Naevus marginatus revisited: A combined organoid and nonorganoid epidermal naevus caused by HRAS mutation

British Journal of Dermatology

Volumn 168, Issue 4, 2013, Pages 892-894

  Groesser, L ^a   Vogt, T ^b   Happle, R ^c   Herschberger, E ^a   Mickler, M ^a   Landthaler, M ^a   Hafner, C ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

H RAS PROTEIN; K RAS PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

CELL DIFFERENTIATION; CELL PROLIFERATION; CLINICAL ASSESSMENT; CODON; HISTOPATHOLOGY; HUMAN; KERATINOCYTE; KERATINOCYTIC EPIDERMAL NEVUS; LETTER; NAEVUS MARGINATUS; NEVUS; PRIORITY JOURNAL; SEBACEOUS NEVUS; SKIN BIOPSY; VERRUCA VULGARIS;

HUMANS; MOSAICISM; NEVUS, EPITHELIOID AND SPINDLE CELL; ORGANOIDS; PROTO-ONCOGENE PROTEINS P21(RAS); SKIN NEOPLASMS;

EID: 84875462449     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/bjd.12085     Document Type: Letter

References (10)

1. Happle R,. The group of epidermal nevus syndromes Part I. Well defined phenotypes. J Am Acad Dermatol 2010; 63: 1-22; quiz 23-4.
2. Hafner C, Landthaler M, Happle R, Vogt T,. Nevus marginatus: a distinct type of epidermal nevus or merely a variant of nevus sebaceus? Dermatology 2008; 216: 236-8.
3. Happle R,. Mosaicism in human skin. Understanding the patterns and mechanisms. Arch Dermatol 1993; 129: 1460-70.
4. Hafner C, van Oers JM, Vogt T, et al. Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi. J Clin Invest 2006; 116: 2201-7.
5. Hafner C, Lõpez-Knowles E, Luis NM, et al. Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern. Proc Natl Acad Sci USA 2007; 104: 13450-4.
6. Hafner C, Toll A, Gantner S, et al. Keratinocytic epidermal nevi are associated with mosaic RAS mutations. J Med Genet 2012; 49: 249-53.
7. Groesser L, Herschberger E, Ruetten A, et al. Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome. Nat Genet 2012; 44: 783-7.
8. Sol-Church K, Stabley DL, Demmer LA, et al. Male-to-male transmission of Costello syndrome: G12S HRAS germline mutation inherited from a father with somatic mosaicism. Am J Med Genet A 2009; 149A: 315-21.
9. Hafner C, Toll A, Real FX,. HRAS mutation mosaicism causing urothelial cancer and epidermal nevus. N Engl J Med 2011; 365: 1940-2.
10. Tidyman WE, Rauen KA,. The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation. Curr Opin Genet Dev 2009; 19: 230-6.