The cholinergic and non-cholinergic effects of organophosphates and oximes in cultured human myoblasts

Chemico-Biological Interactions

Volumn 203, Issue 1, 2013, Pages 144-148

  Katalinić, Maja ^a   Miš, Katarina ^b   Pirkmajer, Sergej ^b   Grubič, Zoran ^b   Kovarik, Zrinka ^a   Marš, Tomaž ^b  

^a INSTITUTE FOR MEDICAL RESEARCH AND OCCUPATIONAL HEALTH   (Croatia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Acetylcholinesterase; Antidotes; Cytokines; Heat shock proteins; Myopathy; Tabun

Indexed keywords

ACETYLCHOLINESTERASE; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; INTERLEUKIN 6; MESSENGER RNA; ORGANOPHOSPHATE; OXIME; TABUN;

ANTICHOLINERGIC EFFECT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL PROTECTION; CHEMICAL STRUCTURE; CHOLINERGIC ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MUSCLE CELL; MUSCLE REGENERATION; MYOBLAST; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; RNA STABILITY; SATELLITE CELL; WESTERN BLOTTING;

ACETYLCHOLINESTERASE; CELLS, CULTURED; CHOLINESTERASE INHIBITORS; CHOLINESTERASE REACTIVATORS; GPI-LINKED PROTEINS; HSP27 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-6; MYOBLASTS, SKELETAL; ORGANOPHOSPHATES; OXIMES; PYRIDINIUM COMPOUNDS; REGENERATION; RNA STABILITY; RNA, MESSENGER;

EID: 84875805509     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.09.015     Document Type: Conference Paper

References (28)

1. D.A. Jett, and P.J. Lein Noncholinesterase mechanisms of central and peripheral neurotoxicity: muscarinic receptors and other targets R.C. Gupta, Toxicology of Organophosphate and Carbamate Compounds 2006 Elsevier Academic Press Amsterdam 233 245
2. T.V. Damodaran Molecular and transcriptional response to sarin exposure R.C. Gupta, Handbook of Toxicology of Chemical Warfare Agents 2009 Elsevier Academic Press Amsterdam 665 682
3. H.J. Preusser The ultrastructure of the motor end plate in the diaphragm of rats and changes after inhibition of acetylcholinesterase Z. Zellforsch. Mikrosk. Anat. 80 1967 436 457
4. L. Wecker, T. Kiauta, and W.-D. Dettbarn Relationship between acetylcholinesterase inhibition and the development of a myopathy J. Pharmacol. Exp. Ther. 206 1978 97 104
5. W.-D. Dettbarn, D. Milatovic, and R.C. Gupta Oxidative stress in anticholinesterase-induced excitotoxicity R.C. Gupta, Toxicology of Organophosphate and Carbamate Compounds 2006 Elsevier Academic Press Amsterdam 511 530
6. R. Bischoff Tissue culture studies on the origin of myogenic cells during muscle regeneration in the rat A. Mauro, Muscle Regeneration 1979 Raven Press New York 13 30
7. S. Pirkmajer, D. Filipović, T Marš, K. Mis, and Z. Grubic HIF-1alpha response to hypoxia is functionally separated from the glucocorticoid stress response in the in vitro regenerating human skeletal muscle Am. J. Physiol. Regul. Integr. Comp. Physiol. 299 2010 1693 1700
8. K. Kuča, J. Bielavsky, J. Cabal, and J. Kassa Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase Bioorg. Med. Chem. Lett. 13 2003 3545 3547
9. K. Kuča, and J. Kassa A comparison of the ability of a new bispyridinium oxime-1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium) butane dibromide and currently used oximes to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods J. Enzym. Inhib. Med. Chem. 18 2003 529 535
10. M. Čalić, A. Lucić Vrdoljak, B. Radić, D. Jelić, D. Jun, K. Kuča, and Z. Kovarik In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity Toxicology 219 2006 85 96
11. A. Lucić Vrdoljak, M. Čalić, B. Radić, S. Berend, D. Jun, K. Kuča, and Z. Kovarik Pretreatment with pyridinium oximes improves antidotal therapy against tabun poisoning Toxicology 228 2006 41 50
12. F. Worek, H. Thiermann, L. Szinicz, and P. Eyer Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes Biochem. Pharmacol. 68 11 2004 2237 2248
13. O. Prelovsek, T. Mars, M. Jevsek, M. Podbregar, and Z. Grubic High dexamethasone concentration prevents stimulatory effects of TNF-alpha and LPS on IL-6 secretion from the precursors of human muscle regeneration Am. J. Physiol. Regul. Integr. Comp. Physiol. 291 2006 1651 1656
14. S. Pirkmajer, and A.V. Chibalin Serum starvation: caveat emptor Am. J. Physiol. Cell Physiol. 301 2011 272 279
15. K. Pegan, U. Matković, T. Marš, K. Miš, S. Pirkmajer, J. Brecelj, and Z. Grubič Acetylcholinesterase is involved in apoptosis in the precursors of human muscle regeneration Chem. Biol. Interact. 187 2010 96 100
16. A. Golicnik, M. Podbregar, M. Lainscak, S.D. Anker, Z. Grubic, and T. Mars Atorvastatin modulates constitutive and lipopolysaccharide induced IL-6 secretion in precursors of human skeletal muscle Afr. J. Pharm. Pharmacol. 6 2012 241 247
17. G.L. Ellman, K.D. Courtney, V. Andres Jr, and R.M. Featherstone New and rapid colorimetric determination of acetylcholinesterase activity Biochem. Pharmacol. 7 1961 88 95
18. P. Eyer, F. Worek, D. Kiderlen, G. Šinko, A. Štuglin, V. Simeon-Rudolf, and E. Reiner Molar absorption coefficients for the reduced Ellman reagent: reassessment Anal. Biochem. 312 2003 224 227
19. S.B. Chargé, and M.A. Rudnicki Cellular and molecular regulation of muscle regeneration Physiol. Rev. 2004 209 228
20. K. Mis, T. Mars, M. Golicnik, M. Jevsek, and Z. Grubic Effects of acetylcholinesterase gene silencing on its activity in cultured human skeletal muscle J. Mol. Neurosci. 30 2006 31 32
21. T. Mars, K. Mis, S. Pirkmajer, and Z. Grubic The effects of organophosphates in the early stages of human muscle regeneration R.C. Gupta, Handbook of Toxicology of Chemical Warfare Agents 2009 Elsevier Academic Press Amsterdam 665 682
22. M.A. Febbraio, and B.K. Pedersen Contraction-induced myokine production and release: is skeletal muscle an endocrine organ? Exerc. Sport Sci. Rev. 33 2005 114 119
23. M. Cantini, M.L. Massimino, E. Rapizzi, K. Rossini, C. Catani, L. Dalla Libera, and U. Carraro Human satellite cell proliferation in vitro is regulated by autocrine secretion of IL-6 stimulated by a soluble factor(s) released by activated monocytes Biochem. Biophys. Res. Commun. 216 1995 49 53
24. J.T. Silver, and E.G. Noble Regulation of survival gene hsp70 Cell Stress Chaperon. 17 2012 1 9
25. S. Mariggio, A. Bavec, E. Natale, P. Zizza, M. Salmona, D. Corda, and M. Di Girolamo Galpha13 mediates activation of the cytosolic phospholipase A2alpha through fine regulation of ERK phosphorylation Cell Signal 18 2006 2200 2208
26. I. Furlan, and R.O. Godinho Developing skeletal muscle cells express functional muscarinic acetylcholine receptors coupled to different intracellular signalling system Brit. J. Pharmacol. 146 2005 389 396
27. T. Mankame, R. Hokanson, R. Fudge, R. Chowdhary, and D. Busbee Alteration of gene expression in human cells treated with the agricultural chemical diazinon: possible interaction in fetal development Hum. Exp. Toxicol. 25 2006 225 233
28. Z. Grubic, and A. Tomazic Mechanism of action of HI-6 on soman inhibition of acetylcholinesterase in preparations of rat and human skeletal muscle; comparison to SAD-128 and PAM-2 Arch. Toxicol. 63 1989 68 71