Hepatoprotective activity of methanolic extract of Rhyncosia beddomei baker leaves against carbon tetrachloride induced hepatotoxicity

Journal of Applied Pharmaceutical Science

Volumn 2, Issue 8, 2012, Pages 146-149

  Ashoka Babu, V L ^a   Arunachalam, G ^b   Jayaveera, K N ^c   Madhavan, V ^a   Banu, Shanaz ^d  

^a M S RAMAIAH UNIVERSITY OF APPLIED SCIENCES   (India)

^b PGP College of Pharmaceutical Science and Research Institute   (India)

^c JNTUA COLLEGE OF ENGINEERING   (India)

^d Kumarswamy Layout   (India)

Author keywords

ALP; Biochemical markers; Hepatoprotective activity; Rhyncosia beddomei; SGOT; SGPT

Indexed keywords

EID: 84876060283     PISSN: None     EISSN: 22313354     Source Type: Journal    
DOI: 10.7324/JAPS.2012.2825     Document Type: Article

References (21)

1. Bergmeyer HU, Bowers GN, Horder M, Moss DW. Provisional recommendations on IFCC methods for the measurement of catalytic concentrations of enzymes. Clin.Chem, 1977; 23: 887-899.
2. Bessey OA, Lowry O, Brock MJ. A method for the rapid determination of alkaline phospatase with 5 cubic milliliters of serum. Biol. Chem.1946; 164: 321-329.
3. Bucolo G and David M. IFCC methods for the measurement of catalytic concentrations of enzymes. Clin.Chem; 1973; 19: 476.
4. Chetty MK, Sivaji K, Rao TK. Flowering plants of Chittoor district, Andhra Pradesh, India. Students Offset Printers; Tirupati. 2008; :256.
5. Dash DK., Yeligar VC., Nayak SS., Ghosh T., Rajalingam D., Maiti BC., Maity TK. Evaluation of hepato protective and antioxidant activity of Ichnocarpus frutescens(Linn) R.Br.on Paracetamol induced hepato toxicity in rats. Trop J Pharm Res. 2007; 6(3): 755-765.
6. nd ed, New Delhi. Vallabh prakashan. 2002; 447-449.
7. th edition, New Delhi. Jaypee Brothers Medical Publishers (p) ltd. 2002; 569-630.
8. nd edition. 1974.
9. Heyes JR, Condie LW, Brozelleca JF. Acute 14 days repeated dosage and 90 days subchronic toxicity studies of CCl4 in CDI mice. Fundamentals Appl. Toxicol. 1986; 7: 454.
10. Kind PRN, King EJ. Estimation of Plasmsa phosphates by determination of hydrolyzed Phenol with Antipyrine. J. Clinn. Pathol. 1954; 7: 322-330.
11. Kokate CK. Practical Pharmacognosy. New Delhi. Vallabh Prakashan. 1999; 107-121.
12. Krishna KL, Mruthunjaya K, Jagruthi Patel A. Antioxidant and Hepatoprotective Potential of Stem methanolic extract of Justicia gendurosa Burm. International Journal of Pharmacology. 2010; 6(2): 72- 80.
13. Nanji AA., Jokelainen K., Rahemtulla, A., Thomas P., Tipoe GL. Increased sevirity of ethanolic liver injury in female rats: role of oxidative stress, endotoxin and chemokines. Am. J. Physiol. Gastrointest. Liver Physiol. 2001; 281: 1348-1356.
14. Pearlman FC, Lee RT. Detection and measurement of total bilirubin in serum with use of surfactants as solubilizing agents. Clin. Chem. 1974; 20: 447-453.
15. Ramachandra setty S., Absar Ahmed Quereshi., Viswanath swamy AHM., Tushar patil, Prakash T., Prabhu K., Veran Goud A. Hepato protective activity of Calotrophis Procera flowers against Paracetamol induced hepato toxicity in rats. Fitoterapia. 2007; 78: 451- 454.
16. Rastogi RP, Mehrotra BN. Compendium of Indian Medicinal Plants. Lucknow, CDRI and New Delhi; NISC. 1970-1979; 2:288.
17. Sangameswaran B, Reddy TC, Jayakar B. Hepatoprotective effect of leaf extract of Andrographis lineata Nees on liver damage caused by Carbon tetra chloridein rats. Phytotherapy research. 2008; 22(1): 124- 126.
18. Subramonioum A, Evans DA, Rajashekaran SP. Hepato protective activity of Trichopus Zeylanica extract against Paracetamol induced damage in rats,. Ind J Expt Biol,. 1998; 36: 385-389.
19. Vadivu R, Krithika A, Dedeepya P, Shoeb N, Lakshmi KS. Evaluation of Hepatoprotective activity of the fruits of Coccinia grandis Linn. International Journal of Health Research. 2008; 1(3): 163-168.
20. Vijayan P., Prashanth HC., Vijayaraj P., Dhanaraj SA., Badami S., Suresh B. Hepatoprotective effect of the total alkaloid fraction of Solanum pseudocapsicum leaves. Pharm.Biol. 2003; 41: 443-448.
21. th 2001 Dec.