The onset of antineutrophil cytoplasmic antibody-associated vasculitis immediately after methimazole was switched to propylthiouracil in a woman with graves' disease who wished to become pregnant

Endocrine Journal

Volumn 60, Issue 3, 2013, Pages 383-388

  Kimura, Moritsugu ^a   Seki, Toshiro ^a   Ozawa, Hideki ^a   Ishihara, Toru ^a   Komatsu, Masamichi ^a   Tajiri, Sakurako ^a   Yanagi, Hidetaka ^a   Nishina, Makoto ^a   Noh, Jaeduk Yoshimura ^b   Fukagawa, Masafumi ^a   Takagi, Atsushi ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ITO HOSPITAL   (Japan)

Author keywords

Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis; Graves' disease; Methimazole; Pregnancy; Propylthiouracil

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; CEFTRIAXONE; CIPROFLOXACIN; CREATININE; IODINE; LIOTHYRONINE; PREDNISONE; PROPYLTHIOURACIL; THIAMAZOLE; THYROTROPIN;

ADULT; ALBUMIN BLOOD LEVEL; ANCA ASSOCIATED VASCULITIS; ANTIBODY TITER; BACTERIAL INFECTION; CASE REPORT; CLINICAL FEATURE; CLINICAL OBSERVATION; COUGHING; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG DOSE REDUCTION; DRUG FEVER; DRUG SAFETY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; DYSPNEA; ELECTROCARDIOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLU LIKE SYNDROME; GRAVES DISEASE; HEADACHE; HEMATURIA; HEMOPTYSIS; HUMAN; HYPOXEMIA; IMMUNOSUPPRESSIVE TREATMENT; LIOTHYRONINE BLOOD LEVEL; LUNG INFILTRATE; MYELOPEROXIDASE ANCA ASSOCIATED VASCULITIS; NOTE; PATIENT MONITORING; PHYSICAL EXAMINATION; PROTEINURIA; SINUS TACHYCARDIA; SMOKING HABIT; THORAX RADIOGRAPHY; THYROTROPIN BLOOD LEVEL; URINALYSIS;

ABNORMALITIES, DRUG-INDUCED; ADULT; ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY-ASSOCIATED VASCULITIS; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; ANTITHYROID AGENTS; FEMALE; GRAVES DISEASE; HUMANS; METHIMAZOLE; PEROXIDASE; PREGNANCY; PREGNANCY COMPLICATIONS; PROPYLTHIOURACIL;

EID: 84875909766     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ12-0212     Document Type: Note

References (20)

1. Davis LE, Lucas MJ, Hankins GD, Roark ML, Cunningham FG (1989) Thyrotoxicosis complicating pregnancy. Am J Obstet Gynecol 160: 63-70.
2. Momotani N, Ito K (1991) Treatment of pregnant patients with Basedow's disease. Exp Clin Endocrinol 97: 268-274.
3. Cooper DS (2005) Antithyroid drugs. N Engl J Med 352: 905-917.
4. Nakamura H, Noh JY, Itoh K, Fukata S, Miyauchi A, et al. (2007) Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease. J Clin Endocrinol Metab 92: 2157- 2162.
5. The Japan Thyroid Association (2011) The patients of special Graves' disease. In: Guideline for the treatment of Graves' disease in Japan. Nankodo, Tokyo: 123-134 (In Japanese).
6. Yoshihara A, Noh JY, Yamaguchi T, Ohye H, Sato S, et al. (2012) Treatment of Graves' disease with antithyroid drugs in the first trimester of pregnancy and the prevalence of congenital malformation. J Clin Endocrinol Metab 97: 2396-2403.
7. Morita S, Ueda Y, Eguchi K (2000) Anti-thyroid druginduced ANCA-associated vasculitis: a case report and review of the literature. Endocr J 47: 467-470.
8. Ahmed K, Rao S, Simha V (2010) Antineutrophil cytoplasmic antibody-positive vasculitis in a patient with graves disease: cross-reaction between propylthiouracil and methimazole. Endocr Pract 16: 449-451.
9. Chen YX, Yu HJ, Ni LY, Zhang W, Xu YW, et al. (2007) Propylthiouracil-associated antineutrophil cytoplasmic autoantibody-positive vasculitis: retrospective study of 19 cases. J Rheumatol 34: 2451-2456.
10. Gao Y, Chen M, Ye H, Yu F, Guo XH, et al. (2008) Long-term outcomes of patients with propylthiouracil- induced anti-neutrophil cytoplasmic autoantibodyassociated vasculitis. Rheumatology (Oxford) 47: 1515-1520.
11. Noh JY, Yasuda S, Sato S, Matsumoto M, Kunii Y, et al. (2009) Clinical characteristics of myeloperoxidase antineutrophil cytoplasmic antibody-associated vasculitis caused by antithyroid drugs. J Clin Endocrinol Metab 94: 2806-2811.
12. Gunton JE, Stiel J, Clifton-Bligh P, Wilmshurst E, McElduff A (2000) Prevalence of positive anti-neutrophil cytoplasmic antibody (ANCA) in patients receiving anti-thyroid medication. Eur J Endocrinol 142: 587- 590.
13. Tanemoto M, Miyakawa H, Hanai J, Yago M, Kitaoka M, et al. (1995) Myeloperoxidase-antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis complicating the course of Graves' disease: report of three adult cases. Am J Kidney Dis 26: 774-780.
14. Sera N, Ashizawa K, Ando T, Abe Y, Ide A, et al. (2000) Treatment with propylthiouracil is associated with appearance of antineutrophil cytoplasmic antibodies in some patients with Graves' disease. Thyroid 10: 595-599.
15. Volpe R (1989) Graves' disease. In: Burrow GN, Oppenheimer JH, Volpe R (eds) Thyroid function and disease. WB Saunders, Philadelphia: 214.
16. Cooper DS, Rivkees SA (2009) Putting propylthiouracil in perspective. J Clin Endocrinol Metab 94: 1881-1882.
17. Noh JY, Asari T, Hamada N, Makino F, Ishikawa N, et al. (2001) Frequency of appearance of myeloperoxidaseantineutrophil cytoplasmic antibody (MPO-ANCA) in Graves' disease patients treated with propylthiouracil and the relationship between MPO-ANCA and clinical manifestations. Clin Endocrinol (Oxf) 54: 651-654.
18. Ohtsuka M, Yamasita Y, Doi M, Hasegawa S (1997) Propylthiouracil-induced alveolar hemorrhage associated with antineutrophil cytoplasmic antibody. Eur Respir J 10: 1405-1407.
19. Irani F, Elkambergy H, Naraharisetty K, Jamal R (2009) Propylthiouracil-induced leucocytoclastic vasculitis with pulmonary hemorrhage treated with plasmapheresis. Am J Med Sci 337: 470-472.
20. Dhillon SS, Singh D, Doe N, Qadri AM, Ricciardi S, et al. (1999) Diffuse alveolar hemorrhage and pulmonary capillaritis due to propylthiouracil. Chest 116: 1485-1488.