High EGFR copy number predicts benefits from tyrosine kinase inhibitor treatment for non-small cell lung cancer patients with wild-type EGFR

Journal of Translational Medicine

Volumn 11, Issue 1, 2013, Pages

  Wang, Fang ^a   Fu, Sha ^a   Shao, Qiong ^a   Zhou, Yan Bin ^b   Zhang, Xiao ^a   Zhang, Xu ^a   Xue, Cong ^a   Lin, Jian Guang ^c   Huang, Li Xia ^b   Zhang, Li ^a   Zhang, Wei Min ^c   Shao, Jian Yong ^a,b  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

Author keywords

Copy number; EGFR; Lung cancer; Mutation

Indexed keywords

BIOLOGICAL MARKER; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; EGFR PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; EPIDERMAL GROWTH FACTOR RECEPTOR GENE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DOSAGE; GENE MUTATION; GENETIC SCREENING; HUMAN; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PREDICTIVE VALUE; PROGRESSION FREE SURVIVAL; SURVIVAL RATE; SURVIVAL TIME; WILD TYPE; ANTAGONISTS AND INHIBITORS; CARCINOMA, NON-SMALL-CELL LUNG; DISEASE FREE SURVIVAL; GENETICS; KAPLAN MEIER METHOD; LUNG NEOPLASMS; MUTATION; PATHOLOGY; PROPORTIONAL HAZARDS MODEL; SURVIVAL; TREATMENT OUTCOME;

CARCINOMA, NON-SMALL-CELL LUNG; DISEASE-FREE SURVIVAL; GENE DOSAGE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MUTATION; PROPORTIONAL HAZARDS MODELS; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84875689573     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-11-90     Document Type: Article

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