Effectiveness of sepsis bundle application in cirrhotic patients with septic shock: A single-center experience

Journal of Critical Care

Volumn 28, Issue 2, 2013, Pages 152-157

  Rinaldi, Laura ^a   Ferrari, Elena ^a   Marietta, Marco ^a   Donno, Lara ^a   Trevisan, Davide ^a   Codeluppi, Mauro ^a   Busani, Stefano ^a   Girardis, Massimo ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

ALI; ARDS; Cirrhosis; ICU; Intensive care; MAP; MELD; PaO2 FiO2; SAPS; ScvO2; Sepsis bundles; Septic shock; SOFA; SSC

Indexed keywords

ANTIBIOTIC AGENT; GLUCOSE; HYDROCORTISONE; HYPERTENSIVE AGENT;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; CAUSE OF DEATH; CLINICAL ARTICLE; COHORT ANALYSIS; FEMALE; FLUID RESUSCITATION; GLUCOSE BLOOD LEVEL; HUMAN; INTENSIVE CARE UNIT; LIVER CIRRHOSIS; LOW DRUG DOSE; MALE; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; OXYGEN SATURATION; PLATEAU INSPIRATORY PRESSURE; PRACTICE GUIDELINE; PRESSURE; PROSPECTIVE STUDY; RESUSCITATION; SEPTIC SHOCK; SURVIVAL RATE;

ADULT; CLINICAL PROTOCOLS; FEMALE; GUIDELINE ADHERENCE; HOSPITALS, UNIVERSITY; HUMANS; INTENSIVE CARE UNITS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PRACTICE GUIDELINES AS TOPIC; PROSPECTIVE STUDIES; SHOCK, SEPTIC;

EID: 84875399070     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2012.06.015     Document Type: Article

References (17)

1. Bosetti C., Levi F., Lucchini F., Zatonski W.A., Negri E., La Vecchia C. Worldwide mortality from cirrhosis: an update to 2002. J Hepatol 2007, 46:827-839.
2. Alberti C., Brun-Buisson C., Burchardi H., et al. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med 2002, 28:108-121.
3. Wasmuth H.E., Kunz D., Yagmur E., et al. Patients with acute on chronic liver failure display 'sepsis-like' immune paralysis. J Hepatol 2005, 42:195-201.
4. Wong F., Bernardi M., Balk R., et al. Sepsis in cirrhosis: report on the 7th meeting of the international ascites club. Gut 2005, 54:718-725.
5. Austin M.J., Shawcross D.L. Outcome of patients with cirrhosis admitted to intensive care. Curr Opin Crit Care 2008, 14:202-207.
6. Jenq C.C., Tsai M.H., Tian Y.C., et al. RIFLE classification can predict short-term prognosis in critically ill cirrhotic patients. Intensive Care Med 2007, 33:1921-1930.
7. Dellinger R.P., Carlet J.M., Masur H., et al. Surviving Sepsis Campaign: guidelines for management of severe sepsis and septic shock. Crit Care Med 2004, 32:858-873.
8. Dellinger R.P., Levy M.M., Carlet J.M., et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock. Crit Care Med 2008, 36:296-327.
9. Ferrer R., Artigas A., Levy M.M., et al. Improvement in process of care and outcome after a multicenter severe sepsis educational program in Spain. JAMA 2008, 299:2294-2303.
10. Ferrer R., Artigas A. Effectiveness of treatment for severe sepsis: data from the bundle improvement program. Minerva Anestesiol 2011, 77:360-365.
11. Girardis M., Rinaldi L., Donno L., et al. Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study. Crit Care 2009, 13:R143.
12. Le Gall J.R., Lemeshow S., Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 1993, 270:2957-2963.
13. Vincent J.L., Moreno R., Takala J., et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med 1996, 22:707-710.
14. Kamath P.S., Wiesner R.H., Malinchoc M., et al. A model to predict survival in patients with end-stage liver disease. Hepatology 2001, 33:464-470.
15. Fernández J., Escorsell A., Zabalza M., et al. Adrenal insufficiency in patients with cirrhosis and septic shock: effect of treatment with hydrocortisone on survival. Hepatology 2006, 44:1288-1295.
16. Arabi Y.M., Aljumah A., Dabbagh O., et al. Low-dose hydrocortisone in patients with cirrhosis and septic shock: a randomized controlled trial. CMAJ 2010, 182:1971-1977.
17. Canabal J.M., Kramer D.J. Management of sepsis in patients with liver failure. Curr Opin Crit Care 2008, 14:189-197.