A review on the pharmacological and toxicological aspects of Datura stramonium L

Journal of Chinese Integrative Medicine

Volumn 11, Issue 2, 2013, Pages 73-79

  Gaire, Bhakta Prasad ^a   Subedi, Lalita ^b  

^a Kyung Hee University   (South Korea)

^b POKHARA UNIVERSITY   (Nepal)

Author keywords

Datura stramonium; Drug toxicity; Medicine; Pharmacologic actions; Phytotherapy; Review; Traditional

Indexed keywords

ALKALOID; DATURA STRAMONIUM EXTRACT;

ANTICHOLINERGIC EFFECT; ANTIFUNGAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ASTHMA; BOTANY; DATURA STRAMONIUM; DRUG SAFETY; EPILEPSY; HUMAN; INFLAMMATION; INTOXICATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHYTOCHEMISTRY; PHYTOTHERAPY; PHYTOTOXICITY; REVIEW; TOXICITY; ULCER; VEGETATIVE PROPAGATION; WOUND;

EID: 84875622555     PISSN: 16721977     EISSN: None     Source Type: Journal    
DOI: 10.3736/jintegrmed2013016     Document Type: Review

References (41)

1. Fornoni J, Núñez-Farfán J. Evolutionary ecology of Datura stramonium: genetic variation and costs for tolerance to defoliation. Evolution. 2000; 54(3): 789-797.
2. Luna-Cavazos M, Bye R. Phytogeographic analysis of the genus Datura (Solanaceae) in continental Mexico. Rev Mex Biodivers. 2011; 82: 977-988.
3. Berkov S, Zayed R, Doncheva T. Alkaloid patterns in some varieties of Datura stramonium. Fitoterapia. 2006; 77(3): 179-182.
4. Ajungla L, Patil PP, Barmukh RB, Nikam TD. Influence of biotic and abiotic elicitors on accumulation of hyoscyamine and scopolamine in root cultures of Datura metel L. Indian J Biotechnol. 2009; 8(3): 317-322.
5. Dessanges JF. A history of nebulization. J Aerosol Med. 2001; 14(1): 65-71.
6. Diker D, Markovitz D, Rothman M, Sendovski U. Coma as a presenting sign of Datura stramonium seed tea poisoning. Eur J Intern Med. 2007; 18(4): 336-338.
7. Naudé TW, Gerber R, Smith RJ, Botha CJ. Datura contamination of hay as the suspected cause of an extensive outbreak of impaction colic in horses. J S Afr Vet Assoc. 2005; 76(2): 107-112.
8. Norton S. Toxic effects of plants. In: Klaassen CD. Caserett and Doull's toxicology, the basic science of poisons. 7th ed. New York: McGraw Hill. 2008: 1110.
9. Kirtikar KR, Basu BD. Indian medicinal plants. 2nd ed. Volume III. Dehradun: International Book Distributors. 1999: 1783-1787.
10. Gaire BP. Monograph on Datura stramonium. Kaski, Nepal: Pokhara University Press. 2008: 1-114.
11. Khare CP. Indian medicinal plants. Delhi: Rajkamal Electric Press. 2007: 203.
12. Preissel U, Preissel HG. Brugmansia and Datura: Angel's Trumpets and Thorn Apples. New York: Firefly Books. 2002: 106-129.
13. Das S, Kumar P, Basu SP. Review article on phytoconstituents and therapeutic potentials of Datura stramonium Linn. J Drug Deliv Ther. 2012; 2(3): 4-7.
14. Joshi SG. Medicinal plants. New Delhi: Oxford & IBH Publishing Co. Pvt. Ltd. 2000: 370-371.
15. Rajbhandari KR. Ethnobotany of Nepal. Kathmandu: Kishor Offset Press Private Limited. 2001: 142-143.
16. Egharevba RKA, Ikhatua MI. Ethno-medical uses of plants in the treatment of various skin diseases in Ovia North East, Edo State, Nigeria. Res J Agric Biol Sci. 2008; 4(1): 58-64.
17. Gorsi MS, Shahzad R. Medicinal uses of plants with particular reference to the people of Dhirkot, Azad Jammu and Kashmir. Asian J Plant Sci. 2002; 1(3): 222-223.
18. Hussain F, Badshah L, Dastagir G. Folk medicinal uses of some plants of South Waziristan, Pakistan. Pak J Plant Sci. 2006; 12: 27-39.
19. Jakabová S, Vincze L, Farkas A, Kilár F, Boros B, Felinger A. Determination of tropane alkaloids atropine and scopolamine by liquid chromatography-mass spectrometry in plant organs of Datura species. J Chromatogr A. 2012; 1232: 295-301.
20. Berkov S, Pavlov A, Kovatcheva P, Stanimirova P, Philipov S. Alkaloid spectrum in diploid and tetraploid hairy root cultures of Datura stramonium. Z Naturforsch C. 2003; 58(1-2): 42-46.
21. Iranbakhsh A, Oshaghi MA, Majd A. Distribution of atropine and scopolamine in different organs and stages of development in Datura stramonium L. (Solanaceae). Structure and ultrastructure of biosynthesizing cells. Acta Biol Crac Ser Bot. 2006; 48(1): 13-18.
22. Li J, Lin B, Wang G, Gao H, Qin M. Chemical constituents of Datura stramonium seeds. Zhongguo Zhong Yao Za Zhi. 2012; 37(3): 319-322. Chinese with abstract in English.
23. Charpin D, Orehek J, Velardocchio JM. Bronchodilator effects of antiasthmatic cigarette smoke (Datura stramonium). Thorax. 1979; 34(2): 259-261.
24. Pretorius E, Marx J. Datura stramonium in asthma treatment and possible effects on prenatal development. Environ Toxicol Pharmacol. 2006; 21(3): 331-337.
25. Peredery O, Persinger MA. Herbal treatment following postseizure induction in rat by lithium pilocarpine: Scutellaria lateriflora (Skullcap), Gelsemium sempervirens (Gelsemium) and Datura stramonium (Jimson weed) may prevent development of spontaneous seizures. Phytother Res. 2004; 18(9): 700-705.
26. Bania TC, Chu J, Bailes D, O'Neill M. Jimson weed extract as a protective agent in severe organophosphate toxicity. Acad Emerg Med. 2004; 11(4): 335-338.
27. Eftekhar F, Yousefzadi M, Tafakori V. Antimicrobial activity of Datura innoxia and Datura stramonium. Fitoterapia. 2005; 76(1): 118-120.
28. Shagal MH, Modibbo UU, Liman AB. Pharmacological justification for the ethnomedical use of Datura stramonium stem-bark extract in treatment of diseases caused by some pathogenic bacteria. Int Res Pharm Pharmacol. 2012; 2(1): 16-19.
29. Sharma A, Patel VK, Chaturvedi AN. Vibriocidal activity of certain medicinal plants used in Indian folklore medicine by tribals of Mahakoshal region of central India. Indian J Pharmacol. 2009; 41(3): 129-133.
30. Mdee LK, Masoko P, Eloff JN. The activity of extracts of seven common invasive plant species on fungal phytopathogens. S Afr J Bot. 2009; 75(2): 375-379.
31. Sonika G, Manubala R, Deepak J. Comparative studies on anti-inflammatory activity of Coriandrum sativum, Datura stramonium and Azadirachta indica. Asian J Exp Biol Sci. 2010; 1(1): 151-154.
32. Kurnal NA, Çobanoǧlu S, Yalcin C. Acaricidal, repellent and oviposition deterrent activities of Datura stramonium L. against adult Tetranychus urticae (Koch). J Pest Sci. 2010; 83(2): 173-180.
33. Balachandran P, Rajgopal G. Cancer-an Ayurvedic perspective. Pharmacol Res. 2005; 51(1): 19-30.
34. Swathi S, Murugananthan G, Ghosh SK, Pradeep AS. Larvicidal and repellent activities of ethanolic extract of Datura stramonium leaves against mosquitoes. Inter J Pharmacogn Phytochem Res. 2012; 4(1): 25-27.
35. Hirschmann GS, De Arias AR. A survey of medicinal plants of minas gerais, Brazil. J Ethnopharmacol. 1990; 29(2): 159-172.
36. Spina SP, Taddei A. Teenagers with Jimson weed (Datura stramonium) poisoning. CJEM. 2007; 9(6): 467-468.
37. Oberndorfer S, Grisold W, Hinterholzer G, Rosner M. Coma with focal neurological signs caused by Datura stramonium intoxication in a young man. J Neurol Neurosurg Psychiatr. 2002; 73(4): 458-459.
38. Dugan GM, Gumbmann MR, Friedman M. Toxicological evaluation of Jimson weed (Datura stramonium) seed. Food Chem Toxicol. 1989; 27(8): 501-510.
39. Bouzidi A, Mahdeb N, Kara N. Toxicity studies of alkaloids of seeds of Datura stramonium and synthesis alkaloids in male rats. J Med Plants Res. 2011; 5(15): 3421-3431.
40. Kurzbaum A, Simsolo C, Kvasha L, Blum A. Toxic delirium due to Datura stramonium. Isr Med Assoc J. 2001; 3(7): 538-539.
41. Karadaş S, Selvi Y, Şahin M, Selvi F, Öncü R, Özgökçe F. Datura stramonium intoxication: report of a case with psychiatric symptoms. Düşünen Adam: J Psychiatry Neuro Sci. 2011; 24(2): 152-154.