Optimization of pressurized liquid extraction using a multivariate chemometric approach for the determination of anticancer drugs in sludge by ultra high performance liquid chromatography-tandem mass spectrometry

Journal of Chromatography A

Volumn 1283, Issue , 2013, Pages 27-38

  Seira, Jordan ^a,b   Claparols, Catherine ^c,d   Joannis Cassan, Claire ^a   Albasi, Claire ^a   Montréjaud Vignoles, Mireille ^b   Sablayrolles, Caroline ^b  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

^d UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Anticancer drugs; Experimental design; Pressurized liquid extraction; Sludge; Tandem mass spectrometry; Ultra high performance liquid chromatography

Indexed keywords

ANTICANCER DRUG; PRESSURIZED LIQUID EXTRACTION; SLUDGE; TANDEM MASS SPECTROMETRY; ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES;

CHROMATOGRAPHY; DESIGN OF EXPERIMENTS; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OPTIMIZATION; SEWAGE SLUDGE; STATISTICS;

EXTRACTION;

CYCLOPHOSPHAMIDE; IFOSFAMIDE;

ARTICLE; CHEMOMETRIC ANALYSIS; EXTRACTION; LIMIT OF DETECTION; MULTIVARIATE ANALYSIS; PRESSURIZED LIQUID EXTRACTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; SLUDGE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION PROCESS;

ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FRANCE; LINEAR MODELS; LIQUID-LIQUID EXTRACTION; MULTIVARIATE ANALYSIS; PRESSURE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEWAGE; TANDEM MASS SPECTROMETRY; WATER POLLUTANTS, CHEMICAL;

EID: 84875371487     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2013.01.114     Document Type: Article

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