The aggressive phenotype revisited: Utilization of higher-risk liver allografts

American Journal of Transplantation

Volumn 13, Issue 4, 2013, Pages 936-942

  Garonzik Wang, J M ^a   James, N T ^a   Arendonk, K J Van ^a   Gupta, N ^a   Orandi, B J ^a   Hall, E C ^a,b   Massie, A B ^a   Montgomery, R A ^a   Dagher, N N ^a   Singer, A L ^a   Cameron, A M ^a   Segev, D L ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Extended criteria donors; graft acceptance; liver transplantation; transplant centers

Indexed keywords

ADULT; ALLOGRAFT; ARTICLE; DISEASE SEVERITY; GRAFT RECIPIENT; HEALTH CARE UTILIZATION; HUMAN; LIVER ALLOGRAFT; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL;

ADULT; AGED; CLUSTER ANALYSIS; END STAGE LIVER DISEASE; GRAFT SURVIVAL; HUMANS; LIVER FUNCTION TESTS; LIVER TRANSPLANTATION; MIDDLE AGED; PHENOTYPE; REGRESSION ANALYSIS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTS;

EID: 84875838857     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12151     Document Type: Article

References (33)

1. Brown RS, Rush SH, Rosen HR, et al. Liver and intestine transplantation. Am J Transplant 2004; 4 (Suppl 9): 81-92. (Pubitemid 38858997)
2. Organ Procurement and Transplantation Network: Liver Transplantation Waiting LIst. January 1, 2000-December 31, 2010. Available at: http://optn.transplant.hrsa.gov/latestData/rptData.asp. Accessed November 11, 2011.
3. Hoofnagle JH, Carithers RL, Jr., Shapiro C, Ascher N., Fulminant hepatic failure: Summary of a workshop. Hepatology 1995; 21: 240-252.
4. Markmann JF, Markmann JW, Markmann DA, et al. Preoperative factors associated with outcome and their impact on resource use in 1148 consecutive primary liver transplants. Transplantation 2001; 72: 1113-1122. (Pubitemid 32924087)
5. Alexander JW, Vaughn WK,. The use of "marginal" donors for organ transplantation. The influence of donor age on outcome. Transplantation 1991; 51: 135-141.
6. Tisone G, Manzia TM, Zazza S, et al. Marginal donors in liver transplantation. Transplant Proc 2004; 36: 525-526. (Pubitemid 38541524)
7. Tector AJ, Mangus RS, Chestovich P, et al. Use of extended criteria livers decreases wait time for liver transplantation without adversely impacting posttransplant survival. Ann Surg 2006; 244: 439-450.
8. Gruttadauria S, Cintorino D, Mandala L, et al. Acceptance of marginal liver donors increases the volume of liver transplant: Early results of a single-center experience. Transplant Proc 2005; 37: 2567-2568. (Pubitemid 41354671)
9. Renz JF, Kin C, Kinkhabwala M, et al. Utilization of extended donor criteria liver allografts maximizes donor use and patient access to liver transplantation. Ann Surg 2005; 242: 556-563; discussion 563-555.
10. Rinella ME, Alonso E, Rao S, et al. Body mass index as a predictor of hepatic steatosis in living liver donors. Liver Transpl 2001; 7: 409-414. (Pubitemid 32492578)
11. Hoofnagle JH, Lombardero M, Zetterman RK, et al. Donor age and outcome of liver transplantation. Hepatology 1996; 24: 89-96. (Pubitemid 26249418)
12. Alkofer B, Samstein B, Guarrera JV, et al. Extended-donor criteria liver allografts. Semin Liver Dis 2006; 26: 221-233. (Pubitemid 44141929)
13. Feng S, Goodrich NP, Bragg-Gresham JL, et al. Characteristics associated with liver graft failure: The concept of a donor risk index. Am J Transplant 2006; 6: 783-790. (Pubitemid 43345017)
14. Busuttil RW, Tanaka K., The utility of marginal donors in liver transplantation. Liver Transpl 2003; 9: 651-663. (Pubitemid 36874450)
15. Gastaca M, Valdivieso A, Pijoan J, et al. Donors older than 70 years in liver transplantation. Transplant Proc 2005; 37: 3851-3854. (Pubitemid 43015188)
16. Scotte M, Dousset B, Calmus Y, Conti F, Houssin D, Chapuis Y., The influence of cold ischemia time on biliary complications following liver transplantation. J Hepatol 1994; 21: 340-346. (Pubitemid 24308756)
17. Cassuto JR, Patel SA, Tsoulfas G, Orloff MS, Abt PL,. The cumulative effects of cold ischemic time and older donor age on liver graft survival. J Surg Res 2008; 148: 38-44.
18. Yu L, Koepsell T, Manhart L, Ioannou G,. Survival after orthotopic liver transplantation: The impact of antibody against hepatitis B core antigen in the donor. Liver Transpl 2009; 15: 1343-1350.
19. Reich DJ, Hong JC,. Current status of donation after cardiac death liver transplantation. Curr Opin Organ Transplant 2010; 15: 316-321.
20. Mangus RS, Fridell JA, Vianna RM, et al. No difference in clinical transplant outcomes for local and imported liver allografts. Liver Transpl 2009; 15: 640-647.
21. Schemmer P, Nickkholgh A, Hinz U, et al. Extended donor criteria have no negative impact on early outcome after liver transplantation: A single-center multivariate analysis. Transplant Proc 2007; 39: 529-534. (Pubitemid 46386206)
22. Nickkholgh A, Weitz J, Encke J, et al. Utilization of extended donor criteria in liver transplantation: A comprehensive review of the literature. Nephrol Dial Transplant 2007; 22 (Suppl 8): viii29-viii36.
23. Garonzik-Wang JM, James NT, Weatherspoon KC, et al. The aggressive phenotype: Center-level patterns in the utilization of suboptimal kidneys. Am J Transplant 2012; 12: 400-408.
24. Grams ME, Womer KL, Ugarte RM, Desai NM, Montgomery RA, Segev DL,. Listing for expanded criteria donor kidneys in older adults and those with predicted benefit. Am J Transplant 2010; 10: 802-809.
25. Bambha K, Kim WR, Kremers WK, et al. Predicting survival among patients listed for liver transplantation: An assessment of serial MELD measurements. Am J Transplant 2004; 4: 1798-1804. (Pubitemid 39434440)
26. Kremers WK, van IM, Kim WR, et al. MELD score as a predictor of pretransplant and posttransplant survival in OPTN/UNOS status 1 patients. Hepatology 2004; 39: 764-769. (Pubitemid 38337656)
27. Narayanan Menon KV, Nyberg SL, Harmsen WS, et al. MELD and other factors associated with survival after liver transplantation. Am J Transplant 2004; 4: 819-825. (Pubitemid 38637583)
28. Schaffer RL, 3rd, Kulkarni S, Harper A, Millis JM, Cronin DC, 2nd. The sickest first? Disparities with model for end-stage liver disease-based organ allocation: One region's experience. Liver Transpl 2003; 9: 1211-1215. (Pubitemid 37407991)
29. Trotter JF, Osgood MJ,. MELD scores of liver transplant recipients according to size of waiting list: Impact of organ allocation and patient outcomes. JAMA 2004; 291: 1871-1874. (Pubitemid 38509500)
30. Wiesner R, Edwards E, Freeman R, et al. Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology 2003; 124: 91-96. (Pubitemid 36055342)
31. Edwards EB, Roberts JP, McBride MA, Schulak JA, Hunsicker LG,. The effect of the volume of procedures at transplantation centers on mortality after liver transplantation. N Engl J Med 1999; 341: 2049-2053. (Pubitemid 30035953)
32. Segev DL, Kucirka LM, Nguyen GC, et al. Effect modification in liver allografts with prolonged cold ischemic time. Am J Transplant 2008; 8: 658-666. (Pubitemid 351287540)
33. Segev DL, Maley WR, Simpkins CE, et al. Minimizing risk associated with elderly liver donors by matching to preferred recipients. Hepatology 2007; 46: 1907-1918.