Evaluating the use of Apo-neocarzinostatin as a cell penetrating protein

Protein Engineering, Design and Selection

Volumn 26, Issue 4, 2013, Pages 277-281

  Moody, Paul ^a,c   Burlina, Fabienne ^b   Martin, Stephen R ^c   Morgan, Rachel E ^a   Offer, John ^c   Smith, Mark E B ^a   Molloy, Justin E ^c   Caddick, Stephen ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b SORBONNE UNIVERSITÉ   (France)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

cell internalisation; cell penetrating protein; drug delivery; Neocarzinostatin; protein drug conjugate

Indexed keywords

CELL TARGETING; COMPLEMENTARITY-DETERMINING REGIONS; INTRACELLULAR DELIVERY; MAMMALIAN CELLS; NEOCARZINOSTATIN; PROTEIN-DRUG CONJUGATE; PROTEIN-LIGAND COMPLEXES; SMALL-MOLECULE DRUGS;

COMPLEXATION; CYTOLOGY; DRUG DELIVERY; FLUORESCENCE MICROSCOPY; MASS SPECTROMETRY; PROTEINS;

SCAFFOLDS (BIOLOGY);

APOZINOSTATIN;

ARTICLE; FEMALE; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; HUMAN CELL; INTERNALIZATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CELL-PENETRATING PEPTIDES; DNA DAMAGE; HELA CELLS; HUMANS; KINETICS; LIGANDS; MICROSCOPY, FLUORESCENCE; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; ZINOSTATIN;

MAMMALIA;

EID: 84875660285     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzs104     Document Type: Article

References (25)

1. Burlina,F., Sagan,S., Bolbach,G. and Chassaing,G. (2005) Angew. Chem. Int. Ed. Engl., 44, 4244-4247.
2. Burlina,F., Sagan,S., Bolbach,G. and Chassaing,G. (2006) Nat. Protoc., 1, 200-205.
3. Caddick,S., Muskett,F.W., Stoneman,R.G. and Woolfson,D.N. (2006) J. Am. Chem. Soc., 128, 4204-4205.
4. D'Andrea,A.D. and Haseltine,W.A. (1978) Proc. Natl Acad. Sci. USA, 75, 3608-3612.
5. Hensens,O.D., Chin,D.H., Stassinopoulos,A., Zink,D.L., Kappen,L.S. and Goldberg,I.H. (1994) Proc. Natl Acad. Sci. USA, 91, 4534-4538.
6. Jayachithra,K., Kumar,T.K.S., Lu,T.J., Yu,C. and Chin,D.H. (2005) Biophys. J., 88, 4252-4261.
7. Kappen,L.S., Napier,M.A. and Goldberg,I.H. (1980) Proc. Natl Acad. Sci. USA, 77, 1970-1974.
8. Kim,K.H., Kwon,B.M., Myers,A.G. and Rees,D.C. (1993) Science, 262, 1042-1046.
9. Konno,T. (1992) Eur. J. Cancer, 28, 403-409.
10. Konno,T., Kai,Y., Yamashita,R., Nagamitsu,A. and Kimura,M. (1994) Acta. Oncol., 33, 133-137.
11. Kuromizu,K., Tsunasawa,S., Maeda,H., Abe,O. and Sakiyama,F. (1986) Arch. Biochem. Biophys., 246, 199-205.
12. Maeda,H., Takeshita,J. and Kanamaru,R. (1979) Int. J. Pept. Protein Res., 14, 81-87.
13. Meienhofer,J., Maeda,H., Glaser,C.B., Czombos,J. and Kuromizu,K. (1972) Science, 178, 875-876.
14. Napier,M.A., Holmquist,B., Strydom,D.J. and Goldberg,I.H. (1979) Biochem. Biophys. Res. Commun., 89, 635-642.
15. Nicaise,M., Valerio-Lepiniec,M., Minard,P. and Desmadril,M. (2004) Protein Sci., 13, 1882-1891.
16. Oda,T. and Maeda,H. (1987) Cancer Res., 47, 3206-3211.
17. Povirk,L.F. and Goldberg,I.H. (1980) Biochemistry, 19, 4773-4780.
18. Schaus,S.E., Cavalieri,D. and Myers,A.G. (2001) Proc. Natl Acad. Sci. USA, 98, 11075-11080.
19. Sudhahar,C.G. and Chin,D.H. (2006) Bioorg. Med. Chem., 14, 3543-3552.
20. Takashima,H., Yoshida,T., Ishino,T., Hasuda,K., Ohkubo,T. and Kobayashi,Y. (2005) J. Biol. Chem., 280, 11340-11346.
21. Takeshita,J., Maeda,H. and Koike,K. (1980) J. Biochem., 88, 1071-1080.
22. Teplyakov,A., Obmolova,G., Wilson,K. and Kuromizu,K. (1993) Eur. J. Biochem., 213, 737-741.
23. Urbaniak,M.D., Muskett,F.W., Finucane,M.D., Caddick,S. and Woolfson,D.N. (2002) Biochemistry, 41, 11731-11739.
24. Vives,E., Brodin,P. and Lebleu,B. (1997) J. Biol. Chem., 272, 16010-16017.
25. Zorko,M. and Langel,U. (2005) Adv. Drug Deliv. Rev., 57, 529-545.