Production of cyclosporine a by submerged fermentation from a local isolate of Penicillium fellutanum

Indian Journal of Pharmaceutical Sciences

Volumn 74, Issue 4, 2012, Pages 372-374

  Anjum, Tehmina ^a   Azam, Asma ^a   Irum, Wajiha ^a  

^a UNIVERSITY OF THE PUNJAB   (Pakistan)

Author keywords

Cyclosporine A; high performance liquid chromatography; Penicillium

Indexed keywords

CYCLOSPORIN A; GLUCOSE; PEPTONE; POTASSIUM CHLORIDE;

ARTICLE; CHROMATOGRAPHY; DRUG MANUFACTURE; FUNGUS ISOLATION; GUAVA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PENICILLIUM; PENICILLIUM FELLUTANUM; SUBMERGED FERMENTATION;

EID: 84875525998     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.107082     Document Type: Article

References (9)

1. Budavari SM, Neal JO, Smith A, Heckelman PE. The Merck Index. An Encyclopedia of Chemicals, Drugs and Biologicals. 12th ed. New Jersey: Merck Research Laboratory; 1996, p. 1498
2. Sallam LA, El-Refai AM, Hamdi AH, El-Minofi HA, Abd-Elsalam I.S. Studies on the application of immobilization technique for the of cyclosporin A by a local strain of Aspergillus terreus. J Gen Appl Microbiol 2005;51:143-9
3. Riley MR, Hebel KE. Drug Facts and Comparisons. Vol. 52. St. Louis. Wolters Kluwer; 2000. p. 1553-8
4. Dreyfuss M, Harri E, Hofmann H, Kobel H, Pache W, Tscherter H. Cyclosporin A and C. New metabolites from Trichoderma polysporum. Eur J Appl Microbiol 1976;3:125-33
5. Koble H, Traber R. Directed biosynthesis of cyclosporins. Eur J Appl Microbiol Biotechnol 1982;14:237-40
6. Borel JF, Feurer C, Magnée C, Stähelin H. Effects of the new antilymphocytic peptide cyclosporin A in animals. Immunology ;32:1017-25
7. Agathos SN, Marshell JW, Maraiti C, Parekh R, Modhosingh C. Physiological and genetic factors for process development of cyclosporin fermentation. J Ind Microbiol 1986;1:39-48
8. Balakrishnan K, Pandey A. Growth and cyclosporin A production by an isolated strain of Tolypocladium inflatum. Folia Microbiol(Praha) 1996;41:401-6
9. Sallam LA, El-Refai AM, Hamdy AH, El-Minofi HA, Abdel-Salam I.S. Role of some fermentation parameters on cyclosporin A production by a new isolate of Aspergillus terreus. J Gen Appl Microbiol ;49:321-8