메뉴 건너뛰기




Volumn 14, Issue 4, 2013, Pages 181-190

Sorafenib in combination with transarterial chemoembolization improves the survival of patients with unresectable hepatocellular carcinoma: A propensity score matching study

Author keywords

Hepatocellular carcinoma; Sorafenib; Survival; Transarterial chemoembolization

Indexed keywords

DOXORUBICIN; IODINATED POPPYSEED OIL; MITOMYCIN; SORAFENIB;

EID: 84875609144     PISSN: 17512972     EISSN: 17512980     Source Type: Journal    
DOI: 10.1111/1751-2980.12038     Document Type: Article
Times cited : (87)

References (34)
  • 1
    • 0035467993 scopus 로고    scopus 로고
    • Global cancer statistics in the year 2000
    • Parkin DM. Global cancer statistics in the year 2000. Lancet Oncol 2001; 2: 533-543.
    • (2001) Lancet Oncol , vol.2 , pp. 533-543
    • Parkin, D.M.1
  • 2
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-2576.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 3
    • 17044421361 scopus 로고    scopus 로고
    • Treatment modalities for hepatocellular carcinoma
    • Hung H. Treatment modalities for hepatocellular carcinoma. Curr Cancer Drug Targets 2005; 5: 131-138.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 131-138
    • Hung, H.1
  • 4
    • 0036237822 scopus 로고    scopus 로고
    • Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma
    • Lo CM, Ngan H, Tso WK etal. Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma. Hepatology 2002; 35: 1164-1171.
    • (2002) Hepatology , vol.35 , pp. 1164-1171
    • Lo, C.M.1    Ngan, H.2    Tso, W.K.3
  • 5
    • 0037129704 scopus 로고    scopus 로고
    • Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial
    • Llovet JM, Real MI, Montaña X etal. Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial. Lancet 2002; 359: 1734-1739.
    • (2002) Lancet , vol.359 , pp. 1734-1739
    • Llovet, J.M.1    Real, M.I.2    Montaña, X.3
  • 6
    • 0037308133 scopus 로고    scopus 로고
    • Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival
    • Llovet JM, Bruix J. Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. Hepatology 2003; 37: 429-442.
    • (2003) Hepatology , vol.37 , pp. 429-442
    • Llovet, J.M.1    Bruix, J.2
  • 7
    • 33746528885 scopus 로고    scopus 로고
    • Prospective cohort study of transarterial chemoembolization for unresectable hepatocellular carcinoma in 8510 patients
    • Takayasu K, Arii S, Ikai I etal. Prospective cohort study of transarterial chemoembolization for unresectable hepatocellular carcinoma in 8510 patients. Gastroenterology 2006; 131: 461-469.
    • (2006) Gastroenterology , vol.131 , pp. 461-469
    • Takayasu, K.1    Arii, S.2    Ikai, I.3
  • 8
    • 77749298647 scopus 로고    scopus 로고
    • Overall survival after transarterial lipiodol infusion chemotherapy with or without embolization for unresectable hepatocellular carcinoma: propensity score analysis
    • Takayasu K, Arii S, Ikai I etal. Overall survival after transarterial lipiodol infusion chemotherapy with or without embolization for unresectable hepatocellular carcinoma: propensity score analysis. AJR Am J Roentgenol 2010; 194: 830-837.
    • (2010) AJR Am J Roentgenol , vol.194 , pp. 830-837
    • Takayasu, K.1    Arii, S.2    Ikai, I.3
  • 9
    • 79951556637 scopus 로고    scopus 로고
    • Transarterial chemoembolization for unresectable hepatocellular carcinoma with portal vein tumor thrombosis: a prospective comparative study
    • Luo J, Guo RP, Lai EC etal. Transarterial chemoembolization for unresectable hepatocellular carcinoma with portal vein tumor thrombosis: a prospective comparative study. Ann Surg Oncol 2011; 18: 413-420.
    • (2011) Ann Surg Oncol , vol.18 , pp. 413-420
    • Luo, J.1    Guo, R.P.2    Lai, E.C.3
  • 10
    • 79952341136 scopus 로고    scopus 로고
    • Transarterial chemoembolization can be safely performed in patients with hepatocellular carcinoma invading the main portal vein and may improve the overall survival
    • Chung GE, Lee JH, Kim HY etal. Transarterial chemoembolization can be safely performed in patients with hepatocellular carcinoma invading the main portal vein and may improve the overall survival. Radiology 2011; 258: 627-634.
    • (2011) Radiology , vol.258 , pp. 627-634
    • Chung, G.E.1    Lee, J.H.2    Kim, H.Y.3
  • 11
    • 71849111321 scopus 로고    scopus 로고
    • Transarterial therapies in HCC: does embolization increase survival?
    • Forner A, Trinchet JC. Transarterial therapies in HCC: does embolization increase survival? J Hepatol 2009; 51: 981-983.
    • (2009) J Hepatol , vol.51 , pp. 981-983
    • Forner, A.1    Trinchet, J.C.2
  • 12
    • 41949113329 scopus 로고    scopus 로고
    • Transcatheter arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC): the role of angiogenesis and invasiveness
    • Sergio A, Cristofori C, Cardin R etal. Transcatheter arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC): the role of angiogenesis and invasiveness. Am J Gastroenterol 2008; 103: 914-921.
    • (2008) Am J Gastroenterol , vol.103 , pp. 914-921
    • Sergio, A.1    Cristofori, C.2    Cardin, R.3
  • 13
    • 33745455903 scopus 로고    scopus 로고
    • Quantitative analysis using ELISA of vascular endothelial growth factor and basic fibroblast growth factor in human colorectal cancer, liver metastasis of colorectal cancer and hepatocellular carcinoma
    • Mathonnet M, Descottes B, Valleix D, Labrousse F, Truffinet V, Denizot Y. Quantitative analysis using ELISA of vascular endothelial growth factor and basic fibroblast growth factor in human colorectal cancer, liver metastasis of colorectal cancer and hepatocellular carcinoma. World J Gastroenterol 2006; 12: 3782-3783.
    • (2006) World J Gastroenterol , vol.12 , pp. 3782-3783
    • Mathonnet, M.1    Descottes, B.2    Valleix, D.3    Labrousse, F.4    Truffinet, V.5    Denizot, Y.6
  • 14
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • SHARP Investigators Study Group
    • Llovet JM, Ricci S, Mazzaferro V etal; SHARP Investigators Study Group. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-390.
    • (2008) N Engl J Med , vol.359 , pp. 378-390
    • Llovet, J.M.1    Ricci, S.2    Mazzaferro, V.3
  • 15
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
    • Cheng AL, Kang YK, Chen Z etal. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009; 10: 25-34.
    • (2009) Lancet Oncol , vol.10 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3
  • 16
    • 2542473135 scopus 로고    scopus 로고
    • Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumor progression and apoptosis
    • Huynh H, Nguyen TT, Chow KH, Tan PH, Soo KC, Tran E. Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumor progression and apoptosis. BMC Gastroenterol 2003; 3: 19.
    • (2003) BMC Gastroenterol , vol.3 , pp. 19
    • Huynh, H.1    Nguyen, T.T.2    Chow, K.H.3    Tan, P.H.4    Soo, K.C.5    Tran, E.6
  • 17
    • 33749836283 scopus 로고    scopus 로고
    • Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors
    • Yoshida T, Hisamoto T, Akiba J etal. Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors. Oncogene 2006; 25: 6056-6066.
    • (2006) Oncogene , vol.25 , pp. 6056-6066
    • Yoshida, T.1    Hisamoto, T.2    Akiba, J.3
  • 18
    • 34249900712 scopus 로고    scopus 로고
    • High serum vascular endothelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies
    • Poon RT, Lau C, Pang R, Ng KK, Yuen J, Fan ST. High serum vascular endothelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies. Ann Surg Oncol 2007; 14: 1835-1845.
    • (2007) Ann Surg Oncol , vol.14 , pp. 1835-1845
    • Poon, R.T.1    Lau, C.2    Pang, R.3    Ng, K.K.4    Yuen, J.5    Fan, S.T.6
  • 19
    • 34447326697 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor-α: a novel therapeutic target in human hepatocellular cancer
    • Stock P, Monga D, Tan X, Micsenyi A, Loizos N, Monga SP. Platelet-derived growth factor receptor-α: a novel therapeutic target in human hepatocellular cancer. Mol Cancer Ther 2007; 6: 1932-1941.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1932-1941
    • Stock, P.1    Monga, D.2    Tan, X.3    Micsenyi, A.4    Loizos, N.5    Monga, S.P.6
  • 20
    • 33645740560 scopus 로고    scopus 로고
    • Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: importance of angiopoietin-2 and hypoxia-induced factor-1α
    • Wada H, Nagano H, Yamamoto H etal. Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: importance of angiopoietin-2 and hypoxia-induced factor-1α. Liver Int 2006; 26: 414-423.
    • (2006) Liver Int , vol.26 , pp. 414-423
    • Wada, H.1    Nagano, H.2    Yamamoto, H.3
  • 21
    • 79955433548 scopus 로고    scopus 로고
    • Targeted therapies for hepatocellular carcinoma
    • Villanueva A, Llovet JM. Targeted therapies for hepatocellular carcinoma. Gastroenteriology 2011; 140: 1410-1426.
    • (2011) Gastroenteriology , vol.140 , pp. 1410-1426
    • Villanueva, A.1    Llovet, J.M.2
  • 22
    • 60849136064 scopus 로고    scopus 로고
    • Combined approach to hepatollular carcinoma: a new treatment concept for nonresectable disease
    • Strebel BM, Dufour JF. Combined approach to hepatollular carcinoma: a new treatment concept for nonresectable disease. Expert Rev Anticancer Ther 2008; 8: 1743-1749.
    • (2008) Expert Rev Anticancer Ther , vol.8 , pp. 1743-1749
    • Strebel, B.M.1    Dufour, J.F.2
  • 23
    • 79960805810 scopus 로고    scopus 로고
    • Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma
    • Kudo M, Imanaka K, Chida N etal. Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma. Eur J Cancer 2011; 47: 2117-2127.
    • (2011) Eur J Cancer , vol.47 , pp. 2117-2127
    • Kudo, M.1    Imanaka, K.2    Chida, N.3
  • 24
    • 28844480321 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • Practice Guidelines Committee, American Association for the Study of Liver Diseases.
    • Bruix J, Sherman M; Practice Guidelines Committee, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma. Hepatology 2005; 42: 1208-1236.
    • (2005) Hepatology , vol.42 , pp. 1208-1236
    • Bruix, J.1    Sherman, M.2
  • 25
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA etal; European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 2000; 92: 205-216.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 26
    • 44649173785 scopus 로고    scopus 로고
    • A critical appraisal of propensity-score matching in the medical literature between 1996 and 2003
    • Austin PC. A critical appraisal of propensity-score matching in the medical literature between 1996 and 2003. Stat Med 2008; 27: 2037-2049.
    • (2008) Stat Med , vol.27 , pp. 2037-2049
    • Austin, P.C.1
  • 27
    • 3543135271 scopus 로고    scopus 로고
    • Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group
    • D'Agostino RB Jr. Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. Stat Med 1998; 17: 2265-2281.
    • (1998) Stat Med , vol.17 , pp. 2265-2281
    • D'Agostino Jr., R.B.1
  • 30
    • 7244222908 scopus 로고    scopus 로고
    • High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: a prospective study
    • Poon RT, Lau C, Yu WC, Fan ST, Wong J. High serum levels of vascular endothelial growth factor predict poor response to transarterial chemoembolization in hepatocellular carcinoma: a prospective study. Oncol Rep 2004; 11: 1077-1084.
    • (2004) Oncol Rep , vol.11 , pp. 1077-1084
    • Poon, R.T.1    Lau, C.2    Yu, W.C.3    Fan, S.T.4    Wong, J.5
  • 31
    • 77955699976 scopus 로고    scopus 로고
    • Loco-regional treatment of hepatocellular carcinoma
    • Lencioni R. Loco-regional treatment of hepatocellular carcinoma. Hepatology 2010; 52: 762-773.
    • (2010) Hepatology , vol.52 , pp. 762-773
    • Lencioni, R.1
  • 32
    • 84875614336 scopus 로고    scopus 로고
    • A phase II randomized, double-blind, placebo-controlled study of sorafenib or placebo in combination with transarterial chemoembolization (TACE) performed with DC bead and doxorubicin for intermediate stage hepatocellular carcinoma (HCC). [Updated 29 October 2012; cited 26 January 2013]. Available from URL:
    • A phase II randomized, double-blind, placebo-controlled study of sorafenib or placebo in combination with transarterial chemoembolization (TACE) performed with DC bead and doxorubicin for intermediate stage hepatocellular carcinoma (HCC). [Updated 29 October 2012; cited 26 January 2013]. Available from URL: http://clinicaltrials.gov/ct2/show/NCT00855218?term=sorafenib+TACE&rank=10
  • 33
    • 84875604807 scopus 로고    scopus 로고
    • START: Study in Asia of the combination of TACE (transcatheter arterial chemoembolization) with sorafenib in patients with hepatocellular carcinoma trial. ASCO Gastrointestinal Cancers Symposium, Orlando, FL, USA.
    • Chao Y, Yoon J, Li C etal. START: Study in Asia of the combination of TACE (transcatheter arterial chemoembolization) with sorafenib in patients with hepatocellular carcinoma trial. 2010 ASCO Gastrointestinal Cancers Symposium, Orlando, FL, USA.
    • (2010)
    • Chao, Y.1    Yoon, J.2    Li, C.3
  • 34
    • 59449089100 scopus 로고    scopus 로고
    • Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response
    • Yau T, Chan P, Ng KK etal. Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response. Cancer 2009; 115: 428-436.
    • (2009) Cancer , vol.115 , pp. 428-436
    • Yau, T.1    Chan, P.2    Ng, K.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.