MicroRNA-132 is frequently down-regulated in ductal carcinoma in situ (DCIS) of breast and acts as a tumor suppressor by inhibiting cell proliferation

Pathology Research and Practice

Volumn 209, Issue 3, 2013, Pages 179-183

  Li, Shuai ^a,b,c   Meng, Huimin ^a,b,c   Zhou, Feng ^a,b,c   Zhai, Lili ^a,b,c   Zhang, Lina ^a,b,c   Gu, Feng ^a,b,c   Fan, Yu ^a,b,c   Lang, Ronggang ^a,b,c   Fu, Li ^a,b,c,d   Gu, Lin ^a,b,c   Qi, Liqiang ^a,b,c  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b KEY LABORATORY OF CANCER PREVENTION AND THERAPY   (China)

^c State Key Lab of Breast Cancer Research   (China)

^d 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics   (China)

Author keywords

Cell proliferation; Ductal carcinoma in situ (DCIS); MicroRNA; MiR 132

Indexed keywords

MICRORNA; MICRORNA 10B; MICRORNA 125B; MICRORNA 132; MICRORNA 145; MICRORNA 154 3P; MICRORNA 382 5P; MICRORNA 409 3P; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CARCINOGENESIS; CANCER CELL; CELL PROLIFERATION; CLINICAL ARTICLE; COLONY FORMATION; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRADUCTAL CARCINOMA; REAL TIME POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

ADULT; AGED; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; MICRORNAS; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84875376648     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2012.12.002     Document Type: Article

References (20)

1. Tavassoli F.A., Devilee P. Intraductal Proliferative Lesions: Pathology and Genetics of Tumors of the Breast and Female Genetic Organs 2003, International Agency for Research on Cancer (IARC) Press, Lyon, pp. 63-73.
2. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116(2):281-297.
3. Miska E.A. How microRNAs control cell division, differentiation and death. Curr. Opin. Genet. Dev. 2005, 15(5):563-568. 10.1016/j.gde.2005.08.005.
4. Esquela-Kerscher A., Slack F.J. Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer 2006, 6(4):259-269. 10.1038/nrc1840.
5. Calin G.A., Sevignani C., Dumitru C.D., Hyslop T., Noch E., Yendamuri S., et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. U. S. A. 2004, 101(9):2999-3004. 10.1073/pnas.0307323101.
6. Lu J., Getz G., Miska E.A., Alvarez-Saavedra E., Lamb J., Peck D., et al. MicroRNA expression profiles classify human cancers. Nature 2005, 435(7043):834-838. 10.1038/nature03702.
7. Volinia S., Calin G.A., Liu C.G., Ambs S., Cimmino A., Petrocca F., et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. U. S. A. 2006, 103(7):2257-2261. 10.1073/pnas.0510565103.
8. Ma L., Teruya-Feldstein J., Weinberg R.A. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007, 449(7163):682-688. 10.1038/nature06174.
9. Frankel L.B., Christoffersen N.R., Jacobsen A., Lindow M., Krogh A., Lund A.H. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem. 2008, 283(2):1026-1033. 10.1074/jbc.M707224200.
10. O'Donnell K.A., Wentzel E.A., Zeller K.I., Dang C.V., Mendell J.T. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005, 435(7043):839-843. 10.1038/nature03677.
11. Li S., Fu H., Wang Y., Tie Y., Xing R., Zhu J., et al. MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma. Hepatology 2009, 49(4):1194-1202. 10.1002/hep.22757.
12. Franken N.A., Rodermond H.M., Stap J., Haveman J., van Bree C. Clonogenic assay of cells in vitro. Nat. Protoc. 2006, 1(5):2315-2319. 10.1038/nprot.2006.339.
13. Zhu S., Wu H., Wu F., Nie D., Sheng S., Mo Y.Y. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res. 2008, 18(3):350-359. 10.1038/cr.2008.24.
14. Qian B., Katsaros D., Lu L., Preti M., Durando A., Arisio R., et al. High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1. Breast Cancer Res. Treat. 2009, 117(1):131-140. 10.1007/s10549-008-0219-7.
15. Qi L., Bart J., Tan L.P., Platteel I., Sluis T., Huitema S., et al. Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma. BMC Cancer 2009, 9:163. 10.1186/1471-2407-9-163.
16. Iorio M.V., Ferracin M., Liu C.G., Veronese A., Spizzo R., Sabbioni S., et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 2005, 65(16):7065-7070.
17. Michael M.Z., O'Connor S.M., van Holst Pellekaan N.G., Young G.P., James R.J. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol. Cancer Res. 2003, 1(12):882-891.
18. Wang S., Bian C., Yang Z., Bo Y., Li J., Zeng L., et al. miR-145 inhibits breast cancer cell growth through RTKN. Int. J. Oncol. 2009, 34(5):1461-1466.
19. Scott G.K., Goga A., Bhaumik D., Berger C.E., Sullivan C.S., Benz C.C. Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J. Biol. Chem. 2007, 282(2):1479-1486. 10.1074/jbc.M609383200.
20. Zhang S., Hao J., Xie F., Hu X., Liu C., Tong J., et al. Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development. Carcinogenesis 2011, 32(8):1183-1189. 10.1093/carcin/bgr105.