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Volumn 18, Issue 7-8, 2013, Pages 331-336

Torching the Haystack: Modelling fast-fail strategies in drug development

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DRUG COST; DRUG DEVELOPMENT; DRUG FORMULATION; DRUG INDUSTRY; DRUG MARKETING; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT;

EID: 84875739614     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2012.11.011     Document Type: Short Survey
Times cited : (12)

References (10)
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    • More haste, less development speed
    • D. Lendrem More haste, less development speed Scrip Mag. 1995 22 23
    • (1995) Scrip Mag. , pp. 22-23
    • Lendrem, D.1
  • 2
    • 0032721152 scopus 로고    scopus 로고
    • Alternative strategies in drug development: Clinical pharmacological aspects
    • J. Kuhlmann Alternative strategies in drug development: clinical pharmacological aspects Int. J. Clin. Pharmacol. Ther. 37 1999 575 583
    • (1999) Int. J. Clin. Pharmacol. Ther. , vol.37 , pp. 575-583
    • Kuhlmann, J.1
  • 3
    • 33947691728 scopus 로고    scopus 로고
    • Driving earlier clinical attrition: if you want to find the needle, burn down the haystack. Considerations for biomarker development
    • DOI 10.1016/j.drudis.2007.02.004, PII S1359644607000566
    • R. Peck Driving earlier clinical attrition; if you want to find the needle, burn down the Haystack Drug Discov. Today 12 2007 289 294 (Pubitemid 46486663)
    • (2007) Drug Discovery Today , vol.12 , Issue.7-8 , pp. 289-294
    • Peck, R.W.1
  • 4
    • 84888280580 scopus 로고    scopus 로고
    • Quick win, fast fail
    • C. Clarke Quick win, fast fail Int. Clin. Trials 13 2010 142
    • (2010) Int. Clin. Trials , vol.13 , pp. 142
    • Clarke, C.1
  • 5
    • 77649234756 scopus 로고    scopus 로고
    • How to improve R&D productivity
    • S. Paul How to improve R&D productivity Nat. Rev. Drug Discov. 9 2010 203 214
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 203-214
    • Paul, S.1
  • 6
    • 0030449652 scopus 로고    scopus 로고
    • Some statistical issues in project prioritization in the pharmaceutical industry
    • S.J. Senn Some statistical issues in project prioritization in the pharmaceutical industry Stat. Med. 15 1996 2689 2702
    • (1996) Stat. Med. , vol.15 , pp. 2689-2702
    • Senn, S.J.1
  • 7
    • 84875692383 scopus 로고    scopus 로고
    • Stochastic models for the planning of pharmaceutical research
    • J.C. Gittins Stochastic models for the planning of pharmaceutical research J. Stat. Theory Appl. 2 2003 198 214
    • (2003) J. Stat. Theory Appl. , vol.2 , pp. 198-214
    • Gittins, J.C.1
  • 8
    • 34548324706 scopus 로고    scopus 로고
    • The cost of biopharmaceutical R&D; Is biotech different?
    • J.A. DiMasi, and H.G. Grabowski The cost of biopharmaceutical R&D; is biotech different? Manage. Decis. Econ. 28 2007 469 479
    • (2007) Manage. Decis. Econ. , vol.28 , pp. 469-479
    • Dimasi, J.A.1    Grabowski, H.G.2
  • 9
    • 84927978861 scopus 로고    scopus 로고
    • The pharmaceutical sector
    • L.R. Burns, University Press
    • J. Northrup The pharmaceutical sector L.R. Burns, The Business of Healthcare Innovation 2005 University Press 27 102
    • (2005) The Business of Healthcare Innovation , pp. 27-102
    • Northrup, J.1
  • 10
    • 15844411320 scopus 로고    scopus 로고
    • Moving statistics beyond the individual clinical trial: Applying decision science to optimize a clinical development plan
    • DOI 10.1002/pst.149
    • S.A. Julious, and D.J. Swank Moving statistics beyond the individual clinical trial: applying decision science to optimize a clinical development plan Pharm. Stat. 4 2005 37 46 (Pubitemid 40425994)
    • (2005) Pharmaceutical Statistics , vol.4 , Issue.1 , pp. 37-46
    • Julious, S.A.1    Swank, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.