Mycobacterium bovis Δmce2 double deletion mutant protects cattle against challenge with virulent M. bovis

Tuberculosis

Volumn 93, Issue 3, 2013, Pages 363-372

  Blanco, Federico Carlos ^a   Bianco, María Verónica ^a   Garbaccio, Sergio ^a   Meikle, Virginia ^a   Gravisaco, María José ^a   Montenegro, Valeria ^a   Alfonseca, Edgar ^b   Singh, Mahavir ^c   Barandiaran, Soledad ^d   Canal, Ana ^e   Vagnoni, Lucas ^a   Buddle, Bryce Malcom ^f   Bigi, Fabiana ^a   Cataldi, Angel ^a  

^a INSTITUTO NACIONAL DE TECNOLOGÍA AGROPECUARIA INTA   (Argentina)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c UNAM ^*  (Germany)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^e UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

^f AGRESEARCH GRASSLANDS   (New Zealand)

Author keywords

Bovine tuberculosis; Live vaccine; mce; Mycobacterium bovis

Indexed keywords

BACTERIAL VACCINE; BCG VACCINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR; MESSENGER RNA; PROTEIN DELTAMCE2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BACTERIAL VIRULENCE; BLOOD SAMPLING; BOVINE TUBERCULOSIS; CATTLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMETRY; GENE DELETION; HISTOPATHOLOGY; INTERFERON GAMMA RELEASE ASSAY; LUNG; MYCOBACTERIUM BOVIS; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION; TUBERCULIN TEST;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL LOAD; BACTERIAL PROTEINS; BCG VACCINE; CATTLE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; GENE DELETION; INTERFERON-GAMMA; INTERFERON-GAMMA RELEASE TESTS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MYCOBACTERIUM BOVIS; TUBERCULIN; TUBERCULIN TEST; TUBERCULOSIS VACCINES; TUBERCULOSIS, BOVINE; VACCINES, ATTENUATED; VIRULENCE;

EID: 84875805711     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2013.02.004     Document Type: Article

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