A randomised controlled trial of sublingual misoprostol and intramuscular oxytocin for prevention of postpartum haemorrhage

Journal of Obstetrics and Gynaecology

Volumn 33, Issue 3, 2013, Pages 277-279

  Al Sawaf, A ^a   El Mazny, A ^a   Shohayeb, A ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Misoprostol; Oxytocin; Postpartum haemorrhage; Vaginal delivery

Indexed keywords

METHYLERGOMETRINE MALEATE; MISOPROSTOL; OXYTOCIN;

ADD ON THERAPY; ADOLESCENT; ADULT; ARTICLE; BLOOD TRANSFUSION; BLOOD VESSEL CLIP; CHEMOPROPHYLAXIS; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DIASTOLIC BLOOD PRESSURE; DRUG EFFICACY; DRUG SAFETY; DRUG STABILITY; FEMALE; FEVER; GESTATIONAL AGE; HUMAN; LABOR STAGE 3; LOW RISK POPULATION; MAJOR CLINICAL STUDY; NAUSEA AND VOMITING; OBSTETRIC PATIENT; POSTPARTUM HEMORRHAGE; PREGNANCY; PREGNANT WOMAN; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; ROOM TEMPERATURE; SHIVERING; SIDE EFFECT; SYSTOLIC BLOOD PRESSURE; TACHYCARDIA; UMBILICAL CORD; UTERINE ATONY; VAGINAL DELIVERY;

ADMINISTRATION, SUBLINGUAL; ADOLESCENT; ADULT; FEMALE; HUMANS; INJECTIONS, INTRAMUSCULAR; MISOPROSTOL; OXYTOCICS; OXYTOCIN; POSTPARTUM HEMORRHAGE; PREGNANCY; YOUNG ADULT;

EID: 84875830205     PISSN: 01443615     EISSN: 13646893     Source Type: Journal    
DOI: 10.3109/01443615.2012.755503     Document Type: Article

References (16)

1. Bouwmeester FW, Bolte AC, van Geijn HP. 2005. Pharmacological and surgical therapy for primary postpartum hemorrhage. Current Pharmaceutical Design 11: 759-773. (Pubitemid 40347979)
2. Caliskan E, Dilbaz B, Meydanli MM, Ozturk N, Narin MA, Haberal A. 2003. Oral misoprostol for the third stage of labor: a randomized controlled trial. Obstetrics and Gynecology 101: 921-928. (Pubitemid 36561255)
3. Chong YS, Su LL, Arulkumaran S. 2004. Current strategies for the prevention of postpartum hemorrhage in the third stage of labor. Current Opinion in Obstetrics and Gynecology 16: 143-150. (Pubitemid 38519749)
4. Davies GA, Tessier JL, Woodman MC, Lipson A, Hahn PM. 2005. MaterUnal hemodynamics aft er oxytocin bolus compared with infusion in the third stage of labor: a randomized controlled trial. Obstetrics and Gynecology 105: 294-299. (Pubitemid 40229445)
5. El-Refaey H, Nooh R, O'Brien P, Abdalla M, Geary M, Walder J et al. 2000. the misoprostol third stage of labor study: a randomized controlled comparison between orally administered misoprostol and standard management. British Journal of Obstetrics and Gynaecology 107: 1104-1110.
6. Lam H, Tang OS, Lee CP, Ho PC. 2004. A pilot-randomized comparison of sublingual misoprostol with syntometrine on the blood loss in third stage of labor. Acta Obstetricia et Gynecologica Scandinavica 83: 647-650. (Pubitemid 38938753)
7. Miller S, Lester F, Hensleigh P. 2004. Prevention and treatment of postpartum hemorrhage: new advances for low-resource settings. Journal of Midwifery and Women's Health 49: 283-292. (Pubitemid 38967312)
8. Petersson M. 2002. Cardiovascular eff ects of oxytocin. Progress in Brain Research 139: 281-288.
9. Prata N, Sreenivas A, Greig F, Walsh J, Potts M. 2010. Setting priorities for safe motherhood interventions in resource-scarce settings. Health Policy 94: 1-13.
10. Rizvi F, Mackey R, Barrett T, Mckenna P, Geary M. 2004. Successful reduction of massive postpartum haemorrhage by use of guidelines and staff education. British Journal of Obstetrics and Gynaecology 111: 495-498. (Pubitemid 38621883)
11. Sloan NL, Durocher J, Aldrich T, Blum J, Winikoff B. 2010. What measured blood loss tells us about postpartum bleeding: a systematic review. British Journal of Obstetrics and Gynaecology 117: 788-800.
12. Tang OS, Schweer H, Seyberth HW, Sharon HW, Lee SW, Ho PC. 2002. Pharmacokinetics of diff erent routes of administration of misoprostol. Human Reproduction 17: 332-336. (Pubitemid 34168436)
13. Vimala N, Mittal S, Kumar S. 2006. Sublingual misoprostol versus oxytocin infusion to reduce blood loss at cesarean section. InternatioUnal Journal of Gynecology and Obstetrics 92: 106-110. (Pubitemid 43098864)
14. Williams JW, Rudy TA, Yaksh TL, Viswanathan CT. 2003. An extensive exploration of the rat brain for sites mediating PG-induced hyperthermia. Brain Research 120: 251-262.
15. Winikoff B, Dabash R, Durcher J, Darwish E, Nguyen TN, Leon W et al. 2010. Treatment of post-partum haemorrhage with sublingual misoprostol versus oxytocin in women not exposed to oxytocin during labour: a double-blind randomized, non-inferiority trial. Lancet 375: 210-216.
16. Zachariah ES, Naidu M, Seshadri L. 2006. Oral misoprostol in the third stage of labor. InternatioUnal Journal of Gynaecology and Obstetrics 92: 23-26. (Pubitemid 41773712)