Targeted ablation of the histidine-rich Ca2+-binding protein (HRC) gene is associated with abnormal SR Ca2+-cycling and severe pathology under pressure-overload stress

Basic Research in Cardiology

Volumn 108, Issue 3, 2013, Pages

  Park, Chang Sik ^a   Chen, Shan ^b   Lee, Hoyong ^a   Cha, Hyeseon ^a   Oh, Jae Gyun ^a   Hong, Sunghee ^a   Han, Peidong ^b   Ginsburg, Kenneth S ^c   Jin, Sora ^a   Park, Inju ^a   Singh, Vivek P ^b   Wang, Hong Sheng ^b   Franzini Armstrong, Clara ^d   Park, Woo Jin ^a   Bers, Donald M ^c   Kranias, Evangelia G ^b,e   Cho, Chunghee ^a   Kim, Do Han ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e Academy of Athens Biomedical Research Foundation   (Greece)

Author keywords

Calcium cycling; Fibrosis; Heart failure; Hypertrophy; Pulmonary edema; Sarcoplasmic reticulum

Indexed keywords

CALCIUM BINDING PROTEIN; CALCIUM ION; HISTIDINE RICH CALCIUM BINDING PROTEIN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE OVERLOAD; LUNG EDEMA; MALE; MOUSE; NONHUMAN; SARCOPLASMIC RETICULUM; SURVIVAL RATE;

EID: 84875491683     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-013-0344-2     Document Type: Article

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