Periimplant histology and cytokine pattern in metal-allergic knee arthroplasty patients with improvement after revision with hypoallergenic materials

Seminars in Arthroplasty JSES

Volumn 23, Issue 4, 2012, Pages 268-272

  Thomas, Peter ^a   Von der Helm, Christine ^a   Schopf, Christoph ^a   Thomsen, Marc ^b   Frommelt, Lars ^c   Schneider, Josef ^a   Flaig, Michael ^a   Krenn, Veit ^d   Mazoochian, Farhad ^a   Summer, Burkhard ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b Orthopedic DRK Clinic   (Germany)

^c ENDO Klinik   (Germany)

^d Institute of Pathology   (Germany)

Author keywords

Allergy; Arthroplasty; Cytokine; Histology; Knee; Metal

Indexed keywords

BONE CEMENT; CHROMIUM; COBALT; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; MANGANESE; MOLYBDENUM; NICKEL; TITANIUM; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VANADIUM;

ADULT; AGED; ALLERGY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; KNEE ARTHROPLASTY; LYMPHOCYTE TRANSFORMATION TEST; MALE; METAL ALLERGY; PATCH TEST; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PROSTHESIS MATERIAL; PROTEIN EXPRESSION; REOPERATION; SENSITIZATION; T LYMPHOCYTE; WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX;

EID: 84875322421     PISSN: 10454527     EISSN: 15584437     Source Type: Journal    
DOI: 10.1053/j.sart.2013.01.011     Document Type: Article

References (13)

1. Schäfer T., Böhler E., Ruhdorfer S., et al. Epidemiology of contact allergy in adults. Allergy 2001, 56(12):1192-1196.
2. Thomas P., Schuh A., Ring J., et al. Orthopedic surgical implants and allergies: joint statement by the implant allergy working group (AK 20) of the DGOOC (German association of orthopedics and orthopedic surgery), DKG (German contact dermatitis research group) and dgaki (German society for allergology and clinical immunology). Orthopäde 2008, 37(1):75-88.
3. Summer B., Paul C., Mazoochian F., et al. Nickel (Ni) allergic patients with complications to Ni containing joint replacement show preferential IL-17 type reactivity to Ni. Contact Dermatitis 2010, 63(1):15-22.
4. Krenn V., Morawietz L., Jakobs M., et al. Joint endoprosthesis pathology. Histopathological diagnostics and classification. Pathologe 2011, 32(3):210-219.
5. Kubba R., Taylor J.S., Marks K.E. Cutaneous complications of orthopedic implants. A two-year prospective study. Arch Dermatol 1981, 117(9):554-560.
6. Davies A.P., Willert H.G., Campbell P.A., et al. An unusual lymphocytic perivascular infiltration in tissues around contemporary metal-on-metal joint replacements. J Bone Joint Surg Am 2005, 87(1):18-27.
7. Willert H.G., Buchhorn G.H., Fayyazi A., et al. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints. A clinical and histomorphological study. J Bone Joint Surg Am 2005, 87(1):28-36.
8. Granchi D., Cenni E., Trisolino G., et al. Sensitivity to implant materials in patients undergoing total hip replacement. J Biomed Mater Res B Appl Biomater 2006, 77(2):257-264.
9. Hallab N.J., Anderson S., Stafford T., et al. Lymphocyte responses in patients with total hip arthroplasty. J Orthop Res 2005, 23(2):384-391.
10. Thomas P., Braathen L.R., Dorig M., et al. Increased metal allergy in patients with failed metal-on-metal hip arthroplasty and peri-implant T-lymphocytic inflammation. Allergy 2009, 64(8):1157-1165.
11. Anand A., McGlynn F., Jiranek W. Metal hypersensitivity: can it mimic infection?. J Arthroplasty 2009, 24(5):826-828.
12. Ng V.Y., Lombardi A.V., Berend K.R., et al. Perivascular lymphocytic infiltration is not limited to metal-on-metal bearings. Clin Orthop Relat Res 2011, 469(2):523-529.
13. Langton D.J., Joyce T.J., Jameson S.S., et al. Adverse reaction to metal debris following hip resurfacing: the influence of component type, orientation and volumetric wear. J Bone Joint Surg Br 2011, 93(2):164-171.