KSRP silencing favors neural differentiation of P19 teratocarcinoma cells

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Volumn 1829, Issue 5, 2013, Pages 469-479

  Giovarelli, Matteo ^a,b   Bucci, Gabriele ^c   Pasero, Michela ^a,b   Gherzi, Roberto ^d   Briata, Paola ^d  

^a UNIVERSITY OF GENOA   (Italy)

^b CENTRO DI BIOTECNOLOGIE AVANZATE   (Italy)

^c ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

MicroRNA maturation; MRNA degradation; Neural differentiation; RNA binding protein

Indexed keywords

MICRORNA; MICRORNA 200; PROTEIN KSRP; RNA BINDING PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYONAL CARCINOMA STEM CELL; MESENCHYME CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE, TUMOR; GENE SILENCING; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; MESENCHYMAL STROMAL CELLS; MICE; MICRORNAS; NEUROGENESIS; RNA PRECURSORS; RNA STABILITY; RNA-BINDING PROTEINS; TERATOCARCINOMA; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSCRIPTOME;

EID: 84875606627     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2013.02.008     Document Type: Article

References (34)

1. Halbeisen R.E., Galgano A., Scherrer T., Gerber A.P. Post-transcriptional gene regulation: from genome-wide studies to principles. Cell. Mol. Life Sci. 2008, 65:798-813.
2. Mansfield K.D., Keene J.D. The ribonome: a dominant force in gene expression. Biol. Cell 2009, 101:169-181.
3. Keene J.D. Global regulation and dynamics of ribonucleic acid. Endocrinology 2010, 151:1391-1397.
4. Kapeli K., Yeo G.W. Genome-wide approaches to dissect the roles of RNA binding proteins in translational control: implications for neurological diseases. Front. Neurosci. 2012, 6:144.
5. Agami R. microRNAs, RNA binding proteins and cancer. Eur. J. Clin. Invest. 2010, 40:370-374.
6. Briata P., Chen C.-Y., Ramos A., Gherzi R. Functional and molecular insights into KSRP function in mRNA decay. Biochim. Biophys. Acta Gene Regul. Mech. 2012, 10.1016/j.bbagrm.2012.11.003.
7. Briata P., Lin W.J., Giovarelli M., Pasero M., Chou C.F., Trabucchi M., Rosenfeld M.G., Chen C.-Y., Gherzi R. PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis. Cell Death Differ. 2012, 19:478-487.
8. Pasero M., Giovarelli M., Bucci G., Gherzi R., Briata P. Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation. Cell Rep. 2012, 2:1159-1168.
9. Jones-Villeneuve E.M., Rudnicki M.A., Harris J.F., McBurney M.W. Retinoic acid-induced neural differentiation of embryonal carcinoma cells. Mol. Cell. Biol. 1983, 3:2271-2279.
10. Bain G., Ray W.J., Yao M., Gottlieb D.I. From embryonal carcinoma cells to neurons: the P19 pathway. Bioessays 1994, 16:343-348.
11. Negraes P.D., Schwindt T.T., Trujillo C.A., Ulrich H. Neural differentiation of P19 carcinoma cells and primary neurospheres: cell morphology, proliferation, viability, and functionality. Curr. Protoc. Stem Cell Biol. 2012, 20. (2D.9.1-2D.9.22).
12. Bertrand N., Castro D.S., Guillemot F. Proneural genes and the specification of neural cell types. Nat. Rev. Neurosci. 2002, 3:517-530.
13. Vierbuchen T., Ostermeier A., Pang Z.P., Kokubu Y., Sudhof T.C., Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 2010, 463:1035-1041.
14. De Santa F., Totaro M.G., Prosperini E., Notarbartolo S., Testa G., Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007, 130:1083-1094.
15. Agger K., Cloos P.A., Christensen J., Pasini D., Rose S., Rappsilber J., Issaeva I., Canaani E., Salcini A.E., Helin K. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 2007, 449:731-734.
16. Lan F., Bayliss P.E., Rinn J.L., Whetstine J.R., Wang J.K., Chen S., Iwase S., Alpatov R., Issaeva I., Canaani E., Roberts T.M., Chang H.Y., Shi Y. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature 2007, 449:689-694.
17. Jepsen K., Solum D., Zhou T., McEvilly R.J., Kim H.J., Glass C.K., Hermanson O., Rosenfeld M.G. SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature 2007, 450:415-419.
18. Dai J.P., Lu J.Y., Zhang Y., Shen Y.F. Jmjd3 activates Mash1 gene in RA-induced neuronal differentiation of P19 cells. J. Cell. Biochem. 2010, 110:1457-1463.
19. Briata P., Forcales S.V., Ponassi M., Corte G., Chen C.Y., Karin M., Puri P.L., Gherzi R. p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts. Mol. Cell 2005, 20:891-903.
20. Gherzi R., Lee K.Y., Briata P., Wegmuller D., Moroni C., Karin M., Chen C.Y. A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol. Cell 2004, 14:571-583.
21. Yan Y., Yang J., Bian W., Jing N. Mouse nestin protein localizes in growth cones of P19 neurons and cerebellar granule cells. Neurosci. Lett. 2001, 302:89-92.
22. Wei Y., Harris T., Childs G. Global gene expression patterns during neural differentiation of P19 embryonic carcinoma cells. Differentiation 2002, 70:204-219.
23. Brade T., Kumar S., Cunningham T.J., Chatzi C., Zhao X., Cavallero S., Li P., Sucov H.M., Ruiz-Lozano P., Duester G. Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial Igf2. Development 2011, 138:139-148.
24. Smirnova L., Gräfe A., Seiler A., Schumacher S., Nitsch R., Wulczyn F.G. Regulation of miRNA expression during neural cell specification. Eur. J. Neurosci. 2005, 21:1469-1477.
25. Laferrière N.B., Brown D.L. Effects of taxol on the polymerization and posttranslational modification of class III beta-tubulin in P19 embryonal carcinoma cells. Biochem. Cell Biol. 1995, 73:687-694.
26. Mootha V.K., Lindgren C.M., Eriksson K.F., Subramanian A., Sihag S., Lehar J., Puigserver P., Carlsson E., Ridderstråle M., Laurila E., Houstis N., Daly M.J., Patterson N., Mesirov J.P., Golub T.R., Tamayo P., Spiegelman B., Lander E.S., Hirschhorn J.N., Altshuler D., Groop L.C. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat. Genet. 2003, 34:267-273.
27. Subramanian A., Tamayo P., Mootha V.K., Mukherjee S., Ebert B.L., Gillette M.A., Paulovich A., Pomeroy S.L., Golub T.R., Lander E.S., Mesirov J.P. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:15545-15550.
28. Vojtek A.B., Taylor J., De Ruiter S.L., Yu J.Y., Figueroa C., Kwok R.P., Turner D.L. Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation. Mol. Cell. Biol. 2003, 23:4417-4427.
29. Trabucchi M., Briata P., Filipowicz W., Rosenfeld M.G., Ramos A., Gherzi R. How to control miRNA maturation?. RNA Biol. 2009, 6:536-540.
30. Huang B., Li W., Zhao B., Xia C., Liang R., Ruan K., Jing N., Jin Y. MicroRNA expression profiling during neural differentiation of mouse embryonic carcinoma P19 cells. Acta Biochim. Biophys. Sin. 2009, 41:231-236.
31. Yoshizawa M., Taguchi Y.H., Yasuda J. Inference of gene regulation via miRNAs during ES cell differentiation using MiRaGE method. Int. J. Mol. Sci. 2011, 12:9265-9276.
32. Cochrane D.R., Howe E.N., Spoelstra N.S., Richer J.K. Loss of miR-200c: a marker of aggressiveness and chemoresistance in female reproductive cancers. J. Oncol. 2010, 2010:821717.
33. Brabletz S., Brabletz T. The ZEB/miR-200 feedback loop-a motor of cellular plasticity in development and cancer?. EMBO Rep. 2010, 11:670-677.
34. Kerosuo L., Bronner-Fraser M. What is bad in cancer is good in the embryo: importance of EMT in neural crest development. Semin. Cell Dev. Biol. 2012, 23:320-332.