The interaction between the oxytocin and pain modulation in headache patients

Neuropeptides

Volumn 47, Issue 2, 2013, Pages 93-97

  Wang, Yong Liang ^b   Yuan, Yan ^b   Yang, Jun ^a   Wang, Chang Hong ^a   Pan, Yan Juan ^a   Lu, Lu ^a   Wu, Yu Quan ^c   Wang, Da Xin ^d   Lv, Lu Xian ^a   Li, Ren Ren ^e   Xue, Lei ^f   Wang, Xin Hua ^g   Bi, Jian Wei ^h   Liu, Xin Feng ⁱ   Qian, Yan Ning ^j   Deng, Zhi Kuan ^k   Zhang, Zhi Jian ^l   Zhai, Xin Huan ^m   Zhou, Xin Jian ⁿ   Wang, Guo Liang ^o   Zhai, Jian Xin ^p   Liu, Wen Yan ^q   more..

^a XINXIANG MEDICAL UNIVERSITY   (China)

^b The First Affiliated Hospital of Xinxiang Medical University   (China)

^c 117 Hospital of People's Liberation Army   (China)

^d YANGZHOU UNIVERSITY   (China)

^e Guangdong 999 Brain Hospital   (China)

^f FIRST MILITARY MEDICAL UNIVERSITY   (China)

^g TONGJI UNIVERSITY   (China)

^h SECOND MILITARY MEDICAL UNIVERSITY   (China)

ⁱ NANJING GENERAL HOSPITAL OF NANJING MILITARY COMMAND   (China)

^j THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^k THIRD MILITARY MEDICAL UNIVERSITY   (China)

^l FUZHOU GENERAL HOSPITAL   (China)

^m 95 Hospital of People's Liberation Army   (China)

ⁿ People's Liberation Army 101 Hospital   (China)

^o GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

^p Fourth People's Hospital   (China)

^q JINING MEDICAL UNIVERSITY   (China)

more..

Author keywords

Headache; Human; Intranasal administration; Oxytocin

Indexed keywords

OXYTOCIN; PLACEBO;

ADULT; AGED; ARTICLE; CENTRAL NERVOUS SYSTEM; CEREBROSPINAL FLUID; CHINESE; CIRCULATION; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROMODULATION; OLFACTORY TRACT; PAIN; PRIORITY JOURNAL;

ADMINISTRATION, INTRANASAL; ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEADACHE; HUMANS; MALE; MIDDLE AGED; OXYTOCIN; PAIN; PAIN MEASUREMENT; YOUNG ADULT;

RATTUS;

EID: 84875279700     PISSN: 01434179     EISSN: 15322785     Source Type: Journal    
DOI: 10.1016/j.npep.2012.12.003     Document Type: Article

References (23)

1. Antunes J.L., Zimmerman E.A. The hypothalamic magnocellular system of the rhesus monkey: an immunocytochemical study. J. Comp. Neurol. 1978, 181:539-565.
2. Brown D.C., Perkowski S. Oxytocin content of the cerebrospinal fluid of dogs and its relationship to pain induced by spinal cord compression. Vet. Surg. 1998, 27:607-611.
3. Dhuria S.V., Hanson L.R., Frey W.H. Intranasal delivery to the central nervous system: mechanisms and experimental considerations. J. Pharm. Sci. 2010, 99:1654-1673.
4. Huffmeijer R., Alink L.R., Tops M., Grewen K.M., Light K.C., Bakermans-Kranenburg M.J., Ijzendoorn M.H. Salivary levels of oxytocin remain elevated for more than two hours after intranasal oxytocin administration. Neuro. Endocrinol. Lett. 2012, 33:21-25.
5. Illum L. Is nose-to-brain transport of drugs in man a reality?. J. Pharm. Pharmacol. 2004, 56:3-17.
6. MacDonald E., Dadds M.R., Brennan J.L., Williams K., Levy F., Cauchi A.J. A review of safety, side-effects and subjective reactions to intranasal oxytocin in human research. Psychoneuroendocrinology 2011, 36:1114-1126.
7. Madrazo I., Franco-Bourland R.E., Leon-Meza V.M., Mena I. Intraventricular somatostatin-14, arginine vasopressin, and oxytocin: analgesic effect in a patient with intractable cancer pain. Appl. Neurophysiol. 1987, 50:427-431.
8. McEwen B.B. The Role of Vasopressin and Oxytocin in Memory Processing 2004, vol. 50. Elsevier Science, Amsterdam.
9. Pan Y.J., Yin Z.K., Yang J., Zhao Y., Yan X.Q., Qiu P.Y., Wang D.X. Oxytocin in rat nucleus raphe magnus influences pain modulation. World J. Neurosci. 2012, 2(2). [Publish on line].
10. Pietrowsky R., Strüben C., Mölle M., Fehm H.L., Born J. Brain potential changes after intranasal vs. intravenous administration of vasopressin: evidence for a direct nose-brain pathway for peptide effects in humans. Biol. Psychiatry 1996, 39:332-340.
11. Song C.Y., Cui Y.Y., Wang C.H., Liu Z., Lin B.C. Preparation for anti-oxytocin serum and its radioimmunoassay. Chin. J. Nucl. Med. 1987, 7:224-227.
12. Uvnas-Moberg K., Alster P., Petersson M., Sohlstrom A., Bjorkstrand E. Postnatal oxytocin injections cause sustained weight gain and increased nociceptive thresholds in male and female rats. Pediatr. Res. 1998, 43:344-348.
13. Veronesi M.C., Kubek D.J., Kubek M.J. Intranasal delivery of neuropeptides. Methods Mol. Biol. 2011, 789:303-312.
14. Weisman O., Zagoory-Sharon O., Feldman R. Intranasal oxytocin administration is reflected in human saliva. Psychoneuroendocrinology 2012, 37:1582-1586.
15. Yang J. Intrathecal administration of oxytocin induces analgesia in low back pain involving the endogenous opiate peptides system. Spine 1994, 9:867-871.
16. Yang J., Li P., Liang J.Y., Pan Y.J., Yan X.Q., Yan F.L., Hao F., Zhang X.Y., Qiu P.Y., Wang D.X. Oxytocin in the periaqueductal gray regulates nociception in the rats. Regul. Pept. 2011, 169:39-42.
17. Yang J., Liang J.Y., Li P., Pan Y.J., Qiu P.Y., Zhang J., Hao F., Wang D.X. Oxytocin in the periaqueductal gray participates in pain modulation in the rat by influencing the endogenous opiate peptides. Peptides 2011, 32:1255-1261.
18. Yang J., Liang J.Y., Zhang X.Y., Qiu P.Y., Pang Y.J., Li P., Zhang J., Hao F., Wang D.X., Yan F.L. Oxytocin, but not arginine vasopressin is involving in the antinociceptive role of hypothalamic suproptic nucleus. Peptides 2011, 32:1042-1046.
19. Yang J., Pan Y.J., Zhao Y., Qiu P.Y., Lu L., Li P., Chen F., Yan X.Q., Wang D.X. Oxytocin in the rat caudate nucleus influences pain modulation. Peptides 2011, 32:2104-2107.
20. Yang J., Yang Y., Chen J.M., Liu W.Y., Wang C.H., Lin B.C. Central oxytocin enhances antinociception in the rat. Peptides 2007, 28:1113-1119.
21. Yang J., Yang Y., Chen J.M., Liu W.Y., Wang C.H., Lin B.C. Effect of hypothalamic supraoptic nucleus on acupuncture analgesia in the rat. Brain Res. Bull. 2008, 75:681-686.
22. Yang J., Yang Y., Chen J.M., Liu W.Y., Wang C.H., Lin B.C. Effect of oxytocin on acupuncture analgesia in the rat. Neuropeptides 2007, 41:285-292.
23. Yang J., Yang Y., Chen J.M., Liu W.Y., Wang C.H., Lin B.C. Investigating the role of the hypothalamic supraoptic nucleus in nociception in the rat. Life Sci. 2008, 82:166-173.