메뉴 건너뛰기




Volumn 9, Issue 2, 2013, Pages 160-168

Research and standardization in Alzheimer's trials: Reaching international consensus

Author keywords

Alzheimer's disease; Amyloid imaging; Biomarkers; Cerebral spinal fluid; Clinical outcomes; Diagnosis; Early detection; Magnetic resonance imaging

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; AUSTRALIA; CEREBROSPINAL FLUID ANALYSIS; CLINICAL TRIAL (TOPIC); COMPUTED TOMOGRAPHY SCANNER; CONSENSUS DEVELOPMENT; DIAGNOSTIC ACCURACY; DIET; EARLY DIAGNOSIS; GOLD STANDARD; HUMAN; LIFESTYLE; LIFESTYLE MODIFICATION; LONGITUDINAL STUDY; MEDICAL RESEARCH; NEUROIMAGING; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL ACTIVITY; PRIORITY JOURNAL; STANDARDIZATION;

EID: 84875371210     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2012.10.006     Document Type: Note
Times cited : (21)

References (53)
  • 2
    • 80053126841 scopus 로고    scopus 로고
    • Introduction to revised criteria for the diagnosis of Alzheimer's disease: National Institute on Aging and the Alzheimer's Association workgroup
    • C.R. Jack Jr., M. Albert, D.S. Knopman, G.M. McKhann, R.A. Sperling, M.C. Carrillo, and B. Thies Introduction to revised criteria for the diagnosis of Alzheimer's disease: National Institute on Aging and the Alzheimer's Association workgroup Alzheimers Dement 2011
    • (2011) Alzheimers Dement
    • Jack Jr., C.R.1    Albert, M.2    Knopman, D.S.3    McKhann, G.M.4    Sperling, R.A.5    Carrillo, M.C.6    Thies, B.7
  • 3
    • 79960798144 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup
    • G.M. McKhann, D.S. Knopman, H. Chertkow, B.T. Hyman, C.R. Jack Jr., and C.H. Kawas The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging and the Alzheimer's Association workgroup Alzheimers Dement 2011
    • (2011) Alzheimers Dement
    • McKhann, G.M.1    Knopman, D.S.2    Chertkow, H.3    Hyman, B.T.4    Jack Jr., C.R.5    Kawas, C.H.6
  • 4
    • 79960152625 scopus 로고    scopus 로고
    • Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup
    • R.A. Sperling, P.S. Aisen, L.A. Beckett, D.A. Bennett, S. Craft, and A.M. Fagan Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging and the Alzheimer's Association workgroup Alzheimers Dement 2011
    • (2011) Alzheimers Dement
    • Sperling, R.A.1    Aisen, P.S.2    Beckett, L.A.3    Bennett, D.A.4    Craft, S.5    Fagan, A.M.6
  • 5
    • 84863722678 scopus 로고    scopus 로고
    • Revised criteria for mild cognitive impairment may compromise the diagnosis of Alzheimer Disease dementia
    • J.C. Morris Revised criteria for mild cognitive impairment may compromise the diagnosis of Alzheimer Disease dementia Arch Neurol 2012
    • (2012) Arch Neurol
    • Morris, J.C.1
  • 6
    • 80955166367 scopus 로고    scopus 로고
    • Recommendations for the incorporation of biomarkers into Alzheimer clinical trials: An overview
    • J.C. Morris, and D.J. Selkoe Recommendations for the incorporation of biomarkers into Alzheimer clinical trials: an overview Neurobiol Aging 32 2011 S1 S3
    • (2011) Neurobiol Aging , vol.32
    • Morris, J.C.1    Selkoe, D.J.2
  • 8
    • 80055034288 scopus 로고    scopus 로고
    • Alzheimer's Prevention Initiative: A plan to accelerate the evaluation of presymptomatic treatments
    • E.M. Reiman, J.B. Langbaum, A.S. Fleisher, R.J. Caselli, K. Chen, and N. Ayutyanont Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments J Alzheimers Dis 26 2011 321 329
    • (2011) J Alzheimers Dis , vol.26 , pp. 321-329
    • Reiman, E.M.1    Langbaum, J.B.2    Fleisher, A.S.3    Caselli, R.J.4    Chen, K.5    Ayutyanont, N.6
  • 9
    • 83255181779 scopus 로고    scopus 로고
    • Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [11C]Pittsburgh compound B data
    • A.G. Vlassenko, M.A. Mintun, C. Xiong, Y.I. Sheline, A.M. Goate, and T.L. Benzinger Amyloid-beta plaque growth in cognitively normal adults: longitudinal [11C]Pittsburgh compound B data Ann Neurol 70 2011 857 861
    • (2011) Ann Neurol , vol.70 , pp. 857-861
    • Vlassenko, A.G.1    Mintun, M.A.2    Xiong, C.3    Sheline, Y.I.4    Goate, A.M.5    Benzinger, T.L.6
  • 10
    • 39749166965 scopus 로고    scopus 로고
    • The Mayo Clinic Study of Aging: Design and sampling, participation, baseline measures and sample characteristics
    • R.O. Roberts, Y.E. Geda, D.S. Knopman, R.H. Cha, V.S. Pankratz, and B.F. Boeve The Mayo Clinic Study of Aging: design and sampling, participation, baseline measures and sample characteristics Neuroepidemiology 30 2008 58 69
    • (2008) Neuroepidemiology , vol.30 , pp. 58-69
    • Roberts, R.O.1    Geda, Y.E.2    Knopman, D.S.3    Cha, R.H.4    Pankratz, V.S.5    Boeve, B.F.6
  • 11
    • 79960825638 scopus 로고    scopus 로고
    • How golden is the gold standard of neuropathology in dementia?
    • P. Scheltens, and K. Rockwood How golden is the gold standard of neuropathology in dementia? Alzheimers Dement 7 2011 486 489
    • (2011) Alzheimers Dement , vol.7 , pp. 486-489
    • Scheltens, P.1    Rockwood, K.2
  • 13
    • 79551713201 scopus 로고    scopus 로고
    • Brain microbleeds and Alzheimer's disease: Innocent observation or key player?
    • C. Cordonnier, and W.M. van der Flier Brain microbleeds and Alzheimer's disease: innocent observation or key player? Brain 134 2011 335 344
    • (2011) Brain , vol.134 , pp. 335-344
    • Cordonnier, C.1    Van Der Flier, W.M.2
  • 14
    • 79960817113 scopus 로고    scopus 로고
    • Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer's Association Research Roundtable Workgroup
    • R.A. Sperling, C.R. Jack Jr., S.E. Black, M.P. Frosch, S.M. Greenberg, and B.T. Hyman Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup Alzheimers Dement 7 2011 367 385
    • (2011) Alzheimers Dement , vol.7 , pp. 367-385
    • Sperling, R.A.1    Jack Jr., C.R.2    Black, S.E.3    Frosch, M.P.4    Greenberg, S.M.5    Hyman, B.T.6
  • 15
    • 84875363921 scopus 로고    scopus 로고
    • European Medicines Agency. Qualification opinion of low hippocampal volume (atrophy) by MRI for use in regulatory clinical trials in pre-dementia stage of Alzheimer's disease. Accessed April 2012
    • European Medicines Agency. Qualification opinion of low hippocampal volume (atrophy) by MRI for use in regulatory clinical trials in pre-dementia stage of Alzheimer's disease. Available at: < http://www.ema.europa.eu/docs/ en-GB/document-library/Regulatory-and-procedural-guideline/2011/10/WC500116264. pdf 11 >. Accessed April 2012.
  • 16
    • 79952710115 scopus 로고    scopus 로고
    • Harmonization of magnetic resonance-based manual hippocampal segmentation: A mandatory step for wide clinical use
    • G.B. Frisoni, and C.R. Jack Harmonization of magnetic resonance-based manual hippocampal segmentation: a mandatory step for wide clinical use Alzheimers Dement 7 2011 171 174
    • (2011) Alzheimers Dement , vol.7 , pp. 171-174
    • Frisoni, G.B.1    Jack, C.R.2
  • 17
    • 79960830268 scopus 로고    scopus 로고
    • Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease
    • e474
    • C.R. Jack Jr., F. Barkhof, M.A. Bernstein, M. Cantillon, P.E. Cole, and C. Decarli Steps to standardization and validation of hippocampal volumetry as a biomarker in clinical trials and diagnostic criterion for Alzheimer's disease Alzheimers Dement 7 2011 474 485 e474
    • (2011) Alzheimers Dement , vol.7 , pp. 474-485
    • Jack Jr., C.R.1    Barkhof, F.2    Bernstein, M.A.3    Cantillon, M.4    Cole, P.E.5    Decarli, C.6
  • 18
    • 84881343782 scopus 로고    scopus 로고
    • Delphi consensus on landmarks for the manual segmentation of the hippocampus on MRI: Preliminary results from the EADC-ADNI Harmonization Protocol Working Group (S04.003)
    • M. Boccardi, M. Bocchetta, L. Apostolova, J. Barnes, G. Bartzokis, and G. Corbetta Delphi consensus on landmarks for the manual segmentation of the hippocampus on MRI: preliminary results from the EADC-ADNI Harmonization Protocol Working Group (S04.003) Neurology 78 2012
    • (2012) Neurology , vol.78
    • Boccardi, M.1    Bocchetta, M.2    Apostolova, L.3    Barnes, J.4    Bartzokis, G.5    Corbetta, G.6
  • 20
    • 84865683216 scopus 로고    scopus 로고
    • Brain amyloid imaging-FDA approval of florbetapir F18 injection
    • L. Yang, D. Rieves, and C. Ganley Brain amyloid imaging-FDA approval of florbetapir F18 injection N Engl J Med 367 2012 885 887
    • (2012) N Engl J Med , vol.367 , pp. 885-887
    • Yang, L.1    Rieves, D.2    Ganley, C.3
  • 22
    • 79954748692 scopus 로고    scopus 로고
    • Cerebral amyloid-beta PET with florbetaben (18F) in patients with Alzheimer's disease and healthy control subjects: A multicentre phase 2 diagnostic study
    • H. Barthel, H.J. Gertz, S. Dresel, O. Peters, P. Bartenstein, and K. Buerger Cerebral amyloid-beta PET with florbetaben (18F) in patients with Alzheimer's disease and healthy control subjects: a multicentre phase 2 diagnostic study Lancet Neurol 10 2011 424 435
    • (2011) Lancet Neurol , vol.10 , pp. 424-435
    • Barthel, H.1    Gertz, H.J.2    Dresel, S.3    Peters, O.4    Bartenstein, P.5    Buerger, K.6
  • 23
    • 77956384880 scopus 로고    scopus 로고
    • 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: A phase 2 trial
    • R. Vandenberghe, K. Van Laere, A. Ivanoiu, E. Salmon, C. Bastin, and E. Triau 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial Ann Neurol 68 2010 319 329
    • (2010) Ann Neurol , vol.68 , pp. 319-329
    • Vandenberghe, R.1    Van Laere, K.2    Ivanoiu, A.3    Salmon, E.4    Bastin, C.5    Triau, E.6
  • 24
    • 77954338544 scopus 로고    scopus 로고
    • Characterization of AZD4694, a novel fluorinated Abeta plaque neuroimaging PET radioligand
    • A. Jureus, B.M. Swahn, J. Sandell, F. Jeppsson, A.E. Johnson, and P. Johnstrom Characterization of AZD4694, a novel fluorinated Abeta plaque neuroimaging PET radioligand J Neurochem 114 2010 784 794
    • (2010) J Neurochem , vol.114 , pp. 784-794
    • Jureus, A.1    Swahn, B.M.2    Sandell, J.3    Jeppsson, F.4    Johnson, A.E.5    Johnstrom, P.6
  • 25
    • 40449083016 scopus 로고    scopus 로고
    • Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias
    • L. Mosconi, W.H. Tsui, K. Herholz, A. Pupi, A. Drzezga, and G. Lucignani Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias J Nucl Med 49 2008 390 398
    • (2008) J Nucl Med , vol.49 , pp. 390-398
    • Mosconi, L.1    Tsui, W.H.2    Herholz, K.3    Pupi, A.4    Drzezga, A.5    Lucignani, G.6
  • 26
    • 84859406520 scopus 로고    scopus 로고
    • Summary metrics to assess Alzheimer's disease-related hypometabolic pattern with FDG-PET: Head-to-head comparison
    • A. Caroli, A. Prestia, K. Chen, N. Ayutyanont, S.M. Landau, and C.M. Madison Summary metrics to assess Alzheimer's disease-related hypometabolic pattern with FDG-PET: head-to-head comparison J Nucl Med 53 2012 592 600
    • (2012) J Nucl Med , vol.53 , pp. 592-600
    • Caroli, A.1    Prestia, A.2    Chen, K.3    Ayutyanont, N.4    Landau, S.M.5    Madison, C.M.6
  • 27
    • 0030023868 scopus 로고    scopus 로고
    • Alzheimer disease: Improved visual interpretation of PET images using three dimensional stereotaxic surface projections
    • J.H. Burdette, S. Minoshima, T. Vander Borght, D.E. Tran, and D.E. Kuhl Alzheimer disease: improved visual interpretation of PET images using three dimensional stereotaxic surface projections Radiology 198 1996 837 843
    • (1996) Radiology , vol.198 , pp. 837-843
    • Burdette, J.H.1    Minoshima, S.2    Vander Borght, T.3    Tran, D.E.4    Kuhl, D.E.5
  • 29
    • 76849104065 scopus 로고    scopus 로고
    • Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly
    • Y.I. Sheline, M.E. Raichle, A.Z. Snyder, J.C. Morris, D. Head, and S. Wang Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly Biol Psychiatry 67 2010 584 587
    • (2010) Biol Psychiatry , vol.67 , pp. 584-587
    • Sheline, Y.I.1    Raichle, M.E.2    Snyder, A.Z.3    Morris, J.C.4    Head, D.5    Wang, S.6
  • 30
    • 78650371044 scopus 로고    scopus 로고
    • APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Abeta42
    • Y.I. Sheline, J.C. Morris, A.Z. Snyder, J.L. Price, Z. Yan, and G. D'Angelo APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Abeta42 J Neurosci 30 2010 17035 17040
    • (2010) J Neurosci , vol.30 , pp. 17035-17040
    • Sheline, Y.I.1    Morris, J.C.2    Snyder, A.Z.3    Price, J.L.4    Yan, Z.5    D'Angelo, G.6
  • 31
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
    • K. Blennow, H. Hampel, M. Weiner, and H. Zetterberg Cerebrospinal fluid and plasma biomarkers in Alzheimer disease Nat Rev Neurol 6 2010 131 144
    • (2010) Nat Rev Neurol , vol.6 , pp. 131-144
    • Blennow, K.1    Hampel, H.2    Weiner, M.3    Zetterberg, H.4
  • 33
    • 84855304100 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia
    • P. Buchhave, L. Minthon, H. Zetterberg, A.K. Wallin, K. Blennow, and O. Hansson Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia Arch Gen Psychiatry 69 2012 98 106
    • (2012) Arch Gen Psychiatry , vol.69 , pp. 98-106
    • Buchhave, P.1    Minthon, L.2    Zetterberg, H.3    Wallin, A.K.4    Blennow, K.5    Hansson, O.6
  • 34
    • 80053385349 scopus 로고    scopus 로고
    • Qualification opinion of novel methodologies in the predementia stage of Alzheimer's disease: Cerebro-spinal fluid-related biomarkers for drugs affecting amyloid burden: Regulatory considerations by European Medicines Agency focusing in improving benefit/risk in regulatory trials
    • M. Isaac, S. Vamvakas, E. Abadie, B. Jonsson, C. Gispen, and L. Pani Qualification opinion of novel methodologies in the predementia stage of Alzheimer's disease: cerebro-spinal fluid-related biomarkers for drugs affecting amyloid burden: regulatory considerations by European Medicines Agency focusing in improving benefit/risk in regulatory trials Eur Neuropsychopharmacol 21 2011 781 788
    • (2011) Eur Neuropsychopharmacol , vol.21 , pp. 781-788
    • Isaac, M.1    Vamvakas, S.2    Abadie, E.3    Jonsson, B.4    Gispen, C.5    Pani, L.6
  • 35
    • 67650407720 scopus 로고    scopus 로고
    • Development of semagacestat (LY450139), a functional gamma-secretase inhibitor, for the treatment of Alzheimer's disease
    • D.B. Henley, P.C. May, R.A. Dean, and E.R. Siemers Development of semagacestat (LY450139), a functional gamma-secretase inhibitor, for the treatment of Alzheimer's disease Expert Opin Pharmacother 10 2009 1657 1664
    • (2009) Expert Opin Pharmacother , vol.10 , pp. 1657-1664
    • Henley, D.B.1    May, P.C.2    Dean, R.A.3    Siemers, E.R.4
  • 36
    • 84856638194 scopus 로고    scopus 로고
    • BACE1 inhibition induces a specific cerebrospinal fluid beta-amyloid pattern that identifies drug effects in the central nervous system
    • N. Mattsson, L. Rajendran, H. Zetterberg, M. Gustavsson, U. Andreasson, and M. Olsson BACE1 inhibition induces a specific cerebrospinal fluid beta-amyloid pattern that identifies drug effects in the central nervous system PLoS One 7 2012 e31084
    • (2012) PLoS One , vol.7 , pp. 31084
    • Mattsson, N.1    Rajendran, L.2    Zetterberg, H.3    Gustavsson, M.4    Andreasson, U.5    Olsson, M.6
  • 37
    • 78149330220 scopus 로고    scopus 로고
    • Biomarkers in Alzheimer's disease drug development
    • K. Blennow Biomarkers in Alzheimer's disease drug development Nat Med 16 2010 1218 1222
    • (2010) Nat Med , vol.16 , pp. 1218-1222
    • Blennow, K.1
  • 38
    • 34248327182 scopus 로고    scopus 로고
    • Diagnostic accuracy of ELISA and xMAP technology for analysis of amyloid beta(42) and tau proteins
    • T.S. Reijn, M.O. Rikkert, W.J. van Geel, D. de Jong, and M.M. Verbeek Diagnostic accuracy of ELISA and xMAP technology for analysis of amyloid beta(42) and tau proteins Clin Chem 53 2007 859 865
    • (2007) Clin Chem , vol.53 , pp. 859-865
    • Reijn, T.S.1    Rikkert, M.O.2    Van Geel, W.J.3    De Jong, D.4    Verbeek, M.M.5
  • 39
    • 77955944439 scopus 로고    scopus 로고
    • Lessons from multicenter studies on CSF biomarkers for Alzheimer's disease
    • N. Mattsson, H. Zetterberg, and K. Blennow Lessons from multicenter studies on CSF biomarkers for Alzheimer's disease Int J Alzheimers Dis 2010
    • (2010) Int J Alzheimers Dis
    • Mattsson, N.1    Zetterberg, H.2    Blennow, K.3
  • 40
    • 80051758766 scopus 로고    scopus 로고
    • Preanalytical sample handling and sample stability testing for the neurochemical dementia diagnostics
    • R. Zimmermann, N. Lelental, O. Ganslandt, J.M. Maler, J. Kornhuber, and P. Lewczuk Preanalytical sample handling and sample stability testing for the neurochemical dementia diagnostics J Alzheimers Dis 25 2011 739 745
    • (2011) J Alzheimers Dis , vol.25 , pp. 739-745
    • Zimmermann, R.1    Lelental, N.2    Ganslandt, O.3    Maler, J.M.4    Kornhuber, J.5    Lewczuk, P.6
  • 41
    • 79960764322 scopus 로고    scopus 로고
    • The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers
    • e386
    • N. Mattsson, U. Andreasson, S. Persson, H. Arai, S.D. Batish, and S. Bernardini The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers Alzheimers Dement 7 2011 386 395 e386
    • (2011) Alzheimers Dement , vol.7 , pp. 386-395
    • Mattsson, N.1    Andreasson, U.2    Persson, S.3    Arai, H.4    Batish, S.D.5    Bernardini, S.6
  • 46
    • 52349120531 scopus 로고    scopus 로고
    • Changes in cognition and mortality in relation to exercise in late life: A population based study
    • L.E. Middleton, A. Mitnitski, N. Fallah, S.A. Kirkland, and K. Rockwood Changes in cognition and mortality in relation to exercise in late life: a population based study PLoS One 3 2008 e3124
    • (2008) PLoS One , vol.3 , pp. 3124
    • Middleton, L.E.1    Mitnitski, A.2    Fallah, N.3    Kirkland, S.A.4    Rockwood, K.5
  • 47
    • 4544370551 scopus 로고    scopus 로고
    • Physical activity, including walking, and cognitive function in older women
    • J. Weuve, J.H. Kang, J.E. Manson, M.M. Breteler, J.H. Ware, and F. Grodstein Physical activity, including walking, and cognitive function in older women JAMA 292 2004 1454 1461
    • (2004) JAMA , vol.292 , pp. 1454-1461
    • Weuve, J.1    Kang, J.H.2    Manson, J.E.3    Breteler, M.M.4    Ware, J.H.5    Grodstein, F.6
  • 48
    • 84881188629 scopus 로고    scopus 로고
    • Physical activity and amyloid-beta plasma and brain levels: Results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing
    • B.M. Brown, J.J. Peiffer, K. Taddei, J.K. Lui, S.M. Laws, and V.B. Gupta Physical activity and amyloid-beta plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing Mol Psychiatry 2012
    • (2012) Mol Psychiatry
    • Brown, B.M.1    Peiffer, J.J.2    Taddei, K.3    Lui, J.K.4    Laws, S.M.5    Gupta, V.B.6
  • 49
    • 68849101447 scopus 로고    scopus 로고
    • Adherence to a Mediterranean diet, cognitive decline, and risk of dementia
    • C. Feart, C. Samieri, V. Rondeau, H. Amieva, F. Portet, and J.F. Dartigues Adherence to a Mediterranean diet, cognitive decline, and risk of dementia JAMA 302 2009 638 648
    • (2009) JAMA , vol.302 , pp. 638-648
    • Feart, C.1    Samieri, C.2    Rondeau, V.3    Amieva, H.4    Portet, F.5    Dartigues, J.F.6
  • 51
    • 79951931265 scopus 로고    scopus 로고
    • Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population
    • C.C. Tangney, M.J. Kwasny, H. Li, R.S. Wilson, D.A. Evans, and M.C. Morris Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population Am J Clin Nutr 93 2011 601 607
    • (2011) Am J Clin Nutr , vol.93 , pp. 601-607
    • Tangney, C.C.1    Kwasny, M.J.2    Li, H.3    Wilson, R.S.4    Evans, D.A.5    Morris, M.C.6
  • 52
    • 84875365312 scopus 로고    scopus 로고
    • Global Alzheimer's Association Interactive Network,. Accessed April
    • Global Alzheimer's Association Interactive Network, www.gaain.org. Accessed April 2012.
    • (2012)
  • 53
    • 84860482269 scopus 로고    scopus 로고
    • Common Alzheimer's research ontology: National Institute on Aging and Alzheimer's Association collaborative project
    • L.M. Refolo, H. Snyder, C. Liggins, L. Ryan, N. Silverberg, and S. Petanceska Common Alzheimer's research ontology: National Institute on Aging and Alzheimer's Association collaborative project Alzheimers Dement 8 2012
    • (2012) Alzheimers Dement , vol.8
    • Refolo, L.M.1    Snyder, H.2    Liggins, C.3    Ryan, L.4    Silverberg, N.5    Petanceska, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.