Hamster-adapted sin nombre virus causes disseminated infection and efficiently replicates in pulmonary endothelial cells without signs of disease

Journal of Virology

Volumn 87, Issue 8, 2013, Pages 4778-4782

  Safronetz, David ^a   Prescott, Joseph ^a   Haddock, Elaine ^a   Scott, Dana P ^c   Feldmann, Heinz ^a,b   Ebihara, Hideki ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

^c Rocky Mountain Veterinary Branch   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; VIRUS ANTIGEN; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE MODEL; HAMSTER; HANTAVIRUS PULMONARY SYNDROME; HEART; HOST PATHOGEN INTERACTION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; KIDNEY; LIVER; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; TISSUE DISTRIBUTION; VIRAL CLEARANCE; VIRUS CULTURE; VIRUS REPLICATION;

ADAPTATION, BIOLOGICAL; ANIMALS; ASYMPTOMATIC DISEASES; CRICETINAE; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; HANTAVIRUS PULMONARY SYNDROME; SIN NOMBRE VIRUS; VIRUS REPLICATION;

ANDES VIRUS; ANIMALIA; CRICETINAE; HANTAVIRUS; SIN NOMBRE VIRUS;

EID: 84875763422     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03291-12     Document Type: Article

References (14)

1. Botten J, Mirowsky K, Kusewitt D, Bharadwaj M, Yee J, Ricci R, Feddersen RM, Hjelle B. 2000. Experimental infection model for Sin Nombre hantavirus in the deer mouse (Peromyscus maniculatus). Proc. Natl. Acad. Sci. U. S. A. 97:10578-10583.
2. Medina RA, Mirowsky-Garcia K, Hutt J, Hjelle B. 2007. Ribavirin, human convalescent plasma and anti-beta3 integrin antibody inhibit infection by Sin Nombre virus in the deer mouse model. J. Gen. Virol. 88:493-505.
3. Safronetz D, Ebihara H, Feldmann H, Hooper JW. 2012. The Syrian hamster model of hantavirus pulmonary syndrome. Antivir. Res. 95:282-292.
4. Hooper JW, Larsen T, Custer DM, Schmaljohn CS. 2001. A lethal disease model for hantavirus pulmonary syndrome. Virology 289:6-14.
5. Eyzaguirre EJ, Milazzo ML, Koster FT, Fulhorst CF. 2008. Choclo virus infection in the Syrian golden hamster. Am. J. Trop. Med. Hyg. 78:669-674.
6. Sanada T, Kariwa H, Nagata N, Tanikawa Y, Seto T, Yoshimatsu K, Arikawa J, Yoshii K, Takashima I. 2011. Puumala virus infection in Syrian hamsters (Mesocricetus auratus) resembling hantavirus infection in natural rodent hosts. Virus Res. 160:108-119.
7. Milazzo ML, Eyzaguirre EJ, Molina CP, Fulhorst CF. 2002. Maporal viral infection in the Syrian golden hamster: a model of hantavirus pulmonary syndrome. J. Infect. Dis. 186:1390-1395.
8. Wahl-Jensen V, Chapman J, Asher L, Fisher R, Zimmerman M, Larsen T, Hooper JW. 2007. Temporal analysis of Andes virus and Sin Nombre virus infections of Syrian hamsters. J. Virol. 81:7449-7462.
9. Safronetz D, Zivcec M, Lacasse R, Feldmann F, Rosenke R, Long D, Haddock E, Brining D, Gardner D, Feldmann H, Ebihara H. 2011. Pathogenesis and host response in Syrian hamsters following intranasal infection with Andes virus. PLoS Pathog. 7:e1002426. doi:10.1371/journal .ppat.1002426.
10. Wang F, Flanagan J, Su N, Wang LC, Bui S, Nielson A, Wu X, Vo HT, Ma XJ, Luo Y. 2012. RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues. J. Mol. Diagn. 14:22-29.
11. Jonsson CB, Hooper J, Mertz G. 2008. Treatment of hantavirus pulmonary syndrome. Antivir. Res. 78:162-169.
12. Macneil A, Nichol ST, Spiropoulou CF. 2011. Hantavirus pulmonary syndrome. Virus Res. 162:138-147.
13. McElroy AK, Smith JM, Hooper JW, Schmaljohn CS. 2004. Andes virus Mgenome segment is not sufficient to confer the virulence associated with Andes virus in Syrian hamsters. Virology 326:130-139.
14. Brown KS, Ebihara H, Feldmann H. 2012. Development of a minigenome system for Andes virus, a New World hantavirus. Arch. Virol. 157: 2227-2233.