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Volumn 12, Issue 4, 2013, Pages 324-

Moving towards early clinical trials for amyloid-targeted therapy in Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AVAGACESTAT; BAPINEUZUMAB; MEMANTINE; SEMAGACESTAT; SOLANEZUMAB;

EID: 84875697254     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd3842-c1     Document Type: Letter
Times cited : (62)

References (10)
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  • 3
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    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy, J. & Selkoe, D. J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356 (2002).
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    • Hardy, J.1    Selkoe, D.J.2
  • 4
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    • Testing the right target and right drug at the right stage
    • Sperling, R. A., Jack, C. R. & Aisen, P. S. Testing the right target and right drug at the right stage. Sci. Transl. Med. 3, 111cm33 (2011).
    • (2011) Sci. Transl. Med. , vol.3
    • Sperling, R.A.1    Jack, C.R.2    Aisen, P.S.3
  • 5
    • 84864471159 scopus 로고    scopus 로고
    • A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
    • Jonsson, T. et al. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature 488, 96-99 (2012).
    • (2012) Nature , vol.488 , pp. 96-99
    • Jonsson, T.1
  • 6
    • 79956098248 scopus 로고    scopus 로고
    • Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • Sperling, R. A. et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 7, 280-292 (2011).
    • (2011) Alzheimers Dement. , vol.7 , pp. 280-292
    • Sperling, R.A.1
  • 7
    • 77954239263 scopus 로고    scopus 로고
    • Biomarkers for Alzheimer's disease: Academic, industry and regulatory perspectives
    • Hampel, H. et al. Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives. Nature Rev. Drug Discov. 9, 560-574 (2010).
    • (2010) Nature Rev. Drug Discov. , vol.9 , pp. 560-574
    • Hampel, H.1
  • 8
    • 84865529158 scopus 로고    scopus 로고
    • Clinical and biomarker changes in dominantly inherited Alzheimer's disease; The Dominantly Inherited Alzheimer Network
    • Bateman, R. J. et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease; the Dominantly Inherited Alzheimer Network. N. Engl. J. Med. 367, 795-804 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , pp. 795-804
    • Bateman, R.J.1
  • 9
    • 77954033257 scopus 로고    scopus 로고
    • Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
    • Rowe, C. C. et al. Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging. Neurobiol. Aging. 31, 1275-1283 (2010).
    • (2010) Neurobiol. Aging. , vol.31 , pp. 1275-1283
    • Rowe, C.C.1
  • 10
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    • Down's syndrome and Alzheimer's disease: Towards secondary prevention
    • Ness, S. et al. Down's syndrome and Alzheimer's disease: towards secondary prevention. Nature Rev. Drug Discov. 11, 655-656 (2012).
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    • Ness, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.