메뉴 건너뛰기




Volumn 98, Issue 4, 2013, Pages 487-489

Multiple myeloma: So much progress, but so many unsolved questions

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; DEXAMETHASONE; LENALIDOMIDE; MELPHALAN; THALIDOMIDE;

EID: 84875654640     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2013.083592     Document Type: Editorial
Times cited : (12)

References (23)
  • 1
    • 79955821742 scopus 로고    scopus 로고
    • Current trends in autologous stem-cell transplantation for myeloma in the era of novel therapies
    • Moreau P, Avet-Loiseau H, Harousseau JL, Attal M. Current trends in autologous stem-cell transplantation for myeloma in the era of novel therapies. J Clin Oncol. 2011;29(14):1898-906.
    • (2011) J Clin Oncol. , vol.29 , Issue.14 , pp. 1898-1906
    • Moreau, P.1    Avet-Loiseau, H.2    Harousseau, J.L.3    Attal, M.4
  • 2
    • 79959398524 scopus 로고    scopus 로고
    • International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation
    • Cavo M, Rajkumar SV, Palumbo A, Moreau P, Orlowski R, Bladé J, et al. International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation. Blood. 2011;117(23):6063-73.
    • (2011) Blood. , vol.117 , Issue.23 , pp. 6063-6073
    • Cavo, M.1    Rajkumar, S.V.2    Palumbo, A.3    Moreau, P.4    Orlowski, R.5    Bladé, J.6
  • 3
    • 80052345517 scopus 로고    scopus 로고
    • Can multiple myeloma become a curable disease?
    • San-Miguel JF, Mateos MV. Can multiple myeloma become a curable disease? Haematologica. 2011;96(9):1246-8.
    • (2011) Haematologica. , vol.96 , Issue.9 , pp. 1246-1248
    • San-Miguel, J.F.1    Mateos, M.V.2
  • 4
    • 73249146496 scopus 로고    scopus 로고
    • Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: An open-label randomised controlled trial
    • Rajkumar SV, Jacobus S, Callander NS, Fonseca R, Vesole DH, Williams ME, et al. Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial. Lancet Oncol. 2010;11(1):29-37.
    • (2010) Lancet Oncol. , vol.11 , Issue.1 , pp. 29-37
    • Rajkumar, S.V.1    Jacobus, S.2    Callander, N.S.3    Fonseca, R.4    Vesole, D.H.5    Williams, M.E.6
  • 5
    • 77954618168 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
    • Richardson PG, Weller E, Lonial S, Jakubowiak AJ, Jagannath S, Raje NS, et al. Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma. Blood. 2010;116(5):679-86.
    • (2010) Blood. , vol.116 , Issue.5 , pp. 679-686
    • Richardson, P.G.1    Weller, E.2    Lonial, S.3    Jakubowiak, A.J.4    Jagannath, S.5    Raje, N.S.6
  • 6
    • 84855232180 scopus 로고    scopus 로고
    • Melphalan/prednisone/lenalidomide (MPR) versus high-dose melphalan and autologous transplantation (MEL200) in newly diagnosed multiple myeloma (MM) patients: A phase III trial
    • (Abstract 8020)
    • Boccadoro M, Cavallo F, Nagler A, Ben Yehuda D, Omedè P, Cavalli M, et al. Melphalan/prednisone/lenalidomide (MPR) versus high-dose melphalan and autologous transplantation (MEL200) in newly diagnosed multiple myeloma (MM) patients: a phase III trial. J Clin Oncol. 2011;29(15 Suppl):(Abstract 8020).
    • (2011) J Clin Oncol. , vol.29 , Issue.15 SUPPL.
    • Boccadoro, M.1    Cavallo, F.2    Nagler, A.3    Ben Yehuda, D.4    Omedè, P.5    Cavalli, M.6
  • 7
    • 84860219443 scopus 로고    scopus 로고
    • The genetic architecture of multiple myeloma
    • Morgan GJ, Walker BA, Davies FE. The genetic architecture of multiple myeloma. Nat Rev Cancer. 2012;12(5):335-48.
    • (2012) Nat Rev Cancer. , vol.12 , Issue.5 , pp. 335-348
    • Morgan, G.J.1    Walker, B.A.2    Davies, F.E.3
  • 8
    • 77953632707 scopus 로고    scopus 로고
    • Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial 2006-66 with VRD maintenance
    • Nair B, van Rhee F, Shaughnessy JD Jr, Anaissie E, Szymonifka J, Hoering A, et al. Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial 2006-66 with VRD maintenance. Blood. 2010;115(21);4168-73.
    • (2010) Blood. , vol.115 , Issue.21 , pp. 4168-4173
    • Nair, B.1    van Rhee, F.2    Shaughnessy Jr., J.D.3    Anaissie, E.4    Szymonifka, J.5    Hoering, A.6
  • 9
    • 72949085546 scopus 로고    scopus 로고
    • Management of newly diagnosed symptomatic multiple myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines
    • Kumar SK, Mikhael JR, Buadi FK, Dingli D, Dispenzieri A, Fonseca R, et al. Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines. Mayo Clin Proceed. 2009;84(12):1095-110.
    • (2009) Mayo Clin Proceed. , vol.84 , Issue.12 , pp. 1095-1110
    • Kumar, S.K.1    Mikhael, J.R.2    Buadi, F.K.3    Dingli, D.4    Dispenzieri, A.5    Fonseca, R.6
  • 10
    • 79955977910 scopus 로고    scopus 로고
    • Consensus recommendations for the uniform reporting of clinical trials: Report of the International Myeloma Workshop Consensus Panel 1
    • Rajkumar SV, Harousseau JL, Durie B, Anderson KC, Dimopoulos M, Kyle R, et al. Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1. Blood. 2011(18);117:4691-5.
    • (2011) Blood. , vol.117 , Issue.18 , pp. 4691-4695
    • Rajkumar, S.V.1    Harousseau, J.L.2    Durie, B.3    Anderson, K.C.4    Dimopoulos, M.5    Kyle, R.6
  • 11
    • 77951625298 scopus 로고    scopus 로고
    • Major tumor shrinking and persistent molecular remissions after consolidation with bortezomib, thalidomide, and dexamethasone in patients with autografted myeloma
    • Ladetto M, Pagliano G, Ferrero S, Cavallo F, Drandi D, Santo L, et al. Major tumor shrinking and persistent molecular remissions after consolidation with bortezomib, thalidomide, and dexamethasone in patients with autografted myeloma. J Clin Oncol. 2010;28(12):2077-84.
    • (2010) J Clin Oncol. , vol.28 , Issue.12 , pp. 2077-2084
    • Ladetto, M.1    Pagliano, G.2    Ferrero, S.3    Cavallo, F.4    Drandi, D.5    Santo, L.6
  • 12
    • 79961078524 scopus 로고    scopus 로고
    • Molecular remission after bortezomib-thalidomide-dexamethasone compared with thalidomide-dexamethasone as consolidation therapy following double autologous transplantation for multiple myeloma: Results of a qualitative and quantitative analysis
    • Terragna C, Zamagni E, Petrucci MT, Durante S, Patriarca F, Narni F, et al. Molecular remission after bortezomib-thalidomide-dexamethasone compared with thalidomide-dexamethasone as consolidation therapy following double autologous transplantation for multiple myeloma: results of a qualitative and quantitative analysis. Blood. 2010;116 (21):861.
    • (2010) Blood. , vol.116 , Issue.21 , pp. 861
    • Terragna, C.1    Zamagni, E.2    Petrucci, M.T.3    Durante, S.4    Patriarca, F.5    Narni, F.6
  • 13
    • 73349127140 scopus 로고    scopus 로고
    • The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic multiple myeloma patients
    • Paiva B, Vidriales MB, Mateo G, Pérez JJ, Montalbán MA, Sureda A, et al. The persistence of immunophenotypically normal residual bone marrow plasma cells at diagnosis identifies a good prognostic subgroup of symptomatic multiple myeloma patients. Blood. 2009;114(20):4369-72.
    • (2009) Blood. , vol.114 , Issue.20 , pp. 4369-4372
    • Paiva, B.1    Vidriales, M.B.2    Mateo, G.3    Pérez, J.J.4    Montalbán, M.A.5    Sureda, A.6
  • 14
    • 84875679894 scopus 로고    scopus 로고
    • Sequential immunomodulatory drug and proteasome inhibitor therapy improves response rates in newly diagnosed multiple myeloma: Preliminary results from the Myeloma XI trial
    • Abstract 335
    • Pawlyn C, Davies FE, Gregory WM, Szubert AJ, Bell SE, Ouzman J, et al. Sequential immunomodulatory drug and proteasome inhibitor therapy improves response rates in newly diagnosed multiple myeloma: preliminary results from the Myeloma XI trial. Blood. 2010;120:Abstract 335.
    • (2010) Blood. , vol.120
    • Pawlyn, C.1    Davies, F.E.2    Gregory, W.M.3    Szubert, A.J.4    Bell, S.E.5    Ouzman, J.6
  • 15
    • 54249092519 scopus 로고    scopus 로고
    • Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: A study of the Intergroupe Francophone du Myélome
    • Decaux O, Lodé L, Magrangeas F, Charbonnel C, Gouraud W, Jézéquel P, et al. Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: a study of the Intergroupe Francophone du Myélome. J Clin Oncol. 2008;26(29):4798-805.
    • (2008) J Clin Oncol. , vol.26 , Issue.29 , pp. 4798-4805
    • Decaux, O.1    Lodé, L.2    Magrangeas, F.3    Charbonnel, C.4    Gouraud, W.5    Jézéquel, P.6
  • 16
    • 77957733923 scopus 로고    scopus 로고
    • Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients
    • Broyl A, Hose D, Lokhorst H, de Knegt Y, Peeters J, Jauch A, et al. Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients. Blood. 2010;116(14):2543-53.
    • (2010) Blood. , vol.116 , Issue.14 , pp. 2543-2553
    • Broyl, A.1    Hose, D.2    Lokhorst, H.3    de Knegt, Y.4    Peeters, J.5    Jauch, A.6
  • 17
    • 77949686098 scopus 로고    scopus 로고
    • Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome
    • Dickens NJ, Walker BA, Leone PE, Johnson DC, Brito JL, Zeisig A, et al. Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome. Clin Cancer Res. 2010;16(6):1856-64.
    • (2010) Clin Cancer Res. , vol.16 , Issue.6 , pp. 1856-1864
    • Dickens, N.J.1    Walker, B.A.2    Leone, P.E.3    Johnson, D.C.4    Brito, J.L.5    Zeisig, A.6
  • 18
    • 82955189267 scopus 로고    scopus 로고
    • Prognostic relevance of 18-F FDG PET-CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation
    • Zamagni E, Patriarca F, Nanni C, Zannetti B, Englaro E, Pezzi A, et al. Prognostic relevance of 18-F FDG PET-CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation. Blood. 2011;118(23):5989-95.
    • (2011) Blood. , vol.118 , Issue.23 , pp. 5989-5995
    • Zamagni, E.1    Patriarca, F.2    Nanni, C.3    Zannetti, B.4    Englaro, E.5    Pezzi, A.6
  • 19
    • 84864561961 scopus 로고    scopus 로고
    • Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides
    • Egan JB, Shi CX, Tembe W, Christoforides A, Kurdoglu A, Sinari S, et al. Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides. Blood. 2012;120(5):1060-6.
    • (2012) Blood. , vol.120 , Issue.5 , pp. 1060-1066
    • Egan, J.B.1    Shi, C.X.2    Tembe, W.3    Christoforides, A.4    Kurdoglu, A.5    Sinari, S.6
  • 22
    • 84864544413 scopus 로고    scopus 로고
    • Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma
    • Walker BA, Wardell CP, Melchor L, Hulkki S, Potter NE, Johnson DC, et al. Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma. Blood. 2012;120(5):1077-86.
    • (2012) Blood. , vol.120 , Issue.5 , pp. 1077-1086
    • Walker, B.A.1    Wardell, C.P.2    Melchor, L.3    Hulkki, S.4    Potter, N.E.5    Johnson, D.C.6
  • 23
    • 79960693423 scopus 로고    scopus 로고
    • Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients
    • Magrangeas F, Avet-Loiseau H, Munshi NC, Minvielle S. Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients. Blood. 2011;118(3):675-8.
    • (2011) Blood. , vol.118 , Issue.3 , pp. 675-678
    • Magrangeas, F.1    Avet-Loiseau, H.2    Munshi, N.C.3    Minvielle, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.