Video-rate functional photoacoustic microscopy at depths

Journal of Biomedical Optics

Volumn 17, Issue 10, 2012, Pages

  Wang, Lidai ^a   Maslov, Konstantin ^a   Xing, Wenxin ^a   Garcia Uribe, Alejandro ^a   Wang, Lihong V ^a  

^a WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

Cardio vascular hemodynamics; Fast scanning; Oxygen dynamics; Photoacoustic imaging; Photoacoustic microscopy; Photoacoustic tomography; Voice coil

Indexed keywords

ACOUSTIC MICROSCOPY; ANIMAL; ANOXIA; ARTICLE; BLOOD; BRAIN; COMPUTER SIMULATION; EAR; ECHOENCEPHALOGRAPHY; ECHOGRAPHY; HYPEROXIA; INSTRUMENTATION; METHODOLOGY; MICROVASCULATURE; MONTE CARLO METHOD; MOUSE; NUDE MOUSE; PHOTOACOUSTICS; VASCULARIZATION; VIDEO MICROSCOPY;

ANIMALS; ANOXIA; BRAIN; COMPUTER SIMULATION; EAR; ECHOENCEPHALOGRAPHY; HYPEROXIA; MICE; MICE, NUDE; MICROSCOPY, ACOUSTIC; MICROSCOPY, VIDEO; MICROVESSELS; MONTE CARLO METHOD; PHOTOACOUSTIC TECHNIQUES;

EID: 84876037245     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.JBO.17.10.106007     Document Type: Article

References (20)

1. L. V. Wang and S. Hu, Photoacoustic tomography: In vivo imaging from organelles to organs, Science 335(6075), 1458-1462 (2012).
2. X. Wang et al., Noninvasive laser-induced photoacoustic tomography for structural and functional in vivo imaging of the brain, Nat. Biotech. 21(7), 803-806 (2003). (Pubitemid 36791400)
3. H. F. Zhang et al., Functional photoacoustic microscopy for highresolution and noninvasive in vivo imaging, Nat. Biotech. 24(7), 848-851 (2006). (Pubitemid 44086627)
4. K. H. Song and L. V. Wang, Deep reflection-mode photoacoustic imaging of biological tissue, J. Biomed. Opt. 12(6), 060503 (2007).
5. L. Meng-Lin et al., Simultaneous molecular and hypoxia imaging of brain tumors using spectroscopic photoacoustic tomography, Proc. IEEE 96(3), 481-489 (2008).
6. A. De La Zerda et al., Carbon nanotubes as photoacoustic molecular imaging agents in living mice, Nat. Nano. 3(9), 557-562 (2008).
7. C. Kim et al., Deeply penetrating in vivo photoacoustic imaging using a clinical ultrasound array system, Biomed. Opt. Express 1(1), 278-284 (2010).
8. G. S. Filonov et al., Deep-tissue photoacoustic tomography of a genetically encoded near-infrared fluorescent probe, Angewandte Chemie International Edition 51(6), 1448-1451 (2012).
9. R. J. Zemp et al., Realtime photoacoustic microscopy in vivo with a 30-MHz ultrasound array transducer, Opt. Express 16(11), 7915-7928 (2008). (Pubitemid 351775002)
10. J. Gamelin et al., A real-time photoacoustic tomography system for small animals, Opt. Express 17(13), 10489-10498 (2009).
11. L. Song, K. Maslov, and L. V.Wang, Section-illumination photoacoustic microscopy for dynamic 3D imaging of microcirculation in vivo, Opt. Lett. 35(9), 1482-1484 (2010).
12. T. Harrison et al., Combined photoacoustic and ultrasound biomicroscopy, Opt. Express 17(24), 22041-22046 (2009).
13. K. Maslov, G. Stoica, and L. V. Wang, In vivo dark-field reflectionmode photoacoustic microscopy, Opt. Lett. 30(6), 625-627 (2005). (Pubitemid 40402333)
14. W. S. Erich, M. Konstantin, and V. W. Lihong, Noninvasive, in vivo imaging of the mouse brain using photoacoustic microscopy, J. Appl. Phys. 105(10), 102027 (2009).
15. American National Standards Institute, American national standard for the safe use of lasers, ANSI Standard Z136.1 (2000).
16. C. Zhang et al., Reflection-mode submicron-resolution in vivo photoacoustic microscopy, J. Biomed. Opt. 17(2), 020501 (2012).
17. L. Jan et al., Quantitative spatially resolved measurement of tissue chromophore concentrations using photoacoustic spectroscopy: Application to the measurement of blood oxygenation and haemoglobin concentration, Phys. Med. Bio. 52(1), 141-168 (2007).
18. A. Q. Bauer et al., Quantitative photoacoustic imaging: Correcting for heterogeneous light fluence distributions using diffuse optical tomography, J. Biomed. Opt. 16(9), 096016 (2011).
19. Z. Guo, S. Hu, and L. V.Wang, Calibration-free absolute quantification of optical absorption coefficients using acoustic spectra in 3D photoacoustic microscopy of biological tissue, Opt. Lett. 35(12), 2067-2069 (2010).
20. Z. Guo et al., Quantitative photoacoustic microscopy of optical absorption coefficients from acoustic spectra in the optical diffusive regime, J. Biomed. Opt. 17(6), 066011 (2012).