A comparative study of the efficacy of 4% hydroquinone vs 0.75% Kojic acid cream in the treatment of facial melasma

Indian Journal of Dermatology

Volumn 58, Issue 2, 2013, Pages 157-

  Monteiro, Rochelle C ^a   Kishore, Nanda ^a   Bhat, Ramesh M ^a   Sukumar, D ^a   Martis, Jacintha ^a   Ganesh, Kamath ^a  

^a FATHER MULLER MEDICAL COLLEGE   (India)

Author keywords

0.75 Kojic Acid cream; 4 Hydroquinone cream; Melasma

Indexed keywords

ASCORBIC ACID; HYDROQUINONE; KOJIC ACID; KOJIC ACID PLUS VITAMIN C; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHLOASMA; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFICACY; EVENING DOSAGE; FACE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTPATIENT CARE; TREATMENT RESPONSE;

EID: 84875692994     PISSN: 00195154     EISSN: 19983611     Source Type: Journal    
DOI: 10.4103/0019-5154.108070     Document Type: Article

References (13)

1. Guevara IL, Pandya AG. Safety and efficacy of 4% hydroquinone combined with 10% glycolic acid, antioxidants, and sunscreen in the treatment of Melasma. Int J Dermatol 2003;42:966-72.
2. Thappa DM. Melasma (Chloasma): A review with current treatment options. Indian J Dermatol 2004;49:165-76.
3. Torok HM. A comprehensive review of the long term and short term treatment of Melasma with a triple combination cream. Am J Clin Dermatol 2006;7:223-30.
4. Bandyopadhyay D. Topical treatment of melasma. Indian J Dermatol 2009;54:303-9.
5. Stratigos AJ, Katsambas AD. Optimal management of recalcitrant disorders of hyperpigmentation in dark skinned patients. Am J Clin Dermatol 2004;5:161-8.
6. Perez-Bernal A, Munol-Perez MA, Camacho F. Management of facial hyperpigmentation. Am J Clin Dermatol 2000;1:261-8.
7. Pandhi R, Kaur I, Handa S. Comparative evaluation of topical preparations in treatment of melasma. Indian J Dermatol 2002;47:76-9.
8. Ennes S, Paschoalick R, Alchorne MMDA. A double-blind, comparative, placebo-controlled study of the efficacy and tolerability of 4% hydroquinone as a depigmenting agent in melasma. J Dermatolog Treat 2000;11:173-9.
9. Haddad AL, Matos LF, Brunstein F, Ferreira LM, Silva A, Costa D, et al. A clinical, prospective, randomized, double blind trial comparing skin whitening complex with hydroquinone vs. placebo in the treatment of melasma. Int J Dermatol 2003;42:153-6.
10. Amer M, Metwalli M. Topical hydroquinone in the treatment of some hyperpigmentary disorders. Int J Dermatol 1998;37:449-50.
11. Lim JT. Treatment of Melasma using Kojic Acid in a gel containing Hydroquinone and Glycolic Acid. Dermatol Surg 1999;25:282-4
12. Cotellessa C, Peris K, Onorati MT, Fargnoli MC, Chimenti S. The use of chemical peelings in the treatment of different cutaneous hyperpigmentations. Dermatol Surg 1999;25:450-4.
13. Garcia A, Fulton JE Jr. The combination of glycolic acid and hydroquinone or Kojic acid for the treatment of Melasma and related conditions. Dermatol Surg 1996;22:443-7.