Correlation of expression and activity of matrix metalloproteinase-9 and -2 in human gingival cells of periodontitis patients

Journal of Periodontal and Implant Science

Volumn 43, Issue 1, 2013, Pages 24-29

  Kim, Kyung A ^a   Chung, Soo Bong ^a   Hawng, Eun Young ^a   Noh, Seung Hyun ^a   Song, Kwon Ho ^b   Kim, Hanna Hyun ^c   Kim, Cheorl Ho ^b   Park, Young Guk ^a  

^a Kyung Hee University   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

Matrix metalloproteinase 2; Matrix metalloproteinase 9; Periodontitis

Indexed keywords

EID: 84875910550     PISSN: 20932278     EISSN: 20932286     Source Type: Journal    
DOI: 10.5051/jpis.2013.43.1.24     Document Type: Article

References (27)

1. Van Dyke TE, Serhan CN. Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases. J Dent Res 2003;82:82-90.
2. DeCarlo AA Jr, Windsor LJ, Bodden MK, Harber GJ, Birkedal-Hansen B, Birkedal-Hansen H. Activation and novel processing of matrix metalloproteinases by a thiol-proteinase from the oral anaerobe Porphyromonas gingivalis. J Dent Res 1997;76:1260-70.
3. Pozo P, Valenzuela MA, Melej C, Zaldivar M, Puente J, Marti nez B, et al. Longitudinal analysis of metalloproteinases, tissue inhibitors of metalloproteinases and clinical parameters in gingival crevicular fluid from periodontitis-affected patients. J Periodontal Res 2005;40:199-207.
4. Vernal R, Dezerega A, Dutzan N, Chaparro A, Leon R, Chandia S, et al. RANKL in human periapical granuloma: possible involvement in periapical bone destruction. Oral Dis 2006;12:283-9.
5. Sorsa T, Tjaderhane L, Konttinen YT, Lauhio A, Salo T, Lee HM, et al. Matrix metalloproteinases: contribution to pathogenesis, diagnosis and treatment of periodontal inflammation. Ann Med 2006;38:306-21.
6. Birkedal-Hansen H. Role of cytokines and inflammatory mediators in tissue destruction. J Periodontal Res 1993;28(6 Pt 2):500-10.
7. Cazalis J, Tanabe S, Gagnon G, Sorsa T, Grenier D. Tetracyclines and chemically modified tetracycline-3 (CMT-3) modulate cytokine secretion by lipopolysaccharide-stimulated whole blood. Inflammation 2009;32:130-7.
8. Uitto VJ, Overall CM, McCulloch C. Proteolytic host cell enzymes in gingival crevice fluid. Periodontol 2000 2003;31:77-104.
9. Sorsa T, Tervahartiala T, Leppilahti J, Hernandez M, Gamonal J, Tuomainen AM, et al. Collagenase-2 (MMP-8) as a point-of-care biomarker in periodontitis and cardiovascular diseases. Therapeutic response to non-antimicrobial properties of tetracyclines. Pharmacol Res 2011;63:108-13.
10. Cox SW, Eley BM, Kiili M, Asikainen A, Tervahartiala T, Sorsa T. Collagen degradation by interleukin-1beta-stimulated gingival fibroblasts is accompanied by release and activation of multiple matrix metalloproteinases and cysteine proteinases. Oral Dis 2006;12:34-40.
11. Reynolds JJ, Meikle MC. Mechanisms of connective tissue matrix destruction in periodontitis. Periodontol 2000 1997;14:144-57.
12. Ryan ME, Golub LM. Modulation of matrix metalloproteinase activities in periodontitis as a treatment strategy. Periodontol 2000 2000;24:226-38.
13. Sorsa T, Tjaderhane L, Salo T. Matrix metalloproteinases (MMPs) in oral diseases. Oral Dis 2004;10:311-8.
14. Ingman T, Sorsa T, Michaelis J, Konttinen YT. Matrix metalloproteinases-1, -3, and -8 in adult periodontitis in situ. An immunohistochemical study. Ann N Y Acad Sci 1994;732:459-61.
15. Corotti MV, Zambuzzi WF, Paiva KB, Menezes R, Pinto LC, Lara VS, et al. Immunolocalization of matrix metalloproteinases-2 and -9 during apical periodontitis development. Arch Oral Biol 2009;54:764-71.
16. Tsagareli ZG, Shishniashvili TE, Gogiashvili LE, Kvachadze TI, Khimshiashvili NB. The level of matrix metalloproteinases and type IV collagen in the gingival mucosa under different clinical forms of periodontitis in pre-and pubertal periods and their prognostic value. Georgian Med News 2012;(206):25-9.
17. Rai B, Kharb S, Jain R, Anand SC. Biomarkers of periodontitis in oral fluids. J Oral Sci 2008;50:53-6.
18. Nishikawa M, Yamaguchi Y, Yoshitake K, Saeki Y. Effects of TNFalpha and prostaglandin E2 on the expression of MMPs in human periodontal ligament fibroblasts. J Periodontal Res 2002;37:167-76.
19. Reynolds JJ, Hembry RM, Meikle MC. Connective tissue degradation in health and periodontal disease and the roles of matrix metalloproteinases and their natural inhibitors. Adv Dent Res 1994;8:312-9.
20. Emingil G, Kuula H, Sorsa T, Atilla G. Gingival crevicular fluid matrix metalloproteinase-25 and -26 levels in periodontal disease. J Periodontol 2006;77:664-71.
21. Tervahartiala T, Pirila E, Ceponis A, Maisi P, Salo T, Tuter G, et al. The in vivo expression of the collagenolytic matrix metalloproteinases (MMP-2, -8, -13, and -14) and matrilysin (MMP-7) in adult and localized juvenile periodontitis. J Dent Res 2000;79:1969-77.
22. Aiba T, Akeno N, Kawane T, Okamoto H, Horiuchi N. Matrix metalloproteinases-1 and -8 and TIMP-1 mRNA levels in normal and diseased human gingivae. Eur J Oral Sci 1996;104:562-9.
23. Shapiro SD, Senior RM. Matrix metalloproteinases. Matrix degradation and more. Am J Respir Cell Mol Biol 1999;20:1100-2.
24. Márton IJ, Kiss C. Protective and destructive immune reactions in apical periodontitis. Oral Microbiol Immunol 2000;15:139-50.
25. Kesanakurti D, Chetty C, Bhoopathi P, Lakka SS, Gorantla B, Tsung AJ, et al. Suppression of MMP-2 attenuates TNF-α induced NF-κB activation and leads to JNK mediated cell death in glioma. PLoS One 2011;6:e19341.
26. Maeso G, Bravo M, Bascones A. Levels of metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-1 in gingival crevicular fluid of patients with periodontitis, gingivitis, and healthy gingiva. Quintessence Int 2007;38:247-52.
27. Murphy G, Docherty AJ, Hembry RM, Reynolds JJ. Metalloproteinases and tissue damage. Br J Rheumatol 1991;30 Suppl 1:25-31.