Frontal cortical synaptic communication is abnormal in Disc1 genetic mouse models of schizophrenia

Schizophrenia Research

Volumn 146, Issue 1-3, 2013, Pages 264-272

  Holley, Sandra M ^a   Wang, Elizabeth A ^a   Cepeda, Carlos ^a   Jentsch, J David ^b   Ross, Christopher A ^c   Pletnikov, Mikhail V ^c   Levine, Michael S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Disc1; Electrophysiology; EPSCs; Genetic mouse models; Glutamate; Patch clamp; Schizophrenia; Synaptic activity

Indexed keywords

DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; DISC1 GENE; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; FOREBRAIN; FRONTAL CORTEX; GABAERGIC TRANSMISSION; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MOUSE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SCHIZOPHRENIA; SEX DIFFERENCE; SYNAPTIC TRANSMISSION;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DISEASE MODELS, ANIMAL; FEMALE; FRONTAL LOBE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; SCHIZOPHRENIA; SEQUENCE DELETION; SEX CHARACTERISTICS; SYNAPTIC POTENTIALS; SYNAPTIC TRANSMISSION;

EID: 84875943705     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2013.02.007     Document Type: Article

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