Novel semisynthetic antibiotics from caprazamycins A-G: Caprazene derivatives and their antibacterial activity

Journal of Antibiotics

Volumn 66, Issue 3, 2013, Pages 171-178

  Takahashi, Yoshiaki ^a   Igarashi, Masayuki ^b   Miyake, Toshiaki ^a   Soutome, Hiromi ^a   Ishikawa, Kanae ^a   Komatsuki, Yasuhiro ^a   Koyama, Yoshiko ^a   Nakagawa, Naoko ^b   Hattori, Seiko ^b   Inoue, Kunio ^b   Doi, Norio ^c   Akamatsu, Yuzuru ^b  

^a Institute of Microbial Chemistry (BIKAKEN) Hiyoshi   (Japan)

^b INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

^c RESEARCH INSTITUTE OF TUBERCULOSIS   (Japan)

Author keywords

acid fast bacteria; antibacterial activity; caprazamycin; caprazene; CPZEN 45; mycobacteria; tuberculosis

Indexed keywords

ANTIBIOTIC AGENT; ANTIMYCOBACTERIAL AGENT; CAPRAZAMYCIN A; CAPRAZAMYCIN B; CAPRAZAMYCIN C; CAPRAZAMYCIN D; CAPRAZAMYCIN E; CAPRAZAMYCIN F; CAPRAZAMYCIN G; CAPRAZENE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CHEMICAL MODIFICATION; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PARTIAL DRUG SYNTHESIS; PRIORITY JOURNAL; TUBERCULOSIS;

ANTI-BACTERIAL AGENTS; AZEPINES; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; LIPIDS; MYCOBACTERIUM AVIUM; MYCOBACTERIUM TUBERCULOSIS; NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP; URIDINE;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS; NEGIBACTERIA; POSIBACTERIA;

EID: 84875723294     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2013.9     Document Type: Article

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