Tacrolimus monotherapy following alemtuzumab induction in combined kidney-pancreas transplantation: Results of a prospective randomized trial

Annals of Transplantation

Volumn 17, Issue 4, 2012, Pages 45-51

  Bösmüller, Claudia ^a   Öllinger, Robert ^a   Sieb, Michael ^a   Weissenbacher, Annemarie ^a   Schneeberger, Stefan ^a   Pratschke, Johann ^a   Margreiter, Raimund ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Alemtuzumab; Kidney transplant; Pancreas transplant; Tacrolimus

Indexed keywords

ALEMTUZUMAB; CREATININE; GLUCOSE; HEMOGLOBIN A1C; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS;

ACUTE GRAFT REJECTION; ADULT; ARTICLE; BACTERIAL INFECTION; BLOOD PRESSURE; CARDIOVASCULAR DISEASE; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFECTIOUS COMPLICATION; KIDNEY PANCREAS TRANSPLANTATION; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; MYCOSIS; NEUROLOGICAL COMPLICATION; PNEUMONIA; POSTOPERATIVE COMPLICATION; REVASCULARIZATION; SEPTICEMIA; THROMBOSIS; VEIN GRAFT DISEASE; VIRUS INFECTION;

ADOLESCENT; ADULT; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTILYMPHOCYTE SERUM; DIABETES MELLITUS, TYPE 1; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INDUCTION CHEMOTHERAPY; KAPLAN-MEIER ESTIMATE; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MAINTENANCE CHEMOTHERAPY; MALE; METHYLPREDNISOLONE; MIDDLE AGED; MYCOPHENOLIC ACID; PANCREAS TRANSPLANTATION; PROSPECTIVE STUDIES; TACROLIMUS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84875291377     PISSN: 14259524     EISSN: None     Source Type: Journal    
DOI: 10.12659/AOT.883693     Document Type: Article

References (7)

1. Margreiter R, Klempnauer J, Neuhaus P et al: Alemtuzumab (Campath-1H) and tacrolimus monotherapy after renal transplantation: results of a prospective randomized trial. Am J Transplant, 2008; 8(7): 1480-85
2. Thai NL, Khan A, Tom K et al: Alemtuzumab induction and tacrolimus monotherapy in pancreas transplantation: One and two years outcomes. Transplantation. 2006; 82(12): 1621-24
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5. Muthusamy AS, Vaidya AC, Sinha S et al: Alemtuzumab induction and steroid-free maintenance immunosuppression in pancreas transplantation. Am J Transplant, 2008; 8(10): 2126-31
6. Reddy KS, Devarapalli Y, Mazur M et al: Alemtuzumab with rapid steroid taper in simultaneous kidney and pancreas transplantation: comparison to induction with antithymocyte globulin. Transplant Proc, 2010; 42(6): 2006-8
7. Uemura T, Ramprasad V, Matsushima K et al: Single dose of alemtuzumab induction with steroid-free maintenance immunosuppression in pancreas transplantation. Transplantation, 2011; 92(6): 678-85