Recruitment, retention, and blinding in clinical trials

American Journal of Occupational Therapy

Volumn 67, Issue 2, 2013, Pages 154-161

  Page, Stephen J ^a   Persch, Andrew C ^a,b  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b School of Health and Rehabilitation Sciences   (United States)

Author keywords

Behavioral research; Clinical trials as topic; Double blind method; Patient dropouts; Patient selection

Indexed keywords

CLINICAL TRIAL (TOPIC); CONFERENCE PAPER; DOUBLE BLIND PROCEDURE; HOSPITAL MANAGEMENT; HUMAN; OCCUPATIONAL THERAPY; PATIENT COMPLIANCE; PATIENT SELECTION; REMINDER SYSTEM; SINGLE BLIND PROCEDURE; STANDARD;

APPOINTMENTS AND SCHEDULES; CLINICAL TRIALS AS TOPIC; DOUBLE-BLIND METHOD; HUMANS; OCCUPATIONAL THERAPY; PATIENT COMPLIANCE; PATIENT SELECTION; REMINDER SYSTEMS; SINGLE-BLIND METHOD;

EID: 84875846817     PISSN: 02729490     EISSN: None     Source Type: Journal    
DOI: 10.5014/ajot.2013.006197     Document Type: Conference Paper

References (24)

1. American Occupational Therapy Association. (2007). AOTA's Centennial Vision and executive summary. American Journal of Occupational Therapy, 61, 613-614. http://dx.doi.org/10.5014/ajot.61.6.613
2. Bedlack, R. S., & Cudkowicz, M. E. (2009). Clinical trials in progressive neurological diseases: Recruitment, enrollment, retention and compliance. Frontiers of Neurology and Neuroscience, 25, 144-151. http://dx.doi.org/10.1159/000209493
3. Britton, A., Murray, D., Bulstrode, C., McPherson, K., & Denham, R. (1995). Loss to follow-up: Does it matter? Lancet, 345, 1511-1512. http://dx.doi.org/10.1016/S0140-6736(95)91071-9
4. Cooley, M. E., Sarna, L., Brown, J. K., Williams, R. D., Chernecky, C., Padilla, G., & Danao, L. L. (2003). Challenges of recruitment and retention in multisite clinical research. Cancer Nursing, 26, 376-384, quiz 385-386. http://dx.doi.org/10.1097/00002820-200310000-00006
5. Corrigan, P. W., & Salzer, M. S. (2003). The conflict between random assignment and treatment preference: Implications for internal validity. Evaluation and Program Planning, 26, 109-121. http://dx.doi.org/10.1016/S0149- 7189(03)00014-4 (Pubitemid 36509149)
6. Driscoll, K. A., Killian, M., Johnson, S. B., Silverstein, J. H., & Deeb, L. C. (2009). Predictors of study completion and withdrawal in a randomized clinical trial of a pediatric diabetes adherence intervention. Contemporary Clinical Trials, 30, 212-220. http://dx.doi.org/10.1016/j.cct.2009. 01.008
7. Friedberg, J. P., Lipsitz, S. R., & Natarajan, S. (2010). Challenges and recommendations for blinding in behavioral interventions illustrated using a case study of a behavioral intervention to lower blood pressure. Patient Education and Counseling, 78, 5-11. http://dx.doi.org/10.1016/j.pec. 2009.04.009
8. Friedman, L. M., Furberg, C., & DeMets, D. L. (1998). Fundamentals of clinical trials. New York: Springer.
9. Green, L. A., Gorenflo, D. W., & Wyszewianski, L.; Michigan Consortium for Family Practice Research. (2002). Validating an instrument for selecting interventions to change physician practice patterns: A Michigan Consortium for Family Practice Research study. Journal of Family Practice, 51, 938-942. (Pubitemid 35291615)
10. Iber, F. L., Riley, W. A., & Murray, P. J. (1987). Conducting clinical trials. New York: Plenum Medical.
11. Johnson, M. O., & Remien, R. H. (2003). Adherence to research protocols in a clinical context: Challenges and recommendations from behavioral intervention trials. American Journal of Psychotherapy, 57, 348-360. (Pubitemid 41270147)
12. Loscalzo, J. (2009). Pilot trials in clinical research: Of what value are they? Circulation, 119, 1694-1696.
13. Lowe, C. J., Wilson, M. S., Sackley, C. M., & Barker, K. L. (2011). Blind outcome assessment: The development and use of procedures to maintain and describe blinding in a pragmatic physiotherapy rehabilitation trial. Clinical Rehabilitation, 25, 264-274. http://dx.doi.org/10.1177/0269215510380824
14. Marcellus, L. (2004). Are we missing anything? Pursuing research on attrition. Canadian Journal of Nursing Research, 36, 82-98. (Pubitemid 39406968)
15. Meinert, C. L., & Tonascia, S. (1986). Clinical trials: Design, conduct, and analysis. New York: Oxford University Press.
16. Moher, D., Hopewell, S., Schulz, K. F., Montori, V., Gøtzsche, P. C., Devereux, P. J., ⋯ Altman, D. G. (2010). CONSORT 2010 explanation and elaboration: Updated guidelines for reporting parallel group randomised trials. BMJ, 340, c869. http://dx.doi.org/10.1136/bmj.c869
17. Orrell-Valente, J. K., Pinderhughes, E. E., Valente, E., Jr., & Laird, R. D. (1999). If it's offered, will they come? Influences on parents' participation in a community-based conduct problems prevention program. American Journal of Community Psychology, 27, 753-783. http://dx.doi.org/10.1023/A: 1022258525075
18. Penson, D. F., & Wei, J. (2006). Clinical research methods for surgeons. Totowa, NJ: Humana Press.
19. Persch, A. C., & Page, S. J. (2013). Protocol development, treatment fidelity, adherence to treatment, and quality control. American Journal of Occupational Therapy, 67, 146-153.
20. Pocock, S. J. (1983). Clinical trials: A practical approach. Chichester, England: Wiley.
21. Polit, D. F. (2011). Blinding during the analysis of research data. International Journal of Nursing Studies, 48, 636-641. http://dx.doi.org/10. 1016/j.ijnurstu.2011.02.010
22. Portney, L. G., & Watkins, M. P. (2000). Foundations of clinical research: Applications to practice. Upper Saddle River, NJ: Prentice Hall.
23. Sackett, D. L., Rosenberg, W. M. C., Gray, J. A. M., Haynes, R. B., & Richardson, W. S. (1996). Evidence based medicine: What it is and what it isn't. BMJ, 312, 71-72. http://dx.doi.org/10.1136/bmj.312.7023.71
24. Schulz, K. F., Altman, D. G., & Moher, D.; CONSORT Group. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. BMC Medicine, 8, 18-26. http://dx.doi.org/10.1186/1741-7015- 8-18