Increasing mortality gap for patients diagnosed with schizophrenia over the last three decades - A Danish nationwide study from 1980 to 2010

Schizophrenia Research

Volumn 146, Issue 1-3, 2013, Pages 22-27

  Nielsen, René Ernst ^a,b   Uggerby, Anne Sofie ^a   Jensen, Signe Olrik Wallenstein ^a   McGrath, John Joseph ^c,d  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b Aalborg Psykiatriske Sygehus   (Denmark)

^c QUEENSLAND CENTRE FOR MENTAL HEALTH RESEARCH   (Australia)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Death; Epidemiology; Mental illness; Nationwide; Schizophrenia

Indexed keywords

ADULT; AGE; ARTICLE; AUTOMUTILATION; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; CONTROLLED STUDY; DENMARK; DIABETES MELLITUS; DISEASE REGISTRY; EPILEPSY; FEMALE; HUMAN; INFECTION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEOPLASM; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; RESPIRATORY TRACT DISEASE; SCHIZOPHRENIA; SEX DIFFERENCE; SURVIVAL;

AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; CHI-SQUARE DISTRIBUTION; DENMARK; FEMALE; HEALTH SURVEYS; HUMANS; INCIDENCE; KAPLAN-MEIER ESTIMATE; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; REGISTRIES; RETROSPECTIVE STUDIES; RISK FACTORS; SCHIZOPHRENIA; SEX DISTRIBUTION; SURVIVAL ANALYSIS;

EID: 84875932850     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2013.02.025     Document Type: Article

References (32)

1. Beary M., Hodgson R., Wildgust H.J. A critical review of major mortality risk factors for all-cause mortality in first-episode schizophrenia: clinical and research implications. J. Psychopharmacol. 2012, 26(5 Suppl.):52-61.
2. Capasso R.M., Lineberry T.W., Bostwick J.M., Decker P.A., St Sauver J. Mortality in schizophrenia and schizoaffective disorder: an Olmsted County, Minnesota cohort: 19502005. Schizophr. Res. 2008, 98:287-294.
3. De Hert M., Dekker J.M., Wood D., Kahl K.G., Holt R.I., Moller H.J. Cardiovascular disease and diabetes in people with severe mental illness position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC). Eur. Psychiatry 2009, 24:412-424.
4. Fors B.M., Isacson D., Bingefors K., Widerlov B. Mortality among persons with schizophrenia in Sweden: an epidemiological study. Nord. J. Psychiatry 2007, 61:252-259.
5. Helweg-Larsen K. The Danish register of causes of death. Scand. J. Public Health 2011, 39(7 Suppl.):26-29.
6. Hjortso S., Butler B., Clemmesen L., Jepsen P.W., Kastrup M., Vilmar T., Bech P. The use of case vignettes in studies of interrater reliability of psychiatric target syndromes and diagnoses. A comparison of ICD-8, ICD-10 and DSM-III. Acta Psychiatr. Scand. 1989, 80:632-638.
7. Hoang U., Stewart R., Goldacre M.J. Mortality after hospital discharge for people with schizophrenia or bipolar disorder: retrospective study of linked English hospital episode statistics, 1999-2006. BMJ 2011, 343:d5422.
8. Hor K., Taylor M. Suicide and schizophrenia: a systematic review of rates and risk factors. J. Psychopharmacol. 2010, 24(4 Suppl.):81-90.
9. Hosmer D., Lemeshow S., May S. Applied Survival Analysis: Regression Modelling of Time-to-event Data 2008, John Wiley & Sons, New Jersey. 2nd ed.
10. Hoye A., Jacobsen B.K., Hansen V. Increasing mortality in schizophrenia: are women at particular risk? A follow-up of 1111 patients admitted during 1980-2006 in Northern Norway. Schizophr. Res. 2011, 132:228-232.
11. Lahti M., Tiihonen J., Wildgust H., Beary M., Hodgson R., Kajantie E., Osmond C., Räikkönen K., Eriksson J. Cardiovascular morbidity, mortality and pharmacotherapy in patients with schizophrenia. Psychol. Med. 2012, 1-11.
12. Lambert T.J., Newcomer J.W. Are the cardiometabolic complications of schizophrenia still neglected? Barriers to care. Med. J. Aust. 2009, 190(4 Suppl.):S39-S42.
13. Laursen T.M. Life expectancy among persons with schizophrenia or bipolar affective disorder. Schizophr. Res. 2011, 131:101-104.
14. Laursen T.M., Nordentoft M. Heart disease treatment and mortality in schizophrenia and bipolar disorder - changes in the Danish population between 1994 and 2006. J. Psychiatr. Res. 2011, 45:29-35.
15. Leon D.A. Trends in European life expectancy: a salutary view. Int. J. Epidemiol. 2011, 40:271-277.
16. Mai Q., Holman C.D., Sanfilippo F.M., Emery J.D., Preen D.B. Mental illness related disparities in diabetes prevalence, quality of care and outcomes: a population-based longitudinal study. BMC Med. 2011, 9:118.
17. Mitchell A.J., Lawrence D. Revascularisation and mortality rates following acute coronary syndromes in people with severe mental illness: comparative meta-analysis. Br. J. Psychiatry 2011, 198:434-441.
18. Mitchell A.J., Lord O. Do deficits in cardiac care influence high mortality rates in schizophrenia? A systematic review and pooled analysis. J. Psychopharmacol. 2010, 24(4 Suppl.):69-80.
19. Morden N.E., Lai Z., Goodrich D.E., Mackenzie T., McCarthy J.F., Austin K., Welsh D.E., Bartels S., Kilbourne A.M. Eight-year trends of cardiometabolic morbidity and mortality in patients with schizophrenia. Gen. Hosp. Psychiatry 2012, 34:368-379.
20. Mors O., Perto G.P., Mortensen P.B. The Danish psychiatric central research register. Scand. J. Public Health 2011, 39(7 Suppl.):54-57.
21. Munk-Jorgensen P., Mortensen P.B. Is schizophrenia really on the decrease?. Eur. Arch. Psychiatry Clin. Neurosci. 1993, 242:244-247.
22. Newcomer J.W. Antipsychotic medications: metabolic and cardiovascular risk. J. Clin. Psychiatry 2007, 68(4 Suppl.):8-13.
23. Oud M.J., Schuling J., Groenier K.H., Verhaak P.F., Slooff C.J., Dekker J.H., Meyboom-de Jong B. Care provided by general practitioners to patients with psychotic disorders: a cohort study. BMC Fam. Pract. 2010, 11:92.
24. Rantanen H., Koivisto A.M., Salokangas R.K., Helminen M., Oja H., Pirkola S., Wahlbeck K., Joukamaa M. Five-year mortality of Finnish schizophrenia patients in the era of deinstitutionalization. Soc. Psychiatry Psychiatr. Epidemiol. 2009, 44:135-142.
25. Ratliff J.C., Palmese L.B., Reutenauer E.L., Srihari V.H., Tek C. Obese Schizophrenia spectrum patients have significantly higher 10-year general cardiovascular risk and vascular ages than obese individuals without severe mental illness. Psychosomatics 2013, 54:67-73.
26. Roberts L., Roalfe A., Wilson S., Lester H. Physical health care of patients with schizophrenia in primary care: a comparative study. Fam. Pract. 2007, 24:34-40.
27. Saha S., Chant D., McGrath J. A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time?. Arch. Gen. Psychiatry 2007, 64:1123-1131.
28. Salokangas R.K., Honkonen T., Stengard E., Koivisto A.M. Mortality in chronic schizophrenia during decreasing number of psychiatric beds in Finland. Schizophr. Res. 2002, 54:265-275.
29. Salokangas R.K., Helminen M., Koivisto A.M., Rantanen H., Oja H., Pirkola S., Wahlbeck K., Joukamaa M. Incidence of hospitalised schizophrenia in Finland since 1980: decreasing and increasing again. Soc. Psychiatry Psychiatr. Epidemiol. 2011, 46:343-350.
30. Tiihonen J., Lonnqvist J., WahlbecK K., Klaukka T., Niskanen L., Tanskanen A., Haukka J. 11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study). Lancet 2009, 374:620-627.
31. Tiihonen J., Suokas J.T., Suvisaari J.M., Haukka J., Korhonen P. Polypharmacy with antipsychotics, antidepressants, or benzodiazepines and mortality in schizophrenia. Arch. Gen. Psychiatry 2012, 69:476-483.
32. World Health Organization ICD-10 Classifications of Mental and Behavioural Disorder: Clinical Descriptions and Diagnostic Guidelines 1992, World Health Organization, Geneva.