Ultra Performance Liquid Chromatography-Based Metabonomic Study of Therapeutic Effect of the Surface Layer of Poria cocos on Adenine-Induced Chronic Kidney Disease Provides New Insight into Anti-Fibrosis Mechanism

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Zhao, Ying Yong ^a,d   Feng, Ya Long ^a,d   Bai, Xu ^b,d   Tan, Xiao Jie ^b,d   Lin, Rui Chao ^c,d   Mei, Qibing ^b,d  

^a NORTHWEST UNIVERSITY   (China)

^b Waters Technologies Shanghai Ltd   (China)

^c NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CREATININE; HEXANOIC ACID; PORIA COCOS EXTRACT; TETRACOSAHEXANOIC ACID; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFIBROSIS ACTIVITY; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DATA COLLECTION METHOD; DRUG ACTIVITY; DRUG MECHANISM; ENERGY METABOLISM; HISTOPATHOLOGY; MALE; METABOLIC REGULATION; NONHUMAN; PHOSPHOLIPID METABOLISM; PHYTOCHEMISTRY; RAT; RENAL PROTECTION; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ADENINE; ANIMALS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FIBROSIS; MALE; MASS SPECTROMETRY; MEDICINE, CHINESE TRADITIONAL; METABOLOMICS; PORIA; RATS; RATS, SPRAGUE-DAWLEY; RENAL INSUFFICIENCY, CHRONIC; REPRODUCIBILITY OF RESULTS;

PORIA COCOS; RATTUS;

EID: 84875473637     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059617     Document Type: Article

References (40)

1. Nicholson JK, Lindon JC, Holmes E, (1999) "Metabonomics": understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29: 1181-1189.
2. Coen M, Holmes E, Lindon JC, Nicholson JK, (2008) NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chem Res Toxicol 21: 9-27.
3. Van WH, Yuan K, Lu C, Gao P, Wang J, et al. (2009) Systems biology guided by Chinese medicine reveals new markers for sub-typing rheumatoid arthritis patients. J Clin Rheumatol 15: 330-337.
4. Xiang Z, Wang XQ, Cai XJ, Zeng S, (2011) Metabolomics study on quality control and discrimination of three Curcuma species based on gas chromatograph-mass spectrometry. Phytochem Anal 22: 411-418.
5. Yang B, Zhang A, Sun H, Dong W, Yan G, et al. (2012) Metabolomic study of insomnia and intervention effects of Suanzaoren decoction using ultra-performance liquid-chromatography/electrospray-ionization synapt high-definition mass spectrometry. J Pharmaceut Biomed 58: 113-124.
6. Lao YM, Jiang JG, Yan L, (2009) Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine. Brit J Pharmacol 157: 1128-1141.
7. Roux A, Lison D, Junot C, Heilier JF, (2011) Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review. Clin Biochem 44: 119-135.
8. Wilson ID, Nicholson JK, Castro-Perez J, Granger JH, Johnson KA, et al. (2005) High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies. J Proteome Res 4: 591-598.
9. Wrona M, Mauriala T, Bateman KP, Mortishire-Smith RJ, O'Connor D, (2005) 'All-in-One' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching. Rapid Commun Mass Spectrom 19: 2597-2602.
10. Zhao YY, Cheng XL, Wei F, Bai X, Tan XJ, et al. (2013) Intrarenal metabolomic investigation of chronic kidney disease and its TGF-β1 mechanism in induced-adenine rats using UPLC Q-TOF/HSMS/MSE. J Proteome Res 12: 692-703.
11. Zhao YY, Zhang L, Long FY, Cheng XL, Bai X, et al. (2013) UPLC-Q-TOF/HSMS/MSE-based metabonomics for adenine-induced changes in metabolic profiles of rat faeces and intervention effects of ergosta-4,6,8(14), 22-tetraen-3-one. Chem Biol Interact 301: 31-38.
12. Wyngaarden JB, Dunn JT, (1957) 8-hydroxyadenine as the metabolic intermediate in the oxidation of adenine to 2, 8-dihydroxyadenine by xanthine oxidase. Arch Biochem Biophys 70: 150-156.
13. Yokozawa T, Zheng PD, Oura H, Koizumi F, (1986) Animal model of adenine-induced chronic renal failure in rats. Nephron 44: 230-234.
14. Zhao YY, Cheng XL, Wei F, Bai X, Lin RC, (2012) Effect of ergosta-4,6,8(14), 22-tetraen-3-one (ergone) on adenine-induced chronic renal failure rat: A serum metabonomics study based on ultra performance liquid chromatography/high-sensitivity mass spectrometry coupled with MassLynx i-FIT algorithm. Clin Chim Acta 413: 1438-1445.
15. Zhao YY, Cheng XL, Wei F, Bai X, Lin RC, (2012) Application of faecal metabonomics on an experimental model of tubulointerstitial fibrosis by ultra performance liquid chromatography/high-sensitivity mass spectrometry with MSE data collection technique. Biomarkers 17: 721-729.
16. Zhao YY, Cheng XL, Wei F, Xiao XY, Sun WJ, et al. (2012) Serum metabonomics study of adenine-induced chronic renal failure rat by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Biomarkers 17: 48-55.
17. Zhao YY, Liu J, Cheng XL, Bai X, Lin RC, (2012) Urinary metabonomics study on biochemical changes in an experimental model of chronic renal failure by adenine based on UPLC Q-TOF/MS. Clin Chim Acta 413: 642-649.
18. Zhao YY, Shen X, Cheng XL, Wei F, Bai X, et al. (2012) Urinary metabonomics study on the protective effects of ergosta-4,6,8(14), 22-tetraen-3-one on chronic renal failure in rats using UPLC Q-TOF/MS and a novel MSE data collection technique. Process Biochem 47: 1980-1987.
19. Lee KY, Jeon YJ, (2003) Polysaccharide isolated from Poria cocos sclerotium induces NF-jB/Rel activation and iNOS expression in murine macrophages. Int Immunopharmacol 3: 1353-1362.
20. Pharmacopoeia of People's Republic of China (Part I) (2010) Beijing: China Medical Science Press. 224-225 p.
21. Ríos JL, (2011) Chemical constituents and pharmacological properties of Poria cocos. Planta Med 77: 681-691.
22. Sekiya N, Goto H, Shimada Y, Endo Y, Sakakibara I, et al. (2003) Inhibitory effects of triterpenes isolated from hoelen on free radical-induced lysis of red blood cells. Phytother Res 17: 160-162.
23. Chen YY, Chang HM, (2004) Antiproliferative and differentiating effects of polysaccharide fraction from fu-ling (Poria cocos) on human leukemic U937 and HL-60 cells. Food Chem Toxicol 42: 759-769.
24. Wang Y, Zhang M, Ruan D, Shashkov AS, Kilcoyne M, et al. (2004) Chemical components and molecular mass of six polysaccharides isolated from the sclerotium of Poria cocos. Carbohyd Res 339: 327-334.
25. Akihisa T, Nakamura Y, Tokuda H, Uchiyama E, Suzuki T, et al. (2007) Triterpene acids from Poria cocos and their anti-tumor-promoting effects. J Nat Prod 70: 948-953.
26. Zheng Y, Yang XW, (2008) Two new lanostane triterpenoids from Poria cocos. J Asian Nat Prod Res 10: 289-292.
27. Zheng Y, Yang XW, (2008) Poriacosones A and B: two new lanostane triterpenoids from Poria cocos. J Asian Nat Prod Res 10: 640-646.
28. Tai T, Akahori A, Shingu T, (1993) Triterpenes of Poria cocos. Phytochemistry 32: 1239-1244.
29. Tai T, Shingu T, Kikuchi T, Tezuka Y, Akahor A, (1995) Triterpenes from the surface layer of Poria cocos. Phytochemistry 39: 1165-1169.
30. Yang CH, Zhang SF, Liu WY, Zhang ZJ, Liu JH, (2009) Two new triterpenes from the surface layer of Poria cocos. Helv Chim Acta 92: 660-667.
31. Zhao YY, Feng YL. Du X, Xi ZH. Cheng XL, et al. (2012) Diuretic activity of the ethanol and aqueous extracts of the surface layer of Poria cocos in rat. J Ethnopharmacol 144: 775-778.
32. Otvos JD, Jeyarajah EJ, Bennett DW, (1991) Quantification of plasma lipoproteins by proton nuclear magnetic resonance spectroscopy. Clin Chem 37: 377-386.
33. Ilcol YO, Dilek K, Yurtkuran MH, Ulus I, (2002) Changes of plasma free choline and choline-containing compounds' concentrations and choline loss during hemodialysis in ESRD patients. Clin biochem 35: 233-239.
34. Ilcol YO, Dönmez O, Yavuz M, Dilek K, Yurtkuran M, et al. (2002) Free choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults. Clin biochem 35: 307-313.
35. Maldonado P, Barrera D, Rivero I, Mata R, Medina CO, et al. (2003b) Antioxidant S-allylcysteine prevents gentamicin-induced oxidative stress and renal damage. Free Radical Biol Med 35: 317-324.
36. Maldonado P, Barrera D, Medina CO, Hernandez PR, Ibarra RM, et al. (2003) Aged garlic extract attenuates gentamicin induced renal damage and oxidative stress in rats. Life Sci 73: 2543-2556.
37. Rahman A, Ahmed S, Vasenwala SM, Athar M, (2003) Glyceryl trinitrate, a nitric oxide donor, abrogates ferric nitrilotriacetate-induced oxidative stress and renal damage. Arch Biochem Biophys 418: 71-79.
38. Miyata T, Kurokawa K, van Ypersele de SC, (2000) Relevance of oxidative and carbonyl stress to long-term uremic complications. Kidney Int 76: S120-S125.
39. Shidfar F, Keshavarz A, Hosseyni S, Ameri A, Yarahmadi S, (2008) Effects of omega-3 fatty acid supplements on serum lipids, apolipoproteins and ma-londialdehyde in type 2 diabetes patients. East Mediterran Health J 14: 305-315.
40. Bassa BV, Noh JW, Ganji SH, Shin MK, Roh DD, et al. (2007) Lysophosphatidylcholine stimulates EGF receptor activation and mesangial cell proliferation: regulatory role of Src and PKC. Biochim Biophys Acta 1771: 1364-1371.