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Volumn 18, Issue 7-8, 2013, Pages 399-406

Brain tumor immunotherapy: Seeing the brain in the body

Author keywords

[No Author keywords available]

Indexed keywords

ADOPTIVE TRANSFER; BLOOD BRAIN BARRIER; BRAIN METASTASIS; BRAIN TUMOR; CANCER IMMUNIZATION; CANCER IMMUNOTHERAPY; CANCER LOCALIZATION; CANCER RESISTANCE; GLIOBLASTOMA; HUMAN; IMMUNE RESPONSE; IMMUNOREGULATION; PASSIVE IMMUNIZATION; REVIEW;

EID: 84875705324     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2012.11.007     Document Type: Review
Times cited : (10)

References (60)
  • 1
    • 69949148057 scopus 로고    scopus 로고
    • Immunotherapy of diffuse gliomas: Biological background, current status and future developments
    • O.M. Grauer Immunotherapy of diffuse gliomas: biological background, current status and future developments Brain Pathol. 19 2009 674 693
    • (2009) Brain Pathol. , vol.19 , pp. 674-693
    • Grauer, O.M.1
  • 2
    • 69949142058 scopus 로고    scopus 로고
    • Dendritic cell therapy of high-grade gliomas
    • S. Van Gool Dendritic cell therapy of high-grade gliomas Brain Pathol. 19 2009 694 712
    • (2009) Brain Pathol. , vol.19 , pp. 694-712
    • Van Gool, S.1
  • 3
    • 77953636869 scopus 로고    scopus 로고
    • Dendritic cell vaccines to combat glioblastoma
    • C.J. Wheeler Dendritic cell vaccines to combat glioblastoma Exp. Rev. Neurother. 10 2010 483 486
    • (2010) Exp. Rev. Neurother. , vol.10 , pp. 483-486
    • Wheeler, C.J.1
  • 4
    • 58849163070 scopus 로고    scopus 로고
    • Targeted therapy for neuro-oncology: Reviewing the menu
    • L.A. Lampson Targeted therapy for neuro-oncology: reviewing the menu Drug Discov. Today 14 2009 185 191
    • (2009) Drug Discov. Today , vol.14 , pp. 185-191
    • Lampson, L.A.1
  • 5
    • 77957370161 scopus 로고    scopus 로고
    • Development of an EGFRvIII specific recombinant antibody
    • P. Gupta Development of an EGFRvIII specific recombinant antibody BMC Biotechnol. 10 2010 72
    • (2010) BMC Biotechnol. , vol.10 , pp. 72
    • Gupta, P.1
  • 6
    • 74549196076 scopus 로고    scopus 로고
    • HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors
    • N. Ahmed HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumors Clin. Cancer Res. 16 2010 474 485
    • (2010) Clin. Cancer Res. , vol.16 , pp. 474-485
    • Ahmed, N.1
  • 7
    • 77957606517 scopus 로고    scopus 로고
    • Successful treatment of melanoma brain metastases with adoptive cell therapy
    • J.J. Hong Successful treatment of melanoma brain metastases with adoptive cell therapy Clin. Cancer Res. 16 2010 4892 4898
    • (2010) Clin. Cancer Res. , vol.16 , pp. 4892-4898
    • Hong, J.J.1
  • 8
    • 79952726291 scopus 로고    scopus 로고
    • Monoclonal antibodies in neuro-oncology: Getting past the blood-brain barrier
    • L.A. Lampson Monoclonal antibodies in neuro-oncology: getting past the blood-brain barrier MAbs 3 2011 153 160
    • (2011) MAbs , vol.3 , pp. 153-160
    • Lampson, L.A.1
  • 9
    • 77954167987 scopus 로고    scopus 로고
    • Treatment and prevention of secondary CNS lymphoma
    • S. Nagpal Treatment and prevention of secondary CNS lymphoma Semin. Neurol. 30 2010 263 272
    • (2010) Semin. Neurol. , vol.30 , pp. 263-272
    • Nagpal, S.1
  • 10
    • 41949105576 scopus 로고    scopus 로고
    • An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain
    • V. Voelter An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain Cancer Immun. 8 2008 6
    • (2008) Cancer Immun. , vol.8 , pp. 6
    • Voelter, V.1
  • 11
    • 79951848084 scopus 로고    scopus 로고
    • Antigen spreading contributes to MAGE vaccination-induced regression of melanoma metastases
    • V. Corbiere Antigen spreading contributes to MAGE vaccination-induced regression of melanoma metastases Cancer Res. 71 2011 1253 1262
    • (2011) Cancer Res. , vol.71 , pp. 1253-1262
    • Corbiere, V.1
  • 12
    • 78751524881 scopus 로고    scopus 로고
    • Interindividual variability of response to rituximab: From biological origins to individualized therapies
    • G. Cartron Interindividual variability of response to rituximab: from biological origins to individualized therapies Clin. Cancer Res. 17 2011 19 30
    • (2011) Clin. Cancer Res. , vol.17 , pp. 19-30
    • Cartron, G.1
  • 13
    • 78349252105 scopus 로고    scopus 로고
    • Overview of cellular immunotherapy for patients with glioblastoma
    • 10.1155/2010/689171
    • E. Vauleon Overview of cellular immunotherapy for patients with glioblastoma Clin. Dev. Immunol. 2010 10.1155/2010/689171
    • (2010) Clin. Dev. Immunol.
    • Vauleon, E.1
  • 14
    • 84875729964 scopus 로고    scopus 로고
    • Brain tumor models to predict clinical outcome: Like the phoenix?
    • R.M. Murillo, A. Martinez, Humana
    • L.A. Lampson Brain tumor models to predict clinical outcome: like the phoenix? R.M. Murillo, A. Martinez, Animal Models of Brain Tumors 2013 Humana
    • (2013) Animal Models of Brain Tumors
    • Lampson, L.A.1
  • 15
    • 77958497844 scopus 로고    scopus 로고
    • T-cell immunotherapy for malignant glioma: Toward a combined approach
    • P.Y. Dietrich T-cell immunotherapy for malignant glioma: toward a combined approach Curr. Opin. Oncol. 22 2010 604 610
    • (2010) Curr. Opin. Oncol. , vol.22 , pp. 604-610
    • Dietrich, P.Y.1
  • 16
    • 77956070565 scopus 로고    scopus 로고
    • Anti-HER2 vaccines: New prospects for breast cancer therapy
    • M.Z. Ladjemi Anti-HER2 vaccines: new prospects for breast cancer therapy Cancer Immunol. Immunother. 59 2010 1295 1312
    • (2010) Cancer Immunol. Immunother. , vol.59 , pp. 1295-1312
    • Ladjemi, M.Z.1
  • 17
    • 77956016081 scopus 로고    scopus 로고
    • Am"B"valent: Anti-CD20 antibodies unravel the dual role of B cells in immunopathogenesis
    • O. Thaunat Am"B"valent: anti-CD20 antibodies unravel the dual role of B cells in immunopathogenesis Blood 116 2010 515 521
    • (2010) Blood , vol.116 , pp. 515-521
    • Thaunat, O.1
  • 18
    • 0042982183 scopus 로고    scopus 로고
    • Basic principles of CNS immunology
    • H.R. Winn, Saunders
    • L.A. Lampson Basic principles of CNS immunology H.R. Winn, Youman's Neurological Surgery 2003 Saunders 673 688
    • (2003) Youman's Neurological Surgery , pp. 673-688
    • Lampson, L.A.1
  • 19
    • 0032752574 scopus 로고    scopus 로고
    • Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation
    • DOI 10.1016/S0165-5728(99)00130-7, PII S0165572899001307
    • C.J. Harling-Berg Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation J. Neuroimmunol. 101 1999 111 127 (Pubitemid 29516453)
    • (1999) Journal of Neuroimmunology , vol.101 , Issue.2 , pp. 111-127
    • Harling-Berg, C.J.1    Park, J.T.2    Knopf, P.M.3
  • 20
    • 79957899037 scopus 로고    scopus 로고
    • The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system
    • E.K. Rainey-Barger The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system Brain Behav. Immun. 25 2011 922931
    • (2011) Brain Behav. Immun. , vol.25 , pp. 922931
    • Rainey-Barger, E.K.1
  • 21
    • 58149352396 scopus 로고    scopus 로고
    • Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis
    • J.V. Kim Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis Nature 457 2009 191 195
    • (2009) Nature , vol.457 , pp. 191-195
    • Kim, J.V.1
  • 22
    • 82355190262 scopus 로고    scopus 로고
    • Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis
    • F. Pfeiffer Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis Acta Neuropathol. 122 2011 601 614
    • (2011) Acta Neuropathol. , vol.122 , pp. 601-614
    • Pfeiffer, F.1
  • 23
    • 84857466255 scopus 로고    scopus 로고
    • Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs
    • J. Van den Bossche Regulation and function of the E-cadherin/catenin complex in cells of the monocyte-macrophage lineage and DCs Blood 119 2012 1623 1633
    • (2012) Blood , vol.119 , pp. 1623-1633
    • Van Den Bossche, J.1
  • 25
    • 56149123447 scopus 로고    scopus 로고
    • 1 T cells targeting a single immunodominant epitope are sufficient for elimination of established SV40T antigen-induced brain tumors
    • 1 T cells targeting a single immunodominant epitope are sufficient for elimination of established SV40T antigen-induced brain tumors J. Immunol. 181 2008 4406 4417
    • (2008) J. Immunol. , vol.181 , pp. 4406-4417
    • Tatum, A.M.1
  • 26
    • 84255197842 scopus 로고    scopus 로고
    • Cancer immunotherapy comes of age
    • I. Mellman Cancer immunotherapy comes of age Nature 480 2011 480 489
    • (2011) Nature , vol.480 , pp. 480-489
    • Mellman, I.1
  • 27
    • 77953718858 scopus 로고    scopus 로고
    • Biomaterial-based technologies for brain anti-cancer therapeutics and imaging
    • G. Orive Biomaterial-based technologies for brain anti-cancer therapeutics and imaging Biochim. Biophys. Acta 1806 2010 96 107
    • (2010) Biochim. Biophys. Acta , vol.1806 , pp. 96-107
    • Orive, G.1
  • 28
    • 62149102209 scopus 로고    scopus 로고
    • Tumour vaccine approaches for CNS malignancies: Progress to date
    • J.D. Ebben Tumour vaccine approaches for CNS malignancies: progress to date Drugs 69 2009 241 249
    • (2009) Drugs , vol.69 , pp. 241-249
    • Ebben, J.D.1
  • 29
    • 67349223911 scopus 로고    scopus 로고
    • Dendritic-cell- and peptide-based vaccination strategies for glioma
    • discussion 273
    • R. Yamanaka Dendritic-cell- and peptide-based vaccination strategies for glioma Neurosurg. Rev. 32 2009 265 273 discussion 273
    • (2009) Neurosurg. Rev. , vol.32 , pp. 265-273
    • Yamanaka, R.1
  • 30
    • 79956119017 scopus 로고    scopus 로고
    • Regional and mucosal memory T cells
    • B.S. Sheridan, and L. Lefrancois Regional and mucosal memory T cells Nat. Immunol. 12 2011 485 491
    • (2011) Nat. Immunol. , vol.12 , pp. 485-491
    • Sheridan, B.S.1    Lefrancois, L.2
  • 31
    • 44849083915 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells
    • F.A. Schildberg Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells Eur. J. Immunol. 38 2008 957 967
    • (2008) Eur. J. Immunol. , vol.38 , pp. 957-967
    • Schildberg, F.A.1
  • 32
    • 33748754933 scopus 로고    scopus 로고
    • The importance of regional lymph nodes for mucosal tolerance
    • DOI 10.1111/j.1600-065X.2006.00429.x
    • G. Kraal The importance of regional lymph nodes for mucosal tolerance Immunol. Rev. 213 2006 119 130 (Pubitemid 44401497)
    • (2006) Immunological Reviews , vol.213 , Issue.1 , pp. 119-130
    • Kraal, G.1    Samsom, J.N.2    Mebius, R.E.3
  • 33
    • 73349104433 scopus 로고    scopus 로고
    • What role does the route of immunization play in the generation of protective immunity against mucosal pathogens?
    • I.M. Belyakov, and J.D. Ahlers What role does the route of immunization play in the generation of protective immunity against mucosal pathogens? J. Immunol. 183 2009 6883 6892
    • (2009) J. Immunol. , vol.183 , pp. 6883-6892
    • Belyakov, I.M.1    Ahlers, J.D.2
  • 34
    • 61549119830 scopus 로고    scopus 로고
    • Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes
    • T. Calzascia Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes Glia 56 2008 1625 1636
    • (2008) Glia , vol.56 , pp. 1625-1636
    • Calzascia, T.1
  • 35
    • 45849084617 scopus 로고    scopus 로고
    • Experimental manipulations of afferent immune responses influence efferent immune responses to brain tumors
    • D.L. Thomas Experimental manipulations of afferent immune responses influence efferent immune responses to brain tumors Cancer Immunol. Immunother. 57 2008 1323 1333
    • (2008) Cancer Immunol. Immunother. , vol.57 , pp. 1323-1333
    • Thomas, D.L.1
  • 37
    • 70349097179 scopus 로고    scopus 로고
    • Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice
    • L. Zhang Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice Glia 57 2009 1458 1467
    • (2009) Glia , vol.57 , pp. 1458-1467
    • Zhang, L.1
  • 38
    • 34548505262 scopus 로고    scopus 로고
    • + T cell responses to HLA class I-restricted wild-type sequence p53 peptides
    • DOI 10.1016/j.clim.2007.05.015, PII S1521661607012259
    • K. Sakakura Toward the development of multi-epitope p53 cancer vaccines: an in vitro assessment of CD8(+) T cell responses to HLA class I-restricted wild-type sequence p53 peptides Clin. Immunol. 125 2007 43 51 (Pubitemid 47374535)
    • (2007) Clinical Immunology , vol.125 , Issue.1 , pp. 43-51
    • Sakakura, K.1    Chikamatsu, K.2    Furuya, N.3    Appella, E.4    Whiteside, T.L.5    DeLeo, A.B.6
  • 39
    • 77951255945 scopus 로고    scopus 로고
    • Natural immunity to cancer in humans
    • G. Bindea Natural immunity to cancer in humans Curr. Opin. Immunol. 22 2010 215 222
    • (2010) Curr. Opin. Immunol. , vol.22 , pp. 215-222
    • Bindea, G.1
  • 40
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • S.I. Grivennikov Immunity, inflammation, and cancer Cell 140 2010 883 899
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1
  • 41
    • 77956934564 scopus 로고    scopus 로고
    • Manipulation of regulatory T-cell function by immunomodulators: A boon or a curse?
    • M.M. Fort, and P.K. Narayanan Manipulation of regulatory T-cell function by immunomodulators: a boon or a curse? Toxicol. Sci. 117 2010 253 262
    • (2010) Toxicol. Sci. , vol.117 , pp. 253-262
    • Fort, M.M.1    Narayanan, P.K.2
  • 42
    • 77950517325 scopus 로고    scopus 로고
    • The safety and side effects of monoclonal antibodies
    • T.T. Hansel The safety and side effects of monoclonal antibodies Nat. Rev. Drug Discov. 9 2010 325 338
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 325-338
    • Hansel, T.T.1
  • 43
    • 79953816808 scopus 로고    scopus 로고
    • Immunologic biomarkers as correlates of clinical response to cancer immunotherapy
    • M.L. Disis Immunologic biomarkers as correlates of clinical response to cancer immunotherapy Cancer Immunol. Immunother. 60 2011 433 442
    • (2011) Cancer Immunol. Immunother. , vol.60 , pp. 433-442
    • Disis, M.L.1
  • 44
    • 79960393113 scopus 로고    scopus 로고
    • Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells
    • A. Facciabene Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells Nature 475 2011 226 230
    • (2011) Nature , vol.475 , pp. 226-230
    • Facciabene, A.1
  • 45
    • 78149254368 scopus 로고    scopus 로고
    • Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
    • J.H. Sampson Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma J. Clin. Oncol. 28 2010 4722 4729
    • (2010) J. Clin. Oncol. , vol.28 , pp. 4722-4729
    • Sampson, J.H.1
  • 46
    • 0024997449 scopus 로고
    • Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis
    • DOI 10.1002/ana.410280311
    • L.A. Lampson Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis Ann. Neurol. 28 1990 365 372 (Pubitemid 20292623)
    • (1990) Annals of Neurology , vol.28 , Issue.3 , pp. 365-372
    • Lampson, L.A.1    Kushner, P.D.2    Sobel, R.A.3
  • 47
    • 70349275219 scopus 로고    scopus 로고
    • Immune cell-mediated liver injury
    • N. Corazza Immune cell-mediated liver injury Semin. Immunopathol. 31 2009 267 277
    • (2009) Semin. Immunopathol. , vol.31 , pp. 267-277
    • Corazza, N.1
  • 48
    • 78650117181 scopus 로고    scopus 로고
    • Telling apart friend from foe: Discriminating between commensals and pathogens at mucosal sites
    • N. Srinivasan Telling apart friend from foe: discriminating between commensals and pathogens at mucosal sites Innate Immun. 16 2010 391 404
    • (2010) Innate Immun. , vol.16 , pp. 391-404
    • Srinivasan, N.1
  • 49
    • 65749092176 scopus 로고    scopus 로고
    • Intestinal T cells: Facing the mucosal immune dilemma with synergy and diversity
    • F. van Wijk, and H. Cheroutre Intestinal T cells: facing the mucosal immune dilemma with synergy and diversity Semin. Immunol. 21 2009 130 138
    • (2009) Semin. Immunol. , vol.21 , pp. 130-138
    • Van Wijk, F.1    Cheroutre, H.2
  • 50
    • 77952776857 scopus 로고    scopus 로고
    • Immunotherapy can reject intracranial tumor cells without damaging the brain despite sharing the target antigen
    • B.W. Bridle Immunotherapy can reject intracranial tumor cells without damaging the brain despite sharing the target antigen J. Immunol. 184 2010 4269 4275
    • (2010) J. Immunol. , vol.184 , pp. 4269-4275
    • Bridle, B.W.1
  • 51
    • 58849109529 scopus 로고    scopus 로고
    • Immune regulation in the brain: Lessons from autoimmunity, implications for brain tumor therapy
    • F. Ali-Osman, Humana
    • L.A. Lampson Immune regulation in the brain: lessons from autoimmunity, implications for brain tumor therapy F. Ali-Osman, Brain Tumors 2005 Humana 175 205
    • (2005) Brain Tumors , pp. 175-205
    • Lampson, L.A.1
  • 52
    • 58149177780 scopus 로고    scopus 로고
    • TLR ligands in the local treatment of established intracerebral murine gliomas
    • O.M. Grauer TLR ligands in the local treatment of established intracerebral murine gliomas J. Immunol. 181 2008 6720 6729
    • (2008) J. Immunol. , vol.181 , pp. 6720-6729
    • Grauer, O.M.1
  • 53
    • 80055077718 scopus 로고    scopus 로고
    • Possible origin of CSF antibodies induced by intrathecal immunization and prophylactic effects against intracerebral rabies virus infection
    • K. Aoshima Possible origin of CSF antibodies induced by intrathecal immunization and prophylactic effects against intracerebral rabies virus infection J. Vet. Med. Sci. 73 2011 1303 1308
    • (2011) J. Vet. Med. Sci. , vol.73 , pp. 1303-1308
    • Aoshima, K.1
  • 54
    • 0022576609 scopus 로고
    • Monoclonal antibody analysis of MHC expression in human brain biopsies: Tissue ranging from 'histologically normal' to that showing different levels of glial tumor involvement
    • L.A. Lampson, and W.F. Hickey Monoclonal antibody analysis of MHC expression in human brain biopsies: tissue ranging from 'histologically normal' to that showing different levels of glial tumor involvement J. Immunol. 136 1986 4054 4062 (Pubitemid 16123050)
    • (1986) Journal of Immunology , vol.136 , Issue.11 , pp. 4054-4062
    • Lampson, L.A.1    Hickey, W.F.2
  • 55
    • 78650988917 scopus 로고    scopus 로고
    • 1 T cells that are effective in adoptive therapy for large and established tumors
    • 1 T cells that are effective in adoptive therapy for large and established tumors Blood 117 2011 118 127
    • (2011) Blood , vol.117 , pp. 118-127
    • Goldstein, M.J.1
  • 56
    • 0025886953 scopus 로고
    • Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells
    • P.D. Greenberg Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells Adv. Immunol. 49 1991 281 355
    • (1991) Adv. Immunol. , vol.49 , pp. 281-355
    • Greenberg, P.D.1
  • 57
    • 0042063651 scopus 로고    scopus 로고
    • Robust ability of IFN-γ to upregulate class II MHC antigen expression in tumor bearing rat brains
    • DOI 10.1023/A:1024973506989
    • T. Dutta Robust ability of IFN-gamma to upregulate class II MHC antigen expression in tumor bearing rat brains J. Neuro-oncology 64 2003 31 44 (Pubitemid 36992458)
    • (2003) Journal of Neuro-Oncology , vol.64 , Issue.1-2 , pp. 31-44
    • Dutta, T.1    Spence, A.2    Lampson, L.A.3
  • 58
    • 79955658799 scopus 로고    scopus 로고
    • Resistance to HER2 inhibitors: Is addition better than substitution? Rationale for the hypothetical concept of drug sedimentation
    • M. Campone Resistance to HER2 inhibitors: is addition better than substitution? Rationale for the hypothetical concept of drug sedimentation Crit. Rev. Oncol./Hematol. 78 2011 195 205
    • (2011) Crit. Rev. Oncol./Hematol. , vol.78 , pp. 195-205
    • Campone, M.1
  • 59
    • 75749146563 scopus 로고    scopus 로고
    • Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors
    • J. Zhang Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors Nature 463 2010 501 506
    • (2010) Nature , vol.463 , pp. 501-506
    • Zhang, J.1
  • 60
    • 0027392648 scopus 로고
    • Exploiting the lacZ reporter gene for quantitative analysis of disseminated tumor growth within the brain: Use of the lacZ gene product as a tumor antigen, for evaluation of antigenic modulation, and to facilitate image analysis of tumor growth in situ
    • L.A. Lampson Exploiting the lacZ reporter gene for quantitative analysis of disseminated tumor growth within the brain: use of the lacZ gene product as a tumor antigen, for evaluation of antigenic modulation, and to facilitate image analysis of tumor growth in situ Cancer Res. 53 1993 176 182 (Pubitemid 23019395)
    • (1993) Cancer Research , vol.53 , Issue.1 , pp. 176-182
    • Lampson, L.A.1    Lampson, M.A.2    Dunne, A.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.