메뉴 건너뛰기




Volumn 108, Issue 5, 2013, Pages 1042-1051

Biology of primary breast cancer in older women treated by surgery: With correlation with long-term clinical outcome and comparison with their younger counterparts

Author keywords

biology; breast cancer; clinical outcome; older women

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CYTOKERATIN 14; CYTOKERATIN 17; CYTOKERATIN 18; CYTOKERATIN 19; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; ESTROGEN RECEPTOR; KI 67 ANTIGEN; MUCIN 1; PROGESTERONE RECEPTOR; PROTEIN BCL 2; PROTEIN KINASE LKB1; PROTEIN MDM2; PROTEIN MDMX; PROTEIN P53; VASCULOTROPIN RECEPTOR;

EID: 84875425312     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.601     Document Type: Article
Times cited : (58)

References (53)
  • 1
    • 22244449596 scopus 로고    scopus 로고
    • High-throughput protein expression analysis usingtissue microarray technology of a large well-characterised series identifiesbiologically distinct classes of breast cancer confirming recent cDNAexpression analyses
    • Abd El-Rehim D, Ball G, Pinder S, Rakha E, Paish C, Robertson J, Macmillan D, Blamey R, Ellis I (2005) High-throughput protein expression analysis usingtissue microarray technology of a large well-characterised series identifiesbiologically distinct classes of breast cancer confirming recent cDNAexpression analyses. Int J Cancer 116: 340-350.
    • (2005) Int J Cancer , vol.116 , pp. 340-350
    • Abd El-Rehim, D.1    Ball, G.2    Pinder, S.3    Rakha, E.4    Paish, C.5    Robertson, J.6    MacMillan, D.7    Blamey, R.8    Ellis, I.9
  • 3
    • 0026020406 scopus 로고
    • A 10-yearexperience of tamoxifen as primary-treatment of breast-cancer in 100elderly and frail patients
    • Akhtar S, Allan S, Rodger A, Chetty U, Smyth J, Leonard R (1991) A 10-yearexperience of tamoxifen as primary-treatment of breast-cancer in 100elderly and frail patients. Eur J Surg Oncol 17: 30-35.
    • (1991) Eur J Surg Oncol , vol.17 , pp. 30-35
    • Akhtar, S.1    Allan, S.2    Rodger, A.3    Chetty, U.4    Smyth, J.5    Leonard, R.6
  • 4
    • 79958277115 scopus 로고    scopus 로고
    • MIB1/Ki-67 labelling index can classify grade 2 breast cancer into twoclinically distinct subgroups
    • Aleskandarany M, Rakha E, Macmillan R, Powe D, Ellis I, Green A (2011) MIB1/Ki-67 labelling index can classify grade 2 breast cancer into twoclinically distinct subgroups. Breast Cancer Res Treat 127 (3) : 591-599.
    • (2011) Breast Cancer Res Treat , vol.127 , Issue.3 , pp. 591-599
    • Aleskandarany, M.1    Rakha, E.2    MacMillan, R.3    Powe, D.4    Ellis, I.5    Green, A.6
  • 5
    • 0006861761 scopus 로고
    • Tamoxifen as primary treatment of breast cancer in elderly or frailpatients: A practical management
    • Allan SG, Rodger A, Smyth JF, Leonard RC, Chetty U, Forrest AP (1985) Tamoxifen as primary treatment of breast cancer in elderly or frailpatients: a practical management. Br Med J (Clin Res Ed) 290 (6465) : 358.
    • (1985) Br Med J (Clin Res Ed) , vol.290 , Issue.6465 , pp. 358
    • Allan, S.G.1    Rodger, A.2    Smyth, J.F.3    Leonard, R.C.4    Chetty, U.5    Forrest, A.P.6
  • 8
    • 45949097829 scopus 로고    scopus 로고
    • Meta-analysis confirmsBCL2 is an independent prognostic marker in breast cancer
    • Callagy G, Webber M, Pharoah P, Caldas C (2008) Meta-analysis confirmsBCL2 is an independent prognostic marker in breast cancer. BiomedCentral Cancer 8: 153.
    • (2008) BiomedCentral Cancer , vol.8 , pp. 153
    • Callagy, G.1    Webber, M.2    Pharoah, P.3    Caldas, C.4
  • 10
    • 0034535382 scopus 로고    scopus 로고
    • Validation of tissue microarraytechnology in breast carcinoma
    • Camp R, Charette L, Rimm D (2000) Validation of tissue microarraytechnology in breast carcinoma. Lab Invest 80: 1943-1949.
    • (2000) Lab Invest , vol.80 , pp. 1943-1949
    • Camp, R.1    Charette, L.2    Rimm, D.3
  • 11
    • 8444244786 scopus 로고    scopus 로고
    • X-tile: A new bio-informatics toolfor biomarker assessment and outcome-based cut-point optimization
    • Camp R, Dolled-Filhart M, Rimm D (2004) X-tile: a new bio-informatics toolfor biomarker assessment and outcome-based cut-point optimization. ClinCancer Res 10 (21) : 7252-7259.
    • (2004) ClinCancer Res , vol.10 , Issue.21 , pp. 7252-7259
    • Camp, R.1    Dolled-Filhart, M.2    Rimm, D.3
  • 12
    • 48749129371 scopus 로고    scopus 로고
    • Pathological features of primary breast cancer in the elderly basedon needle core biopsies-A large series from a single centre
    • Cheung K, Wong A, Parker H, Li V, Winterbottom L, Morgan D, Ellis I (2008) Pathological features of primary breast cancer in the elderly basedon needle core biopsies-A large series from a single centre. Crit Rev OncolHematol 67: 263-267.
    • (2008) Crit Rev OncolHematol , vol.67 , pp. 263-267
    • Cheung, K.1    Wong, A.2    Parker, H.3    Li, V.4    Winterbottom, L.5    Morgan, D.6    Ellis, I.7
  • 13
    • 0029926851 scopus 로고    scopus 로고
    • Tamoxifen as primarytreatment of breast cancer in elderly patients
    • Ciatto S, Cirillo A, Confortini M, Cardillo C (1996) Tamoxifen as primarytreatment of breast cancer in elderly patients. Neoplasma 43-45.
    • (1996) Neoplasma , pp. 43-45
    • Ciatto, S.1    Cirillo, A.2    Confortini, M.3    Cardillo, C.4
  • 14
    • 0037334579 scopus 로고    scopus 로고
    • Primary breast cancerin elderly women biological profile and relation with clinical outcome
    • Daidone M, Coradini D, Martelli G, Veneroni S (2003) Primary breast cancerin elderly women: biological profile and relation with clinical outcome.Crit Rev Oncol Hematol 45: 313-325.
    • (2003) Crit Rev Oncol Hematol , vol.45 , pp. 313-325
    • Daidone, M.1    Coradini, D.2    Martelli, G.3    Veneroni, S.4
  • 16
    • 0034607235 scopus 로고    scopus 로고
    • Tumor characteristics and clinicaloutcome of elderly women with breast cancer
    • Diab S, Elledge R, Clark G (2000) Tumor characteristics and clinicaloutcome of elderly women with breast cancer. J Natl Cancer Inst 92 (7) :550-556.
    • (2000) J Natl Cancer Inst , vol.92 , Issue.7 , pp. 550-556
    • Diab, S.1    Elledge, R.2    Clark, G.3
  • 18
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer I. Thevalue of histological grade in breast cancer: Experience from a large studywith long-term follow-up
    • Elston C, Ellis I (1991) Pathological prognostic factors in breast cancer. I. Thevalue of histological grade in breast cancer: experience from a large studywith long-term follow-up. Histopathology 19 (5) : 403-410.
    • (1991) Histopathology , vol.19 , Issue.5 , pp. 403-410
    • Elston, C.1    Ellis, I.2
  • 20
    • 0033143455 scopus 로고    scopus 로고
    • A comprehensiveprognostic index to predict survival based on multiple comorbidities: Afocus on breast cancer
    • Fleming S, Rastogi A, Dmitrienko A, Johnson K (1999) A comprehensiveprognostic index to predict survival based on multiple comorbidities: afocus on breast cancer. Med Care 37 (6) : 601-614.
    • (1999) Med Care , vol.37 , Issue.6 , pp. 601-614
    • Fleming, S.1    Rastogi, A.2    Dmitrienko, A.3    Johnson, K.4
  • 26
    • 70350655869 scopus 로고    scopus 로고
    • Prognostic significance of basalmarkers in triple-negative breast cancers
    • Kim J, Hwang T, Kang S, Lee S, Bae Y (2009) Prognostic significance of basalmarkers in triple-negative breast cancers. J Breast Cancer 4-13.
    • (2009) J Breast Cancer , pp. 4-13
    • Kim, J.1    Hwang, T.2    Kang, S.3    Lee, S.4    Bae, Y.5
  • 27
    • 46849093173 scopus 로고    scopus 로고
    • Prognostic significance of HER2 gene amplification according to stage ofbreast cancer
    • Kim Y, Won Y, Park K, Song B, Kim J, Oh S, Jeon H, Jung S, Park W (2008) Prognostic significance of HER2 gene amplification according to stage ofbreast cancer. J Korean Med Sci 23 (3) : 414-420
    • (2008) J Korean Med Sci , vol.23 , Issue.3 , pp. 414-420
    • Kim, Y.1    Won, Y.2    Park, K.3    Song, B.4    Kim, J.5    Oh, S.6    Jeon, H.7    Jung, S.8    Park, W.9
  • 28
    • 0035879210 scopus 로고    scopus 로고
    • Value ofepidermal growth factor receptor, HER2, p53, and steroid receptors inpredicting the efficacy of tamoxifen in high-risk postmenopausal breastcancer patients
    • Knoop A, Bentzen S, Nielsen M, Rasmussen B, Rose C (2001) Value ofepidermal growth factor receptor, HER2, p53, and steroid receptors inpredicting the efficacy of tamoxifen in high-risk postmenopausal breastcancer patients. J Clin Oncol 19 (14) : 3376-3384.
    • (2001) J Clin Oncol , vol.19 , Issue.14 , pp. 3376-3384
    • Knoop, A.1    Bentzen, S.2    Nielsen, M.3    Rasmussen Rose B, C.4
  • 29
    • 79954526769 scopus 로고    scopus 로고
    • Clinicopathological feature andrecurrence pattern of triple negative breast cancer
    • Lee K, Kim J, Jung J, Park J, Park H (2010) Clinicopathological feature andrecurrence pattern of triple negative breast cancer. J Korean Surg Soc 14-19.
    • (2010) J Korean Surg Soc , pp. 14-19
    • Lee, K.1    Kim, J.2    Jung, J.3    Park, J.4    Park, H.5
  • 30
    • 70949085372 scopus 로고    scopus 로고
    • Shorter survival-timesfollowing adjuvant endocrine therapy in oestrogen-and progesteronereceptorpositive breast cancer overexpressing HER2 and/or with anincreased expression of vascular endothelial growth factor
    • Linderholm B, Bergqvist J, Hellborg H, Johansson U, Linderholm M, vonSchoultz E, Elmberger G, Skoog L, Bergh J (2009) Shorter survival- timesfollowing adjuvant endocrine therapy in oestrogen-and progesteronereceptorpositive breast cancer overexpressing HER2 and/or with anincreased expression of vascular endothelial growth factor. Med Oncol26 (4) : 480-490.
    • (2009) Med Oncol , vol.26 , Issue.4 , pp. 480-490
    • Linderholm, B.1    Bergqvist, J.2    Hellborg, H.3    Johansson, U.4    Linderholm, M.5    Vonschoultz, E.6    Elmberger, G.7    Skoog, L.8    Bergh, J.9
  • 32
    • 67651244248 scopus 로고    scopus 로고
    • Breast cancer in Chinese elderly women: Pathological andclinical characteristics and factors influencing treatment patterns
    • Ma C, Zhou Q, Nie X, Liu G, Di G, Wu J, Lu J, Yang W, Chen J, Shao Z, Shen K, Shen Z (2009) Breast cancer in Chinese elderly women: pathological andclinical characteristics and factors influencing treatment patterns. Crit RevOncol Hematol 71 (3) : 258-265.
    • (2009) Crit RevOncol Hematol , vol.71 , Issue.3 , pp. 258-265
    • Ma, C.1    Zhou, Q.2    Nie, X.3    Liu, G.4    Di, G.5    Wu, J.6    Lu, J.7    Yang, W.8    Chen, J.9    Shao, Z.10    Shen, K.11    Shen, Z.12
  • 34
    • 33644830699 scopus 로고    scopus 로고
    • Reporting recommendations fortumor marker prognostic studies
    • Diagnostics SSotN-EWGoC
    • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM.Diagnostics SSotN-EWGoC (2005) Reporting recommendations fortumor marker prognostic studies. J Clin Oncol 23 (36) : 9067-9072.
    • (2005) J Clin Oncol , vol.23 , Issue.36 , pp. 9067-9072
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3    Taube, S.E.4    Gion, M.5    Clark, G.M.6
  • 36
    • 34047217206 scopus 로고    scopus 로고
    • Randomizedphase III trial of fludarabine plus cyclophosphamide with or withoutoblimersen sodium (Bcl-2 antisense) in patients with relapsed orrefractory chronic lymphocytic leukemia
    • O'Brien S, Moore JO, Boyd TE, Larratt LM, Skotnicki A, Koziner B, Chanan-Khan AA, Seymour JF, Bociek RG, Pavletic S, Rai KR (2007) Randomizedphase III trial of fludarabine plus cyclophosphamide with or withoutoblimersen sodium (Bcl-2 antisense) in patients with relapsed orrefractory chronic lymphocytic leukemia. J Clin Oncol 25 (9) : 1114-1120.
    • (2007) J Clin Oncol , vol.25 , Issue.9 , pp. 1114-1120
    • O'Brien, S.1    Moore, J.O.2    Boyd, T.E.3    Larratt, L.M.4    Skotnicki, A.5    Koziner, B.6    Chanan-Khan, A.A.7    Seymour, J.F.8    Bociek, R.G.9    Pavletic, S.10    Rai, K.R.11
  • 37
    • 33645124171 scopus 로고    scopus 로고
    • Office for National Statistics HerMajesty's stationary
    • office: London Office for National Statistics (2006) Cancer Statistics Registration. HerMajesty's stationary office London.
    • (2006) Cancer Statistics Registration
  • 39
    • 25144504517 scopus 로고    scopus 로고
    • Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breastcancer
    • Rakha E, Boyce R, Abd El-Rehim D, Kurien T, Green A, Paish E, Robertson J, Ellis I (2005) Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breastcancer. Mod Pathol 18: 1295-1304.
    • (2005) Mod Pathol , vol.18 , pp. 1295-1304
    • Rakha, E.1    Boyce, R.2    Abd El-Rehim, D.3    Kurien, T.4    Green, A.5    Paish, E.6    Robertson, J.7    Ellis, I.8
  • 40
    • 44649095619 scopus 로고    scopus 로고
    • Expression of BRCAI protein in breast cancer and its prognosticsignificance
    • Rakha E, El-Sheikh S, Kandil M, El-Sayed M, Green A, Ellis I (2008) Expression of BRCAI protein in breast cancer and its prognosticsignificance. Hum Pathol 39 (6) : 857-865.
    • (2008) Hum Pathol , vol.39 , Issue.6 , pp. 857-865
    • Rakha, E.1    El-Sheikh, S.2    Kandil, M.3    El-Sayed, M.4    Green, A.5    Ellis, I.6
  • 45
  • 46
    • 84875412870 scopus 로고    scopus 로고
    • HER2 positive primary breastcancer in older women: Clinical significance and therapeutic challenge
    • Williams SI, Rogers CE (eds) Chapter 5 NovaPublishers: New York
    • Syed B, Leonard R, Ellis I, Cheung K (2011b) HER2 positive primary breastcancer in older women: clinical significance and therapeutic challenge.In HER2 and Cancer: Mechanism, Testing and Targeted Therapy, Williams SI, Rogers CE (eds) Vol. 1, Chapter 5pp 123-143. NovaPublishers: New York.
    • (2011) HER 2 and Cancer Mechanism, Testing and Targeted Therapy , vol.1 , pp. 123-143
    • Syed, B.1    Leonard, R.2    Ellis, I.3    Cheung, K.4
  • 47
    • 47549107072 scopus 로고    scopus 로고
    • Triplenegative breast cancer: Molecular profiling and prognostic impact inadjuvant anthracycline-treated patients
    • Tan D, Marchio C, Jones R, Savage K, Smith I, Dowsett M, Reis J (2008) Triplenegative breast cancer: molecular profiling and prognostic impact inadjuvant anthracycline-treated patients. Breast Cancer Res Treat 111 (1) :27-44.
    • (2008) Breast Cancer Res Treat , vol.111 , Issue.1 , pp. 27-44
    • Tan, D.1    Marchio, C.2    Jones, R.3    Savage, K.4    Smith, I.5    Dowsett, M.6    Reis, J.7
  • 49
  • 50
    • 77955643463 scopus 로고    scopus 로고
    • Breast cancer classificationaccording to immunohistochemistry markers: Subtypes and associationwith clinicopathologic variables in a peruvian hospital database
    • Vallejos C, Gómez H, Cruz W, Pinto J, Dyer R, Velarde R, Suazo J, Neciosup S, León M, de la Cruz M, Vigil C (2010) Breast cancer classificationaccording to immunohistochemistry markers: subtypes and associationwith clinicopathologic variables in a peruvian hospital database. ClinBreast Cancer 10 (4) : 294-300.
    • (2010) Clin Breast Cancer , vol.10 , Issue.4 , pp. 294-300
    • Vallejos, C.1    Gómez, H.2    Cruz, W.3    Pinto, J.4    Dyer, R.5    Velarde, R.6    Suazo, J.7    Neciosup, S.8    León, M.9    De La Cruz, M.10    Vigil, C.11
  • 51
    • 34447517882 scopus 로고    scopus 로고
    • The expression pattern of MUC1 (EMA) is related totumour characteristics and clinical outcome of invasive ductal breastcarcinoma
    • van der Vegt B, de Roos M, Peterse J, Patriarca C, Hilkens J, de Bock G, Wesseling J (2007) The expression pattern of MUC1 (EMA) is related totumour characteristics and clinical outcome of invasive ductal breastcarcinoma. Histopathology 51 (3) : 322-335.
    • (2007) Histopathology , vol.51 , Issue.3 , pp. 322-335
    • Van Der Vegt, B.1    De Roos, M.2    Peterse, J.3    Patriarca, C.4    Hilkens, J.5    De Bock, G.6    Wesseling, J.7
  • 52
    • 34548444589 scopus 로고    scopus 로고
    • Adjuvanttrastuzumab in the treatment of her-2-positive early breast cancer: A metaanalysisof published randomized trials
    • Viani G, Afonso S, Stefano E, De Fendi L, Soares F (2007) Adjuvanttrastuzumab in the treatment of her-2-positive early breast cancer: a metaanalysisof published randomized trials. Biomed Central Cancer 7: 153.
    • (2007) Biomed Central Cancer , vol.7 , pp. 153
    • Viani, G.1    Afonso, S.2    Stefano, E.3    De Fendi, L.4    Soares, F.5
  • 53
    • 0035925169 scopus 로고    scopus 로고
    • Effect of age and comorbidity in postmenopausal breast cancer patientsaged 55 years and older
    • Yancik R, Wesley MN, Ries LA, Havlik RJ, Edwards BK, Yates JW (2001) Effect of age and comorbidity in postmenopausal breast cancer patientsaged 55 years and older. J Am Med Assoc 285 (7) : 885-892.
    • (2001) J Am Med Assoc , vol.285 , Issue.7 , pp. 885-892
    • Yancik, R.1    Wesley, M.N.2    Ries, L.A.3    Havlik, R.J.4    Edwards, B.K.5    Yates, J.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.