Transport and uptake of immunogenic lipids

Molecular Immunology

Volumn 55, Issue 2, 2013, Pages 179-181

  Freigang, Stefan ^a   Kain, Lisa ^a   Teyton, Luc ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Cellular uptake; Degradation; Lipid transport; NKT cells; Scavenger receptors; Vaccine

Indexed keywords

GLYCOLIPID;

ADAPTIVE IMMUNITY; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MATURATION; CELL STIMULATION; DENDRITIC CELL; DYSLIPIDEMIA; HUMAN; INNATE IMMUNITY; LIPID METABOLISM; LIPID TRANSPORT; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANTIGENS, CD1D; BIOLOGICAL TRANSPORT; DENDRITIC CELLS; GALACTOSYLCERAMIDES; GLYCOLIPIDS; HUMANS; LIPID METABOLISM; LIPIDS; NATURAL KILLER T-CELLS;

EID: 84875578891     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.10.016     Document Type: Review

References (4)

1. Freigang S., et al. Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice. Journal of Clinical Investigation 2010, 120:1873-1884. 10.1172/JCI40451.
2. Freigang S., et al. Scavenger receptors target glycolipids for NKT cell activation. Journal of Clinical Investigation 2012, 122(11):3943-3954. 10.1172/JCI62267.
3. Schneiders F.L., et al. Clinical experience with alpha-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection. Clinical Immunology 2011, 140:130-141. 10.1016/j.clim.2010.11.010.
4. van den Elzen P., et al. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature 2005, 437:906-910. 10.1038/nature04001.