Surgery in asymptomatic patients with colorectal cancer and unresectable liver metastases: The authors' experience

OncoTargets and Therapy

Volumn 6, Issue , 2013, Pages 267-272

  Boselli, Carlo ^a   Renzi, Claudio ^a   Gemini, Alessandro ^a   Castellani, Elisa ^a   Trastulli, Stefano ^a   Desiderio, Jacopo ^a   Corsi, Alessia ^a   Barberini, Francesco ^a   Cirocchi, Roberto ^a   Santoro, Alberto ^b   Parisi, Amilcare ^c   Redler, Adriano ^b   Noya, Giuseppe ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c St Maria Hospital   (Italy)

Author keywords

30 day mortality; Inoperable liver replacement; Large bowel; Palliative surgery; Tumor

Indexed keywords

BEVACIZUMAB; FLUOROURACIL; FOLINIC ACID; OXALIPLATIN;

ADULT; AGED; ARTICLE; CANCER MORTALITY; CANCER PALLIATIVE THERAPY; CANCER PROGNOSIS; CLINICAL ARTICLE; COLORECTAL CANCER; COLORECTAL SURGERY; ELECTIVE SURGERY; HUMAN; LIVER METASTASIS; OVERALL SURVIVAL; RISK ASSESSMENT; TREATMENT OUTCOME;

EID: 84875739671     PISSN: 11786930     EISSN: None     Source Type: Journal    
DOI: 10.2147/OTT.S39448     Document Type: Article

References (32)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55(2):74-108.
2. Edwards BK, Ward E, Kohler BA, et al. Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer. 2010;116(3):544-573.
3. Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, Boyle P. Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol. 2007;18(3):581-592.
4. Manfredi S, Lepage C, Hatem C, Coatmeur O, Faivre J, Bouvier AM. Epidemiology and management of liver metastases from colorectal cancer. Ann Surg. 2006;244(2):254-259.
5. Simmonds PC, Primrose JN, Colquitt JL, Garden OJ, Poston GJ, Rees M. Surgical resection of hepatic metastases from colorectal cancer: a systematic review of published studies. Br J Cancer. 2006;94(7): 982-999.
6. Dawson LE, Russell AH, Tong D, Wisbeck WM. Adenocarcinoma of the sigmoid colon: sites of initial dissemination and clinical patterns of recurrence following surgery alone. J Surg Oncol. 1983;22(2):95-99.
7. Chu DZ, Lang NP, Thomson C, Osteen PC, Westbrook KC. Peritoneal carcinomatosis in nongynecologic malignancy: a prospective study of prognostic factors. Cancer. 1989;63(2):364-367.
8. Inoue M, Ohta M, Iuchi K, et al. Benefits of surgery for patients with pulmonary metastases from colorectal carcinoma. Ann Thorac Surg. 2004;78(1):238-244.
9. Lucena JR. Reseccion de metastasis pulmonares en cancer colorectal [Resection of lung metastases from colorectal cancer]. Cir Esp. 2005;78(6):362-365. Spanish.
10. Iwasaki A, Shirakusa T, Yamashita Y, Noritomi T, Maekawa T, Hamada T. Characteristic differences between patients who have undergone surgical treatment for lung metastasis or hepatic metastasis from colorectal cancer. Thorac Cardiovasc Surg. 2005;53(6):358-364.
11. Van Cutsem E, Nordlinger B, Cervantes A. Advanced colorectal cancer: ESMO clinical practice guidelines for treatment. Ann Oncol. 2010;21(Suppl 5):v93-v97.
12. Cirocchi R, Trastulli S, Boselli C,et al. Radiofrequency ablation in the treatment of liver metastases from colorectal cancer [review]. Cochrane Database Syst Rev. 2012;6:CD006317.
13. McCahill LE, Yothers GA, Sharif S, et al. A phase II trial of 5-fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) chemotherapy plus bevacizumab (bev) for patients (pts) with unresectable stage IV colon cancer and a synchronous asymptomatic primary tumor: results of NSABP C-10 [abstract]. J Clin Oncol. 2010;28(15 Suppl):3527.
14. Bokemeyer C, Kohne C, Rougier P, Stroh C, Schlichting M, Van Cutsem E. Cetuximab with chemotherapy (CT) as first-line treatment for metastatic colorectal cancer (mCRC): analysis of the CRYSTAL and OPUS studies according to KRAS and BRAF mutation status [abstract]. J Clin Oncol. 2010;28(Suppl 15):3506.
15. Ocvirk J, Brodowicz T, Wrba F, et al. Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial. World J Gastroenterol. 2010;16(25):3133-3143.
16. Costi R, Di Mauro D, Giordano P, et al. Impact of palliative chemotherapy and surgery on management of stage IV incurable colorectal cancer. Ann Surg Oncol. 2010;17(2):432-440.
17. Poultsides GA, Servais EL, Saltz LB, et al. Outcome of primary tumor in patients with synchronous stage IV colorectal cancer receiving combination chemotherapy without surgery as initial treatment. J Clin Oncol. 2009;27(20):3379-3384.
18. Karoui M, Soprani A, Charachon A, et al. Primary chemotherapy with or without colonic stent for management of unresectable stage IV colorectal cancer. Eur J Surg Oncol. 2010;36(1):58-64.
19. Cirocchi R, Farinella E, Trastulli S, et al. Safety and efficacy of endoscopic colonic stenting as a bridge to surgery in the management of intestinal obstruction due to left colon and rectal cancer: a systematic review and meta-analysis. Surg Oncol. 2013;22(1):14-21.
20. Damjanov N, Weiss J, Haller DG. Resection of the primary colorectal cancer is not necessary in nonobstructed patients with metastatic disease. Oncologist. 2009;14(10):963-969.
21. Dripps RD. New classification of physical status. Anesthesiology. 1963;24:111.
22. Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5(6):649-655.
23. Muratore A, Zorzi D, Bouzari H, et al. Asymptomatic colorectal cancer with un-resectable liver metastases: immediate colorectal resection or up-front systemic chemotherapy? Ann Surg Oncol. 2007;14(2):766-770.
24. Benoist S, Pautrat K, Mitry E, Rougier P, Penna C, Nordlinger B. Treatment strategy for patients with colorectal cancer and synchronous irresectable liver metastases. Br J Surg. 2005;92(9):1155-1160.
25. Galizia G, Lieto E, Orditura M, et al. First-line chemotherapy vs bowel tumor resection plus chemotherapy for patients with unresectable synchronous colorectal hepatic metastases. Arch Surg. 2008;143(4):352-358.
26. Konyalian VR, Rosing DK, Haukoos JS, et al. The role of primary tumour resection in patients with stage IV colorectal cancer. Colorectal Dis. 2007;9(5):430-437.
27. Kleespies A, Fuessl KE, Seelinger H, et al. Determinants of morbidity and survival after elective non-curative resection of stage IV colon and rectal cancer. Int J Colorectal Dis. 2009;24(9):1097-1109.
28. Mik M, Dziki L, Galbfach P, Trzcinski R, Sygut A, Dziki A. Resection of the primary tumour or other palliative procedures in incurable IV stage colorectal cancer patients? Colorectal Dis. 2010; 12(7 Online):e61-e67.
29. Stillwell AP, Ho YH, Veitch C. Systematic review of prognostic factors related to overall survival in patients with stage IV colorectal cancer and unresectable metastases. World J Surg. 2011;35(3):684-692.
30. Katoh H, Yamashita K, Kokuba Y, et al. Surgical resection of stage IV colorectal cancer and prognosis. World J Surg. 2008;32(6):1130-1137.
31. Tebbutt NC, Norman AR, Cunningham D, et al. Intestinal complications after chemotherapy for patients with unresected primary colorectal cancer and synchronous metastases. Gut. 2003;52(4):568-573.
32. Cirocchi R, Trastulli S, Abraha I, et al. Non-resection versus resection for an asymptomatic primary tumour in patients with unresectable stage IV colorectal cancer [review]. Cochrane Database Syst Rev. 2012;8:CD008997.