Changes in enterococcal populations and related antibiotic resistance along a medical center-wastewater treatment plant-river Continuum

Applied and Environmental Microbiology

Volumn 79, Issue 7, 2013, Pages 2428-2434

  Leclercq, Roland ^a   Oberlé, Kenny ^b,c   Galopin, Sébastien ^a   Cattoir, Vincent ^a   Budzinski, Héléne ^d   Petit, Fabienne ^b,c  

^a UNIVERSITÉ DE CAEN   (France)

^b UNIVERSITÉ DE ROUEN   (France)

^c CNRS   (France)

^d UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC CONCENTRATION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SUSCEPTIBILITIES; AQUATIC ENVIRONMENTS; CULTURE-BASED METHODS; GASTROINTESTINAL TRACT; MACROLIDE RESISTANCE; MULTILOCUS SEQUENCE TYPING;

BACILLI; GENES; HOSPITALS; METABOLITES; POPULATION STATISTICS; SEWAGE PUMPING PLANTS; WATER POLLUTION; WATER TREATMENT PLANTS;

ANTIBIOTICS;

ANTIINFECTIVE AGENT; BACTERIAL PROTEIN;

ANTIBIOTIC RESISTANCE; AQUATIC ENVIRONMENT; BACTERIOLOGY; DIGESTIVE SYSTEM DISORDER; ECOLOGICAL IMPACT; EFFLUENT; EXCRETION; FECAL COLIFORM; HOSPITAL SECTOR; RIVER POLLUTION; SEWAGE TREATMENT; SUBPOPULATION;

ANTIBIOTIC RESISTANCE; ARTICLE; CLASSIFICATION; DRUG EFFECT; ENTEROCOCCUS; FRANCE; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTILOCUS SEQUENCE TYPING; POLYMERASE CHAIN REACTION; RIVER; UNIVERSITY HOSPITAL; WASTE WATER;

ACADEMIC MEDICAL CENTERS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; ENTEROCOCCUS; FRANCE; HUMANS; MICROBIAL SENSITIVITY TESTS; MULTILOCUS SEQUENCE TYPING; POLYMERASE CHAIN REACTION; RIVERS; WASTE WATER;

FRANCE;

ENTEROCOCCUS; ENTEROCOCCUS FAECIUM;

EID: 84875488505     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.03586-12     Document Type: Article

References (40)

1. Arias CA, Murray BE. 2012. The rise of the Enterococcus: beyond vancomycin resistance. Nat. Rev. Microbiol. 10:266-278.
2. Homan WL, Tribe D, Poznanski S, Li M, Hogg G, Spalburg E, Van Embden JD, Willems RJ. 2002. Multilocus sequence typing scheme for Enterococcus faecium. J. Clin. Microbiol. 40:1963-1971.
3. Willems RJ, Top J, van Santen M, Robinson DA, Coque TM, Baquero F, Grundmann H, Bonten MJ. 2005. Global spread of vancomycinresistant Enterococcus faecium from distinct nosocomial genetic complex. Emerg. Infect. Dis. 11:821-828.
4. Top J, Willems R, Bonten M. 2008. Emergence of CC17 Enterococcus faecium: from commensal to hospital-adapted pathogen. FEMS Immunol. Med. Microbiol. 52:297-308.
5. van Schaik W, Top J, Riley DR, Boekhorst J, Vrijenhoek JE, Schapendonk CM, Hendrickx AP, Nijman IJ, Bonten MJ, Tettelin H, Willems RJ. 2010. Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island. BMC Genomics 11:239. doi:10.1186/1471-2164-11-239.
6. Kümmerer K. 2003. Significance of antibiotics in the environment. J. Antimicrob. Chemother. 52:5-7.
7. Chambers HF. 2001. Antimicrobial agents: protein synthesis inhibitors and miscellaneous antibacterial agents, p 1239-1271. In Brunton LL, Chabner BA, Knollmann BC (ed), Goodman and Gilman's the pharmacological basis of therapeutics. McGraw-Hill, New York, NY.
8. Zuccato E, Castiglioni S, Bagnati R, Melis M, Fanelli R. 2010. Source, occurrence and fate of antibiotics in the Italian aquatic environment. J. Hazard. Mater. 179:1042-1048.
9. Salyers AA, Gupta A, Wang Y. 2004. Human intestinal bacteria as reservoirs for antibiotic resistance genes. Trends Microbiol. 12:412-416.
10. Reinthaler FF, Posch J, Feierl G, Wüst G, Haas D, Ruckenbauer G, Mascher F, Marth E. 2003. Antibiotic resistance of E. coli in sewage and sludge. Water Res. 37:1685-1690.
11. Cristian T, Schneider RJ, Fäber H, Skutlarek D, Meyer MT, Goldbach HE. 2003. Determination of antibiotic residues in manure, soil, and surface waters. Acta Hydrochim. Hydrobiol. 31:36-44.
12. Mote BL, Turner JW, Lipp EK. 2012. Persistence and growth of the fecal indicator bacteria enterococci in detritus and natural estuarine plankton communities. Appl. Environ. Microbiol. 78:2569-2577.
13. Signoretto C, Burlacchini G, Pruzzo C, Canepari P. 2005. Persistence of Enterococcus faecalis in aquatic environments via surface interactions with copepods. Appl. Environ. Microbiol. 71:2756-2761.
14. Oberlé K, Capdeville MJ, Berthe T, Budzinski H, Petit F. 2012. Evidence for a complex relationship between antibiotics and antibiotic-resistant Escherichia coli: from medical center patients to a receiving environment. Environ. Sci. Technol. 46:1859-1868.
15. Dutka-Malen S, Evers S, Courvalin P. 1995. Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. J. Clin. Microbiol. 33:24-27.
16. Poyart C, Quesnes G, Trieu-Cuot P. 2000. Sequencing the gene encoding manganese-dependent superoxide dismutase for rapid species identification of enterococci. J. Clin. Microbiol. 38:415-418.
17. Angot P, Vergnaud M, Auzou M, Leclercq R. 2000. Macrolide resistance phenotypes and genotypes in French clinical isolates of Streptococcus pneumoniae. Observatoire de Normandie du Pneumocoque. Eur. J. Clin. Microbiol. Infect. Dis. 19:755-758.
18. Petsaris O, Miszczak F, Gicquel-Bruneau M, Perrin-Guyomard A, Humbert F, Sanders P, Leclercq R. 2005. Combined antimicrobial resistance in Enterococcus faecium isolated from chickens. Appl. Environ. Microbiol. 71:2796-2799.
19. Aminov RI, Garrigues-Jeanjean N, Mackie RI. 2001. Molecular ecology of tetracycline resistance: development and validation of primers for detection of tetracycline resistance genes encoding ribosomal protection proteins. Appl. Environ. Microbiol. 67:22-32.
20. Feil EJ, Li BC, Aanensen DM, Hanage WP, Spratt BG. 2004. eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J. Bacteriol. 186: 1518-1530.
21. Längin A, Alexy R, König A, Kümmerer K. 2009. Deactivation and transformation products in biodegradability testing of beta-lactams amoxicillin and piperacillin. Chemosphere 75:347-354.
22. WHO. 2004. WHO guidelines for drinking-water quality, p 515. Recommendations, 3rd ed, vol 1. World Health Organization, Geneva, Switzerland.
23. Pan X, Jones KD. 2012. Seasonal variation of fecal indicator bacteria in storm events within the US stormwater database. Water Sci. Technol. 65:1076-1080.
24. Bonjoch X, García-Aljaro C, Blanch AR. 2011. Persistence and diversity of faecal coliform and enterococci populations in faecally polluted waters. J. Appl. Microbiol. 111:209-215.
25. Lanthier M, Scott A, Lapen DR, Zhang Y, Topp E. 2010. Frequency of virulence genes and antibiotic resistances in Enterococcus spp. isolates from wastewater and feces of domesticated mammals and birds, and wildlife. Can. J. Microbiol. 56:715-729.
26. Lanthier M, Scott A, Zhang Y, Cloutier M, Durie D, Henderson VC, Wilkes G, Lapen DR, Topp E. 2011. Distribution of selected virulence genes and antibiotic resistance in Enterococcus species isolated from the South Nation River drainage basin, Ontario, Canada. J. Appl. Microbiol. 110:407-421.
27. Luczkiewicz A, Jankowska K, Fudala-Ksia̧z̈ek S, Olańczuk-Neyman K. 2010. Antimicrobial resistance of fecal indicators in municipal wastewater treatment plant. Water Res. 44:5089-5097.
28. Thevenon F, Regier N, Benagli C, Tonolla M, Adatte T, Wildi W, Poté J. 2012. Characterization of fecal indicator bacteria in sediments cores from the largest freshwater lake of Western Europe (Lake Geneva, Switzerland). Ecotoxicol. Environ. Saf. 78:50-56.
29. Varon E. 2009. Quinolones and Gram-positive bacteria, p 243-259. In Courvalin P, Leclercq R, Rice L (ed), Antibiogram. ASM Press, Washington, DC.
30. Liu A, Fong A, Becket E, Yuan J, Tamae C, Medrano L, Maiz M, Wahba C, Lee C, Lee K, Tran KP, Yang H, Hoffman RM, Salih A, Miller JH. 2011. Selective advantage of resistant strains at trace levels of antibiotics: a simple and ultrasensitive color test for detection of antibiotics and genotoxic agents. Antimicrob. Agents Chemother. 55:1204-1210.
31. Baquero F, Negri MC, Morosini MI, Blazquez J. 1998. Antibioticselective environments. Clin. Infect. Dis. 27:S5-S11.
32. Gullberg E, Cao S, Berg OG, Ilbäck C, Sandegren L, Hughes D, Andersson DI. 2011. Selection of resistant bacteria at very low antibiotic concentrations. PLoS Pathog. 7:e1002158. doi:10.1371/journal.ppat .1002158.
33. Xu WH, Zhang G, Wai OWH, Zou SC, Li XD. 2009. Transport and adsorption of antibiotics by marine sediments in a dynamic environment. J. Soils Sediments 9:364-373. 34. Bourdon N, Fines-Guyon M, Thiolet JM, Maugat S, Coignard B, Leclercq R, Cattoir V. 2011. Changing trends in vancomycin-resistant enterococci in French hospitals, 2001-08. J. Antimicrob. Chemother. 66: 713-721.
34. Bourdon N, Fines-Guyon M, Thiolet JM, Maugat S, Coignard B, Leclercq R, Cattoir V. 2011. Changing trends in vancomycin-resistant enterococci in French hospitals, 2001-08. J. Antimicrob. Chemother. 66: 713-721.
35. Ramsey AM, Zilberberg MD. 2009. Secular trends of hospitalization with vancomycin-resistant enterococcus infection in the United States, 2000-2006. Infect. Control Hosp. Epidemiol. 30:184-186.
36. Morris D, Galvin S, Boyle F, Hickey P, Mulligan M, Cormican M. 2012. Enterococcus faecium of the vanA genotype in rural drinking water, effluent, and the aqueous environment. Appl. Environ. Microbiol. 78:596-598.
37. Caplin JL, Hanlon GW, Taylor HD. 2008. Presence of vancomycin and ampicillin-resistant Enterococcus faecium of epidemic clonal complex-17 in wastewaters from the south coast of England. Environ. Microbiol. 10: 885-892.
38. Araújo C, Torres C, Silva N, Carneiro C, Gonçalves A, Radhouani H, Correia S, da Costa PM, Paccheco R, Zarazaga M, Ruiz-Larrea F, Poeta P, Igrejas G. 2010. Vancomycin-resistant enterococci from Portuguese wastewater treatment plants. J. Basic Microbiol. 50:605-609.
39. Hegstad K, Mikalsen T, Coque TM, Werner G, Sundsfjord A. 2010. Mobile genetic elements and their contribution to the emergence of antimicrobial resistant Enterococcus faecalis and Enterococcus faecium. Clin. Microbiol. Infect. 16:541-554.
40. Leclercq R. 2002. Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin. Infect. Dis. 34:482-492.