Endosomal trafficking of open Major Histocompatibility Class I conformers-Implications for presentation of endocytosed antigens

Molecular Immunology

Volumn 55, Issue 2, 2013, Pages 149-152

  Mahmutefendić, Hana ^a   Zagorac, Gordana Blagojević ^a   TomaŠ, Maja Ilić ^a   Groettrup, Marcus ^b   Momburg, Frank ^c   Lučin, Pero ^a  

^a UNIVERSITY OF RIJEKA   (Croatia)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Antigen presentation; Cross presentation; Endocytosis; Late endosomes; Major Histocompatibility Class I proteins; Open MHC I conformers

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ACIDITY; CELL MIGRATION; ENDOSOME; PRIORITY JOURNAL; RECYCLING; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; CELL MEMBRANE; CROSS-PRIMING; ENDOCYTOSIS; ENDOSOMES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; MICE; PROTEIN CONFORMATION; PROTEIN TRANSPORT;

EID: 84875619311     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.10.008     Document Type: Review

References (5)

1. Donaldson J.G., Williams D.B. Intracellular assembly and trafficking of MHC class I molecules. Traffic 2009, 10:1745-1752.
2. Huotari J., Helenius A. Endosomal maturation. EMBO Journal 2011, 30:3481-3500.
3. Mahmutefendić H., Blagojević G., Ilić TomaŠ M., Kučić N., Lučin P. Segregation of open Major Histocompatibility class I conformers at the plasma membrane and during endosomal trafficking reveals conformation-based sorting in the endosomal system. International Journal of Biochemistry and Cell Biology 2011, 43:504-515.
4. Tiwari N., Garbi N., Reinheckel T., Moldenhauer G., Hämmerling G.J., Momburg F. A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins. Journal of Immunology 2007, 178:7932-7942.
5. Zagorac G.B., Mahmutefendić H., Ilić TomaŠ M., Kučić N., Le Bouteiller P., Lučin P. Early endosomal rerouting of Major Histocompatibility class I conformers. Journal of Cellular Physiology 2012, 227:2953-2964.