Deregulation of protein methylation in melanoma

European Journal of Cancer

Volumn 49, Issue 6, 2013, Pages 1305-1313

  Limm, Katharina ^a   Ott, Corinna ^a   Wallner, Susanne ^a   Mueller, Daniel W ^a   Oefner, Peter ^a   Hellerbrand, Claus ^b   Bosserhoff, Anja Katrin ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

MAPK ERK signalling; Melanoma; Methylthioadenosine; PRMT; Protein arginine methylation

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 4; PROTEIN ARGININE METHYLTRANSFERASE 6; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DEREGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MELANOMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN METHYLATION; PROTEIN PHOSPHORYLATION;

ARGININE; CELL LINE, TUMOR; DEOXYADENOSINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MELANOMA; METHYLATION; NUCLEAR PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-ARGININE N-METHYLTRANSFERASES; PURINE-NUCLEOSIDE PHOSPHORYLASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THIONUCLEOSIDES;

EID: 84875743357     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.11.026     Document Type: Article

References (34)

1. Y.H. Lee, and M.R. Stallcup Minireview: protein arginine methylation of nonhistone proteins in transcriptional regulation Mol Endocrinol 23 2009 425 433
2. B. Chang, Y. Chen, Y. Zhao, and R.K. Bruick JMJD6 is a histone arginine demethylase Science 318 2007 444 447
3. S.S. Wolf The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans Cell Mol Life Sci 66 2009 2109 2121
4. M.T. Bedford, and S.G. Clarke Protein arginine methylation in mammals: who, what, and why Mol Cell 33 2009 1 13
5. Y.R. Kim, B.K. Lee, and R.Y. Park Differential CARM1 expression in prostate and colorectal cancers BMC Cancer 10 2010 197
6. H. Hong, C. Kao, and M.H. Jeng Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status Cancer 101 2004 83 89
7. K. Mathioudaki, A. Scorilas, and A. Ardavanis Clinical evaluation of PRMT1 gene expression in breast cancer Tumour Biol 32 2011 575 582
8. J.H. Cho, M.K. Lee, K.W. Yoon, J. Lee, S.G. Cho, and E.J. Choi Arginine methylation-dependent regulation of ASK1 signaling by PRMT1 Cell Death Differ 19 2011 859 870
9. M.A. Powers, M.M. Fay, R.E. Factor, A.L. Welm, and K.S. Ullman Protein arginine methyltransferase 5 accelerates tumor growth by arginine methylation of the tumor suppressor programmed cell death 4 Cancer Res 71 2011 5579 5587
10. L. Wang, S. Pal, and S. Sif Protein arginine methyltransferase 5 suppresses the transcription of the RB family of tumor suppressors in leukemia and lymphoma cells Mol Cell Biol 28 2008 6262 6277
11. J.H. Lim, Y.J. Choi, C.H. Cho, and J.W. Park Protein arginine methyltransferase 5 is an essential component of the hypoxia-inducible factor 1 signaling pathway Biochem Biophys Res Commun 418 2012 254 259
12. V. Karkhanis, Y.J. Hu, R.A. Baiocchi, A.N. Imbalzano, and S. Sif Versatility of PRMT5-induced methylation in growth control and development Trends Biochem Sci 36 2011 633 641
13. M. Jansson, S.T. Durant, and E.C. Cho Arginine methylation regulates the p53 response Nat Cell Biol 10 2008 1431 1439
14. H.G. Williams-Ashman, J. Seidenfeld, and P. Galletti Trends in the biochemical pharmacology of 5′-deoxy-5′-methylthioadenosine Biochem Pharmacol 31 1982 277 288
15. P.A. Maher Inhibition of the tyrosine kinase activity of the fibroblast growth factor receptor by the methyltransferase inhibitor 5′- methylthioadenosine J Biol Chem 268 1993 4244 4249
16. G. Kirovski, A.P. Stevens, and B. Czech Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5′-deoxy-5′-methylthioadenosine (MTA) Am J Pathol 178 2011 1145 1152
17. A.P. Stevens, B. Spangler, and S. Wallner Direct and tumor microenvironment mediated influences of 5′-deoxy-5′-(methylthio) adenosine on tumor progression of malignant melanoma J Cell Biochem 106 2009 210 219
18. C. Hellerbrand, M. Muhlbauer, and S. Wallner Promoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma Carcinogenesis 27 2006 64 72
19. I. Behrmann, S. Wallner, and W. Komyod Characterization of methylthioadenosin phosphorylase (MTAP) expression in malignant melanoma Am J Pathol 163 2003 683 690
20. S. Meyer, P.J. Wild, and T. Vogt Methylthioadenosine phosphorylase represents a predictive marker for response to adjuvant interferon therapy in patients with malignant melanoma Exp Dermatol 19 2010 e251 e257
21. C.C. Collins, S.V. Volik, and A. Lapuk Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenine phosphorylase, an exploitable tumor target Mol Cancer Ther 11 2012 775 783
22. J. Kim, M.A. Kim, S.Y. Min, C.D. Jee, H.E. Lee, and W.H. Kim Downregulation of methylthioadenosin phosphorylase by homozygous deletion in gastric carcinoma Genes Chromosomes Cancer 50 2011 421 433
23. S.A. Coulthard, C.P. Redfern, and S. Vikingsson Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers Mol Cancer Ther 10 2011 495 504
24. B. Spangler, M. Kappelmann, and B. Schittek ETS-1/RhoC signaling regulates the transcription factor c-Jun in melanoma Int J Cancer 130 2012 2801 2811
25. S. Schiffner, N. Zimara, R. Schmid, and A.K. Bosserhoff P54nrb is a new regulator of progression of malignant melanoma Carcinogenesis 32 2011 1176 1182
26. S. Braig, S. Wallner, B. Junglas, R. Fuchshofer, and A.K. Bosserhoff CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration Br J Cancer 105 2011 231 238
27. J. Schmidt, K. Friebel, R. Schonherr, M.G. Coppolino, and A.K. Bosserhoff Migration-associated secretion of melanoma inhibitory activity at the cell rear is supported by KCa3.1 potassium channels Cell Res 20 2010 1224 1238
28. P. Andreu-Perez, R. Esteve-Puig, and C. Torre-Minguela Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF Sci Signal 4 2011 ra58
29. M. Al Dhaheri, J. Wu, and G.P. Skliris CARM1 is an important determinant of ERalpha-dependent breast cancer cell differentiation and proliferation in breast cancer cells Cancer Res 71 2011 2118 2128
30. C.Y. Ou, M.J. LaBonte, and P.C. Manegold A coactivator role of CARM1 in the dysregulation of beta-catenin activity in colorectal cancer cell growth and gene expression Mol Cancer Res 9 2011 660 670
31. F. Watanabe, M. Takao, and K. Inoue Immunohistochemical diagnosis of methylthioadenosine phosphorylase (MTAP) deficiency in non-small cell lung carcinoma Lung Cancer 63 2009 39 44
32. A.L. Subhi, B. Tang, and B.R. Balsara Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer Clin Cancer Res 10 2004 7290 7296
33. A.P. Stevens, K. Dettmer, and G. Kirovski Quantification of intermediates of the methionine and polyamine metabolism by liquid chromatography-tandem mass spectrometry in cultured tumor cells and liver biopsies J Chromatogr A 1217 2010 3282 3288
34. S. Jayne, K.M. Rothgiesser, and M.O. Hottiger CARM1 but not its enzymatic activity is required for transcriptional coactivation of NF-kappaB-dependent gene expression J Mol Biol 394 2009 485 495