Sphincter training or anal injections of dextranomer for treatment of anal incontinence: A randomized trial

Scandinavian Journal of Gastroenterology

Volumn 48, Issue 3, 2013, Pages 302-310

  Dehli, Trond ^a,b   Stordahl, Arvid ^c   Vatten, Lars J ^d   Romundstad, Pål R ^d   Mevik, Kjersti ^e   Sahlin, Ylva ^f   Lindsetmo, Rolv O ^a,b   Vonen, Barthold ^a,b,e  

^a UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^b UNIVERSITY OF TROMSØ   (Norway)

^c Østfold Hospital   (Norway)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^e NORDLAND HOSPITAL   (Norway)

^f Innlandet Hospital   (Norway)

Author keywords

Biofeedback; Bulking agent; Controlled trial; Fecal incontinence; Injectable; Sphincter training

Indexed keywords

DEXTRANOMER; HYALURONIC ACID;

ADULT; ANUS SPHINCTER; ARTICLE; CONTINENCE; CONTROLLED STUDY; FECES INCONTINENCE; FEEDBACK SYSTEM; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MUSCLE TRAINING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SPHINCTER TRAINING; TREATMENT OUTCOME;

ANAL CANAL; BIOFEEDBACK, PSYCHOLOGY; CONFIDENCE INTERVALS; DEXTRANS; ELECTRIC STIMULATION THERAPY; FECAL INCONTINENCE; FEMALE; HEALTH STATUS; HUMANS; MALE; MANOMETRY; MIDDLE AGED; QUALITY OF LIFE; QUESTIONNAIRES; SEVERITY OF ILLNESS INDEX; SINGLE-BLIND METHOD;

EID: 84875695013     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2012.758770     Document Type: Article

References (25)

1. Perry S, Shaw C, McGrother C, Matthews RJ, Assassa RP, Dallosso H, et al. Prevalence of faecal incontinence in adults aged 40 years or more living in the community. Gut 2002;50: 480-4.
2. Whitehead WE, Borrud L, Goode PS, Meikle S, Mueller ER, Tuteja A, et al. Fecal incontinence in US adults: epidemiology and risk factors. Gastroenterology 2009;137:512-17.
3. Sailer M, Bussen D, Debus ES, Fuchs KH, Thiede A. Quality of life in patients with benign anorectal disorders. Br J Surg 1998;85:1716-19.
4. Norderval S, Nsubuga D, Bjelke C, Frasunek J, Myklebust I, Vonen B. Anal incontinence after obstetric sphincter tears: incidence in a Norwegian county. Acta Obstet Gynecol Scand 2004;83:989-94.
5. Madoff RD, Parker SC, Varma MG, Lowry AC. Faecal incontinence in adults. Lancet 2004;364:621-32.
6. Engel BT, Nikoomanesh P, Schuster MM. Operant conditioning of rectosphincteric responses in the treatment of fecal incontinence. N Engl J Med 1974;290:646-9.
7. Norton C, Cody JD, Hosker G. Biofeedback and/or sphincter exercises for the treatment of faecal incontinence in adults. Cochrane Database Syst Rev 2006;3:CD002111.
8. Heymen S, Scarlett Y, Jones K, Ringel Y, Drossman D, Whitehead WE. Randomized controlled trial shows biofeedback to be superior to pelvic floor exercises for fecal incontinence. Dis Colon Rectum 2009;52:1730-7.
9. Schwandner T, Konig IR, Heimerl T, Kierer W, Roblick M, Bouchard R, et al. Triple target treatment (3T) is more effective than biofeedback alone for anal incontinence: the 3T-AI study. Dis Colon Rectum 2010;53:1007-16.
10. Luo C, Samaranayake CB, Plank LD, Bissett IP. Systematic review on the efficacy and safety of injectable bulking agents for passive faecal incontinence. Colorectal Dis 2010; 12:296-303.
11. Siproudhis L, Morcet J, Laine F. Elastomer implants in faecal incontinence: a blind, randomized placebo-controlled study. Aliment Pharmacol Ther 2007;25:1125-32.
12. Maeda Y, Laurberg S, Norton C. Perianal injectable bulking agents as treatment for faecal incontinence in adults. Cochrane Database Syst Rev 2010:CD007959.
13. Graf W, Mellgren A, Matzel KE, Hull T, Johansson C, Bernstein M. Efficacy of dextranomer in stabilised hyaluronic acid for treatment of faecal incontinence: a randomised, sham-controlled trial. Lancet 2011;377:997-1003.
14. Vaizey CJ, Carapeti E, Cahill JA, Kamm M.A. Prospective comparison of faecal incontinence grading systems. Gut 1999;44:77-80.
15. Dehli T, Martinussen M, Mevik K, Stordahl A, Sahlin Y, Lindsetmo RO, et al. Translation and validation of the Norwegian version of the fecal incontinence quality-of-life scale. Scand J Surg 2011;100:190-5.
16. Norton C, Chelvanayagam S, Wilson-Barnett J, Redfern S, Kamm M.A. Randomized controlled trial of biofeed-back for fecal incontinence. Gastroenterology 2003;125: 1320-9.
17. Dehli T, Lindsetmo RO, Mevik K, Vonen B. Anal incontinence-assessment of a new treatment. Tidsskr Nor Laege-foren 2007;127:2934-6.
18. Rockwood TH, Church JM, Fleshman JW, Kane RL, Mavrantonis C, Thorson AG, et al. Fecal incontinence quality of life scale: quality of life instrument for patients with fecal incontinence. Dis Colon Rectum 2000;43:9-16.
19. The EuroQoL Group. EQ-5D: A Standardised Instrument for Use as a Measurement of Health Outcome. 2011. http://www.euroqol.org/.
20. Dobben AC, Terra MP, Berghmans B, Deutekom M, Boeckxstaens GE, Janssen LW, et al. Functional changes after physiotherapy in fecal incontinence. Int J Colorectal Dis 2006;21:515-21.
21. Norderval S, Dehli T, Vonen B. Three-dimensional endoanal ultrasonography: intraobserver and interobserver agreement using scoring systems for classification of anal sphincter defects. Ultrasound Obstet Gynecol 2009;33:337-43.
22. Tjandra JJ, Lim JF, Hiscock R, Rajendra P. Injectable sili-cone biomaterial for fecal incontinence caused by internal anal sphincter dysfunction is effective. Dis Colon Rectum 2004;47:2138-46.
23. Altmann DG. Clinical trials. In Altmann DG, editor. Practical statistics for medical research. London: Chapmann & Hall; 1991. pp 440-76.
24. Brown SR, Wadhawan H, Nelson RL. Surgery for faecal incontinence in adults. Cochrane Database Syst Rev 2010: CD001757.
25. Rao SS. Diagnosis and management of fecal incontinence. American College of Gastroenterology Practice Parameters Committee. Am J Gastroenterol 2004;99:1585-604.