Scalable Technology for the Extraction of Pharmaceutics: Outcomes from a 3 year collaborative industry/academia research programme

Journal of Chromatography A

Volumn 1282, Issue , 2013, Pages 84-94

  Sutherland, Ian ^a   Thickitt, Chris ^b   Douillet, Nathalie ^b   Freebairn, Keith ^b   Johns, David ^b   Mountain, Clive ^b   Wood, Philip ^c   Edwards, Neil ^c   Rooke, David ^c   Harris, Guy ^c   Keay, David ^c   Mathews, Ben ^d   Brown, Roland ^d   Garrard, Ian ^a   Hewitson, Peter ^a   Ignatova, Svetlana ^a  

^a BRUNEL UNIVERSITY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Dynamic Extractions Ltd   (United Kingdom)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

High performance counter current chromatography; HPCCC; Process scale; Scale up

Indexed keywords

COUNTERCURRENT CHROMATOGRAPHY; HIGH VALUE MANUFACTURING; HPCCC; PHARMACEUTICAL INDUSTRY; PROCESS SCALE; SCALE-UP; SCIENTIFIC DEVELOPMENT; SILICA-GEL CHROMATOGRAPHY;

ISOMERS; LIQUID CHROMATOGRAPHY; MANUFACTURE; REMOVAL; RESEARCH; SILICA GEL;

TECHNOLOGY;

DRUG;

ARTICLE; COST EFFECTIVENESS ANALYSIS; DRUG IMPURITY; DRUG INDUSTRY; DRUG MANUFACTURE; DRUG PURITY; DRUG RESEARCH; DRUG SOLUBILITY; GEL CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; ISOMER; PRIORITY JOURNAL; SEPARATION TECHNIQUE;

COUNTERCURRENT DISTRIBUTION; DRUG INDUSTRY; ISOMERISM; MODELS, CHEMICAL; ORGANIC CHEMICALS; PHARMACEUTICAL PREPARATIONS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84875364421     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2013.01.049     Document Type: Article

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