351377812)
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4455-4463
-
-
Cerhan, J.R.1
Ansell, S.M.2
Fredericksen, Z.S.3
Kay, N.E.4
Liebow, M.5
Call, T.G.6
Dogan, A.7
Cunningham, J.M.8
Wang, A.H.9
Liu-Mares, W.10
Macon, W.R.11
Jelinek, D.12
Witzig, T.E.13
Habermann, T.M.14
Slager, S.L.15
-
390
-
-
78650214156
-
Hodgkin disease risk: Role of genetic polymorphisms and gene-gene interactions in inflammation pathway genes
-
Monroy CM, Cortes AC, Lopez MS, et al. Hodgkin disease risk: role of genetic polymorphisms and gene-gene interactions in inflammation pathway genes.Mol Carcinog 2011;50:36-46.
-
(2011)
Mol Carcinog
, vol.50
, pp. 36-46
-
-
Monroy, C.M.1
Cortes, A.C.2
Lopez, M.S.3
-
391
-
-
79951873674
-
Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis
-
Sahingur SE, Xia XJ, Gunsolley J, et al. Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis. J Periodontal Res 2011;46:184-192.
-
(2011)
J Periodontal Res
, vol.46
, pp. 184-192
-
-
Sahingur, S.E.1
Xia, X.J.2
Gunsolley, J.3
-
392
-
-
79960840054
-
Polymorphisms in the toll-like receptor 9 gene associated with sepsis andmultiple organ dysfunction aftermajor blunt trauma
-
Chen KH, Zeng L, GuW, et al. Polymorphisms in the toll-like receptor 9 gene associated with sepsis andmultiple organ dysfunction aftermajor blunt trauma. Br J Surg 2011;98:1252-1259.
-
(2011)
Br J Surg
, vol.98
, pp. 1252-1259
-
-
Chen, K.H.1
Zeng, L.2
Gu, W.3
-
393
-
-
81555195206
-
The (-1486T/C) promoter polymorphism of the TLR-9 gene is associated with end-stage knee osteoarthritis in a Chinese population
-
Su SL, Yang HY, Lee CH, et al.The (-1486T/C) promoter polymorphism of the TLR-9 gene is associated with end-stage knee osteoarthritis in a Chinese population. J Orthop Res 2012;30:9-14.
-
(2012)
J Orthop Res
, vol.30
, pp. 9-14
-
-
Su, S.L.1
Yang, H.Y.2
Lee, C.H.3
-
394
-
-
61449167212
-
CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations
-
Hold GL, Rabkin CS, GammonMD, et al. CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations. Eur J Cancer Prev 2009;18:117-119.
-
(2009)
Eur J Cancer Prev
, vol.18
, pp. 117-119
-
-
Hold, G.L.1
Rabkin, C.S.2
Gammon, M.D.3
-
395
-
-
74049146800
-
Polymorphisms and haplotypes in TLR9 andMYD88 are associated with the development of Hodgkin's lymphoma: A candidate-gene association study
-
Mollaki V, Georgiadis T, Tassidou A, et al. Polymorphisms and haplotypes in TLR9 andMYD88 are associated with the development of Hodgkin's lymphoma: a candidate-gene association study. J HumGenet 2009;54:655-659.
-
(2009)
J HumGenet
, vol.54
, pp. 655-659
-
-
Mollaki, V.1
Georgiadis, T.2
Tassidou, A.3
-
396
-
-
80053385384
-
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
-
Sklar P, Ripke S, Scott LJ, et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet 2011;43:977-983.
-
(2011)
Nat Genet
, vol.43
, pp. 977-983
-
-
Sklar, P.1
Ripke, S.2
Scott, L.J.3
-
397
-
-
80052607652
-
The T-1237C polymorphism of the Toll-like receptor-9 gene is associatedwith chronic kidney disease in aHanChinese population
-
Lu KC, Yang HY, Lin YF, et al.The T-1237C polymorphism of the Toll-like receptor-9 gene is associatedwith chronic kidney disease in aHanChinese population. Tohoku J ExpMed 2011;225:109-116.
-
(2011)
Tohoku J ExpMed
, vol.225
, pp. 109-116
-
-
Lu, K.C.1
Yang, H.Y.2
Lin, Y.F.3
-
398
-
-
31344475699
-
Combined carriership of TLR9 - 1237C and CD14 - 260T alleles enhances the risk of developing chronic relapsing pouchitis
-
Lammers KM, Ouburg S, Morre SA, et al. Combined carriership of TLR9-1237C and CD14-260T alleles enhances the risk of developing chronic relapsing pouchitis. World J Gastroenterol 2005;11:7323-7329. (Pubitemid 43137684)
-
(2005)
World Journal of Gastroenterology
, vol.11
, Issue.46
, pp. 7323-7329
-
-
Lammers, K.M.1
Ouburg, S.2
Morre, S.A.3
Crusius, J.B.A.4
Gionchetti, P.5
Rizzelo, F.6
Morselli, C.7
Caramelli, E.8
Conte, R.9
Poggioli, G.10
Campieri, M.11
Pena, A.S.12
-
399
-
-
77952061153
-
Risk ofmeningioma and common variation in genes related to innate immunity
-
Rajaraman P, Brenner AV,Neta G, et al. Risk ofmeningioma and common variation in genes related to innate immunity. Cancer Epidemiol Biomarkers Prev 2010;19:1356-1361.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 1356-1361
-
-
Rajaraman, P.1
Brenner, A.V.2
Neta, G.3
-
400
-
-
63449136073
-
Common variants at ten loci influence QT interval duration in the QTGEN Study
-
Newton-Cheh C, Eijgelsheim M, Rice KM, et al. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet 2009;41:399-406.
-
(2009)
Nat Genet
, vol.41
, pp. 399-406
-
-
Newton-Cheh, C.1
Eijgelsheim, M.2
Rice, K.M.3
-
401
-
-
77952887426
-
Genome-wide association study identifies five new breast cancer susceptibility loci
-
Turnbull C, Ahmed S, Morrison J, et al. Genome-wide association study identifies five new breast cancer susceptibility loci. Nat Genet 2010;42:504-507.
-
(2010)
Nat Genet
, vol.42
, pp. 504-507
-
-
Turnbull, C.1
Ahmed, S.2
Morrison, J.3
-
402
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
DOI 10.1038/nature05887, PII NATURE05887
-
Easton DF, Pooley KA, Dunning AM, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007;447:1087-1093. (Pubitemid 47014426)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.P.4
Thompson, D.5
Ballinger, D.G.6
Struewing, J.P.7
Morrison, J.8
Field, H.9
Luben, R.10
Wareham, N.11
Ahmed, S.12
Healey, C.S.13
Bowman, R.14
Meyer, K.B.15
Haiman, C.A.16
Kolonel, L.K.17
Henderson, B.E.18
Le Marchand, L.19
Brennan, P.20
Sangrajrang, S.21
Gaborieau, V.22
Odefrey, F.23
Shen, C.-Y.24
Wu, P.-E.25
Wang, H.-C.26
Eccles, D.27
Evans, D.G.28
Peto, J.29
Fletcher, O.30
Johnson, N.31
Seal, S.32
Stratton, M.R.33
Rahman, N.34
Chenevix-Trench, G.35
Bojesen, S.E.36
Nordestgaard, B.G.37
Axelsson, C.K.38
Garcia-Closas, M.39
Brinton, L.40
Chanock, S.41
Lissowska, J.42
Peplonska, B.43
Nevanlinna, H.44
Fagerholm, R.45
Eerola, H.46
Kang, D.47
Yoo, K.-Y.48
Noh, D.-Y.49
Ahn, S.-H.50
Hunter, D.J.51
Hankinson, S.E.52
Cox, D.G.53
Hall, P.54
Wedren, S.55
Liu, J.56
Low, Y.-L.57
Bogdanova, N.58
Schurmann, P.59
Dork, T.60
Tollenaar, R.A.E.M.61
Jacobi, C.E.62
Devilee, P.63
Klijn, J.G.M.64
more..
-
403
-
-
79951827439
-
Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy
-
Stanescu HC, Arcos-BurgosM,Medlar A, et al. Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy. N Engl JMed 2011;364:616-626.
-
(2011)
N Engl JMed
, vol.364
, pp. 616-626
-
-
Stanescu, H.C.1
Arcos-Burgos, M.2
Medlar, A.3
-
404
-
-
80053173074
-
Genetic variants in LPLOASL and TOMM40/APOEC1-C2-C4 genes are associated with multiple cardiovascular-related traits
-
MiddelbergRP, FerreiraMA,Henders AK, et al.Genetic variants in LPL,OASL and TOMM40/APOEC1-C2-C4 genes are associated with multiple cardiovascular- related traits. BMC Med Genet 2011;12:123.
-
(2011)
BMC Med Genet
, vol.12
, pp. 123
-
-
Middelberg, R.P.1
Ferreira, M.A.2
Henders, A.K.3
-
405
-
-
84863255226
-
A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants
-
Tao S,Wang Z, Feng J, et al. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. Carcinogenesis 2012;33:598-603.
-
(2012)
Carcinogenesis
, vol.33
, pp. 598-603
-
-
Tao, S.1
Wang, Z.2
Feng, J.3
-
406
-
-
52949091918
-
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
-
Kugathasan S, Baldassano RN, Bradfield JP, et al. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nat Genet 2008;40:1211-1215.
-
(2008)
Nat Genet
, vol.40
, pp. 1211-1215
-
-
Kugathasan, S.1
Baldassano, R.N.2
Bradfield, J.P.3
|