Effects of Escherichia coli heat-stable enterotoxin and guanylin on the barrier integrity of intestinal epithelial T84 cells

Veterinary Immunology and Immunopathology

Volumn 152, Issue 1-2, 2013, Pages 78-81

  Nakashima, Ryo ^a   Kamata, Yoichi ^b   Nishikawa, Yoshikazu ^a  

^a Osaka Prefecture University   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Enterotoxin; Intestinal barrier; Tight junction

Indexed keywords

AMINO ACID; BACTERIAL TOXIN; ENTEROTOXIN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GUANYLATE CYCLASE; GUANYLIN; HEAT STABLE ENTEROTOXIN; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CELL MEMBRANE PERMEABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTRIC RESISTANCE; ENZYME ACTIVATION; ESCHERICHIA COLI; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; MONOLAYER CULTURE; NONHUMAN; PERMEABILITY BARRIER; TRANSEPITHELIAL ELECTRICAL RESISTANCE;

BACTERIAL TOXINS; CELL LINE; CELL MEMBRANE PERMEABILITY; ELECTRIC IMPEDANCE; ENTEROTOXINS; EPITHELIAL CELLS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; GASTROINTESTINAL HORMONES; HUMANS; INTESTINE, SMALL; NATRIURETIC PEPTIDES;

ESCHERICHIA COLI;

EID: 84875492950     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2012.09.026     Document Type: Article

References (9)

1. Bonazzi M., Cossart P. Impenetrable barriers or entry portals? The role of cell-cell adhesion during infection. J. Cell Biol. 2011, 195:348-357.
2. Croxen M.A., Finlay B.B. Molecular mechanisms of Escherichia coli pathogenicity. Nat. Rev. Microbiol. 2010, 8:26-38.
3. Fasano A. Cellular microbiology: can we learn cell physiology from microorganisms?. Am. J. Physiol. 1999, 276:C765-C776.
4. Guttman J.A., Finlay B.B. Tight junctions as targets of infectious agents. Biochim. Biophys. Acta 2009, 1788:832-841.
5. Hofman P. Pathological interactions of bacteria and toxins with the gastrointestinal epithelial tight junctions and/or the zonula adherens: an update. Cell. Mol. Biol. 2003, 49:65-75.
6. Kreisberg R.B., Harper J., Strauman M.C., Marohn M., Clements J.D., Nataro J.P. Induction of increased permeability of polarized enterocyte monolayers by enterotoxigenic Escherichia coli heat-labile enterotoxin. Am. J. Trop. Med. Hyg. 2011, 84:451-455.
7. Soong G., Parker D., Magargee M., Prince A.S. The type III toxins of Pseudomonas aeruginosa disrupt epithelial barrier function. J. Bacteriol. 2008, 190:2814-2821.
8. Taxt A., Aasland R., Sommerfelt H., Nataro J., Puntervoll P. Heat-stable enterotoxin of enterotoxigenic Escherichia coli as a vaccine target. Infect. Immun. 2010, 78:1824-1831.
9. Turner S.M., Scott-Tucker A., Cooper L.M., Henderson I.R. Weapons of mass destruction: virulence factors of the global killer enterotoxigenic Escherichia coli. FEMS Microbiol. Lett. 2006, 263:10-20.