Profilin may be a primary airborne sensitizer: A case report

Journal of Investigational Allergology and Clinical Immunology

Volumn 23, Issue 2, 2013, Pages 134-135

  Asero, R ^a   Villalta, D ^b  

^a CLINICA SAN CARLO   (Italy)

^b Dipartimento di Medicina di Laboratorio   (Italy)

Author keywords

Allergens; Pollen allergy; Profilin; Respiratory allergy

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; POLLEN ANTIGEN; PROFILIN;

ADULT; AIRBORNE PARTICLE; ALLERGY TEST; ANTIGEN ANTIBODY COMPLEX; CASE REPORT; CONJUNCTIVITIS; FEMALE; GENETIC PREDISPOSITION; HUMAN; IMMUNOASSAY; IMMUNOREACTIVITY; INTRACUTANEOUS TEST; NOTE; POLLEN ALLERGY; PRICK TEST; PRURITUS; RHINITIS; SENSITIZATION;

ADULT; AIR POLLUTANTS; ALLERGENS; ANTIGENS, PLANT; ENVIRONMENTAL ILLNESS; FEMALE; HUMANS; IMMUNOGLOBULIN E; PROFILINS;

EID: 84875448847     PISSN: 10189068     EISSN: 16980808     Source Type: Journal    
DOI: None     Document Type: Note

References (9)

1. Valenta R, Duchene M, Pettenburger K, Sillaber C, Valent P, Bettelheim P, Breitenbach M, Rumpold H, Kraft D, Scheiner O. Identifi cation of profi lin as a novel pollen allergen; IgE autoreactivity in sensitized individuals. Science. 1991;253:557-60.
2. Valenta R, Duchene M, Ebner C, Valent P, Sillaber C, Deviller P, Ferreira F, Tejkl M, Edelmann H, Kraft D. Profi lins constitute a novel family of functional plant pan-allergens. J Exp Med. 1992;175:377-85.
3. Ebner C, Hirschwehr R, Bauer L, Breiteneder H, Valenta R, Ebner H, Kraft D, Scheiner O. Identifi cation of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profi lin). J Allergy Clin Immunol. 1995;95:962-69.
4. Asero R, Monsalve R, Barber D. Profi lin sensitization detected in the offi ce by skin prick test: a study of prevalence and clinical relevance of profi lin as a plant food allergen. Clin Exp Allergy. 2008; 38: 1033-7.
5. Asero R, Jimeno L, Barber D. Preliminary results of a SPT study about prevalence and clinical relevance of hypersensitivity to pollen pan-allergens (polcalcin and profi lin). J Invest Allergol Clin Immunol. 2010; 20: 35-8.
6. Ruiz-Garcia M, Garcia del Potre M, Fernandez Nieto M, Barber D, Jimeno-Nogales L, Sastre J. Profi lin: a relevant aeroallergen. J Allergy Clin Immunol. 2011; 128: 416-8.
7. Nunez R, Carballada F, Lombardero M, Jimeno L, Boquete M. Profi lin as an aeroallergen by means of conjunctival allergen challenge with purifi ed date palm profi lin. Int Arch Allergy Immunol. 2012; 158: 115-9.
8. Asero R, Mistrello G, Roncarolo D, Amato S, Zanoni D, Barocci F, Caldironi G. Detection of clinical markers of sensitization to profi lin in patients allergic to plant-derived foods. J Allergy Clin Immunol. 2003; 112: 427-32.
9. Asero R, Mistrello G, Roncarolo D, Amato S. Parietaria profi lin shows only limited cross-reactivity with birch and grass profi lins. Int Arch Allergy Immunol. 2004; 133: 121-4.