Hair Cell Regeneration

Encyclopedia of Neuroscience

Volumn , Issue , 2009, Pages 1005-1013

  Meyers, J R ^a,b   Hu, Z ^a   Lu, Z ^a   Corwin, J T ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b Assistant Professor in the University Libraries   (United States)

Author keywords

Auditory system; Balance; Cochlea; Deafness; Ear; Hair cell; Hearing; Regeneration; Repair; Stem cell; Vestibular system

Indexed keywords

EID: 84875379700     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-008045046-9.00249-7     Document Type: Chapter

References (19)

1. Bermingham-McDonogh O., Rubel E.W. Hair cell regeneration: Winging our way towards a sound future. Current Opinion in Neurobiology 2003, 13:119-126.
2. Fritzsch B., Beisel K.W., Hansen L.A. The molecular basis of neurosensory cell formation in ear development: A blueprint for hair cell and sensory neuron regeneration?. Bioessays 2006, 28:1181-1193.
3. Gale J.E., Meyers J.R., Periasamy A., Corwin J.T. Survival of bundle-less hair cells and subsequent bundle replacement in the bullfrog saccule. Journal of Neurobiology 2002, 50:81-92.
4. Grant K.A., Raible D.W., Piotrowski T. Regulation of latent sensory hair cell precursors by glia in the zebrafish lateral line. Neuron 2005, 45:69-80.
5. Gu R., Montcouquiol M., Marchionni M., Corwin J.T. Proliferative responses to growth factors decline rapidly during postnatal maturation of mammalian hair cell epithelia. European Journal of Neuroscience 2007, 25:1363-1372.
6. Hawkins R.D., Bashiardes S., Powder K.E., et al. Large scale gene expression profiles of regenerating inner ear sensory epithelia. PLoS ONE 2007, 2(6):e525. [online].
7. Holley M.C. Application of new biological approaches to stimulate sensory repair and protection. British Medical Bulletin 2002, 63:157-169.
8. Hu Z., Corwin J.T. Inner ear hair cells produced in vitro by a mesenchymal-to-epithelial transition. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:16675-16680.
9. Kelley M.W. Regulation of cell fate in the sensory epithelia of the inner ear. Nature Reviews Neuroscience 2006, 7:837-849.
10. Laine H., Doetzlhofer A., Mantela J., et al. p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis. Journal of Neuroscience 2007, 27(6):1434-1444.
11. Lee Y.-S., Liu F., Segil N. Transcriptional regulation of p27Kip1 directs a morphogenetic wave of cell cycle exit in the developing organ of Corti. Development 2006, 133:2817-2826.
12. Li H., Corrales C.E., Edge A., Heller S. Stem cells as therapy for hearing loss. Trends in Molecular Medicine 2004, 10:309-315.
13. Ma E.Y., Rubel E.W., Raible D.W. Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line. Journal of Neuroscience 2008, 28:2261-2273.
14. Matsui J.I., Haque A., Huss D., et al. Caspase inhibitors promote hair cell survival and vestibular function following aminoglycoside treatment in vivo. Journal of Neuroscience 2003, 23:6111-6122.
15. Meyers J.R., Corwin J.T. Shape change controls supporting cell proliferation in lesioned mammalian balance epithelium. Journal of Neuroscience 2007, 27:4313-4325.
16. Morest D.K., Cotanche D.A. Regeneration of the inner ear as a model of neural plasticity. Journal of Neuroscience Research 2004, 78:455-460.
17. Shou J., Zheng J.L., Gao W.-Q. Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1. Molecular and Cellular Neuroscience 2003, 23:169-179.
18. White P.M., Doetzlhofer A., Lee Y.S., Groves A.K., Segil N. Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. Nature 2006, 441:984-987.
19. Zakir M., Dickman J.D. Regeneration of vestibular otolith afferents after ototoxic damage. Journal of Neuroscience 2006, 26:2881-2893.