1H NMR metabolic profiling of human serum associated with benign and malignant gallstone diseases

Metabolomics

Volumn 9, Issue 2, 2013, Pages 515-528

  Sonkar, Kanchan ^a   Behari, Anu ^a   Kapoor, V K ^a   Sinha, Neeraj ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Chronic cholecystitis; Gallbladder cancer; Metabolic profiling; Metabonomics; NMR spectroscopy; PLS DA; Serum; Xanthogranulomatous cholecystitis

Indexed keywords

AMINO ACID; GLUCOSE; LACTIC ACID; LOW DENSITY LIPOPROTEIN; PYRUVIC ACID; VERY LOW DENSITY LIPOPROTEIN;

ADULT; ARTICLE; BLOOD ANALYSIS; CANCER DIAGNOSIS; CHEMOMETRICS; CHOLECYSTITIS; CHRONIC CHOLECYSTITIS; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; GALLBLADDER CARCINOMA; GLUCOSE BLOOD LEVEL; HUMAN; LACTATE BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; METABOLOMICS; PROTON NUCLEAR MAGNETIC RESONANCE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SERUM; XANTHOGRANULOMATOUS CHOLECYSTITIS;

EID: 84875542669     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-012-0468-7     Document Type: Article

References (69)

1. Baracos, V. E., & Mackenzie, M. L. (2006). Investigations of branched-chain amino acids and their metabolites in animal models of cancer. The Journal of Nutrition, 136(1), 237S-242S.
2. Bathe, O. F., Shaykhutdinov, R., Kopciuk, K., Weljie, A. M., McKay, A., Sutherland, F. R., et al. (2011). Feasibility of identifying pancreatic cancer based on serum metabolomics. Cancer Epidemiology Biomarkers and Prevention, 20(1), 140-147.
3. Bathen, T. F., Sitter, B., Sjøbakk, T. E., Tessem, M. B., & Gribbestad, I. S. (2010). Magnetic resonance metabolomics of intact tissue: A biotechnological tool in cancer diagnostics and treatment evaluation. Cancer Research, 70(17), 6692-6696.
4. Ben Sellem, D., Elbayed, K., Neuville, A., Moussallieh, F. M., Lang-Averous, G., Piotto, M., et al. (2011). Metabolomic characterization of ovarian epithelial carcinomas by HRMAS-NMR spectroscopy. Journal of Oncology, 2011, 174019.
5. Benbow, E. W. (1990). Xanthogranulomatous cholecystitis. British Journal of Surgery, 77(3), 255-256.
6. Bertini, I., Cacciatore, S., Jensen, B. V., Schou, J. V., Johansen, J. S., Kruhøffer, M., et al. (2012). Metabolomic NMR fingerprinting to identify and predict survival of patients with metastatic colorectal cancer. Cancer Research, 72(1), 356-364.
7. Bharti, S., Behari, A., Kapoor, V., Kumari, N., Krishnani, N., & Roy, R. (2012a). Magic angle spinning NMR spectroscopic metabolic profiling of gall bladder tissues for differentiating malignant from benign disease. Metabolomics, 1-18.
8. Bharti, S., Jaiswal, V., Ghoshal, U., Ghoshal, U., Baijal, S., Roy, R., et al. (2012b). Metabolomic profiling of amoebic and pyogenic liver abscesses: an in vitro NMR study. Metabolomics, 8(4), 540-555.
9. Carrola, J., Rocha, C. M., Barros, A. S., Gil, A. M., Goodfellow, B. J., Carreira, I. M., et al. (2011). Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine. Journal of Proteome Research, 10(1), 221-230.
10. Chan, E. C., Koh, P. K., Mal, M., Cheah, P. Y., Eu, K. W., Backshall, A., et al. (2009). Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS). Journal of Proteome Research, 8(1), 352-361.
11. Chang, B. J., Kim, S. H., Park, H. Y., Lim, S. W., Kim, J., Lee, K. H., et al. (2010). Distinguishing xanthogranulomatous cholecystitis from the wall-thickening type of early-stage gallbladder cancer. Gut and Liver, 4(4), 518-523.
12. Cheng, L. L., Anthony, D. C., Comite, A. R., Black, P. M., Tzika, A. A., & Gonzalez, R. G. (2000). Quantification of microheterogeneity in glioblastoma multiforme with ex vivo high-resolution magic-angle spinning (HRMAS) proton magnetic resonance spectroscopy. Journal of Neuro-Oncology, 2(2), 87-95.
13. Curthoys, N. P., & Watford, M. (1995). Regulation of glutaminase activity and glutamine metabolism. Annual Review of Nutrition, 15(1), 133-159.
14. Divino Filho, J. C., Bárány, P., Stehle, P., Fürst, P., & Bergström, J. (1997). Free amino-acid levels simultaneously collected in plasma, muscle, and erythrocytes of uraemic patients. Nephrology Dialysis Transplantation, 12(11), 2339-2348.
15. Erol, A. (2005). Retrograde regulation due to mitochondrial dysfunction may be an important mechanism for carcinogenesis. Medical Hypotheses, 65(3), 525-529.
16. Eslick, G. D. (2010). Epidemiology of gallbladder cancer. Gastroenterology Clinics of North America, 39(2), 307-330.
17. Forslund, A. H., Hambraeus, L., van Beurden, H., Holmbäck, U., El-Khoury, A. E., Hjorth, G., et al. (2000). Inverse relationship between protein intake and plasma free amino acids in healthy men at physical exercise. American Journal of Physiology: Endocrinology And Metabolism, 278(5), E857-E867.
18. 1H NMR metabonomics of serum explored by use of a microflow NMR probe. Journal of Proteome Research, 10(4), 1765-1771.
19. Goldin, R. D., & Roa, J. C. (2009). Gallbladder cancer: a morphological and molecular update. Histopathology, 55(2), 218-229.
20. Gupta, S. K., & Shukla, V. K. (2005). Gall Bladder cancer etiopathology and treatment. Health Administrator, 17(1), 134-142.
21. Hanai, T. (1991). Liquid chromatography in biomedical analysis. Elsevier: Amsterdam.
22. Hariharan, D., Saied, A., & Kocher, H. M. (2008). Analysis of mortality rates for gallbladder cancer across the world. HPB (Oxford), 10(5), 327-331.
23. Holroyde, C. P., Axelrod, R. S., Skutches, C. L., Haff, A. C., Paul, P., & Reichard, G. A. (1979). Lactate metabolism in patients with metastatic colorectal cancer. Cancer Research, 39(12), 4900-4904.
24. ICMR, (1996). Annual report of population based cancer registries of the National Cancer Registry Programme (1993). In I. C. o. M. Research (Ed.), (pp. 18). New Delhi: ICMR Publication.
25. Jayalakshmi, K., Sonkar, K., Behari, A., Kapoor, V. K., & Sinha, N. (2009). Solid state (13)C NMR analysis of human gallstones from cancer and benign gall bladder diseases. Solid State Nuclear Magnetic Resonance, 36(1), 60-65.
26. 1H NMR spectroscopy. NMR in Biomedicine, 24(4), 335-342.
27. Kapoor, V. K., & McMichael, A. J. (2003). Gallbladder cancer: an 'Indian' disease. National Medical Journal of India, 16(4), 209-213.
28. Klomp, D. W. J., van de Bank, B. L., Raaijmakers, A., Korteweg, M. A., Possanzini, C., Boer, V. O., et al. (2011). 31P MRSI and 1H MRS at 7 T: Initial results in human breast cancer. NMR in Biomedicine, 24(10), 1337-1342.
29. Kruse, S., Kvalheim, O. M., Gadeholt, G., Halsteinslid, L., & Sletten, E. (1991). Multivariate analysis of proton NMR spectra of serum from rabbits: Monitoring progressive growth of implanted VX-2 carcinoma. Chemometrics and Intelligent Laboratory Systems, 11(2), 191-196.
30. Lai, H.-S., Lee, J.-C., Lee, P.-H., Wang, S.-T., & Chen, W.-J. (2005). Plasma free amino acid profile in cancer patients. Seminars in Cancer Biology, 15(4), 267-276.
31. 1H MR spectroscopy for assessment of apoptosis in cervical carcinomas. BMC Cancer, 7(1), 11.
32. MacKinnon, N., Ge, W., Khan, A. P., Somashekar, B. S., Tripathi, P., Siddiqui, J., et al. (2012a). Variable reference alignment: An improved peak alignment protocol for NMR spectral data with large intersample variation. Analytical Chemistry, 84(12), 5372-5379.
33. MacKinnon, N., Khan, A., Chinnaiyan, A., Rajendiran, T., & Ramamoorthy, A. (2012b). Androgen receptor activation results in metabolite signatures of an aggressive prostate cancer phenotype: An NMR-based metabonomics study. Metabolomics, 1-11.
34. Miyagi, Y., Higashiyama, M., Gochi, A., Akaike, M., Ishikawa, T., Miura, T., et al. (2011). Plasma free amino acid profiling of five types of cancer patients and its application for early detection. PLoS ONE, 6(9), e24143.
35. Nicholson, J. K., & Lindon, J. C. (2008). Systems biology: Metabonomics. Nature, 455(7216), 1054-1056.
36. 1H-NMR-based metabonomics. International Journal of Cancer, 113(5), 782-788.
37. Pandey, M., Vishwakarma, R. A., Gautam, A., Khatri, A. K., Roy, S. K., & Shukla, V. K. (1995). Bile, bacteria and gallbladder carcinogenesis. Journal of Surgical Oncology, 58, 282-283.
38. Pisters, P. W. T., & Brennan, M. F. (1990). Amino acid metabolism in human cancer cachexia. Annual Review of Nutrition, 10(1), 107-132.
39. Rautray, T. R., Vijayan, V., Sudarshan, M., & Panigrahi, S. (2009). Analysis of blood and tissue in gallbladder cancer. Nuclear Instruments & Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 267(17), 2878-2883.
40. Righi, V., Durante, C., Cocchi, M., Calabrese, C., Di Febo, G., Lecce, F., et al. (2009a). Discrimination of healthy and neoplastic human colon tissues by ex vivo HR-MAS NMR spectroscopy and chemometric analyses. Journal of Proteome Research, 8(4), 1859-1869.
41. 1H HR-MAS and genomic analysis of human tumor biopsies discriminate between high and low grade astrocytomas. NMR in Biomedicine, 22(6), 629-637.
42. Roa, I., Araya, J. C., Villaseca, M., De Aretxabala, X., Riedemann, P., Endoh, K., et al. (1996). Preneoplastic lesions and gallbladder cancer: An estimate of the period required for progression. Gastroenterology, 111(1), 232-236.
43. Roa, I., de Aretxabala, X., & Wistuba, I. I. (2009). Histopathology and molecular pathogenesis of gallbladder cancer. In C. R. Thomos & C. D. Fuller (Eds.), Biliary Tract and Gallbladder Cancer: Diagnosis and Therapy. New York, NY: Demos Medical Publishing.
44. 1H high resolution magic angle spinning (HRMAS) NMR spectroscopy. Journal of Proteome Research, 9(1), 319-332.
45. Rocha, C. M., Carrola, J., Barros, A., Gil, A. M., Goodfellow, B. J., Carreira, I. M., et al. (2011). Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of blood plasma. Journal of Proteome Research, 10(9), 4314-4324.
46. Schirmer, B. D., Winters, K. L., & Edlich, R. F. (2005). Cholelithiasis and cholecystitis. Journal of Long-Term Effects of Medical Implants, 15(3), 329-338.
47. Seierstad, T., Roe, K., Sitter, B., Halgunset, J., Flatmark, K., Ree, A. H., et al. (2008). Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy. Molecular Cancer, 7, 33.
48. Semenza, G. L. (2008). Tumor metabolism: cancer cells give and take lactate. The Journal of Clinical Investigation, 118(12), 3835-3837.
49. Sitter, B., Bathen, T., Hagen, B., Arentz, C., Skjeldestad, F. E., & Gribbestad, I. S. (2004). Cervical cancer tissue characterized by high-resolution magic angle spinning MR spectroscopy. Magnetic Resonance Materials in Physics, Biology and Medicine, 16(4), 174-181.
50. Sitter, B., Lundgren, S., Bathen, T. F., Halgunset, J., Fjosne, H. E., & Gribbestad, I. S. (2006). Comparison of HR MAS MR spectroscopic profiles of breast cancer tissue with clinical parameters. NMR in Biomedicine, 19(1), 30-40.
51. Sitter, B., Sonnewald, U., Spraul, M., Fjosne, H. E., & Gribbestad, I. S. (2002). High-resolution magic angle spinning MRS of breast cancer tissue. NMR in Biomedicine, 15(5), 327-337.
52. Somashekar, B. S., Kamarajan, P., Danciu, T., Kapila, Y. L., Chinnaiyan, A. M., Rajendiran, T. M., et al. (2011). Magic angle spinning NMR-based metabolic profiling of head and neck squamous cell carcinoma tissues. Journal of Proteome Research, 10(11), 5232-5241.
53. Srivastava, S., Roy, R., Gupta, V., Tiwari, A., Srivastava, A., & Sonkar, A. (2011). Proton HR-MAS MR spectroscopy of oral squamous cell carcinoma tissues: An ex vivo study to identify malignancy induced metabolic fingerprints. Metabolomics, 7(2), 278-288.
54. Srivastava, M., Sharma, A., Kapoor, V. K., & Nagana Gowda, G. A. (2008). Stones from cancerous and benign gallbladders are different: A proton nuclear magnetic resonance spectroscopy study. Hepatology Research, 38(10), 997-1005.
55. Stenman, K., Stattin, P., Stenlund, H., Riklund, K., Grobner, G., & Bergh, A. (2011). H HRMAS NMR derived bio-markers related to tumor grade, tumor cell fraction, and cell proliferation in prostate tissue samples. Biomark Insights, 6, 39-47.
56. Stenman, K., Surowiec, I., Antti, H., Riklund, K., Stattin, P., Bergh, A., et al. (2010). Detection of local prostate metabolites by HRMAS NMR spectroscopy: A comparative study of human and rat prostate tissues. Magnetic Resonance Insights, 4, 27-41.
57. Tan, Y., Yin, P., Tang, L., Xing, W., Huang, Q., Cao, D., et al. (2012). Metabolomics study of stepwise hepatocarcinogenesis from the model rats to patients: potential biomarkers effective for small hepatocellular carcinoma diagnosis. Molecular & Cellular Proteomics, 11(2), 111. 010694.
58. 1H magic angle spinning (MAS) NMR spectra. NMR in Biomedicine, 13(2), 64-71.
59. Tazuma, S., & Kajiyama, G. (2001). Carcinogenesis of malignant lesions of the gall bladder. The impact of chronic inflammation and gallstones. Langenbecks Archives of Surgery, 386(3), 224-229.
60. Tripathi, P., Bala, L., Saxena, R., Yachha, S. K., Roy, R., & Khetrapal, C. L. (2009). 1H NMR spectroscopic study of blood serum for the assessment of liver function in liver transplant patients. The Journal of Gastrointestinal and Liver Diseases, 18(3), 329-336.
61. Tripathi, P., Kamarajan, P., Somashekar, B. S., MacKinnon, N., Chinnaiyan, A. M., Kapila, Y. L., et al. (2012). Delineating metabolic signatures of head and neck squamous cell carcinoma: Phospholipase A2, a potential therapeutic target. The International Journal of Biochemistry & Cell Biology, 44(11), 1852-1861.
62. van Asten, J., Cuijpers, V., Hulsbergen-van de Kaa, C., Soede-Huijbregts, C., Witjes, J., Verhofstad, A., et al. (2008). High resolution magic angle spinning NMR spectroscopy for metabolic assessment of cancer presence and Gleason score in human prostate needle biopsies. Magnetic Resonance Materials in Physics, Biology and Medicine, 21(6), 435-442.
63. Vander Heiden, M. G., Cantley, L. C., & Thompson, C. B. (2009). Understanding the Warburg effect: The metabolic requirements of cell proliferation. Science, 324(5930), 1029-1033.
64. 1H NMR spectroscopy of intact liver and kidney: Optimization of sample preparation procedures and biochemical stability of tissue during spectral acquisition. Analytical Biochemistry, 282(1), 16-23.
65. 1H NMR metabonomics to breast cancer characterization and detection. Progress in Nuclear Magnetic Resonance Spectroscopy, 47(3), 165-174.
66. Wright, A. J., Fellows, G. A., Griffiths, J. R., Wilson, M., Bell, B. A., & Howe, F. A. (2010). Ex vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers. Mol Cancer, 9, 66-83.
67. 1H NMR spectroscopy in conjunction with multivariate data analysis. Journal of Proteome Research, 6(7), 2605-2614.
68. Yang, T., Zhang, B.-H., Zhang, J., Zhang, Y.-J., Jiang, X.-Q., & Wu, M.-C. (2007b). Surgical treatment of xanthogranulomatous cholecystitis: Experience in 33 cases. Hepatobiliary & Pancreatic Diseases International, 6(5), 504-508.
69. 1H NMR metabonomic analysis in renal cell carcinoma: A possible diagnostic tool. Journal of Proteome Research, 9(8), 4038-4044.