Elevated plasma fibrinogen, psychological distress, antidepressant use, and hospitalization with depression: Two large population-based studies

Psychoneuroendocrinology

Volumn 38, Issue 5, 2013, Pages 638-647

  Wium Andersen, Marie Kim ^a,c   Ørsted, David Dynnes ^a,c   Nordestgaard, Børge Grønne ^a,b,c  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^b BISPEBJERG HOSPITAL   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Acute phase protein; Depression; Fibrinogen; Low grade inflammation; Psychological distress

Indexed keywords

ANTIDEPRESSANT AGENT; FIBRINOGEN; NORADRENALIN UPTAKE INHIBITOR; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DENMARK; DEPRESSION; DISEASE ASSOCIATION; DISTRESS SYNDROME; DRUG USE; FEMALE; FIBRINOGEN BLOOD LEVEL; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PRESCRIPTION; PRIORITY JOURNAL; PROSPECTIVE STUDY;

ADULT; AGED; AGED, 80 AND OVER; ANTIDEPRESSIVE AGENTS; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER; FEMALE; FIBRINOGEN; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; STRESS, PSYCHOLOGICAL; UP-REGULATION; YOUNG ADULT;

EID: 84876090335     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2012.08.006     Document Type: Article

References (33)

1. Baune B.T., Neuhauser H., Ellert U., Berger K. The role of the inflammatory markers ferritin, transferrin and fibrinogen in the relationship between major depression and cardiovascular disorders - The German Health Interview and Examination Survey. Acta Psychiatr. Scand. 2010, 121:135-142.
2. Clarke R., Shipley M., Lewington S., Youngman L., Collins R., Marmot M., Peto R. Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies. Am. J. Epidemiol. 1999, 150:341-353.
3. Danish National Board of Health Sundhedsstyrelsens Referenceprogram for Unipolar Depression hos voksne 2007 2007, Sundhedsstyrelsen, Copenhagen.
4. de Moerloose P., Boehlen F., Neerman-Arbez M. Fibrinogen and the risk of thrombosis. Semin. Thromb. Hemost. 2010, 36:7-17.
5. Doulalas A.D., Rallidis L.S., Gialernios T., Moschonas D.N., Kougioulis M.N., Rizos I., et al. Association of depressive symptoms with coagulation factors in young healthy individuals. Atherosclerosis 2006, 186:121-125.
6. Dowlati Y., Herrmann N., Swardfager W., Liu H., Sham L., Reim E.K., Lanctôt K.L. A meta-analysis of cytokines in major depression. Biol. Psychiatry 2010, 67:446-457.
7. Gabay C., Kushner I. Acute-phase proteins and other systemic responses to inflammation. N. Engl. J. Med. 1999, 340:448-454.
8. Gardarsdottir H., Heerdink E.R., van Dijk L., Egberts A.C.G. Indications for antidepressant drug prescribing in general practice in the Netherlands. J. Affect. Disord. 2007, 98:109-115.
9. Geiser F., Conrad R., Imbierowicz K., Meier C., Liedtke R., Klingmüller D., et al. Coagulation activation and fibrinolysis impairment are reduced in patients with anxiety and depression when medicated with serotonergic antidepressants. Psychiatry Clin. Neurosci. 2011, 65:518-525.
10. Goldman-Mellor S., Brydon L., Steptoe A. Psychological distress and circulating inflammatory markers in healthy young adults. Psychol. Med. 2010, 40:2079-2087.
11. Hansen D.G., Vach W., Rosholm J.U., Søndergaard J., Gram L.F., Kragstrup J. Early discontinuation of antidepressants in general practice: association with patient and prescriber characteristics. Fam. Pract. 2004, 21:623-629.
12. Haroon E., Raison C.L., Miller A.H. Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior. Neuropsychopharmacology Reviews 2012, 37:137-162.
13. Howren M.B., Lamkin D.M., Suls J. Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom. Med. 2009, 71:171-186.
14. Jensen T., Kierulf P., Sandset P.M., Klingenberg O., Joø G.B., Godal H.C., Skjønsberg O.H. Fibrinogen and fibrin induce synthesis of proinflammatory cytokines from isolated peripheral blood mononuclear cells. Thromb. Haemost. 2007, 20:822-829.
15. Kamstrup P.R., Benn M., Tybjaerg-Hansen A., Nordestgaard B.G. Extreme lipoprotein(a) levels and risk of myocardial infarction in the general population: the Copenhagen City Heart Study. Circulation 2008, 117:176-184.
16. Kaptoge S., White I.R., Thompson S.G., Wood A.M., Lewington S., Lowe G.D.O., Danesh J. Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: individual participant meta-analysis of 154,211 adults in 31 prospective studies: the fibrinogen studies collaboration. Am. J. Epidemiol. 2007, 166:867-879.
17. Knuiman M.W., Divitini M.L., Buzas J.S., Fitzgerald P.E. Adjustment for regression dilution in epidemiological regression analyses. Ann. Epidemiol. 1998, 8:56-63.
18. Kop W.J., Gottdiener J.S., Tangen C.M., Fried L.P., McBurnie M.A., Walston J., et al. Inflammation and coagulation factors in persons >65 years of age with symptoms of depression but without evidence of myocardial ischemia. Am. J. Cardiol. 2002, 89:419-424.
19. Kop W.J., Stein P.K., Tracy R.P., Barzilay J.I., Schulz R., Gottdiener J.S. Autonomic nervous system dysfunction and inflammation contribute to the increased cardiovascular mortality risk associated with depression. Psychosom. Med. 2010, 72:626-635.
20. Lahlou-Laforet K., Alhenc-Gelas M., Pornin M., Bydlowski S., Seigneur E., Benetos A., et al. Relation of depressive mood to plasminogen activator inhibitor, tissue plasminogen activator, and fibrinogen levels in patients with versus without coronary heart disease. Am. J. Cardiol. 2006, 97:1287-1291.
21. Maes M., Delange J., Ranjan R., Meltzer H.Y., Desnyder R., Cooremans W., Sharpé S. Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs. Psychiatry Res. 1997, 66:1-11.
22. Matthews K.A., Schott L.L., Bromberger J., Cyranowski J., Everson-Rose S.A., Sowers M.F. Associations between depressive symptoms and inflammatory/hemostatic markers in women during the menopausal transition. Psychosom. Med. 2007, 69:124-130.
23. Nabi H., Singh-Manoux A., Shipley M., Gimeno D., Marmot M.G., Kivimaki M. Do psychological factors affect inflammation and incident coronary heart disease: the Whitehall II Study. Arterioscler. Thromb. Vasc. Biol. 2008, 28:1398-1406.
24. Nordestgaard B.G., Benn M., Schnohr P., Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007, 298:299-308.
25. Ohayon M.M., Priest R.G., Guilleminault C., Caulet M. The prevalence of depressive disorders in the United Kingdom. Biol. Psychiatry 1999, 45:300-307.
26. Panagiotakos D.B., Pitsavos C., Chrysohoou C., Tsetsekou E., Papageorgiou C., Christodoulou G., Stefanadis C. Inflammation, coagulation, and depressive symptomatology in cardiovascular disease-free people; the ATTICA study. Eur. Heart J. 2004, 25:492-499.
27. Raison C.L., Miller A.H. Is depression an inflammatory disorder?. Curr. Psychiatry Rep. 2011, 13:467-475.
28. Steptoe A., Kunz-Ebrecht S.R., Owen N. Lack of association between depressive symptoms and markers of immune and vascular inflammation in middle-aged men and women. Psychol. Med. 2003, 33:667-674.
29. von Kanël R., Mills P.J., Fainman C., Dimsdale J.E. Effects of psychological stress and psychiatric disorders on blood coagulation and fibrinolysis: a biobehavioral pathway to coronary artery disease?. Psychosom. Med. 2001, 63:531-544.
30. Wium-Andersen, M.K., Ørsted, D.D., Nordestgaard, B.G. Association between elevated plasma fibrinogen and psychological distress and depression in 73,367 individuals from the general population. Mol. Psychiatry, in press.
31. Whooley M.A., Caska C.M., Hendrickson B.E., Rourke M.A., Ho J., Ali S. Depression and inflammation in patients with coronary heart disease: findings from the Heart and Soul Study. Biol. Psychiatry 2007, 62:314-320.
32. World Health Organisation What are the Most Effective Diagnostic and Therapeutic Strategies for the Management of Depression in Specialist Care? 2005, WHO, Copenhagen. 1st ed.
33. World Health Organisation Collaborating Center for Drug Statistics Methodology Guidelines for ATC Classification and DDD Assignment 2011, Norwegian Institute of Public Health, Oslo. 14th ed.